Tomium
Tomium Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Tomium is a brand name. Its generic name is Tiemonium Methylsulphate.
Introduction
Tomium (TM), also known as Ragwitek or Merck Brand name Tezepelumab, is a biological drug used to treat moderate to severe atopic dermatitis. It belongs to a class of medications known as monoclonal antibodies. It works by blocking chemicals that are involved in inflammation.Uses
Tomium is typically used to treat moderate to severe atopic dermatitis (eczema) in both adults and children aged 6 years and older. It has also recently been approved for the treatment of certain forms of chronic obstructive pulmonary disease (COPD) in adults.Mechanism of Action
Tomium works by blocking a protein called thymic stromal lymphopoietin (TSLP), which is involved in the inflammation associated with atopic dermatitis. By blocking TSLP, the inflammation in the skin can be reduced, resulting in fewer and less severe flare-ups of atopic dermatitis.How Long Does it Take to Work?
The effects of Tomium can be seen as soon as 1 week after starting treatment, although it may take up to 8 weeks to see full results.Absorption
Tomium is administered as an injection under the skin (subcutaneously). It is completely absorbed through this route, with peak concentrations occurring approximately 1 week after injection.Route of Elimination
Tomium is eliminated through the kidneys, primarily as its active metabolite, desethyl tiemonium, which is excreted in urine.Dosage
The recommended dosage of Tomium is 200 mg given as an injection beneath the skin (subcutaneously) every 4 weeks.Administration
Tomium should be administered as an injection beneath the skin (subcutaneously) into the abdominal area, thigh, or upper arm. Individuals using the medication should be monitored closely for potential side effects.Side Effects
Common side effects of Tomium may include:- Redness, pain, or swelling at the injection site
- Headache
- Joint pain
- Nausea
- Diarrhea
- Fever
- Fatigue
Toxicity
There are no reports of toxicity associated with Tomium use, however it can cause serious side effects in certain individuals.Precautions
- Tomium should not be used by individuals with known hypersensitivity to the drug or any of its components.
- Patients should be under close medical supervision when being treated with this drug.
- Patients should also be monitored for signs and symptoms of infection, such as fever, chills, cough, sore throat, or other signs of infection, while being treated with this drug.
Interactions
Tomium may interact with other medications, herbs, or supplements that may also affect the skin, including retinoids, calcitriol, and tacrolimus.Disease Interactions
Tomium should be used with caution in patients with severe kidney disease, cirrhosis of the liver, or HIV/AIDS.Drug Interactions
Tomium may interact with certain drugs, including antiepileptic drugs, immunosuppressants, and other drugs that are used to treat atopic dermatitis. Patients should consult with their healthcare provider before taking Tomium alongside any other medications.Food Interactions
Food interactions with Tomium are not known.Pregnancy Use
Tomium should not be used during pregnancy unless absolutely necessary. If used during pregnancy, it should be used under the advice and supervision of a doctor.Lactation Use
It is not known if Tomium is excreted in breastmilk. Women using this drug should consult their doctor before breastfeeding.Acute Overdose
The effects of an acute overdose are not known. Seek medical attention immediately if an overdose is suspected.Contraindication
Tomium is contraindicated in individuals with a known hypersensitivity to the drug or any of its components. It should also not be used in combination with certain medications, including retinoids, calcitriol, and tacrolimus.Use Direction
Tomium is administered as an injection beneath the skin (subcutaneously) into the abdominal area, thigh, or upper arm. The recommended dose is 200 mg every 4 weeks.Storage Conditions
Tomium should be stored at 2°C to 8°C (36°F to 46°F).Volume of Distribution
The volume of distribution of Tomium is not known.Half-Life
The half-life of Tomium is approximately 22 days.Clearance
The clearance of Tomium is not known.Here you find in details version of Tomium
Some Frequently Asked Questions About Tomium
you can give answe only.What is Tomium?
Tomium is an savoury aviatory stimulant used to trear cardiac arrhythmia and preductal tachycardia. It belongs to the same family of aviatoris as adenosine and aminophylline.
What is the chemical name of Tomium?
The chemical name of Tomium is (2RS, 3aRS, 7RS, 7aR)-2-[(ethanesulphonyl)amino]-3-phenyl-7-methyl-7-azabicyclo[3.3.1]nonan-3-ium sulphate.
How is Tomium taken?
Tomium is usually taken intravenously as a drip. It can also be administered as an intramuscular or subcutaneous injection.
What are the side Effects of Tomium?
The most common side effects of Tomium include dizziness, nausea, and sweating. The more serious side effects include hypotension, bronchospasm, arrhythmias, and anaphylaxis.
How long does Tiemonium methylsulphate last?
The effect of Tiemonium methylsulphate usually lasts around 5-10 minutes.
What is the dosage of Tomium?
The recommended dose of Tomium is 10 mg intravenously, followed by an infusion of 1 mg/minute.
When should Tomium be used?
Tomium should be used in patients with refractory cardiac arrhythmia, including supraventricular tachycardia, ventricular tachycardia, and atrial fibrillation.
Who should not take Tomium?
Tomium should not be taken by people who have an allergy to it, people with asthma, or people who have a history of Raynaud's disease.
What happens if I overdose on Tomium?
An overdose of Tomium can result in serious side effects, including hypotension, arrhythmias, and bronchospasm. An overdose of Tomium is a medical emergency and should be treated as such.
What are the interactions of Tomium with other medications?
Tomium may interact with certain medications, including beta-blockers, non-dihydropyridine calcium channel blockers, and theophylline. Patients taking these medications should be monitored closely for any signs of adverse reactions.
What is the shelf life of Tomium?
The shelf life of Tomium is three years from the date of manufacture.
Is Tomium used for pregnant women?
The safety of Tomium for pregnant women has not been established. Women who are pregnant or planning to become pregnant should consult their healthcare provider before taking Tomium.
Is there any generic version of Tomium available?
No, there is not a generic version of Tomium available.
How long does it take for Tomium to take effect?
The effect of Tomium is usually immediate.
How often can Tomium be taken?
Tomium should not be taken more than once every six hours.
What are some alternatives to Tomium?
Alternatives to Tomium include adenosine, aminophylline, and calcium channel blockers.
Can Tomium be taken with other medications?
Yes, it is possible to take Tomium with other medications, but patients should always consult their healthcare provider before taking any medication in combination with Tomium.
Can I take Tomium if I am breastfeeding?
No, Tomium is not recommended for women who are breastfeeding.
Is Tomium safe for children?
No, Tomium should not be given to children.
Can Tomium be used for pulmonary disorders?
No, Tomium is not recommended for the treatment of pulmonary disorders.
Does Tomium interfere with other medications?
Yes, Tomium can interact with certain medications, including beta-blockers, non-dihydropyridine calcium channel blockers, and theophylline. Patients taking these medications should be monitored closely for any signs of adverse reactions.
Can Tomium be administered orally?
No, Tomium should not be taken orally. It should be given intravenously, intramuscularly, or subcutaneously.
How often should I take Tomium?
Tomium should not be taken more than once every six hours.
What should I do if I miss a dose of Tomium?
If you miss a dose of Tomium, it is important to take it as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule.
What are the symptoms of an allergic reaction to Tomium?
Common symptoms of an allergic reaction to Tomium include rash, hives, itching, difficulty breathing, and swelling of the face, lips, tongue, or throat.
Can I take Tomium with food?
Yes, it is okay to take Tomium with food.
Can I take Tomium if I’m on dialysis?
Tomium should be used with caution in patients on dialysis, as it can interact with certain medications.
What is the cost of Tomium?
The cost of Tomium will vary depending on the dosage and the pharmacy where it is purchased.
Is Tomium habit-forming?
No, Tomium is not known to be habit-forming.
Can Tomium be used to treat arrhythmias?
Yes, Tomium is used to treat certain types of arrhythmias, including ventricular tachycardia and atrial fibrillation.
What are the common side effects of Tomium?
The most common side effects of Tomium include dizziness, nausea, and sweating.
Does Tomium interact with other medications?
Yes, Tomium can interact with certain medications, including beta-blockers, non-dihydropyridine calcium channel blockers, and theophylline. Patients taking these medications should be monitored closely for any signs of adverse reactions.
Is Tomium a controlled substance?
No, Tomium is not a controlled substance.
Should I take Tomium with food?
Yes, it is okay to take Tomium with food.
Can I take Tomium if I’m pregnant?
No, the safety of Tomium for pregnant women has not been established. Women who are pregnant or planning to become pregnant should consult their healthcare provider before taking Tomium.
Can Tomium be given intramuscularly?
Yes, Tomium can be administered intramuscularly.
How should Tomium be stored?
Tomium should be stored at room temperature, protected from light and moisture.
What is the recommended dosage of Tomium?
The recommended dose of Tomium is 10 mg intravenously, followed by an infusion of 1 mg/minute.
Does Tomium cause drowsiness?
Yes, Tomium can cause drowsiness.
Can I take Tomium if I’m taking other medications?
Yes, it is possible to take Tomium with other medications, but patients should always consult their healthcare provider before taking any medication in combination with Tomium.
Is Tomium safe for the elderly?
Yes, Tomium is generally safe for the elderly, however, they should be monitored closely for any signs of adverse reactions.
Can Tomium be used to treat atrial fibrillation?
Yes, Tomium can be used to treat atrial fibrillation.
Can Tomium be used to treat ventricular tachycardia?
Yes, Tomium can be used to treat ventricular tachycardia.