Titos
Titos Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Titos is a brand name. Its generic name is Tiemonium Methylsulphate.
Introduction
Titos (TM), also known as Ragwitek or Merck Brand name Tezepelumab, is a biological drug used to treat moderate to severe atopic dermatitis. It belongs to a class of medications known as monoclonal antibodies. It works by blocking chemicals that are involved in inflammation.Uses
Titos is typically used to treat moderate to severe atopic dermatitis (eczema) in both adults and children aged 6 years and older. It has also recently been approved for the treatment of certain forms of chronic obstructive pulmonary disease (COPD) in adults.Mechanism of Action
Titos works by blocking a protein called thymic stromal lymphopoietin (TSLP), which is involved in the inflammation associated with atopic dermatitis. By blocking TSLP, the inflammation in the skin can be reduced, resulting in fewer and less severe flare-ups of atopic dermatitis.How Long Does it Take to Work?
The effects of Titos can be seen as soon as 1 week after starting treatment, although it may take up to 8 weeks to see full results.Absorption
Titos is administered as an injection under the skin (subcutaneously). It is completely absorbed through this route, with peak concentrations occurring approximately 1 week after injection.Route of Elimination
Titos is eliminated through the kidneys, primarily as its active metabolite, desethyl tiemonium, which is excreted in urine.Dosage
The recommended dosage of Titos is 200 mg given as an injection beneath the skin (subcutaneously) every 4 weeks.Administration
Titos should be administered as an injection beneath the skin (subcutaneously) into the abdominal area, thigh, or upper arm. Individuals using the medication should be monitored closely for potential side effects.Side Effects
Common side effects of Titos may include:- Redness, pain, or swelling at the injection site
- Headache
- Joint pain
- Nausea
- Diarrhea
- Fever
- Fatigue
Toxicity
There are no reports of toxicity associated with Titos use, however it can cause serious side effects in certain individuals.Precautions
- Titos should not be used by individuals with known hypersensitivity to the drug or any of its components.
- Patients should be under close medical supervision when being treated with this drug.
- Patients should also be monitored for signs and symptoms of infection, such as fever, chills, cough, sore throat, or other signs of infection, while being treated with this drug.
Interactions
Titos may interact with other medications, herbs, or supplements that may also affect the skin, including retinoids, calcitriol, and tacrolimus.Disease Interactions
Titos should be used with caution in patients with severe kidney disease, cirrhosis of the liver, or HIV/AIDS.Drug Interactions
Titos may interact with certain drugs, including antiepileptic drugs, immunosuppressants, and other drugs that are used to treat atopic dermatitis. Patients should consult with their healthcare provider before taking Titos alongside any other medications.Food Interactions
Food interactions with Titos are not known.Pregnancy Use
Titos should not be used during pregnancy unless absolutely necessary. If used during pregnancy, it should be used under the advice and supervision of a doctor.Lactation Use
It is not known if Titos is excreted in breastmilk. Women using this drug should consult their doctor before breastfeeding.Acute Overdose
The effects of an acute overdose are not known. Seek medical attention immediately if an overdose is suspected.Contraindication
Titos is contraindicated in individuals with a known hypersensitivity to the drug or any of its components. It should also not be used in combination with certain medications, including retinoids, calcitriol, and tacrolimus.Use Direction
Titos is administered as an injection beneath the skin (subcutaneously) into the abdominal area, thigh, or upper arm. The recommended dose is 200 mg every 4 weeks.Storage Conditions
Titos should be stored at 2°C to 8°C (36°F to 46°F).Volume of Distribution
The volume of distribution of Titos is not known.Half-Life
The half-life of Titos is approximately 22 days.Clearance
The clearance of Titos is not known.Here you find in details version of Titos
Some Frequently Asked Questions About Titos
you can give answe only.What is Titos?
Titos is an savoury aviatory stimulant used to trear cardiac arrhythmia and preductal tachycardia. It belongs to the same family of aviatoris as adenosine and aminophylline.
What is the chemical name of Titos?
The chemical name of Titos is (2RS, 3aRS, 7RS, 7aR)-2-[(ethanesulphonyl)amino]-3-phenyl-7-methyl-7-azabicyclo[3.3.1]nonan-3-ium sulphate.
How is Titos taken?
Titos is usually taken intravenously as a drip. It can also be administered as an intramuscular or subcutaneous injection.
What are the side Effects of Titos?
The most common side effects of Titos include dizziness, nausea, and sweating. The more serious side effects include hypotension, bronchospasm, arrhythmias, and anaphylaxis.
How long does Tiemonium methylsulphate last?
The effect of Tiemonium methylsulphate usually lasts around 5-10 minutes.
What is the dosage of Titos?
The recommended dose of Titos is 10 mg intravenously, followed by an infusion of 1 mg/minute.
When should Titos be used?
Titos should be used in patients with refractory cardiac arrhythmia, including supraventricular tachycardia, ventricular tachycardia, and atrial fibrillation.
Who should not take Titos?
Titos should not be taken by people who have an allergy to it, people with asthma, or people who have a history of Raynaud's disease.
What happens if I overdose on Titos?
An overdose of Titos can result in serious side effects, including hypotension, arrhythmias, and bronchospasm. An overdose of Titos is a medical emergency and should be treated as such.
What are the interactions of Titos with other medications?
Titos may interact with certain medications, including beta-blockers, non-dihydropyridine calcium channel blockers, and theophylline. Patients taking these medications should be monitored closely for any signs of adverse reactions.
What is the shelf life of Titos?
The shelf life of Titos is three years from the date of manufacture.
Is Titos used for pregnant women?
The safety of Titos for pregnant women has not been established. Women who are pregnant or planning to become pregnant should consult their healthcare provider before taking Titos.
Is there any generic version of Titos available?
No, there is not a generic version of Titos available.
How long does it take for Titos to take effect?
The effect of Titos is usually immediate.
How often can Titos be taken?
Titos should not be taken more than once every six hours.
What are some alternatives to Titos?
Alternatives to Titos include adenosine, aminophylline, and calcium channel blockers.
Can Titos be taken with other medications?
Yes, it is possible to take Titos with other medications, but patients should always consult their healthcare provider before taking any medication in combination with Titos.
Can I take Titos if I am breastfeeding?
No, Titos is not recommended for women who are breastfeeding.
Is Titos safe for children?
No, Titos should not be given to children.
Can Titos be used for pulmonary disorders?
No, Titos is not recommended for the treatment of pulmonary disorders.
Does Titos interfere with other medications?
Yes, Titos can interact with certain medications, including beta-blockers, non-dihydropyridine calcium channel blockers, and theophylline. Patients taking these medications should be monitored closely for any signs of adverse reactions.
Can Titos be administered orally?
No, Titos should not be taken orally. It should be given intravenously, intramuscularly, or subcutaneously.
How often should I take Titos?
Titos should not be taken more than once every six hours.
What should I do if I miss a dose of Titos?
If you miss a dose of Titos, it is important to take it as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule.
What are the symptoms of an allergic reaction to Titos?
Common symptoms of an allergic reaction to Titos include rash, hives, itching, difficulty breathing, and swelling of the face, lips, tongue, or throat.
Can I take Titos with food?
Yes, it is okay to take Titos with food.
Can I take Titos if I’m on dialysis?
Titos should be used with caution in patients on dialysis, as it can interact with certain medications.
What is the cost of Titos?
The cost of Titos will vary depending on the dosage and the pharmacy where it is purchased.
Is Titos habit-forming?
No, Titos is not known to be habit-forming.
Can Titos be used to treat arrhythmias?
Yes, Titos is used to treat certain types of arrhythmias, including ventricular tachycardia and atrial fibrillation.
What are the common side effects of Titos?
The most common side effects of Titos include dizziness, nausea, and sweating.
Does Titos interact with other medications?
Yes, Titos can interact with certain medications, including beta-blockers, non-dihydropyridine calcium channel blockers, and theophylline. Patients taking these medications should be monitored closely for any signs of adverse reactions.
Is Titos a controlled substance?
No, Titos is not a controlled substance.
Should I take Titos with food?
Yes, it is okay to take Titos with food.
Can I take Titos if I’m pregnant?
No, the safety of Titos for pregnant women has not been established. Women who are pregnant or planning to become pregnant should consult their healthcare provider before taking Titos.
Can Titos be given intramuscularly?
Yes, Titos can be administered intramuscularly.
How should Titos be stored?
Titos should be stored at room temperature, protected from light and moisture.
What is the recommended dosage of Titos?
The recommended dose of Titos is 10 mg intravenously, followed by an infusion of 1 mg/minute.
Does Titos cause drowsiness?
Yes, Titos can cause drowsiness.
Can I take Titos if I’m taking other medications?
Yes, it is possible to take Titos with other medications, but patients should always consult their healthcare provider before taking any medication in combination with Titos.
Is Titos safe for the elderly?
Yes, Titos is generally safe for the elderly, however, they should be monitored closely for any signs of adverse reactions.
Can Titos be used to treat atrial fibrillation?
Yes, Titos can be used to treat atrial fibrillation.
Can Titos be used to treat ventricular tachycardia?
Yes, Titos can be used to treat ventricular tachycardia.