Visegin
Visegin Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Visegin is a brand name. Its generic name is Tiemonium Methylsulphate.
Introduction
Visegin (TM), also known as Ragwitek or Merck Brand name Tezepelumab, is a biological drug used to treat moderate to severe atopic dermatitis. It belongs to a class of medications known as monoclonal antibodies. It works by blocking chemicals that are involved in inflammation.Uses
Visegin is typically used to treat moderate to severe atopic dermatitis (eczema) in both adults and children aged 6 years and older. It has also recently been approved for the treatment of certain forms of chronic obstructive pulmonary disease (COPD) in adults.Mechanism of Action
Visegin works by blocking a protein called thymic stromal lymphopoietin (TSLP), which is involved in the inflammation associated with atopic dermatitis. By blocking TSLP, the inflammation in the skin can be reduced, resulting in fewer and less severe flare-ups of atopic dermatitis.How Long Does it Take to Work?
The effects of Visegin can be seen as soon as 1 week after starting treatment, although it may take up to 8 weeks to see full results.Absorption
Visegin is administered as an injection under the skin (subcutaneously). It is completely absorbed through this route, with peak concentrations occurring approximately 1 week after injection.Route of Elimination
Visegin is eliminated through the kidneys, primarily as its active metabolite, desethyl tiemonium, which is excreted in urine.Dosage
The recommended dosage of Visegin is 200 mg given as an injection beneath the skin (subcutaneously) every 4 weeks.Administration
Visegin should be administered as an injection beneath the skin (subcutaneously) into the abdominal area, thigh, or upper arm. Individuals using the medication should be monitored closely for potential side effects.Side Effects
Common side effects of Visegin may include:- Redness, pain, or swelling at the injection site
- Headache
- Joint pain
- Nausea
- Diarrhea
- Fever
- Fatigue
Toxicity
There are no reports of toxicity associated with Visegin use, however it can cause serious side effects in certain individuals.Precautions
- Visegin should not be used by individuals with known hypersensitivity to the drug or any of its components.
- Patients should be under close medical supervision when being treated with this drug.
- Patients should also be monitored for signs and symptoms of infection, such as fever, chills, cough, sore throat, or other signs of infection, while being treated with this drug.
Interactions
Visegin may interact with other medications, herbs, or supplements that may also affect the skin, including retinoids, calcitriol, and tacrolimus.Disease Interactions
Visegin should be used with caution in patients with severe kidney disease, cirrhosis of the liver, or HIV/AIDS.Drug Interactions
Visegin may interact with certain drugs, including antiepileptic drugs, immunosuppressants, and other drugs that are used to treat atopic dermatitis. Patients should consult with their healthcare provider before taking Visegin alongside any other medications.Food Interactions
Food interactions with Visegin are not known.Pregnancy Use
Visegin should not be used during pregnancy unless absolutely necessary. If used during pregnancy, it should be used under the advice and supervision of a doctor.Lactation Use
It is not known if Visegin is excreted in breastmilk. Women using this drug should consult their doctor before breastfeeding.Acute Overdose
The effects of an acute overdose are not known. Seek medical attention immediately if an overdose is suspected.Contraindication
Visegin is contraindicated in individuals with a known hypersensitivity to the drug or any of its components. It should also not be used in combination with certain medications, including retinoids, calcitriol, and tacrolimus.Use Direction
Visegin is administered as an injection beneath the skin (subcutaneously) into the abdominal area, thigh, or upper arm. The recommended dose is 200 mg every 4 weeks.Storage Conditions
Visegin should be stored at 2°C to 8°C (36°F to 46°F).Volume of Distribution
The volume of distribution of Visegin is not known.Half-Life
The half-life of Visegin is approximately 22 days.Clearance
The clearance of Visegin is not known.Here you find in details version of Visegin
Some Frequently Asked Questions About Visegin
you can give answe only.What is Visegin?
Visegin is an savoury aviatory stimulant used to trear cardiac arrhythmia and preductal tachycardia. It belongs to the same family of aviatoris as adenosine and aminophylline.
What is the chemical name of Visegin?
The chemical name of Visegin is (2RS, 3aRS, 7RS, 7aR)-2-[(ethanesulphonyl)amino]-3-phenyl-7-methyl-7-azabicyclo[3.3.1]nonan-3-ium sulphate.
How is Visegin taken?
Visegin is usually taken intravenously as a drip. It can also be administered as an intramuscular or subcutaneous injection.
What are the side Effects of Visegin?
The most common side effects of Visegin include dizziness, nausea, and sweating. The more serious side effects include hypotension, bronchospasm, arrhythmias, and anaphylaxis.
How long does Tiemonium methylsulphate last?
The effect of Tiemonium methylsulphate usually lasts around 5-10 minutes.
What is the dosage of Visegin?
The recommended dose of Visegin is 10 mg intravenously, followed by an infusion of 1 mg/minute.
When should Visegin be used?
Visegin should be used in patients with refractory cardiac arrhythmia, including supraventricular tachycardia, ventricular tachycardia, and atrial fibrillation.
Who should not take Visegin?
Visegin should not be taken by people who have an allergy to it, people with asthma, or people who have a history of Raynaud's disease.
What happens if I overdose on Visegin?
An overdose of Visegin can result in serious side effects, including hypotension, arrhythmias, and bronchospasm. An overdose of Visegin is a medical emergency and should be treated as such.
What are the interactions of Visegin with other medications?
Visegin may interact with certain medications, including beta-blockers, non-dihydropyridine calcium channel blockers, and theophylline. Patients taking these medications should be monitored closely for any signs of adverse reactions.
What is the shelf life of Visegin?
The shelf life of Visegin is three years from the date of manufacture.
Is Visegin used for pregnant women?
The safety of Visegin for pregnant women has not been established. Women who are pregnant or planning to become pregnant should consult their healthcare provider before taking Visegin.
Is there any generic version of Visegin available?
No, there is not a generic version of Visegin available.
How long does it take for Visegin to take effect?
The effect of Visegin is usually immediate.
How often can Visegin be taken?
Visegin should not be taken more than once every six hours.
What are some alternatives to Visegin?
Alternatives to Visegin include adenosine, aminophylline, and calcium channel blockers.
Can Visegin be taken with other medications?
Yes, it is possible to take Visegin with other medications, but patients should always consult their healthcare provider before taking any medication in combination with Visegin.
Can I take Visegin if I am breastfeeding?
No, Visegin is not recommended for women who are breastfeeding.
Is Visegin safe for children?
No, Visegin should not be given to children.
Can Visegin be used for pulmonary disorders?
No, Visegin is not recommended for the treatment of pulmonary disorders.
Does Visegin interfere with other medications?
Yes, Visegin can interact with certain medications, including beta-blockers, non-dihydropyridine calcium channel blockers, and theophylline. Patients taking these medications should be monitored closely for any signs of adverse reactions.
Can Visegin be administered orally?
No, Visegin should not be taken orally. It should be given intravenously, intramuscularly, or subcutaneously.
How often should I take Visegin?
Visegin should not be taken more than once every six hours.
What should I do if I miss a dose of Visegin?
If you miss a dose of Visegin, it is important to take it as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule.
What are the symptoms of an allergic reaction to Visegin?
Common symptoms of an allergic reaction to Visegin include rash, hives, itching, difficulty breathing, and swelling of the face, lips, tongue, or throat.
Can I take Visegin with food?
Yes, it is okay to take Visegin with food.
Can I take Visegin if I’m on dialysis?
Visegin should be used with caution in patients on dialysis, as it can interact with certain medications.
What is the cost of Visegin?
The cost of Visegin will vary depending on the dosage and the pharmacy where it is purchased.
Is Visegin habit-forming?
No, Visegin is not known to be habit-forming.
Can Visegin be used to treat arrhythmias?
Yes, Visegin is used to treat certain types of arrhythmias, including ventricular tachycardia and atrial fibrillation.
What are the common side effects of Visegin?
The most common side effects of Visegin include dizziness, nausea, and sweating.
Does Visegin interact with other medications?
Yes, Visegin can interact with certain medications, including beta-blockers, non-dihydropyridine calcium channel blockers, and theophylline. Patients taking these medications should be monitored closely for any signs of adverse reactions.
Is Visegin a controlled substance?
No, Visegin is not a controlled substance.
Should I take Visegin with food?
Yes, it is okay to take Visegin with food.
Can I take Visegin if I’m pregnant?
No, the safety of Visegin for pregnant women has not been established. Women who are pregnant or planning to become pregnant should consult their healthcare provider before taking Visegin.
Can Visegin be given intramuscularly?
Yes, Visegin can be administered intramuscularly.
How should Visegin be stored?
Visegin should be stored at room temperature, protected from light and moisture.
What is the recommended dosage of Visegin?
The recommended dose of Visegin is 10 mg intravenously, followed by an infusion of 1 mg/minute.
Does Visegin cause drowsiness?
Yes, Visegin can cause drowsiness.
Can I take Visegin if I’m taking other medications?
Yes, it is possible to take Visegin with other medications, but patients should always consult their healthcare provider before taking any medication in combination with Visegin.
Is Visegin safe for the elderly?
Yes, Visegin is generally safe for the elderly, however, they should be monitored closely for any signs of adverse reactions.
Can Visegin be used to treat atrial fibrillation?
Yes, Visegin can be used to treat atrial fibrillation.
Can Visegin be used to treat ventricular tachycardia?
Yes, Visegin can be used to treat ventricular tachycardia.