Tobrel Plus
Tobrel Plus Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Tobrel Plus is a brand name. Its generic name is Dexamethasone + Tobramycin.
etcIntroduction
Tobrel Plus is a combination prescription medication used as an anti-inflammatory, anti-allergy, and anti-infective medication. It is a combination of dexamethasone, a corticosteroid, and tobramycin, an antibiotic. Tobrel Plus is used to treat inflammatory and allergic conditions, infections of the eye, skin, and lungs, and certain types of cancer.Uses For
Tobrel Plus is used to treat a variety of chronic and acute conditions, such as:- Infection from bacteria
- Inflammatory conditions
- Allergic reactions
- Eye, skin, and lung infections
- Certain types of cancer
Mechanism of Action
Tobrel Plus works by providing a combination of anti-inflammatory, anti-allergy, anti-infective, and anti-cancer effects. The dexamethasone acts to reduce inflammation and swelling, while the tobramycin works to reduce the infection caused by bacteria. Both medications act together to help reduce the symptoms of infection and inflammation.How Long Does It Take to Work?
The effects of Tobrel Plus should begin to be felt soon after it is taken. Most noticeably, inflammation and swelling should be reduced within hours of taking the medication.Absorption
Tobrel Plus is absorbed into the body in the small intestine and liver. Once absorbed, the combined effect of the medications should be noticeable within hours.Route of Elimination
Tobrel Plus is eliminated from the body primarily through the kidneys in the form of urine.Dosage
Tobrel Plus is available in different dosage forms and concentrations, based on the medical condition being treated. The usual recommended dosage is 0.3 mg/ml Tobramycin and 0.1 mg/ml Dexamethasone for adults, taken twice daily. The dose may be adjusted depending on the severity of the condition and the patient’s individual response to the medication.Administration
Tobrel Plus can be taken with or without food. The medication should be administered as directed by the physician, usually twice daily in the form of eye drops. For optimal absorption and effectiveness, it is recommended that Tobrel Plus be taken at evenly spaced intervals, not exceeding 12 hours between doses.Side Effect
The most common side effects associated with Tobrel Plus include burning, stinging, itching, or redness at the site of application; dryness, eye irritation, redness, and blurred vision; and nausea, vomiting, headache, and dizziness. Rarely, serious side effects may occur, such as signs of an allergic reaction (hives, difficulty breathing, swelling).Toxicity
Tobrel Plus is generally well-tolerated when used as directed. Rarely, an overdose may occur, leading to symptoms of toxicity. Symptoms can include nausea, vomiting, dizziness, headache, blurred vision, and stomach pain. If an overdose is suspected, seek immediate medical attention.Precaution
Before taking Tobrel Plus, it is important to inform the physician of any allergies or medical conditions. Patients with a history of glaucoma, eye infections, cataracts, or liver or kidney disease should use the medication with caution. It is important to use the medication exactly as prescribed and to not take more than the recommended dose.Interaction
Tobrel Plus may interact with other medications. It is important to inform the physician of any other medications being taken, including vitamins, minerals, herbal products, and prescription drugs.Disease Interaction
Tobrel Plus may interact with certain diseases. It is important to inform the physician of any existing diseases, such as diabetes, glaucoma, cataracts, kidney or liver disease, or any other medical conditions.Drug Interaction
Tobrel Plus may interact with other medications. In particular, it may interact with anti-fungal medications, certain antibiotics, medications used to treat diabetes, inflammation, or other conditions, and certain heart medications.Food Interactions
Tobrel Plus is not known to interact with foods. It is important to follow the instructions provided by the physician or on the packaging of the medication.Pregnancy Use
Tobrel Plus is not recommended for use during pregnancy. It is important to inform the physician of any current or suspected pregnancy before taking the medication.Lactation Use
Tobrel Plus is not recommended for use during lactation. It is important to inform the physician of any current or suspected medical condition before taking the medication.Acute Overdose
An overdose of Tobrel Plus can be dangerous and should be treated as a medical emergency. Symptoms of overdose may include nausea, vomiting, dizziness, headache, blurred vision, and stomach pain. Seek immediate medical attention if an overdose is suspected.Contraindication
Tobrel Plus is contraindicated in individuals with known hypersensitivity to either component or to any other ingredients in the formulation. It is also contraindicated in individuals with active bleeding, active infections, and in those with certain eye diseases.Use Direction
Tobrel Plus should be used as directed by the physician or as instructed on the packaging of the medication. The usual dose is 0.3 mg/ml Tobramycin, and 0.1 mg/ml Dexamethasone, taken twice daily. The dose may need to be adjusted depending on the severity of the condition and the patient’s individual response to the medication.Storage Condition
Tobrel Plus should be stored at room temperature away from heat, light, and moisture. It is important to keep the medication in the original packaging.Volume of Distribution
Tobrel Plus is distributed throughout the body, with concentrations highest in the eyes, skin, and lungs.Half Life
The half-life of Tobrel Plus is approximately 8 hours.Clearance
The clearance rate of Tobrel Plus is approximately 94 ml/min.Here you find in details version of Tobrel Plus
Some Frequently Asked Questions About Tobrel Plus
What is Tobrel Plus?
Tobrel Plus is a suspension used to treat eye infections caused by bacteria. It is a combination of two medications - dexamethasone (a steroid) and tobramycin (an antibiotic).
What are the benefits of Tobrel Plus?
Tobrel Plus is used to treat bacterial eye infections. It helps reduce inflammation and swelling, as well as fighting the infection.
How should I use Tobrel Plus?
Tobrel Plus should be used as directed by your healthcare provider. It should be administered into the affected eye once or twice a day, or as directed by your healthcare provider.
What are the side effects of Tobrel Plus?
The most common side effect of Tobrel Plus is blurred vision. Other side effects may include redness, dryness, irritation, and itching.
Are there any precautions I should take when using Tobrel Plus?
Yes. Avoid contaminating the tip of the ointment container or the eye dropper by not allowing it to touch any surface. Also, If you accidentally get Tobrel Plus in your nose or mouth, rinse the area thoroughly with water.
What should I do if I miss a dose of Tobrel Plus?
If you miss a dose of Tobrel Plus, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for the missed dose.
Is Tobrel Plus safe for pregnant women?
Tobrel Plus is not recommended for use in pregnant women unless the potential benefits outweigh the risks. Seek medical advice from your healthcare provider before using this medication if you are pregnant.
Can Tobrel Plus be used in children?
Yes, Tobrel Plus can be used in children. However, the dose must be adjusted according to the age and weight of the child. Seek advice from your healthcare provider before using this medication in children.
Can I use contact lenses while using Tobrel Plus?
No, it is advisable to avoid wearing contact lenses while using Tobrel Plus. The preservatives in the eye drops may cause irritation or other eye problems.
Can I use other eye drops while using Tobrel Plus?
No, you should not use other eye drops while using Tobrel Plus. Do not use this medication along with any other eye drops, unless directed by your healthcare provider.
Should I stop using Tobrel Plus after the infection has cleared up?
No, you should continue to use Tobrel Plus even after the infection has cleared up. Follow the instructions of your healthcare provider in completing the course of treatment. Do not stop using the medication even if you see improvement in your condition.
How long should I use Tobrel Plus?
The duration of treatment with Tobrel Plus varies from person to person and depends on the severity of the infection. Follow the advice of your healthcare provider regarding how long the medication should be used for and do not stop using the medication before completing the course of treatment.
Will my vision be affected while using Tobrel Plus?
Yes, your vision may be affected while using Tobrel Plus. You may experience blurred vision, redness, dryness, irritation, or itching in your eyes. These symptoms should improve shortly after discontinuing use of this medication.
Can Tobrel Plus cause serious eye infections?
Yes, in rare cases Tobrel Plus may cause serious eye infections. Seek immediate medical attention if you experience increased redness or pain in your eye, or if you experience light sensitivity or discharge from your eyes.
What should I do if I experience an allergic reaction while using Tobrel Plus?
If you experience an allergic reaction while using Tobrel Plus, seek immediate medical attention. Symptoms of an allergic reaction may include hives, difficulty breathing, and swelling of the face, lips, tongue, or throat.
Is it safe to use Tobrel Plus while breastfeeding?
Tobrel Plus is not recommended for use in breastfeeding women. Consult your healthcare provider before taking this medication if you are breastfeeding.
Can I take other medicines while using Tobrel Plus?
Yes, you can take other medicines while using Tobrel Plus. However, be sure to tell your healthcare provider about all medications, vitamins, and supplements that you are taking.
Can I wear eye makeup while using Tobrel Plus?
No, it is not recommended to wear eye makeup while using Tobrel Plus. The preservatives in the eye drops may cause irritation or other eye problems.
What should I do if I get Tobrel Plus in my nose or mouth?
If you accidentally get Tobrel Plus in your nose or mouth, rinse the area thoroughly with water. Contact your healthcare provider if irritation persists.
Should I avoid exposure to sunlight while using Tobrel Plus?
Yes, you should avoid exposure to direct sunlight or bright lights while using Tobrel Plus. The medication may cause sensitivity to sunlight and bright lights. Wear protective clothing and use sunscreen when you go outside.
Should I avoid activities such as driving while using Tobrel Plus?
Yes, you should avoid activities such as driving or operating machinery while using Tobrel Plus. This medication can cause blurred vision and drowsiness; therefore, it is important to avoid driving or operating machinery while taking this medication.
Does Tobrel Plus have any drug interactions?
Yes, Tobrel Plus may interact with some medications. Tell your healthcare provider about all medications, vitamins, and supplements that you are taking before using this medication.
Can Tobrel Plus be used to treat bacterial conjunctivitis?
Yes, Tobrel Plus can be used to treat bacterial conjunctivitis. Seek advice from your healthcare provider for more information regarding the use of this medication for bacterial conjunctivitis.
Will I need to have regular eye exams while using Tobrel Plus?
Yes, you will need to have regular eye exams while using Tobrel Plus. Your healthcare provider will need to monitor your condition and check the progress of your treatment.
Can I use Tobrel Plus if I have glaucoma?
No, Tobrel Plus is not recommended for use in people with glaucoma. Seek medical advice from your healthcare provider before using this medication if you have glaucoma.
Can Tobrel Plus be used to treat dry eyes?
Yes, Tobrel Plus can be used to treat dry eyes. However, the dosage may need to be adjusted according to the severity of your condition. Seek advice from your healthcare provider before using this medication for dry eyes.
Will Tobrel Plus cause drowsiness?
Yes, Tobrel Plus may cause drowsiness. Do not drive or operate machinery until you know how this medication will affect you.
Will Tobrel Plus cause blurred vision?
Yes, Tobrel Plus may cause blurred vision. This is a common side effect of the medication and should improve shortly after discontinuing use of this medication.
Can Tobrel Plus be used to treat corneal abrasions?
Yes, Tobrel Plus can be used to treat corneal abrasions. Seek advice from your healthcare provider for more information regarding the use of this medication for corneal abrasions.
Can Tobrel Plus be used to treat blepharitis?
Yes, Tobrel Plus can be used to treat blepharitis. Seek advice from your healthcare provider for more information regarding the use of this medication for blepharitis.
Can Tobrel Plus cause an eye infection?
Yes, in rare cases Tobrel Plus may cause an eye infection. Seek immediate medical attention if you experience intense redness or pain in your eye, or any other symptoms suggestive of an infection.
Can I use Tobrel Plus if I have an ulcer in my eye?
No, Tobrel Plus is not recommended for use in people with an ulcer in the eye. Seek medical advice from your healthcare provider before using this medication if you have an ulcer in your eye.
Can Tobrel Plus be used to treat allergic conjunctivitis?
Yes, Tobrel Plus can be used to treat allergic conjunctivitis. Seek advice from your healthcare provider for more information regarding the use of this medication for allergic conjunctivitis.
Can I share my Tobrel Plus with another person?
No, you should not share your Tobrel Plus with another person. This medication may have been prescribed specifically for you and could be harmful to another person if used.
Can Tobrel Plus be used to treat recurrent corneal erosion?
Yes, Tobrel Plus can be used to treat recurrent corneal erosion. Seek advice from your healthcare provider for more information regarding the use of this medication for recurrent corneal erosion.
Will Tobrel Plus cause permanent damage to my eyes?
No, Tobrel Plus will not cause permanent damage to your eyes. However, you should seek medical attention immediately if you experience any signs or symptoms suggestive of eye damage while taking this medication.
Can I wear soft contact lenses while using Tobrel Plus?
No, it is not recommended to wear soft contact lenses while using Tobrel Plus. The preservatives in the eye drops may cause irritation or other eye problems.
Can Tobrel Plus be used to treat uveitis?
Yes, Tobrel Plus can be used to