Zeltas
Zeltas Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Zeltas is a brand name. Its generic name is Azelastine + Fluticasone Propionate.
Zeltas Introduction
Zeltas is a fixed-dose combination medication used to treat allergic rhinitis (hay fever). The active ingredients of the combination medication are azelastine hydrochloride, an antihistamine, and fluticasone propionate, a glucocorticosteroid. Zeltas is a combination medication used to reduce the symptoms of hay fever including sneezing, itching, runny nose, and congestion.Uses for Zeltas
Zeltas is used to relieve the symptoms of allergic rhinitis, e.g. sneezing, itching, runny nose, and congestion. It is also used to treat nasal polyps.Mechanism of Action
Zeltas works by blocking the action of certain chemical messengers that are responsible for allergic reactions in the body. Azelastine is an antihistamine and works by blocking histamine, a chemical messenger that is responsible for allergic symptoms such as runny nose, sneezing, itching, and congestion. Fluticasone propionate is a glucocorticosteroid and works by suppressing inflammation and decreasing the activity of the immune system.How Long Does It Take to Work?
Zeltas starts to work immediately after you take it. Generally, it takes about 7 to 10 days for the drug to reach its full effect.Absorption
Zeltas is rapidly absorbed by the body after oral administration.Route of Elimination
Zeltas is eliminated primarily via the urine and, to a lesser extent, the feces.Dosage
The recommended dose of Zeltas depends on the patient’s age, weight, and condition. For adults and adolescents 12 years or older, the usual dose is one spray, 0.156 mg azelastine and 50 mcg fluticasone propionate, in each nostril twice daily. The dose for children 6 to 11 years of age is one spray, 0.156 mg of azelastine and 25 mcg of fluticasone propionate, in each nostril twice daily.Administration
Zeltas should be administered by the intranasal route only. This medication should be sprayed into the external nares (nostrils).Side Effects
Common side effects of Zeltas include headache, nosebleed, sore throat, cough, nasal discomfort, nose burning/stinging, joint/muscle pain, change in taste, coughing up blood, and difficulty sleeping.Toxicity
The toxicity of Zeltas is low. When used as directed, it is not expected to cause serious or life-threatening side effects.Precaution
Zeltas should be used with caution in people with a known sensitivity or allergy to azelastine, fluticasone, or any other ingredients found in this medication. It should also be used cautiously in people with active or quiescent tuberculosis, as it may worsen the condition.Interaction
Zeltas may interact with other medications, so it is important to tell your healthcare provider about any other medications you are taking, including prescription, over-the-counter, vitamins, herbal supplements, and other alternative medicines.Disease Interaction
Zeltas may interact with some diseases and conditions, so it is important to tell your healthcare provider about any other medical conditions you may have, including a history of tuberculosis.Drug Interactions
Zeltas may interact with some other medications. It is important to tell your healthcare provider about all other medications you are taking, including prescription, over-the-counter, vitamins, herbal supplements, and other alternative medicines.Food Interactions
Zeltas may interact with some foods, so it is important to tell your healthcare provider about any food items you are consuming.Pregnancy Use
Zeltas is not recommended for use by pregnant women.Lactation Use
Zeltas should be used with caution in women who are breastfeeding. It is not known if the active ingredients of the medication passes into breast milk.Acute Overdose
There is no specific antidote for an acute overdose of Zeltas. Symptoms of overdose may include dizziness, nausea, vomiting, blurred vision, and drowsiness.Contraindication
Zeltas is contraindicated for use in people who are known to be hypersensitive to azelastine or fluticasone, or any of the other ingredients in the medication.Use Direction
Zeltas should be used as directed by your healthcare provider. The medication should be sprayed into each nostril twice daily. It is important to not exceed the recommended dose as this may cause an increased risk of side effects.Storage Condition
Zeltas should be stored at room temperature away from moisture and direct light.Volume of Distribution
The volume of distribution for Zeltas is 6.4L.Half-Life
The half-life of Zeltas is 8.2 hours.Clearance
The clearance of Zeltas is 18.8L/hr.Here you find in details version of Zeltas