Traneta
Traneta Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Traneta is a brand name. Its generic name is Linagliptin.
Traneta Introduction
Traneta is an oral anti-diabetic drug for the treatment of type 2 diabetes that belongs to the dipeptidyl peptidase 4 (DPP-4) inhibitor class. It is used together with a proper diet and exercise program to control high blood sugar. It works by reducing the amount of sugar (glucose) produced by the liver. It also increases the body’s sensitivity to insulin, enabling it more effectively to lower blood sugar.
Uses
Traneta is used to control high blood sugar levels in adults and children with type 2 diabetes. It is generally used in combination with proper diet and exercise program.
Mechanism of Action
Traneta blocks the enzyme dipeptidyl peptidase 4 (DPP-4) from breaking down the incretin hormones, which normally regulate glucose. By blocking DPP-4, Traneta increases levels of active incretin hormones, which reduce blood glucose.
How Long Does it Take to Work?
It may take up to 2 weeks before you notice an improvement in your blood glucose levels. Consult your doctor to determine if a change in your dosage is required.
Absorption
Traneta is slowly and completely absorbed from the gastrointestinal (GI) tract with peak plasma concentration achieved 0.5 to 1.5 hours after oral administration.
Route of Elimination
Traneta is mainly eliminated through bile as unchanged drug.
Dosage
Traneta is available in tablets of 5 mg and 10 mg. The recommended adult dosage for initial therapy is 5mg orally once daily. The recommended maintenance dosage is 10mg orally once daily. The dosage may be adjusted based on the response.
Administration
Traneta should be taken with or without food. It should be taken at the same time, each day.
Side Effect
The most common side effects associated with linagliptin include: headache, nausea, upper respiratory infection, runny nose, sore throat, and abdominal pain. Other side effects include dizziness, muscle pain, and back pain.
Toxicity
Traneta is generally considered safe and well-tolerated. There have been no reported cases of significant or acute toxicity.
Precautions
Patients should inform their doctor of any medical conditions, allergies, pregnancy, and breast-feeding before taking linagliptin. Patients with kidney disease or liver problems should use this medication with caution.
Interaction
Traneta may interact with other medications, including oral antidiabetic drugs, stimulants, and other medications. Consult your doctor before taking linagliptin if you are taking any other medications.
Disease Interaction
Traneta has not been studied in patients with significant hepatic or renal impairment. Therefore, caution should be used in these patients.
Drug Interactions
Traneta may interact with other medications, including oral antidiabetic drugs, stimulants, and other medications.
Food Interactions
Traneta is not affected by food and may be taken with or without food.
Pregnancy Use
Traneta is a pregnancy category B drug and is suggested not to be used during pregnancy unless necessary and as determined by your doctor.
Lactation Use
Traneta is excreted in human milk in small amounts. The potential risk of the infant should be considered before utilizing this drug.
Acute Overdose
In clinical studies, an overdose of 400mg of Traneta resulted in no serious adverse reactions. Other smaller overdoses have resulted in similar results with no serious adverse reactions.
Contraindication
Traneta is contraindicated in patients with a known sensitivity to the active ingredient or any of the excipients.
Use Direction
Take Traneta exactly as prescribed by your doctor. Do not take more than the recommended dose and do not stop taking this medication abruptly unless your doctor advises you to do so.
Storage Condition
Traneta tablets should be stored at room temperature, away from direct light and dampness.
Volume of Distribution
The volume of distribution of linagliptin is approximately 60 L.
Half Life
The half life of linagliptin is 13-16 hours.
Clearance
The renal clearance of linagliptin is approximately 12 liters/h. The hepatic clearance is approximately 4 liters/h.
Here you find in details version of Traneta
Some Frequently Asked Questions About Traneta
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## What is Traneta?
Traneta is a type of medication that works by controlling the levels of glucose (sugar) in your blood. It belongs to a group of medications called dipeptidyl peptidase-4 (DPP-4) inhibitors. It is used together with diet and exercise to lower blood glucose levels in adults with type 2 diabetes.
## What is Traneta used for?
Traneta is used along with a healthy diet and exercise to improve glycaemic (blood sugar) control in adults with type 2 diabetes. It is used when diet, exercise, and weight reduction have not been able to control your blood sugar levels well enough on their own.
##How does Traneta work?
Traneta works by blocking the action of a substance called dipeptidyl peptidase-4 (DPP-4). DPP-4 is an enzyme that breaks down the hormone GLP-1 (Glucagon-like peptide-1), which helps to control blood glucose levels. By blocking the action of DPP-4, Traneta helps to keep GLP-1 levels high, and this helps to control blood sugar levels.
## How long does it take for Traneta to work?
Traneta generally starts working within 24 hours of taking it. It usually takes 2-4 weeks for your glycaemic control to improve, however this can vary from person to person.
## Who can take Traneta?
Traneta is only suitable for adults. Generally, it is unsuitable for children under the age of 18. Your doctor will have checked your suitability for this medication.
## How is Traneta taken?
Traneta comes in the form of tablets which are taken orally with water. It is recommended that it is taken with food. The recommended dose is usually 5 mg once daily, however your doctor may prescribe a lower or higher dose depending on your individual circumstances.
## What are the side effects of Traneta?
The most common side effects of Traneta include headache, upper respiratory infections, and stuffy/ runny nose. Less common side effects may include abdominal pain, diarrhoea, nausea, and influenza. If you experience any side effects, you should speak to your doctor for advice.
## What should I do if I forget to take my Traneta?
If you forget to take a dose of Traneta, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue as normal. Do not take a double dose to make up for a missed dose.
## What other medications can interact with Traneta?
Traneta can interact with some other medications, such as laxatives, insulin, and other antidiabetic medications. It can also interact with antibiotics, antifungal medications, and some heart medications. It is important to tell your doctor about all medications you are taking before starting Traneta.
## Is Traneta safe to use during pregnancy?
Traneta is not recommended for use during pregnancy. It is important to speak to your doctor about the risks and benefits of taking this medication before starting it.
## Is it safe to take Traneta while breastfeeding?
It is generally not recommended to take Traneta while breastfeeding. It is important to speak to your doctor about the risks and benefits of taking this medication before deciding to take it.
## How long should I take Traneta for?
Traneta should be taken for as long as prescribed by your doctor. It is important not to stop taking this medication without consulting your doctor first.
## How does Traneta compare to other diabetes medications?
Traneta is generally well tolerated and has been shown to be effective in controlling blood glucose levels. However, as with all medications, it is important to assess the risks and benefits of taking this medication versus other available diabetes medications.
## What should I do if I experience severe side effects from Traneta?
If you experience any severe side effects while taking Traneta, it is important to seek medical advice immediately. You should stop taking the medication and contact your doctor for further advice.
## Is Traneta available over the counter?
Traneta is a prescription-only medication and is not available over the counter. You will need to have a doctor’s prescription before you can obtain this medication.
## What is the difference between Traneta and Sitagliptin?
Traneta and Sitagliptin are both DPP-4 inhibitors used to treat type 2 diabetes. They work in similar ways but have slightly different chemical structures. Generally, they are used in the same way, however your doctor may decide that one is more suitable for you than the other.
## How long does Traneta stay in the body?
Traneta has a half-life of approximately 14 hours, which means that it takes approximately 14 hours for the concentration of the medication in the blood to be reduced by 50%.
## Does Traneta cause weight gain?
It is not known conclusively whether Traneta causes weight gain in all people. Some people taking this medication may experience weight gain, however this is not a known side effect and should be discussed with your doctor.
## What are the potential risks of taking Traneta?
The potential risks associated with taking Traneta include increased liver enzymes, pancreatitis, allergic reactions, and potentially dangerous drops in blood sugar levels. It is important to speak to your doctor about the risks and benefits of this medication before starting it.
## Does Traneta cause hypoglycaemia?
Traneta has been associated with potentially dangerous drops in blood sugar levels (hypoglycaemia) in some people. It is important to consult your doctor if you experience symptoms of hypoglycaemia (such as dizziness, sweating, or a rapid heartbeat).
## Is it safe to take Traneta with other diabetes medications?
Traneta can be used in combination with other diabetes medications, such as insulin and metformin. However, it is important to speak to your doctor before starting any new medications to ensure they are suitable and will not interact with your other medications.
## Is Traneta safe for long-term use?
Traneta is generally safe for long-term use if used correctly and monitored regularly by your healthcare professional. However, it is important to speak to your doctor about the risks and benefits of taking this medication before deciding whether to take it long-term.
## What happens if I overdose on Traneta?
If you take too much Traneta it can be dangerous and can lead to potentially dangerous side effects such as hypoglycaemia or liver damage. It is important to seek immediate medical attention if you think you have taken too much of this medication.
## Does Traneta affect driving?
Traneta does not usually affect your ability to drive or operate machinery. However, if you experience any side effects such as dizziness, drowsiness or blurred vision while taking this medication, it is important to avoid driving or operating machinery.
## How do I store Traneta?
Traneta should be stored at room temperature, away from direct heat and light. It is important to keep this medication out of reach of children.
## Is Traneta available in generic form?
Yes, Traneta is available in generic form. However, it is important to speak to your doctor or pharmacist to confirm that the generic version of Traneta is suitable for you.
## Does Traneta need to be taken with meals?
It is recommended that Traneta is taken with a meal to reduce the risk of side effects such as diarrhoea and abdominal discomfort. Your doctor or pharmacist can give you further advice on this.
## Can I take other medicines with Traneta?
It is important to tell your doctor about all the medicines you are taking before starting Traneta, as some medicines may interact and cause side effects. Your doctor or pharmacist can advise you on medications which may interact with Traneta.
## What alternatives are available to Traneta?
There are a number of alternative medications available for type 2 diabetes, including metformin, sulfonylureas, thiazolidinediones, and GLP-1 receptor agonists. Your doctor can advise you on the best treatment plan for your individual needs.
## Is Traneta similar to insulin?
No, Traneta and insulin are not similar. Traneta is a DPP-4 inhibitor, which works by blocking the enzyme that breaks down GLP-1 (Glucagon-like peptide-1) to control blood glucose levels. Insulin, on the other hand, is a hormone that helps to reduce the amount of glucose in the blood by allowing it to be absorbed into body cells and used as energy.
## What is the most common side effect of Traneta?
The most common side effect of Traneta is headache. Other common side effects include upper respiratory infections, stuffy or runny nose, abdominal pain, and diarrhoea. If you experience any side effects, you should speak to your doctor for further advice.
## Is it safe to take Traneta if I have kidney disease?
Traneta is generally not recommended for people with severe kidney disease. Your doctor may decide to prescribe this medication if other diabetes medications are not suitable.
## Can I split the tablet of Traneta?
No, tablets of Traneta should not be split or crushed. It is important to take it as a whole tablet with water. If you find it difficult to swallow, you can ask your doctor or pharmacist for advice.
## Are there any foods I should avoid while taking Traneta?
It is important to follow a healthy, balanced diet while taking Traneta. This is because some foods can affect your blood sugar levels. Speak to your doctor or qualified nutritionist for advice on what to eat while taking this medication.
## Is Traneta suitable for people with type 1 diabetes?
No, Traneta is only suitable for people with type 2 diabetes. People with type 1 diabetes may be prescribed insulin to control their blood sugar levels.
## How often should I have my blood sugar levels monitored while taking Traneta?
It is generally recommended that you have your blood sugar levels monitored regularly while taking Traneta. The frequency of these tests will depend on your individual circumstances. Discuss this with your doctor or healthcare team.