Tramimed

Tramimed Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Tramimed is a brand name. Its generic name is Tramadol.

Tramimed

Tramimed, (generic name: tramadol hydrochloride), is an opioid medication used to treat moderate to severe pain. It is an opioid agonist, meaning it stimulates opioid receptors in the brain, activating them and producing an analgesic effect. Tramimed also works on serotonin and norepinephrine receptors, further enhancing its pain-relieving effect. Tramimed is available in both immediate-release and extended-release forms.

Uses For Tramimed

Tramimed is prescribed to treat moderate to severe pain in both adults and children, as well as in adolescents between the ages of 12 and 18. It is also used off-label to treat pain associated with fibromyalgia, painful neuropathy, and headaches. Because of its opiate-like effects, Tramimed is sometimes prescribed for the treatment of opioid dependence.

Mechanism Of Action

Tramimed works by binding to opioid receptors in the brain and spinal cord, and increasing the activity of serotonin (which helps reduce the pain signals sent to the brain). Tramimed also binds to the norepinephrine receptor, which further enhances its pain-relieving effect. The combination of its opioid and monoamine agonism is responsible for its analgesic effects.

How Long Does It Take To Work?

Tramimed typically begins to work within 30 minutes to an hour of being taken. The duration of its effects usually last about 4-6 hours. With extended-release tablets, effects may last up to 12 hours.

Absorption

Tramimed is rapidly and completely absorbed from the gut into the blood stream, with peak blood levels occurring one to two hours after ingestion. It is highly soluble in water, and rapidly distributed throughout the body.

Route Of Elimination

Tramimed is broken down and eliminated by the liver and kidneys. About 90% of an administered dose is eliminated via the kidneys, and 10% via the bile. It typically takes 4-6 hours for tramadol to be eliminated from the body.

Dosage

Dosage of Tramimed depends on the task of its use. A starting dose of the medication is usually 25-50mg every four to six hours, for which the maximum dose should not exceed 400mg in a day. For treating breakthrough pain, the dose can be increased to 150-200mg per day. Extended release tablets should be taken once a day, with the maximum dose not exceeding 300mg in a day.

Administration

Tramimed can be taken orally or administered through an IV. Oral tablets and capsules should be taken with food to reduce the risk of gastrointestinal adverse effects. Oral liquid preparations should be administered with a specifically designed measuring device, and not with a regular teaspoon.

Side Effect

Common side effects of Tramimed include nausea, vomiting, drowsiness, dizziness, headache, constipation, and dry mouth. Other side effects may include difficulty urinating, loss of appetite, sweating, confusion, and itchy skin. In some cases, more serious side effects such as respiratory depression, hallucinations, and seizures can occur.

Toxicity

Tramimed is generally considered safe and well-tolerated when used as prescribed. But at higher doses, especially when taken with other medications that also act on the central nervous system, it can be toxic, and may lead to serious respiratory depression, comas, and even death.

Precautions

Tramimed should be taken with caution, especially in individuals with a history of alcohol abuse or addiction, mental illness, thyroid problems, kidney or liver disease, or a history of convulsions, seizures, or head injury. Tramimed should not be taken concomitantly with MAO inhibitors, muscle relaxants, sedatives or other narcotic medications.

Interaction

Tramimed may interact with certain medications such as anticoagulants, antidepressants, monoamine oxidase inhibitors, drugs for high blood pressure, drugs for mental illness, antihistamines, muscle relaxants, and opioids, increasing the risk of toxicity and other side effects.

Disease Interaction

Tramimed may interact with certain diseases such as seizure disorders, head injury, liver or kidney disease, and respiratory depression, increasing the risk of toxicity and other side effects. Patients with any of these diseases should talk to their doctor before starting tramadol therapy.

Drug Interaction

Tramimed can interact with several drugs, including alcohol, Monoamine Oxidase inhibitors (MAOIs), anticoagulants, sedatives, muscle relaxants, and opioids. These interactions can increase the risk of toxicity and other side effects. Patients should check with their doctor before starting or stopping any medication while taking tramadol.

Food Interactions

Tramimed should be taken with food to reduce the risk of gastrointestinal adverse effects. Grapefruit juice should be avoided when taking tramadol, as it can increase the absorption of the drug and potentially increase its toxicity. Certain foods such as aged cheese, red wine, and pickled or smoked meats can also interact with tramadol.

Pregnancy Use

Tramimed is not recommended for use in pregnant women. It is not known whether the drug is harmful to developing babies or if it passes into breast milk. Women who are pregnant or breastfeeding should talk to their doctor before taking tramadol.

Lactation Use

Tramimed should not be used during breastfeeding. It is not known whether the drug is harmful to developing babies or if it passes into breast milk. Women who are breastfeeding should talk to their doctor before taking tramadol.

Acute Overdose

Overdose of tramadol can lead to respiratory depression, comas, and even death. Symptoms of an overdose can include pinpoint pupils, confusion, slowed breathing, seizure, and loss of consciousness. Treatment for an overdose may include administration of naloxone, an opioid antagonist, or other supportive care measures.

Contraindication

Tramimed is contraindicated in patients who are hypersensitive to it or any of its components. It is also contraindicated in patients who are taking MAO inhibitors, strong CYP3A4 inhibitors, and certain opioid drugs such as meperidine. Additionally, tramadol should not be taken in combination with alcohol or other CNS depressants.

Use Direction

Tramimed should be taken as directed by a physician. It should be taken with food to reduce the risk of gastrointestinal adverse effects. The dosage of tramadol should be adjusted based on patient’s response and symptoms. It should not be taken concomitantly with MAO inhibitors, muscle relaxants, sedatives, or other narcotic medications.

Storage Condition

Tramimed should be stored at room temperature in a light-resistant, child-resistant container. It should be kept away from heat and moisture, and out of the reach of children and pets.

Volume Of Distribution

Tramimed has a volume of distribution of 0.4L/kg, meaning that 0.4L of the drug is distributed throughout the body for every kg of the patient’s weight.

Half Life

Tramimed has a half-life of 4-6 hours, meaning it takes 4-6 hours for half of the drug to be eliminated from the body.

Clearance

Tramimed has a clearance rate of 0.11L/kg/hour, meaning that 0.11L of the drug is eliminated from the body every hour for every kg of the patient’s weight.

Here you find in details version of Tramimed

Some Frequently Asked Questions About Tramimed

What is Tramimed?

Tramimed is an opioid-type pain reliever (analgesic) used to treat moderate to moderately severe pain. It is available in both immediate-release and extended-release formulations.

What is the generic name of Tramimed?

Tramimed's generic name is Ultram.

What is the mechanism of action of Tramimed?

Tramimed works by binding to and activating opioid receptors located in the brain, which helps reduce the perception of pain.

Is Tramimed a controlled substance?

Yes, Tramimed is classified as a Schedule IV controlled substance in the United States, suggesting that it has a low potential for abuse.

How fast does Tramimed work?

Tramimed works within 30 minutes of taking a dose and its effects can last up to 4-6 hours.

How should Tramimed be taken?

Tramimed should be taken exactly as prescribed by the doctor. It can be taken with or without food but should not be crushed, split, or chewed before taking.

What are the side effects of Tramimed?

The most common side effects of Tramimed include nausea, vomiting, constipation, headache, dizziness, drowsiness, and dry mouth.

Can I take acetaminophen and Tramimed together?

Yes, acetaminophen and Tramimed can be taken together as long as the total daily dose of acetaminophen does not exceed 4,000 milligrams.

What are the signs of an overdose of Tramimed?

Signs of an overdose of Tramimed include extreme drowsiness, confusion, shallow breathing, faster heart rate, nausea, vomiting, and fainting.

Can Tramimed be used for back pain?

Yes, Tramimed is often prescribed for the treatment of back pain.

Is Tramimed addictive?

Yes, Tramimed can be addictive when taken in large amounts or for long periods of time.

What should I do if I forget to take a dose of Tramimed?

If you forget to take a dose of Tramimed, take it as soon as you remember, but do not double your dose. Call your doctor if you have any questions or concerns.

Can Tramimed be taken with alcohol?

No, Tramimed should not be taken with alcohol as it can increase the risk of side effects such as extreme drowsiness and respiratory depression.

Should I avoid caffeine while taking Tramimed?

Yes, as caffeine can increase the risk of nervousness, difficulty sleeping, and fast or irregular heartbeat.

Is Tramimed safe for long-term use?

Tramimed is generally considered safe for short-term use, but its effects can diminish with long-term use, increasing the risk of addiction and overdose.

Can Tramimed be taken during pregnancy?

Tramimed should not be taken during pregnancy as it can cause harm to the fetus.

Can I take Tramimed if I have a history of drug abuse?

No, Tramimed should not be taken if you have a history of drug abuse as it can be addictive and could cause relapse.

Will Tramimed show up on a drug test?

Yes, Tramimed may show up on a drug test, though the results may vary depending on the type of test.

Can I take Tramimed if I have liver or kidney disease?

Tramimed should be used with caution in patients with a history of liver or kidney disease, as they may be more sensitive to its effects.

Can I take Tramimed with anti-anxiety medications?

No, Tramimed should not be taken with anti-anxiety medications, as it may increase the risk of adverse reactions.

What should I do if I experience any side effects from Tramimed?

If you experience any side effects from Tramimed, contact your doctor as soon as possible.

What other pain relievers can be taken with Tramimed?

Tramimed can be taken with other non-opioid pain relievers such as ibuprofen and acetaminophen.

What is the maximum daily dose of Tramimed?

The maximum daily dose of Tramimed is 400 milligrams per day for adults.

Does Tramimed cause constipation?

Yes, constipation is a common side effect of Tramimed.

Can I take Tramimed and Tramimed Plus together?

No, Tramimed and Tramimed Plus should not be taken together as it may increase the risk of adverse reactions.

Can Tramimed be taken for headaches?

Yes, Tramimed is often prescribed for the treatment of headaches.

Is Tramimed ever prescribed for arthritis?

Yes, Tramimed is sometimes prescribed for the treatment of arthritis.

Does Tramimed interact with other medications?

Yes, Tramimed may interact with other medications, so it is important to discuss any other medications you are taking with your doctor before taking Tramimed.

Can Tramimed be taken for menstrual cramps?

Yes, Tramimed can be prescribed for the treatment of menstrual cramps.

Can Tramimed be crushed for easier swallowing?

No, Tramimed should not be crushed before taking because the medication may be released too quickly, leading to increased risk of side effects.

What other conditions can Tramimed be used to treat?

Tramimed may be prescribed to treat chronic pain, fibromyalgia, and neuropathic pain, among other conditions.

Can I take Tramimed while breastfeeding?

No, Tramimed should not be taken while breastfeeding as it can be passed through breast milk and could cause harm to a nursing baby.

Can Tramimed be taken with anti-depressants?

Yes, Tramimed can be taken with certain types of anti-depressants, but should not be taken with monoamine oxidase inhibitors (MAOIs).

Can Tramimed be taken with vitamins or supplements?

Yes, Tramimed can be taken with certain vitamins and supplements, but it is important to discuss any medications you are taking with your doctor before taking Tramimed.

Can Tramimed be taken with antihistamines?

Yes, Tramimed can be taken with certain antihistamines, but it is important to check with your doctor before taking any medication.

Can I take Tramimed with other pain relievers?

No, Tramimed should not be taken with other opioid-type pain relievers as this increases the risk of adverse reactions and overdose.

Is Tramimed metabolized by the liver?

Yes, Tramimed is metabolized in the liver and it is important to discuss any history of liver or kidney disease with your doctor before taking Tramimed.

How long will Tramimed stay in my system?

Tramimed can stay in the system for up to 24 hours after the last dose.

What should I do if I miss a dose of Tramimed?

If you miss a dose of Tramimed, take it as soon as you remember, but do not double your dose. Call your doctor if you have any questions or concerns.

Can I take Tramimed while taking other medications?

Yes, Tramimed can be taken with certain medications, but it is important to discuss any medications you are taking with your doctor before taking Tramimed.

Does Tramimed affect blood pressure?

Yes, Tramimed may cause an increase in blood pressure, so it is important to talk to your doctor if you have any concerns.

What is Tramimed HCL?

Tramimed HCL (hydrochloride) is a prescription medication used to treat pain. It is available in both immediate-release and extended-release formulations.

What are the withdrawal symptoms of Tramimed?

The withdrawal symptoms of Tramimed may include insomnia, agitation, anxiety, nausea, vomiting, sweating, and runny nose.

Can Tramimed cause hallucinations?

Yes, Tramimed can cause hallucinations, especially at higher doses.

Is Tramimed the same as Vicodin?

No, Tramimed and Vicodin are different medications. Tramimed is an opioid-type pain reliever while Vicodin is a combination of an opioid and acetaminophen.

Can Tramimed be taken with other medications for pain?

Yes, Tramimed can be taken with other medications for pain, but it is important to discuss any medications you are taking with your doctor before taking Tramimed.