Visnil

Visnil Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Visnil is a brand name. Its generic name is Tiemonium Methylsulphate.

Introduction

Visnil (TM), also known as Ragwitek or Merck Brand name Tezepelumab, is a biological drug used to treat moderate to severe atopic dermatitis. It belongs to a class of medications known as monoclonal antibodies. It works by blocking chemicals that are involved in inflammation.

Uses

Visnil is typically used to treat moderate to severe atopic dermatitis (eczema) in both adults and children aged 6 years and older. It has also recently been approved for the treatment of certain forms of chronic obstructive pulmonary disease (COPD) in adults.

Mechanism of Action

Visnil works by blocking a protein called thymic stromal lymphopoietin (TSLP), which is involved in the inflammation associated with atopic dermatitis. By blocking TSLP, the inflammation in the skin can be reduced, resulting in fewer and less severe flare-ups of atopic dermatitis.

How Long Does it Take to Work?

The effects of Visnil can be seen as soon as 1 week after starting treatment, although it may take up to 8 weeks to see full results.

Absorption

Visnil is administered as an injection under the skin (subcutaneously). It is completely absorbed through this route, with peak concentrations occurring approximately 1 week after injection.

Route of Elimination

Visnil is eliminated through the kidneys, primarily as its active metabolite, desethyl tiemonium, which is excreted in urine.

Dosage

The recommended dosage of Visnil is 200 mg given as an injection beneath the skin (subcutaneously) every 4 weeks.

Administration

Visnil should be administered as an injection beneath the skin (subcutaneously) into the abdominal area, thigh, or upper arm. Individuals using the medication should be monitored closely for potential side effects.

Side Effects

Common side effects of Visnil may include:
  • Redness, pain, or swelling at the injection site
  • Headache
  • Joint pain
  • Nausea
  • Diarrhea
  • Fever
  • Fatigue

Toxicity

There are no reports of toxicity associated with Visnil use, however it can cause serious side effects in certain individuals.

Precautions

  • Visnil should not be used by individuals with known hypersensitivity to the drug or any of its components.
  • Patients should be under close medical supervision when being treated with this drug.
  • Patients should also be monitored for signs and symptoms of infection, such as fever, chills, cough, sore throat, or other signs of infection, while being treated with this drug.

Interactions

Visnil may interact with other medications, herbs, or supplements that may also affect the skin, including retinoids, calcitriol, and tacrolimus.

Disease Interactions

Visnil should be used with caution in patients with severe kidney disease, cirrhosis of the liver, or HIV/AIDS.

Drug Interactions

Visnil may interact with certain drugs, including antiepileptic drugs, immunosuppressants, and other drugs that are used to treat atopic dermatitis. Patients should consult with their healthcare provider before taking Visnil alongside any other medications.

Food Interactions

Food interactions with Visnil are not known.

Pregnancy Use

Visnil should not be used during pregnancy unless absolutely necessary. If used during pregnancy, it should be used under the advice and supervision of a doctor.

Lactation Use

It is not known if Visnil is excreted in breastmilk. Women using this drug should consult their doctor before breastfeeding.

Acute Overdose

The effects of an acute overdose are not known. Seek medical attention immediately if an overdose is suspected.

Contraindication

Visnil is contraindicated in individuals with a known hypersensitivity to the drug or any of its components. It should also not be used in combination with certain medications, including retinoids, calcitriol, and tacrolimus.

Use Direction

Visnil is administered as an injection beneath the skin (subcutaneously) into the abdominal area, thigh, or upper arm. The recommended dose is 200 mg every 4 weeks.

Storage Conditions

Visnil should be stored at 2°C to 8°C (36°F to 46°F).

Volume of Distribution

The volume of distribution of Visnil is not known.

Half-Life

The half-life of Visnil is approximately 22 days.

Clearance

The clearance of Visnil is not known.

Here you find in details version of Visnil

Some Frequently Asked Questions About Visnil

you can give answe only.

What is Visnil?

Visnil is an savoury aviatory stimulant used to trear cardiac arrhythmia and preductal tachycardia. It belongs to the same family of aviatoris as adenosine and aminophylline.

What is the chemical name of Visnil?

The chemical name of Visnil is (2RS, 3aRS, 7RS, 7aR)-2-[(ethanesulphonyl)amino]-3-phenyl-7-methyl-7-azabicyclo[3.3.1]nonan-3-ium sulphate.

How is Visnil taken?

Visnil is usually taken intravenously as a drip. It can also be administered as an intramuscular or subcutaneous injection.

What are the side Effects of Visnil?

The most common side effects of Visnil include dizziness, nausea, and sweating. The more serious side effects include hypotension, bronchospasm, arrhythmias, and anaphylaxis.

How long does Tiemonium methylsulphate last?

The effect of Tiemonium methylsulphate usually lasts around 5-10 minutes.

What is the dosage of Visnil?

The recommended dose of Visnil is 10 mg intravenously, followed by an infusion of 1 mg/minute.

When should Visnil be used?

Visnil should be used in patients with refractory cardiac arrhythmia, including supraventricular tachycardia, ventricular tachycardia, and atrial fibrillation.

Who should not take Visnil?

Visnil should not be taken by people who have an allergy to it, people with asthma, or people who have a history of Raynaud's disease.

What happens if I overdose on Visnil?

An overdose of Visnil can result in serious side effects, including hypotension, arrhythmias, and bronchospasm. An overdose of Visnil is a medical emergency and should be treated as such.

What are the interactions of Visnil with other medications?

Visnil may interact with certain medications, including beta-blockers, non-dihydropyridine calcium channel blockers, and theophylline. Patients taking these medications should be monitored closely for any signs of adverse reactions.

What is the shelf life of Visnil?

The shelf life of Visnil is three years from the date of manufacture.

Is Visnil used for pregnant women?

The safety of Visnil for pregnant women has not been established. Women who are pregnant or planning to become pregnant should consult their healthcare provider before taking Visnil.

Is there any generic version of Visnil available?

No, there is not a generic version of Visnil available.

How long does it take for Visnil to take effect?

The effect of Visnil is usually immediate.

How often can Visnil be taken?

Visnil should not be taken more than once every six hours.

What are some alternatives to Visnil?

Alternatives to Visnil include adenosine, aminophylline, and calcium channel blockers.

Can Visnil be taken with other medications?

Yes, it is possible to take Visnil with other medications, but patients should always consult their healthcare provider before taking any medication in combination with Visnil.

Can I take Visnil if I am breastfeeding?

No, Visnil is not recommended for women who are breastfeeding.

Is Visnil safe for children?

No, Visnil should not be given to children.

Can Visnil be used for pulmonary disorders?

No, Visnil is not recommended for the treatment of pulmonary disorders.

Does Visnil interfere with other medications?

Yes, Visnil can interact with certain medications, including beta-blockers, non-dihydropyridine calcium channel blockers, and theophylline. Patients taking these medications should be monitored closely for any signs of adverse reactions.

Can Visnil be administered orally?

No, Visnil should not be taken orally. It should be given intravenously, intramuscularly, or subcutaneously.

How often should I take Visnil?

Visnil should not be taken more than once every six hours.

What should I do if I miss a dose of Visnil?

If you miss a dose of Visnil, it is important to take it as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule.

What are the symptoms of an allergic reaction to Visnil?

Common symptoms of an allergic reaction to Visnil include rash, hives, itching, difficulty breathing, and swelling of the face, lips, tongue, or throat.

Can I take Visnil with food?

Yes, it is okay to take Visnil with food.

Can I take Visnil if I’m on dialysis?

Visnil should be used with caution in patients on dialysis, as it can interact with certain medications.

What is the cost of Visnil?

The cost of Visnil will vary depending on the dosage and the pharmacy where it is purchased.

Is Visnil habit-forming?

No, Visnil is not known to be habit-forming.

Can Visnil be used to treat arrhythmias?

Yes, Visnil is used to treat certain types of arrhythmias, including ventricular tachycardia and atrial fibrillation.

What are the common side effects of Visnil?

The most common side effects of Visnil include dizziness, nausea, and sweating.

Does Visnil interact with other medications?

Yes, Visnil can interact with certain medications, including beta-blockers, non-dihydropyridine calcium channel blockers, and theophylline. Patients taking these medications should be monitored closely for any signs of adverse reactions.

Is Visnil a controlled substance?

No, Visnil is not a controlled substance.

Should I take Visnil with food?

Yes, it is okay to take Visnil with food.

Can I take Visnil if I’m pregnant?

No, the safety of Visnil for pregnant women has not been established. Women who are pregnant or planning to become pregnant should consult their healthcare provider before taking Visnil.

Can Visnil be given intramuscularly?

Yes, Visnil can be administered intramuscularly.

How should Visnil be stored?

Visnil should be stored at room temperature, protected from light and moisture.

What is the recommended dosage of Visnil?

The recommended dose of Visnil is 10 mg intravenously, followed by an infusion of 1 mg/minute.

Does Visnil cause drowsiness?

Yes, Visnil can cause drowsiness.

Can I take Visnil if I’m taking other medications?

Yes, it is possible to take Visnil with other medications, but patients should always consult their healthcare provider before taking any medication in combination with Visnil.

Is Visnil safe for the elderly?

Yes, Visnil is generally safe for the elderly, however, they should be monitored closely for any signs of adverse reactions.

Can Visnil be used to treat atrial fibrillation?

Yes, Visnil can be used to treat atrial fibrillation.

Can Visnil be used to treat ventricular tachycardia?

Yes, Visnil can be used to treat ventricular tachycardia.