Tetabulin S/D
Tetabulin S/D Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Tetabulin S/D is a brand name. Its generic name is Human Tetanus Immunoglobulin.
Tetanus Immunoglobulin Introduction
Tetanus immunoglobulin (TIG) is a sterile solution of purified IgG antibody that is used to provide protection or treatment of tetanus. It is most frequently administered to patients suffering from a deep cut that has been exposed to a potentially tetanus-inducing bacteria such as Clostridium tetani. Tetanus immunoglobulin can also be administered either to provide a passive immunity or for post-exposure prophylaxis.Uses of Tetanus Immunoglobulin
Tetanus immunoglobulin (TIG) is mainly used for post-exposure prophylaxis against infection with tetanus bacteria. It is also used to provide passive immunity when the patient’s own antibody production is impaired, either due to a prior illness or condition, or when the patient has yet to develop an active immunity response.Mechanism of Action
Tetanus immunoglobulin acts by providing immediate, preformed tetanus antibodies to neutralize any active bacterial toxins that may be present. It also provides protection from the toxin produced by any newly colonizing tetanus bacteria. However, it does not provide any protection against further infection.How Long Does It Take to Work?
Tetanus immunoglobulin usually works within hours of administration. The preformed antibodies in the immunoglobulin provide immediate protection.Absorption
Tetanus immunoglobulin is not absorbed into the bloodstream, as it is a preparation of preformed antibodies.Route of Elimination
Tetanus immunoglobulin is mainly eliminated through the urine and feces.Dosage
The dosage of tetanus immunoglobulin varies depending on the age, weight, and size of the patient, as well as the severity of the infection. In adults, the standard dose is 250 to 500 IU, given as an intramuscular injection.Administration
Tetanus immunoglobulin should be administered intramuscularly (into a muscle), typically into the upper arm or buttock. It should not be administered intravenously (into a vein), as this can cause irritation and inflammation of the skin and tissues at the injection site.Side Effects
The most common side effects of tetanus immunoglobulin include soreness, redness, itching, or swelling at the injection site. Rare but serious side effects can include dizziness, difficulty breathing, chest pain, or an irregular heartbeat.Toxicity
Tetanus immunoglobulin is generally considered to be nontoxic when used as indicated.Precautions
Tetanus immunoglobulin should not be administered to patients who are hypersensitive to any components of the product. It should also not be given to patients who are pregnant, breastfeeding, or undergoing immunosuppressive therapy.Interactions
Tetanus immunoglobulin is known to interact with some medications such as phenytoin, tolbutamide, and warfarin. It may also interact with vaccines, such as the DTP and MMR vaccines.Disease Interactions
Tetanus immunoglobulin may interact with some diseases and conditions, including immunosuppression, HIV/AIDS, cancer, and organ transplantation.Drug Interactions
Tetanus immunoglobulin may interact with some drugs, including aspirin, ibuprofen, and certain antibiotics.Food Interactions
Tetanus immunoglobulin does not interact with food.Pregnancy Use
Tetanus immunoglobulin should not be used in pregnant women, as it may cross the placenta and cause harm to the fetus.Lactation Use
Tetanus immunoglobulin should not be used in breastfeeding women, as it may be excreted in breast milk and cause harm to the infant.Acute Overdose
An acute overdose of tetanus immunoglobulin is unlikely, as it is not absorbed into the bloodstream.Contraindication
Tetanus immunoglobulin is contraindicated in patients who are hypersensitive to any component of the product.Use Direction
Tetanus immunoglobulin should be administered intramuscularly. The dose may vary, based on the age, weight, and size of the patient, as well as the severity of the infection.Storage Condition
Tetanus immunoglobulin should be stored at temperatures between 2°C and 8°C.Volume of Distribution
Tetanus immunoglobulin is not absorbed into the bloodstream, and therefore does not have a volume of distribution.Half Life
The half-life of tetanus immunoglobulin is unknown, as it is not absorbed into the bloodstream.Clearance
Tetanus immunoglobulin is eliminated through the urine and feces, and has not been studied for clearance.Here you find in details version of Tetabulin S/D