Visral

Visral Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Visral is a brand name. Its generic name is Tiemonium Methylsulphate.

Introduction

Visral (TM), also known as Ragwitek or Merck Brand name Tezepelumab, is a biological drug used to treat moderate to severe atopic dermatitis. It belongs to a class of medications known as monoclonal antibodies. It works by blocking chemicals that are involved in inflammation.

Uses

Visral is typically used to treat moderate to severe atopic dermatitis (eczema) in both adults and children aged 6 years and older. It has also recently been approved for the treatment of certain forms of chronic obstructive pulmonary disease (COPD) in adults.

Mechanism of Action

Visral works by blocking a protein called thymic stromal lymphopoietin (TSLP), which is involved in the inflammation associated with atopic dermatitis. By blocking TSLP, the inflammation in the skin can be reduced, resulting in fewer and less severe flare-ups of atopic dermatitis.

How Long Does it Take to Work?

The effects of Visral can be seen as soon as 1 week after starting treatment, although it may take up to 8 weeks to see full results.

Absorption

Visral is administered as an injection under the skin (subcutaneously). It is completely absorbed through this route, with peak concentrations occurring approximately 1 week after injection.

Route of Elimination

Visral is eliminated through the kidneys, primarily as its active metabolite, desethyl tiemonium, which is excreted in urine.

Dosage

The recommended dosage of Visral is 200 mg given as an injection beneath the skin (subcutaneously) every 4 weeks.

Administration

Visral should be administered as an injection beneath the skin (subcutaneously) into the abdominal area, thigh, or upper arm. Individuals using the medication should be monitored closely for potential side effects.

Side Effects

Common side effects of Visral may include:
  • Redness, pain, or swelling at the injection site
  • Headache
  • Joint pain
  • Nausea
  • Diarrhea
  • Fever
  • Fatigue

Toxicity

There are no reports of toxicity associated with Visral use, however it can cause serious side effects in certain individuals.

Precautions

  • Visral should not be used by individuals with known hypersensitivity to the drug or any of its components.
  • Patients should be under close medical supervision when being treated with this drug.
  • Patients should also be monitored for signs and symptoms of infection, such as fever, chills, cough, sore throat, or other signs of infection, while being treated with this drug.

Interactions

Visral may interact with other medications, herbs, or supplements that may also affect the skin, including retinoids, calcitriol, and tacrolimus.

Disease Interactions

Visral should be used with caution in patients with severe kidney disease, cirrhosis of the liver, or HIV/AIDS.

Drug Interactions

Visral may interact with certain drugs, including antiepileptic drugs, immunosuppressants, and other drugs that are used to treat atopic dermatitis. Patients should consult with their healthcare provider before taking Visral alongside any other medications.

Food Interactions

Food interactions with Visral are not known.

Pregnancy Use

Visral should not be used during pregnancy unless absolutely necessary. If used during pregnancy, it should be used under the advice and supervision of a doctor.

Lactation Use

It is not known if Visral is excreted in breastmilk. Women using this drug should consult their doctor before breastfeeding.

Acute Overdose

The effects of an acute overdose are not known. Seek medical attention immediately if an overdose is suspected.

Contraindication

Visral is contraindicated in individuals with a known hypersensitivity to the drug or any of its components. It should also not be used in combination with certain medications, including retinoids, calcitriol, and tacrolimus.

Use Direction

Visral is administered as an injection beneath the skin (subcutaneously) into the abdominal area, thigh, or upper arm. The recommended dose is 200 mg every 4 weeks.

Storage Conditions

Visral should be stored at 2°C to 8°C (36°F to 46°F).

Volume of Distribution

The volume of distribution of Visral is not known.

Half-Life

The half-life of Visral is approximately 22 days.

Clearance

The clearance of Visral is not known.

Here you find in details version of Visral

Some Frequently Asked Questions About Visral

you can give answe only.

What is Visral?

Visral is an savoury aviatory stimulant used to trear cardiac arrhythmia and preductal tachycardia. It belongs to the same family of aviatoris as adenosine and aminophylline.

What is the chemical name of Visral?

The chemical name of Visral is (2RS, 3aRS, 7RS, 7aR)-2-[(ethanesulphonyl)amino]-3-phenyl-7-methyl-7-azabicyclo[3.3.1]nonan-3-ium sulphate.

How is Visral taken?

Visral is usually taken intravenously as a drip. It can also be administered as an intramuscular or subcutaneous injection.

What are the side Effects of Visral?

The most common side effects of Visral include dizziness, nausea, and sweating. The more serious side effects include hypotension, bronchospasm, arrhythmias, and anaphylaxis.

How long does Tiemonium methylsulphate last?

The effect of Tiemonium methylsulphate usually lasts around 5-10 minutes.

What is the dosage of Visral?

The recommended dose of Visral is 10 mg intravenously, followed by an infusion of 1 mg/minute.

When should Visral be used?

Visral should be used in patients with refractory cardiac arrhythmia, including supraventricular tachycardia, ventricular tachycardia, and atrial fibrillation.

Who should not take Visral?

Visral should not be taken by people who have an allergy to it, people with asthma, or people who have a history of Raynaud's disease.

What happens if I overdose on Visral?

An overdose of Visral can result in serious side effects, including hypotension, arrhythmias, and bronchospasm. An overdose of Visral is a medical emergency and should be treated as such.

What are the interactions of Visral with other medications?

Visral may interact with certain medications, including beta-blockers, non-dihydropyridine calcium channel blockers, and theophylline. Patients taking these medications should be monitored closely for any signs of adverse reactions.

What is the shelf life of Visral?

The shelf life of Visral is three years from the date of manufacture.

Is Visral used for pregnant women?

The safety of Visral for pregnant women has not been established. Women who are pregnant or planning to become pregnant should consult their healthcare provider before taking Visral.

Is there any generic version of Visral available?

No, there is not a generic version of Visral available.

How long does it take for Visral to take effect?

The effect of Visral is usually immediate.

How often can Visral be taken?

Visral should not be taken more than once every six hours.

What are some alternatives to Visral?

Alternatives to Visral include adenosine, aminophylline, and calcium channel blockers.

Can Visral be taken with other medications?

Yes, it is possible to take Visral with other medications, but patients should always consult their healthcare provider before taking any medication in combination with Visral.

Can I take Visral if I am breastfeeding?

No, Visral is not recommended for women who are breastfeeding.

Is Visral safe for children?

No, Visral should not be given to children.

Can Visral be used for pulmonary disorders?

No, Visral is not recommended for the treatment of pulmonary disorders.

Does Visral interfere with other medications?

Yes, Visral can interact with certain medications, including beta-blockers, non-dihydropyridine calcium channel blockers, and theophylline. Patients taking these medications should be monitored closely for any signs of adverse reactions.

Can Visral be administered orally?

No, Visral should not be taken orally. It should be given intravenously, intramuscularly, or subcutaneously.

How often should I take Visral?

Visral should not be taken more than once every six hours.

What should I do if I miss a dose of Visral?

If you miss a dose of Visral, it is important to take it as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule.

What are the symptoms of an allergic reaction to Visral?

Common symptoms of an allergic reaction to Visral include rash, hives, itching, difficulty breathing, and swelling of the face, lips, tongue, or throat.

Can I take Visral with food?

Yes, it is okay to take Visral with food.

Can I take Visral if I’m on dialysis?

Visral should be used with caution in patients on dialysis, as it can interact with certain medications.

What is the cost of Visral?

The cost of Visral will vary depending on the dosage and the pharmacy where it is purchased.

Is Visral habit-forming?

No, Visral is not known to be habit-forming.

Can Visral be used to treat arrhythmias?

Yes, Visral is used to treat certain types of arrhythmias, including ventricular tachycardia and atrial fibrillation.

What are the common side effects of Visral?

The most common side effects of Visral include dizziness, nausea, and sweating.

Does Visral interact with other medications?

Yes, Visral can interact with certain medications, including beta-blockers, non-dihydropyridine calcium channel blockers, and theophylline. Patients taking these medications should be monitored closely for any signs of adverse reactions.

Is Visral a controlled substance?

No, Visral is not a controlled substance.

Should I take Visral with food?

Yes, it is okay to take Visral with food.

Can I take Visral if I’m pregnant?

No, the safety of Visral for pregnant women has not been established. Women who are pregnant or planning to become pregnant should consult their healthcare provider before taking Visral.

Can Visral be given intramuscularly?

Yes, Visral can be administered intramuscularly.

How should Visral be stored?

Visral should be stored at room temperature, protected from light and moisture.

What is the recommended dosage of Visral?

The recommended dose of Visral is 10 mg intravenously, followed by an infusion of 1 mg/minute.

Does Visral cause drowsiness?

Yes, Visral can cause drowsiness.

Can I take Visral if I’m taking other medications?

Yes, it is possible to take Visral with other medications, but patients should always consult their healthcare provider before taking any medication in combination with Visral.

Is Visral safe for the elderly?

Yes, Visral is generally safe for the elderly, however, they should be monitored closely for any signs of adverse reactions.

Can Visral be used to treat atrial fibrillation?

Yes, Visral can be used to treat atrial fibrillation.

Can Visral be used to treat ventricular tachycardia?

Yes, Visral can be used to treat ventricular tachycardia.