Taflan

Taflan Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Taflan is a brand name. Its generic name is Tafluprost.

Taflan Introduction

Taflan is an ophthalmic solution used to reduce the intraocular pressure (IOP) in patients with glaucoma or ocular hypertension. It is the first prostaglandin analogue approved by the U.S. Food and Drug Administration (FDA). Taflan is a preservative-free, clear, colorless solution, which must be stored in the refrigerator.

Uses of Taflan

Taflan is beneficial in reducing the intraocular pressure in people who have been diagnosed with glaucoma or ocular hypertension. Its regular use can reduce the risk of vision loss due to these diseases.

Mechanism of Action

Taflan is a prostaglandin analogue, specifically a PGF2α analogue, which acts on the uveoscleral outflow pathway and facilitates the outflow of aqueous humor from the eye. This reduces the intraocular pressure. It also helps to reduce the elevated episcleral venous pressure, which is another contributing factor to elevated intraocular pressure.

How Long Does It Take to Work?

The results of Taflan treatment can be observed within 4 hours and reach its maximum efficacy at 12 hours.

Absorption

Taflan is rapidly absorbed after administration. It has been found to be up to 127 times more bioavailable than several other prostaglandin analogues.

Route of Elimination

Taflan is rapidly metabolized in the liver and is then eliminated through the kidneys.

Dosage

Taflan should be administered once a day in the evening. The recommended starting dose is one drop in the affected eye(s). It can be increased to two drops, if necessary. In cases where more than two drops are necessary, a second topical glaucoma therapy should be initiated.

Administration

Taflan should be administered into the conjunctival sac of the affected eye(s). It should not be instilled into the lower eyelid or in the eye itself. After using the eye drops, the person should not close their eyes for at least 60 seconds.

Side Effect

Common side effects of Taflan may include eye irritation, dry eyes, eye redness, watery eyes, increased pigmentation of eyelid magazines, increased pigmentation of the iris, itching, abnormal hair growth, and darkening of the affected eye(s).

Toxicity

No signs of toxicity have been observed following topical administration of tafluprost.

Precautions

Before using tafluprost, it is important to tell your doctor about any other medications or supplements you are taking. It is also important to inform your doctor if you have any allergies or if you have ever had any eye surgery.

Interactions

Taflan may interact with other drugs and supplements. It is important to tell your doctor about any of these interactions before you begin taking tafluprost.

Disease Interactions

Taflan should be used with caution in people with any active or chronic eye diseases. It should be used with extreme caution in people with corneal diseases, such as bullous keratopathy and herpetic keratitis.

Drug Interactions

Taflan may interact with certain drugs. Tell your doctor about any prescription, non-prescription, over-the-counter, and herbal medications you are taking or plan to take.

Food Interactions

Taflan should be used with food. Eating a meal may reduce the absorption and effectiveness of the medication.

Pregnancy Use

Taflan is generally not recommended for use in pregnant women.

Lactation Use

Taflan may pass into breast milk and should not be used by nursing mothers.

Acute Overdose

In case of an acute overdose, seek immediate medical attention. Symptoms of an acute overdose may include dizziness, headache, nausea, and visual disturbances.

Contraindication

Taflan is contraindicated in those with hypersensitivity to any of the ingredients in the product.

Use Direction

Taflan should be used exactly as prescribed by your doctor. The recommended dose is one drop in the affected eye(s) once daily in the evening. This can be increased to two drops if necessary. In cases where more than two drops are necessary, a second topical glaucoma therapy should be initiated.

Storage Condition

Taflan should be stored in the original closed package. It should then be kept in a refrigerator at a temperature between 2°C and 8°C.

Volume of Distribution

The volume of distribution of tafluprost has not been determined.

Half-Life

The elimination half-life of tafluprost has not been determined.

Clearance

The clearance of tafluprost has not been determined.

Here you find in details version of Taflan

Some Frequently Asked Questions About Taflan