Z-Lidocain Plus

Z-Lidocain Plus Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Z-Lidocain Plus is a brand name. Its generic name is Lidocaine + Epinephrine.

Introduction

Z-Lidocain Plus is a local anesthetic and vasoconstrictor combination medication for use in surgical procedures. It is typically given as a drug before or after a procedure to block the sensation of pain and minimize bleeding.

Uses

Z-Lidocain Plus is used to block the sensations of pain in a surgical procedure or procedure performed without an incision. It helps reduce the bleeding and chances of infection which can occur with a procedure.

Mechanism of Action

Lidocaine is an anesthetic, and works by blocking the nerves conducting pain to the brain and sending nerve signals to the muscles to relax. The epinephrine in this medication causes the blood vessels to constrict, reducing the amount of blood flow to the area. This helps to reduce the bleeding during a procedure or surgery.

How Long Does It Take to Work?

It typically takes 1-2 minutes for lidocaine + epinephrine to take effect.

Absorption

Lidocaine + epinephrine is rapidly and completely absorbed from the injection site.

Route of Elimination

Lidocaine + epinephrine is mostly metabolized in the liver and excreted in the urine.

Dosage

The dose of lidocaine + epinephrine depends on the patient and the procedure being performed. The usual dose for adults is 0.5-3 mL.

Administration

Lidocaine + epinephrine can be given by injection directly into the tissue. It can also be administered topically or as a spray.

Side Effect

The most common side effects of lidocaine + epinephrine include skin irritation, numbness, rash, headache, dizziness, lightheadedness, and nausea.

Toxicity

Lidocaine + epinephrine is generally well-tolerated, but can cause serious adverse reactions such as seizures and breathing difficulty if given in excessive amounts or if someone is allergic to it.

Precaution

Lidocaine + epinephrine should not be used in patients with alcohol or drug abuse, kidney or liver problems, or certain heart conditions.

Interaction

Lidocaine + epinephrine may interact with other medications, such as narcotics, anticoagulants, diuretics, and MAO inhibitors.

Disease Interaction

There are no known disease interactions with lidocaine + epinephrine.

Drug Interaction

Lidocaine + epinephrine may interact with other drugs such as narcotics, anticoagulants, diuretics, and MAO inhibitors.

Food Interactions

Lidocaine + epinephrine does not interact with food.

Pregnancy Use

Lidocaine + epinephrine should generally not be used during pregnancy unless specifically indicated by a physician.

Lactation Use

Lidocaine + epinephrine should not be used during breastfeeding as it can pass into the milk and cause serious health issues for the infant.

Acute Overdose

Signs of an acute overdose of lidocaine + epinephrine include drowsiness, confusion, dizziness, cardiovascular collapse, and seizures.

Contraindication

Lidocaine + epinephrine should not be used in patients with a known allergy to lidocaine or epinephrine and in patients with certain heart conditions.

Use Direction

Lidocaine + epinephrine should only be used as directed by a physician.

Storage Condition

Lidocaine + epinephrine should be stored in a cool, dry place and away from light and moisture.

Volume of Distribution

The volume of distribution for lidocaine + epinephrine is 3-7 L/kg.

Half Life

The half-life of lidocaine + epinephrine is 1.5-2 hours.

Clearance

The clearance of lidocaine + epinephrine is 2.1-3.5 mL/min/kg.

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