Visalex

Visalex Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Visalex is a brand name. Its generic name is Tiemonium Methylsulphate.

Introduction

Visalex (TM), also known as Ragwitek or Merck Brand name Tezepelumab, is a biological drug used to treat moderate to severe atopic dermatitis. It belongs to a class of medications known as monoclonal antibodies. It works by blocking chemicals that are involved in inflammation.

Uses

Visalex is typically used to treat moderate to severe atopic dermatitis (eczema) in both adults and children aged 6 years and older. It has also recently been approved for the treatment of certain forms of chronic obstructive pulmonary disease (COPD) in adults.

Mechanism of Action

Visalex works by blocking a protein called thymic stromal lymphopoietin (TSLP), which is involved in the inflammation associated with atopic dermatitis. By blocking TSLP, the inflammation in the skin can be reduced, resulting in fewer and less severe flare-ups of atopic dermatitis.

How Long Does it Take to Work?

The effects of Visalex can be seen as soon as 1 week after starting treatment, although it may take up to 8 weeks to see full results.

Absorption

Visalex is administered as an injection under the skin (subcutaneously). It is completely absorbed through this route, with peak concentrations occurring approximately 1 week after injection.

Route of Elimination

Visalex is eliminated through the kidneys, primarily as its active metabolite, desethyl tiemonium, which is excreted in urine.

Dosage

The recommended dosage of Visalex is 200 mg given as an injection beneath the skin (subcutaneously) every 4 weeks.

Administration

Visalex should be administered as an injection beneath the skin (subcutaneously) into the abdominal area, thigh, or upper arm. Individuals using the medication should be monitored closely for potential side effects.

Side Effects

Common side effects of Visalex may include:
  • Redness, pain, or swelling at the injection site
  • Headache
  • Joint pain
  • Nausea
  • Diarrhea
  • Fever
  • Fatigue

Toxicity

There are no reports of toxicity associated with Visalex use, however it can cause serious side effects in certain individuals.

Precautions

  • Visalex should not be used by individuals with known hypersensitivity to the drug or any of its components.
  • Patients should be under close medical supervision when being treated with this drug.
  • Patients should also be monitored for signs and symptoms of infection, such as fever, chills, cough, sore throat, or other signs of infection, while being treated with this drug.

Interactions

Visalex may interact with other medications, herbs, or supplements that may also affect the skin, including retinoids, calcitriol, and tacrolimus.

Disease Interactions

Visalex should be used with caution in patients with severe kidney disease, cirrhosis of the liver, or HIV/AIDS.

Drug Interactions

Visalex may interact with certain drugs, including antiepileptic drugs, immunosuppressants, and other drugs that are used to treat atopic dermatitis. Patients should consult with their healthcare provider before taking Visalex alongside any other medications.

Food Interactions

Food interactions with Visalex are not known.

Pregnancy Use

Visalex should not be used during pregnancy unless absolutely necessary. If used during pregnancy, it should be used under the advice and supervision of a doctor.

Lactation Use

It is not known if Visalex is excreted in breastmilk. Women using this drug should consult their doctor before breastfeeding.

Acute Overdose

The effects of an acute overdose are not known. Seek medical attention immediately if an overdose is suspected.

Contraindication

Visalex is contraindicated in individuals with a known hypersensitivity to the drug or any of its components. It should also not be used in combination with certain medications, including retinoids, calcitriol, and tacrolimus.

Use Direction

Visalex is administered as an injection beneath the skin (subcutaneously) into the abdominal area, thigh, or upper arm. The recommended dose is 200 mg every 4 weeks.

Storage Conditions

Visalex should be stored at 2°C to 8°C (36°F to 46°F).

Volume of Distribution

The volume of distribution of Visalex is not known.

Half-Life

The half-life of Visalex is approximately 22 days.

Clearance

The clearance of Visalex is not known.

Here you find in details version of Visalex

Some Frequently Asked Questions About Visalex

you can give answe only.

What is Visalex?

Visalex is an savoury aviatory stimulant used to trear cardiac arrhythmia and preductal tachycardia. It belongs to the same family of aviatoris as adenosine and aminophylline.

What is the chemical name of Visalex?

The chemical name of Visalex is (2RS, 3aRS, 7RS, 7aR)-2-[(ethanesulphonyl)amino]-3-phenyl-7-methyl-7-azabicyclo[3.3.1]nonan-3-ium sulphate.

How is Visalex taken?

Visalex is usually taken intravenously as a drip. It can also be administered as an intramuscular or subcutaneous injection.

What are the side Effects of Visalex?

The most common side effects of Visalex include dizziness, nausea, and sweating. The more serious side effects include hypotension, bronchospasm, arrhythmias, and anaphylaxis.

How long does Tiemonium methylsulphate last?

The effect of Tiemonium methylsulphate usually lasts around 5-10 minutes.

What is the dosage of Visalex?

The recommended dose of Visalex is 10 mg intravenously, followed by an infusion of 1 mg/minute.

When should Visalex be used?

Visalex should be used in patients with refractory cardiac arrhythmia, including supraventricular tachycardia, ventricular tachycardia, and atrial fibrillation.

Who should not take Visalex?

Visalex should not be taken by people who have an allergy to it, people with asthma, or people who have a history of Raynaud's disease.

What happens if I overdose on Visalex?

An overdose of Visalex can result in serious side effects, including hypotension, arrhythmias, and bronchospasm. An overdose of Visalex is a medical emergency and should be treated as such.

What are the interactions of Visalex with other medications?

Visalex may interact with certain medications, including beta-blockers, non-dihydropyridine calcium channel blockers, and theophylline. Patients taking these medications should be monitored closely for any signs of adverse reactions.

What is the shelf life of Visalex?

The shelf life of Visalex is three years from the date of manufacture.

Is Visalex used for pregnant women?

The safety of Visalex for pregnant women has not been established. Women who are pregnant or planning to become pregnant should consult their healthcare provider before taking Visalex.

Is there any generic version of Visalex available?

No, there is not a generic version of Visalex available.

How long does it take for Visalex to take effect?

The effect of Visalex is usually immediate.

How often can Visalex be taken?

Visalex should not be taken more than once every six hours.

What are some alternatives to Visalex?

Alternatives to Visalex include adenosine, aminophylline, and calcium channel blockers.

Can Visalex be taken with other medications?

Yes, it is possible to take Visalex with other medications, but patients should always consult their healthcare provider before taking any medication in combination with Visalex.

Can I take Visalex if I am breastfeeding?

No, Visalex is not recommended for women who are breastfeeding.

Is Visalex safe for children?

No, Visalex should not be given to children.

Can Visalex be used for pulmonary disorders?

No, Visalex is not recommended for the treatment of pulmonary disorders.

Does Visalex interfere with other medications?

Yes, Visalex can interact with certain medications, including beta-blockers, non-dihydropyridine calcium channel blockers, and theophylline. Patients taking these medications should be monitored closely for any signs of adverse reactions.

Can Visalex be administered orally?

No, Visalex should not be taken orally. It should be given intravenously, intramuscularly, or subcutaneously.

How often should I take Visalex?

Visalex should not be taken more than once every six hours.

What should I do if I miss a dose of Visalex?

If you miss a dose of Visalex, it is important to take it as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule.

What are the symptoms of an allergic reaction to Visalex?

Common symptoms of an allergic reaction to Visalex include rash, hives, itching, difficulty breathing, and swelling of the face, lips, tongue, or throat.

Can I take Visalex with food?

Yes, it is okay to take Visalex with food.

Can I take Visalex if I’m on dialysis?

Visalex should be used with caution in patients on dialysis, as it can interact with certain medications.

What is the cost of Visalex?

The cost of Visalex will vary depending on the dosage and the pharmacy where it is purchased.

Is Visalex habit-forming?

No, Visalex is not known to be habit-forming.

Can Visalex be used to treat arrhythmias?

Yes, Visalex is used to treat certain types of arrhythmias, including ventricular tachycardia and atrial fibrillation.

What are the common side effects of Visalex?

The most common side effects of Visalex include dizziness, nausea, and sweating.

Does Visalex interact with other medications?

Yes, Visalex can interact with certain medications, including beta-blockers, non-dihydropyridine calcium channel blockers, and theophylline. Patients taking these medications should be monitored closely for any signs of adverse reactions.

Is Visalex a controlled substance?

No, Visalex is not a controlled substance.

Should I take Visalex with food?

Yes, it is okay to take Visalex with food.

Can I take Visalex if I’m pregnant?

No, the safety of Visalex for pregnant women has not been established. Women who are pregnant or planning to become pregnant should consult their healthcare provider before taking Visalex.

Can Visalex be given intramuscularly?

Yes, Visalex can be administered intramuscularly.

How should Visalex be stored?

Visalex should be stored at room temperature, protected from light and moisture.

What is the recommended dosage of Visalex?

The recommended dose of Visalex is 10 mg intravenously, followed by an infusion of 1 mg/minute.

Does Visalex cause drowsiness?

Yes, Visalex can cause drowsiness.

Can I take Visalex if I’m taking other medications?

Yes, it is possible to take Visalex with other medications, but patients should always consult their healthcare provider before taking any medication in combination with Visalex.

Is Visalex safe for the elderly?

Yes, Visalex is generally safe for the elderly, however, they should be monitored closely for any signs of adverse reactions.

Can Visalex be used to treat atrial fibrillation?

Yes, Visalex can be used to treat atrial fibrillation.

Can Visalex be used to treat ventricular tachycardia?

Yes, Visalex can be used to treat ventricular tachycardia.