Xylone Plus

Xylone Plus Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Xylone Plus is a brand name. Its generic name is Lidocaine + Prilocaine.

Introduction of Lidocaine and Prilocaine

Lidocaine and Prilocaine are local anesthetics that are combined to form a eutectic mixture of local anesthetics (EMLA). They are both amide-type anesthetics.

Uses for Lidocaine and Prilocaine

EMLA is used on normal intact skin as a topical anaesthetic to relieve pain before minor procedures such as venipuncture and laser treatment. It can be used to reduce discomfort during laser tattoo removal and can also be used to anaesthetize the perianal area during a rectal exam.

Mechanism of Action

Lidocaine works by temporarily disabling the nerves that carry pain signals from the skin to the brain while Prilocaine reduces the amount of neurotransmitters that are released when a nerve is stimulated. Together, they provide a stronger and longer lasting anaesthesia than either anesthetic alone.

How Long Does It Take to Work?

The effects of EMLA usually begin within 5 minutes of application and last up to four hours.

Absorption

EMLA is quickly and almost completely absorbed through the stratum corneum (outer layer of skin). It is then metabolized in the dermis (middle layer) before entering the bloodstream.

Route of Elimination

Lidocaine and Prilocaine are both metabolized in the liver and eliminated through the kidneys.

Dosage and Administration

EMLA is available as a cream that should be applied to affected area, as instructed by your doctor. Depending on the area being treated, your doctor may tell you to apply the cream 30 minutes to a few hours before your procedure.

Side Effects of Lidocaine and Prilocaine

The most common side effects of EMLA are reversible local skin reactions such as:

  • Burning sensation
  • Pain
  • Itching
More serious effects include nervous system depression and convulsions.

Toxicity

Overdose symptoms may include confusion, numbness, slowed breathing, seizures, unconsciousness, coma, and death. If an overdose occurs, get emergency medical help.

Precautions

EMLA should not be used in patients who are sensitive to any of its components, or have open wounds, cuts, scrapes, or sores near the site of application. It should also not be used in areas affected by frostbite and should be avoided in infants and premature babies.

Interaction

EMLA should not be used with other topical preparations or medications that may affect the skin.

Drug Interaction

EMLA should not be used with sedatives or anxiety drugs, such as alprazolam (Xanax) or lorazepam (Ativan). It may interact with other medications that can cause drowsiness, such as opioid pain relievers or antidepressants.

Food Interactions

No food interactions have been reported.

Pregnancy Use

Lidocaine and Prilocaine have not been studied during pregnancy and should be used with caution in pregnant women.

Lactation Use

EMLA has not been evaluated in lactating women and should be used with caution.

Acute Overdose

In cases of overdose, supportive measures, including airway support, should be instituted immediately. Activated charcoal may be administered. Hemodialysis is not likely to be beneficial in removing Lidocaine and Prilocaine as they are highly bound to plasma proteins.

Contraindication

EMLA should not be used in patients who are sensitive to any of its components, or have open wounds, cuts, scrapes, or sores near the site of application. It should also not be used in areas affected by frostbite and should be avoided in infants and premature babies.

Use Direction

EMLA should be applied to the affected area once or twice daily, as directed by your doctor. Cover the area with a bandage or plastic wrap after applying.

Storage Conditions

Store at room temperature between 15-30°C. Do not freeze.

Volume of Distribution

The volume of distribution of Lidocaine and Prilocaine is approximately 2.3L/kg.

Half Life

The half-life of Lidocaine and Prilocaine is approximately 2.2 hours.

Clearance

The clearance of Lidocaine and Prilocaine is approximately 0.55L/kg/h.

Here you find in details version of Xylone Plus

Some Frequently Asked Questions About Xylone Plus

What is Lidocaine and Prilocaine?

Lidocaine and Prilocaine are topical anesthetics used to reduce skin sensation to stimulate pain relief before superficial medical treatments.

What is Xylone Plus?

Xylone Plus is a combination of the two topical anesthetics Lidocaine and Prilocaine, which work together to provide a more effective solution for pain relief.

How do Xylone Plus work?

Xylone Plus work by blocking pain signals from reaching the brain, thus allowing for increased numbing of the area. The combination provides additional pain relief compared to a single anesthetic.

What is Xylone Plus used for?

Xylone Plus is most commonly used to provide topical anesthesia prior to minor medical procedures such as laser hair removal, dermabrasion, and surface wound repairs.

Is Xylone Plus safe to use?

Xylone Plus is generally safe to use, though some people may experience minor side effects depending on their individual sensitivity. If any discomfort or adverse reactions occur, stop using the product and contact a medical professional.

What are the side effects of Xylone Plus?

Side effects of Xylone Plus may include skin irritation, redness, swelling, burning, itching, or numbness. If any of these side effects occur, stop using the product and contact a medical professional.

Can I use Xylone Plus while pregnant?

It is not recommended to use Xylone Plus while pregnant. Consult with your physician before using any topical anesthetics during pregnancy.

Where can I purchase Xylone Plus?

You can purchase Xylone Plus from most major retailers as well as online. Make sure to consult your doctor before using any topical anesthetics.

How should Xylone Plus be applied?

Xylone Plus should be applied as directed by the manufacturer or as directed by your doctor. Make sure to carefully follow instructions to ensure safe and effective use.

How long does Xylone Plus last?

The effects of Xylone Plus typically last anywhere from 1 to 2 hours, but the exact duration of action will depend on the individual and the type of procedure being performed.

How long does it take for Xylone Plus to take effect?

The effects of Xylone Plus usually begin to take effect within 10-15 minutes after being applied.

Do I need a prescription for Xylone Plus?

No, a prescription is not necessary in order to purchase Xylone Plus.

What should I do if I accidentally get Xylone Plus in my eyes?

If Xylone Plus is accidentally applied in the eye, rinse out the eye with cool water and contact a doctor immediately.

What should I do if I have an allergic reaction to Xylone Plus?

If you are experiencing an allergic reaction to Xylone Plus, immediately discontinue use and seek medical attention.

Can I use Xylone Plus on open wounds?

No, it is not recommended to use Xylone Plus on open wounds. Consult your doctor to find a suitable anesthetic for open-wound procedures.

Can I use Xylone Plus on children?

It is not recommended to use Xylone Plus on children. If a topical anesthetic is necessary for medical procedures, consult your doctor for an appropriate alternative for children.

Does Xylone Plus cause scarring?

No, Xylone Plus is not known to cause scarring. However, some medical procedures may cause scarring regardless of anesthetic used.

Can I use Xylone Plus on my pets?

No, Xylone Plus is intended for use in humans only and should not be used on pets.

Does Xylone Plus enter the bloodstream?

Yes, Xylone Plus can enter the bloodstream, though this is typically only possible with prolonged use or overapplication of the product.

Is it safe to use Xylone Plus on broken skin?

No, it is not recommended to use Xylone Plus on broken or damaged skin.

Does Xylone Plus work on tattoos?

No, Xylone Plus is not intended for use on tattoos or permanent makeup.

Should I avoid certain activities after using Xylone Plus?

Yes, it is important to avoid activities that require alertness as Xylone Plus can cause some dizziness and drowsiness.

Can I use Xylone Plus long term?

No, it is not recommended to use Xylone Plus long term or on a frequent basis.

Should I wash off Xylone Plus after the procedure?

Yes, it is recommended to wash off any remaining Xylone Plus after the procedure is completed.

Is Xylone Plus type of numbing cream?

Yes, Xylone Plus is a type of topical anesthetic, which causes numbness and helps to reduce pain prior to superficial medical treatments.

What is the difference between Lidocaine and Xylone Plus?

The difference between Lidocaine and Xylone Plus is that Xylone Plus uses a combination of two topical anesthetics, which work together to provide a more effective solution for pain relief.

Can Xylone Plus make the skin numb?

Yes, Xylone Plus can make the skin numb, as it is a topical anesthetic.

Can I use Xylone Plus to treat a sunburn?

No, it is not recommended to use Xylone Plus to treat a sunburn as it is intended for use prior to superficial medical treatments.

Can I use Xylone Plus on cuts and scrapes?

No, it is not recommended to use Xylone Plus on cuts and scrapes as it is intended for use prior to superficial medical treatments. Consult your doctor for an appropriate alternative.

What is the recommended dosage of Xylone Plus?

The recommended dosage of Xylone Plus will depend on individual and the type of procedure being performed. Consult with your doctor for the most appropriate dosage.

Can I use Xylone Plus on my face?

Yes, Xylone Plus can be used on the face, though it should be used as directed by the manufacturer or as directed by your doctor.

Can I use Xylone Plus while breastfeeding?

It is not recommended to use Xylone Plus while breastfeeding. Consult with your physician before using any topical anesthetics while breastfeeding.

Can I use Xylone Plus before getting a tattoo?

No, it is not recommended to use Xylone Plus before getting a tattoo, as it is intended for use prior to superficial medical treatments. Consult your doctor for an appropriate alternative.

Can I use Xylone Plus for other medical procedures?

Yes, Xylone Plus can be used for other medical procedures, though it is important to consult your doctor before using a topical anesthetic for any medical procedure.

When should I stop using Xylone Plus?

It is recommended to stop using Xylone Plus when the procedure is finished and any necessary numbing has occurred. Make sure to follow manufacturer instructions when using the product.

Can I use Xylone Plus after a laser hair removal treatment?

Yes, Xylone Plus is commonly used prior to laser hair removal treatments. Make sure to follow manufacturer instructions when using the product.

Can I use Xylone Plus for oral procedures?

No, it is not recommended to use Xylone Plus for oral procedures. Consult your doctor for an appropriate alternative.

Can I use Xylone Plus on body piercings?

No, it is not recommended to use Xylone Plus on body piercings. Consult your doctor for an appropriate alternative.

Does Xylone Plus interfere with other medications?

Yes, Xylone Plus may interact with certain medications. Before using the product, consult with your doctor about possible interactions with other medications.

Does Xylone Plus have any long term effects?

No, Xylone Plus is not known to have any long term effects. However, using the product on a frequent or long-term basis could lead to sensitization of the skin.

Can I use Xylone Plus after waxing?

Yes, Xylone Plus is commonly used prior to waxing treatments. Make sure to follow manufacturer instructions when using the product.