Valdipin
Valdipin Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Valdipin is a brand name. Its generic name is Amlodipine + Valsartan.
Introduction
Valdipin is an antihypertensive medication that is used to treat hypertension. It is a combination of the calcium channel blocker Amlodipine and the angiotensin II receptor blocker Valsartan.Uses for
Valdipin is used to treat mild or moderate hypertension by lowering blood pressure and preventing associated complications such as stroke and cardiovascular disease.Mechanism Of Action
Valdipin works by blocking calcium channels in the blood vessels, causing them to relax and decrease blood pressure. Valsartan blocks the action of Angiotensin II, which normally causes the narrowing of certain blood vessels, and decreases blood pressure. Valsartan also increases the amount of circulating blood volume.How Long Does It Take To Work
The effects of Valdipin can be seen within two weeks of taking the medication, and it will normally reach its full effect within four to eight weeks.Absorption
Amlodipine is readily absorbed from the gastrointestinal tract and reaches maximal levels within 2 to 4 hours. Valsartan is also absorbed rapidly and peak effects occur 1-2 hours after administration.Route Of Elimination
Valdipin is eliminated partly by the kidneys and partly by the intestines.Dosage
The recommended adult starting dose of Valdipin is amlodipine 5mg/valsartan 160 mg once a day with or without food. Dosage may be increased as necessary. Maximum recommended dose is amlodipine 10mg/valsartan 320mg once a day.Administration
Valdipin should be taken orally with or without food once daily. Swallow the tablet whole and do not chew or break it.Side Effects
Side effects of Valdipin may include headache, dizziness, fatigue, nausea, abdominal pain, diarrhea.Toxicity
Valdipin is not considered toxic. However, the maximum daily recommended dose should not be exceeded and it should not be taken with grapefruit or grapefruit juice.Precautions
Patients using Valdipin should be monitored for any signs or symptoms of fluid accumulation, such as swelling of the ankles or feet, or shortness of breath. Patient should also inform their provider if they have a history of liver or kidney disease, heart disease, or if they have been prescribed diuretics.Interactions
Valdipin can interact with other medications, such as diuretics, angiotensin-converting enzyme inhibitors, potassium-sparing diuretics, potassium supplements, and birth control pills.Disease Interactions
Valdipin should not be used in patients with anuria, aortic stenosis, or severe hepatic impairment.Drug Interactions
Valdipin can interact with other drugs, such as diuretics, angiotensin-converting enzyme inhibitors, potassium-sparing diuretics, potassium supplements, and birth control pills.Food Interactions
Valdipin should not be taken with grapefruit or grapefruit juice, as grapefruit may interfere with the absorption of the medication.Pregnancy Use
Valdipin should not be used during pregnancy unless the benefit outweighs the risk.Lactation Use
Valdipin is not recommended for use in nursing mothers.Acute Overdoses
Patients who have taken an overdose of Valdipin should seek medical help as soon as possible. Symptoms of overdose may include hypotension, dizziness, and confusion.Contraindication
Valdipin is contraindicated in patients with anuria, aortic stenosis, or severe hepatic impairment.Use Direction
Valdipin should be taken once daily as prescribed by your doctor. Take the medication with or without food. Swallow the medicine whole, do not chew or break it.Storage Condition
Valdipin should be stored at room temperature and in a tight, light-resistant container.Volume Of Distribution
Amlodipine+Valsartan has a volume of distribution of 118L.Half Life
Amlodipine has a half-life of approximately 75 hours and Valsartan has a half-life of approximately 6 hours.Clearance
Amlodipine+Valsartan is eliminated mainly by cytochrome P450 enzyme system in the liver, with a smaller portion excreted unchanged in the urine.Here you find in details version of Valdipin
Some Frequently Asked Questions About Valdipin
What is Valdipin?
Valdipin is a combination medicine used to treat high blood pressure (hypertension). It contains two different medicines which help lower blood pressure: amlodipine and valsartan. Amlodipine is a calcium channel blocker that works by relaxing the muscles in your blood vessels to help lower your blood pressure. Valsartan is an angiotensin II receptor blocker that works by blocking the action of certain chemicals in your body that tighten your blood vessels, causing your blood pressure to go up.
How do I take Valdipin?
Valdipin should be taken as prescribed by your doctor. The usual starting dose for adults is 5 mg/160 mg, taken once daily. Your doctor may increase your dose if needed.
What are the possible side effects of Valdipin?
Common side effects include dizziness, headache, low blood pressure, fatigue, nausea, diarrhea, muscle cramps, and decreased heart rate. Less common side effects can include skin rash, joint pain, increased urination, decreased kidney function, chest pain, and heart failure. Talk to your doctor if you experience any of these side effects while taking Valdipin.
What should I do if I forget to take Valdipin?
If you miss a dose, take it as soon as you remember. If it is close to the time of the next dose, skip the missed dose and take your next dose at the regular time. Do not take a double dose of Valdipin.
Can I take Valdipin while pregnant?
It is not recommended that you take Valdipin while pregnant. Talk to your doctor if you are pregnant or planning to become pregnant while taking Valdipin.
Can I take Valdipin with other medications?
It is important to tell your doctor about all the medications you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Some medications can interact with Valdipin and affect how it works, so let your doctor know about all the medications you take.
What should I know before taking Valdipin?
Before taking Valdipin, tell your doctor about all your medical conditions, including if you have a history of heart problems, kidney disease, liver disease, are pregnant or planning to become pregnant, or if you are breastfeeding. Also tell your doctor about all the medications you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
Should I avoid taking other medications with Valdipin?
No, however it is important to tell your doctor about all the medications you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Some medications can interact with Valdipin and affect how it works, so your doctor needs to know about all the medications you take.
Does Valdipin cause weight gain?
Weight gain has been reported in people taking Valdipin. Tell your doctor if you are experiencing any changes in your weight while taking Valdipin.
Is Valdipin safe to take for a long time?
Valdipin is generally safe to take for a long time, however, it is important to talk to your doctor about any risks or concerns you may have. Your doctor will be able to discuss the benefits and risks for you.
Should I take Valdipin in the morning or at night?
Valdipin can be taken either in the morning or at night. It is best to take the medication at the same time each day to keep a consistent level in your blood. Talk to your doctor about the best time for you to take Valdipin.
What are the common side effects of Valdipin?
Common side effects include dizziness, headache, low blood pressure, fatigue, nausea, diarrhea, muscle cramps, and decreased heart rate. Less common side effects can include skin rash, joint pain, increased urination, decreased kidney function, chest pain, and heart failure. Talk to your doctor if you experience any of these side effects while taking Valdipin.
What should I do if I experience side effects from Valdipin?
If you experience any side effects from Valdipin, talk to your doctor or pharmacist. They may be able to adjust your dose or suggest alternatives. It is also important to tell your doctor about any other medications you are taking, as they can also cause side effects.
Can I drink alcohol while taking Valdipin?
Alcohol can increase the side effects of Valdipin. It is best to talk to your doctor about drinking alcohol while taking this medicine. If you decide to drink, do so in moderation.
Can I take a diuretic with Valdipin?
A diuretic may be taken with Valdipin if needed. Your doctor will be able to determine if a diuretic is necessary for your condition.
Are there any other medications I should avoid while taking Valdipin?
There are certain medications that should be avoided while taking Valdipin, including other angiotension-converting enzyme (ACE) inhibitors, angiotension-II receptor blockers (ARBs), calcium channel blockers (CCBs), potassium-sparing diuretics, trimethoprim-sulfamethoxazole, and non-steroidal anti-inflammatory drugs (NSAIDs). Check with your doctor or pharmacist to make sure your medications are safe to take with Valdipin.
What should I do if I experience an allergic reaction to Valdipin?
If you experience any signs of an allergic reaction, including hives, itching, skin rash, difficulty breathing, or swelling of your face, lips, tongue, or throat, seek medical attention immediately. Stop taking Valdipin and tell your doctor right away.
What happens if I overdose on Valdipin?
If you think you or someone else has overdosed on Valdipin, call 911 or your local poison control center right away. Symptoms of an overdose may include severe dizziness, slow heartbeat, confusion, difficulty breathing, and fainting.
Are there any foods or drinks I should avoid while taking Valdipin?
Alcohol and caffeine can increase the side effects of Valdipin. Avoid drinking large amounts of caffeine-containing beverages (e.g., coffee, tea, cola) or alcohol while you are taking this medication. Talk to your doctor about your diet and medications, as certain foods may interact with them.
Can Valdipin be used to treat other conditions?
Valdipin is mostly used to treat high blood pressure (hypertension). It may be used off-label to treat other conditions, however, only your doctor can determine if this is appropriate for your condition. Speak with your doctor about any other conditions you may have and if Valdipin is an appropriate treatment.
Will Valdipin help lower my blood pressure?
Valdipin is used to treat high blood pressure (hypertension). This medication can help lower your blood pressure over time. Follow your doctor's instructions and report any changes in your blood pressure to your doctor.
How quickly will I notice a difference after taking Valdipin?
The effects of Valdipin may take several weeks to become evident. You may begin to notice a lower blood pressure within a few weeks. Your doctor can monitor your blood pressure during treatment and adjust your dose if necessary.
Can I take Valdipin if I have a history of heart problems?
Valdipin can be used for people with a history of heart problems, however, your doctor may adjust your dose or use other medications to help control your symptoms. Your doctor will be able to determine the best treatment plan for you.
Will I need to have regular blood tests while taking Valdipin?
You may need to have regular blood tests while taking Valdipin. Your doctor will be able to determine if regular blood tests are necessary. Tell your doctor if you experience any changes in your blood pressure while taking Valdipin.
Can I take other medications with Valdipin?
It is important to tell your doctor about all the medications you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Some medications can interact with Valdipin and affect how it works, so let your doctor know about all the medications you take.
What should I do if I experience dizziness while taking Valdipin?
Dizziness is a common side effect of Valdipin. If you experience dizziness while taking this medication, contact your doctor. Avoid driving, operating machinery, or performing other hazardous activities until the dizziness passes.
Should I take Valdipin with food?
Valdipin can be taken with or without food. It is best to take the medication at the same time each day to keep a consistent level in your blood. Talk to your doctor about the best time for you to take Valdipin.
Can Valdipin be used to treat heart failure?
Valdipin may be used off-label to treat certain conditions, such as heart failure. Your doctor will be able to determine if this is an appropriate treatment for your condition.
Can Valdipin be used in children?
Valdipin is not indicated for use in children. Consult your doctor if you are considering treating a child with this medication.
Does Valdipin lower cholesterol?
Valdipin does not directly lower cholesterol. However, lower blood pressure can help improve cholesterol levels. If you are looking to lower your cholesterol, it is important to talk to your doctor about lifestyle changes, medications, and other treatments.
Does Valdipin cause hair loss?
Hair loss is not a common side effect of Valdipin. However, it has been reported in some people taking this medication. Talk to your doctor if you experience any changes in your hair while taking this medication.