Vaxem Hib

Vaxem Hib Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Vaxem Hib is a brand name. Its generic name is Haemophilus Influenzae Type B Vaccine (Conjugated).

Introduction

Haemophilus influenzae type B (Hib) vaccine is a conjugated vaccine which is used for the prevention of infection against Haemophilus influenzae type B. This disease affects the respiratory system and can also result in meningitis, pneumonia, and other infections.

Uses For

The primary use for the Haemophilus influenzae type B conjugated vaccine is to prevent diseases such as meningitis, pneumonia, and other Haemophilus influenzae type B related infections. This vaccine can also be used as a booster for the protection against the disease.

Mechanism of Action

The Haemophilus influenzae type B conjugated vaccine works by triggering the body to produce antibodies. Antibodies are proteins formed by the body to destroy a foreign substance that cannot be eliminated or destroyed by other means. The antibodies attach to toxic, disease causing bacteria and prevents them from spreading.

How Long Does It Take to Work?

The vaccine usually takes approximately two weeks to take full effect and provide maximum protection against the disease.

Absorption

The vaccine is absorbed by the body rapidly, within 30 minutes of the injection.

Route of Elimination

The Haemophilus influenzae type B vaccine is primarily eliminated through urine.

Dosage

The recommended dosage of the Haemophilus influenzae type B (Hib) conjugated vaccine is as follows: Children ages 2 months to 5 years: 0.5ml intramuscularly (IM). Children age 6 years to 11 years: 0.5ml intramuscularly (IM) or 0.2ml subcutaneously (SC). Adults aged 12 years old and over: 0.5ml intramuscularly (IM) or 0.2ml subcutaneously (SC).

Administration

The vaccine is administered intramuscularly (IM) or subcutaneously (SC). In some cases, the intramuscular route may be preferred over the subcutaneous route, particularly for children 6 years and over. Intramuscular injection is usually given in the deltoid muscle, while the subcutaneous route is administered in the shoulder region or upper arm.

Side Effects

Common side effects associated with Haemophilus influenzae type B conjugated vaccine include:
  • Fever
  • Pain, swelling and redness at the injection site
  • Muscle soreness and fatigue
  • Headache
  • Nausea

Toxicity

The Haemophilus influenzae type B (Hib) conjugated vaccine has not been reported to cause serious adverse effects. However, mild or moderate adverse effects may still occur, such as those mentioned above.

Precautions

It is important to follow the appropriate instructions when administering the Haemophilus influenzae type B vaccine. It should only be used if the patient is not allergic to any of the components of the vaccine and the patient should not have had any adverse reactions to a prior dose of the vaccine. It is also important to store and handle the vaccine carefully according to the manufacturer’s instructions.

Interactions

The Haemophilus influenzae type B (Hib) conjugated vaccine may interact with other medications, vaccines, or herbal supplements. It is important to discuss all medications (prescription and non-prescription), vaccines, and supplements a patient is taking with their healthcare provider before receiving the Haemophilus influenzae type B vaccine.

Disease Interactions

This vaccine should not be administered to people with a weak immune system, due to the potential risk of further complications or a severe reaction to the vaccine. It is also not recommended for people with a history of anaphylaxis or any other severe allergic reactions.

Drug Interactions

The Haemophilus influenzae type B vaccine can interact with certain medications, such as antibiotics, and these interactions should be discussed with a healthcare provider before receiving the vaccine.

Food Interactions

No special dietary restrictions should be followed prior to receiving the Haemophilus influenzae type B (Hib) conjugated vaccine.

Pregnancy Use

The Haemophilus influenzae type B vaccine is not recommended for pregnant women due to the potential risk of harm to the fetus.

Lactation Use

It is not recommended to receive the Haemophilus influenzae type B (Hib) conjugated vaccine during lactation.

Acute Overdose

A single injection of the Haemophilus influenzae type B conjugated vaccine is unlikely to cause an overdose. However, if an overdose is suspected, immediate medical attention should be sought.

Contraindication

The Hib conjugated vaccine should not be administered to people with:
  • A weak immune system
  • History of anaphylaxis or other severe, allergic reactions.

Use Direction

The Haemophilus influenzae type B (Hib) conjugated vaccine should be administered either intramuscularly (IM) or subcutaneously (SC), depending on the patient's age and healthcare provider's recommendation.

Storage Condition

The Haemophilus influenzae type B (Hib) conjugated vaccine should be refrigerated between 2-8 degrees Celsius and not exposed to freezing temperatures.

Volume of Distribution

The volume of distribution for the Haemophilus influenzae type B (Hib) conjugated vaccine is not known.

Half Life

The half-life of the Haemophilus influenzae type B (Hib) conjugated vaccine is not known.

Clearance

The clearance of the Haemophilus influenzae type B (Hib) conjugated vaccine is not known.

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