Viglimet

Viglimet Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Viglimet is a brand name. Its generic name is Vildagliptin + Metformin.

Introduction

Vildagliptin and Metformin is a combination medicine used to improve glycemic control (blood sugar) in patients with type 2 diabetes. It works by decreasing the amount of glucose (sugar) made by the liver and helping the body respond better to insulin. This helps to lower blood sugar levels.

Uses

Vildagliptin and Metformin is used to treat type 2 diabetes. It is meant to lower blood glucose levels in patients who are having difficulty controlling their diabetes with diet, exercise, and other medications.

Mechanism of Action

The combination of Vildagliptin and Metformin has several mechanisms of action. Vildagliptin works by inhibiting an enzyme called DPP-IV (dipeptidyl peptidase-4) which breaks down a hormone called GLP-1 (glucagon-like peptide-1). GLP-1 helps control glucose levels in the body by stimulating the release of insulin from the pancreas. Metformin works by decreasing the production of glucose in the liver and increasing the transport of glucose out of the body's cells.

How Long Does it Take to Work?

The effects of Vildagliptin and Metformin usually starts within one hour and last up to 24 hours. It typically takes one to two weeks to see a noticeable improvement in blood sugar control.

Absorption

Vildagliptin is rapidly and completely absorbed following oral administration. Metformin is slowly absorbed and reaches peak concentrations in 1-2 hours.

Route of Elimination

Vildagliptin is eliminated primarily by the kidneys. Metformin is eliminated through the kidneys, and is primarily excreted unchanged in the urine.

Dosage

The usual starting dose for adults is one 50 mg/850 mg tablet of Vildagliptin and Metformin twice a day. The dose should be taken with a meal. The dose may be increased in increments of 50 mg/500 mg twice daily every two weeks, if needed, up to the maximum recommended dose of two 100 mg/2000 mg tablets twice daily.

Administration

Vildagliptin and Metformin should be taken orally with a meal, twice a day. It should not be taken with alcohol or certain other medications. It should not be crushed, chewed, or dissolved in water.

Side Effect

Common side effects of Vildagliptin and Metformin include headache, nausea, vomiting, abdominal pain, diarrhea, dizziness and weakness. Severe side effects may include kidney failure, pancreatitis, and lactic acidosis.

Toxicity

Vildagliptin and Metformin may cause severe toxicity when taken in large doses or combined with other medications. In rare cases, lactic acidosis may occur, which is a potentially fatal condition. Signs and symptoms of lactic acidosis include difficulty breathing, nausea, abdominal pain, and fatigue.

Precaution

Before taking Vildagliptin and Metformin, tell your doctor if you have liver or kidney disease, or if you are pregnant or breastfeeding. Tell your doctor about all medications and supplements that you are taking.

Interaction

Vildagliptin and Metformin may interact with other medications. It should not be taken with alcohol or certain medications such as birth control pills and certain antibiotics. Be sure to tell your doctor about all medications or supplements that you are taking before starting treatment with Vildagliptin and Metformin.

Disease Interaction

Vildagliptin and Metformin can increase the risk of hypoglycemia (low blood sugar) in patients with certain diseases, such as diabetes, thyroid disease, and liver or kidney disease.

Drug Interaction

Vildagliptin and Metformin may interact with certain drugs. Tell your doctor about any medications or supplements that you are taking before starting Vildagliptin and Metformin.

Food Interactions

Vildagliptin and Metformin may interact with certain foods. For best results, take the medication as directed with meals.

Pregnancy Use

It is not recommended for use during pregnancy as there are not enough studies to determine the safety and efficacy of Vildagliptin and Metformin in pregnancy. Tell your doctor immediately if you become pregnant while on this medication.

Lactation Use

It is not recommended for use while breastfeeding as there are not enough studies to determine the safety and efficacy of Vildagliptin and Metformin while breastfeeding. Tell your doctor if you are breastfeeding before starting Vildagliptin and Metformin.

Acute Overdose

An acute overdose of Vildagliptin and Metformin can cause low blood sugar, nausea, vomiting, abdominal pain, and fatigue. Seek medical attention if an overdose is suspected.

Contraindication

Vildagliptin and Metformin is contraindicated in patients with hypersensitivity to metformin or vildagliptin, liver or kidney disease, and diabetic ketoacidosis.

Use Direction

Take Vildagliptin and Metformin exactly as your doctor prescribed it for you. Take the medication with meals and swallow it whole. Do not crush, chew, or dissolve it in water.

Storage Condition

Store Vildagliptin and Metformin at room temperature. Keep away from light, moisture, and heat. Do not store in the bathroom.

Volume of Distribution

Vildagliptin is well-distributed in the body, with a volume of distribution of approximately 0.7 L/kg. Metformin has a volume of distribution of 0.6-1.0 L/kg.

Half-life

The half-life of Vildagliptin is 12-18 hours and the half-life of Metformin is approximately 5-7 hours.

Clearance

Vildagliptin has a clearance of approximately 33 L/h and Metformin has a clearance of 5.3 L/h.

Here you find in details version of Viglimet

Some Frequently Asked Questions About Viglimet

please provide 1 to 3 lines only

What is Viglimet?

Viglimet is a combination medication. The medication combines two drugs that help lower blood sugar levels by different mechanisms. Vildagliptin helps to increase the amount of insulin secreted and Metformin helps reduce the production and absorption of glucose in the body.

What is Viglimet used for?

Viglimet is used to treat type 2 diabetes. It is used when other medications have not been successful in controlling blood sugar levels.

Who should not take Viglimet?

Patients who are allergic to vildagliptin or metformin, or any of the other ingredients in the medication should not take Viglimet. Patients who have kidney problems and who are taking insulin should also avoid taking this medication.

How should Viglimet be taken?

Viglimet should be taken once daily with food, as directed by a health care provider.

How long does it take for Viglimet to start working?

It may take up to 3 weeks for Viglimet to begin working. Blood sugar levels should be monitored regularly by a health care professional to determine if the medication needs to be adjusted.

What are the side effects of Viglimet?

The most common side effect of Viglimet is gastrointestinal upset, such as nausea, vomiting, and abdominal pain. Other potential side effects are low blood sugar, headache, and skin rash. Some serious side effects may also occur, such as low electrolytes or lactic acidosis.

Can Viglimet be taken with other medications?

Viglimet may interact with certain other medications or supplements, such as insulin or vitamins. Talk to a health care provider before taking other medications while taking Viglimet.

What should I do if I miss a dose of Viglimet?

If a dose of Viglimet is missed, it should be taken as soon as possible. If it has been more than 12 hours since the missed dose, then the missed dose should be skipped and the next regularly scheduled dose should be taken.

What should I do if I overdose on Viglimet?

If an overdose of Viglimet is suspected, seek medical attention immediately. Symptoms of an overdose may include difficulty breathing, confusion, or seizures.

Is Viglimet safe in pregnancy?

Viglimet is classified as a pregnancy category C drug, which means it may be unsafe to use during pregnancy. Talk to a doctor before taking Viglimet if you are pregnant or planning to become pregnant.

Can Viglimet be used to treat type 1 diabetes?

No, Viglimet is not recommended for use in patients with type 1 diabetes. This medication is only recommended for use in patients with type 2 diabetes.

What is the most common reason why Viglimet is prescribed?

The most common reason why Viglimet is prescribed is to help lower blood sugar levels in those with type 2 diabetes whose blood sugar is not controlled with other medications.

What should I do if I experience an allergic reaction to Viglimet?

If an allergic reaction occurs, stop taking Viglimet and seek medical attention immediately. Symptoms may include hives, difficulty breathing, or swelling of the face, lips, tongue, or throat.

Can Viglimet cause weight gain?

Weight gain is not a common side effect of Viglimet. However, if excessive weight gain occurs, talk to a doctor.

Does Viglimet cause low blood sugar?

Low blood sugar is a potential side effect of Viglimet. Hypoglycemia may occur, which can cause fatigue, sweating, blurred vision, confusion, or seizures. If these symptoms occur, talk to a doctor immediately.

Can I drink alcohol while taking Viglimet?

It is not recommended to drink alcohol while taking Viglimet. Alcohol can increase the risk of low blood sugar, which can be dangerous with this medication.

What is the recommended dosage of Viglimet?

The recommended dosage of Viglimet varies depending on the condition being treated and other factors. Talk to a doctor for specific dosage recommendations.

What should I do if I experience any side effects while taking Viglimet?

If any side effects occur while taking Viglimet, report them to a doctor or pharmacist as soon as possible. Some side effects may require medical attention.

Can I take Viglimet while breastfeeding?

Viglimet should not be taken while breastfeeding. If this medication is needed while breastfeeding, alternative treatments should be considered.

Why is it important to monitor my blood sugar while taking Viglimet?

It is important to monitor blood sugar levels because this medication may not fully control blood sugar levels. Adjustments may need to be made in medication dosage or additions made to the patient's treatment plan based on blood sugar readings.

Can Viglimet be taken with insulin?

Yes, Viglimet can be taken with insulin. However, it should only be done under the supervision of a health care provider.

Is Viglimet available in generic form?

Yes, Viglimet is available in generic form.

Does Viglimet lower my risk of heart attack or stroke?

Viglimet may not lower the risk of heart attack or stroke, but it may help reduce other risk factors associated with cardiovascular disease. Talk to a doctor about the risks and benefits of taking this medication.

What should I tell my doctor before taking Viglimet?

It is important to tell your doctor about any medical conditions, allergies, and medications that you are taking before taking Viglimet. This will help your doctor determine if this medication is safe and effective for you.

What should I do if I experience shortness of breath while taking Viglimet?

If shortness of breath occurs while taking Viglimet, contact a doctor immediately. This may be a sign of a serious complication.

Can Viglimet be used in children?

Viglimet is not approved for use in children. There may be alternative medications available that may be suitable for children, but only a doctor can determine the best course of treatment.

Can I drive while taking Viglimet?

It is generally safe to drive while taking Viglimet. However, low blood sugar or dizziness could affect your ability to operate a vehicle. If these side effects occur, it is best to avoid driving until the symptoms resolve.

Does Viglimet have any interactions with food?

Viglimet should be taken with food, but it is not known to interact with certain foods. If any side effects occur with this medication, contact a doctor.

Can Viglimet cause kidney problems?

Viglimet may cause kidney problems in some individuals, particularly those with pre-existing kidney conditions. It is important to follow the guidance of a health care provider when taking this medication.

Can I take Viglimet if I am pregnant?

Viglimet is classified as a pregnancy category C drug, which means it may be unsafe to use during pregnancy. Talk to a doctor before taking Viglimet if you are pregnant or planning to become pregnant.

Does Viglimet work for pre-diabetes?

Yes, Viglimet is sometimes prescribed for people with pre-diabetes who are at a high risk of developing type 2 diabetes. Talk to a doctor for specific recommendations.

What is the difference between Viglimet and other diabetes medications?

Viglimet is a combination medication that contains two drugs that help lower blood sugar levels in different ways. Other diabetes medications, such as insulin, work in different ways to manage blood sugar.

Can Viglimet be used by patients with liver disease?

Viglimet may not be suitable for some patients with liver disease. Talk to a doctor or pharmacist for more information.

Can I take other medications at the same time as Viglimet?

Viglimet may interact with other medications. Talk to a doctor or pharmacist before taking any other medications while taking this medication.

Does Viglimet cause hypoglycemia?

Yes, hypoglycemia is a potential side effect of Viglimet. Symptoms of hypoglycemia may include fatigue, sweating, blurred vision, confusion, or seizures. If any of these symptoms occur, contact a doctor.

Does Viglimet cause fatigue?

Fatigue is a potential side effect of Viglimet. Other potential side effects include gastrointestinal upset, low blood sugar, headache, and skin rash. Contact a doctor if any side effects occur.

How often should I monitor my blood sugar while taking Viglimet?

It is important to monitor blood sugar levels regularly while taking Viglimet. Talk to a doctor for specific recommendations about how often to monitor blood sugar.

What are the most important things to remember while taking Viglimet?

It is important to take Viglimet as directed by a doctor. Regularly monitor blood sugar levels with a health care professional and talk to a doctor if any side effects occur.

Do I need to take Viglimet with food?

Yes, Viglimet should be taken with food. If this medication is taken without food, it may not be as effective or it may cause serious side effects.

Can I take a multivitamin while taking Viglimet?

Talk to a doctor before taking a multivitamin or any other supplements while taking Viglimet. Some medications or supplements may interact with this medication.

Can I take