Sviz Lfd

Sviz Lfd, a brand name for a formulation containing essential Artemether + Lumefantrine, is widely used for various health benefits. This guide provides comprehensive information on the uses, dosage, side effects, and mechanism of action of Sviz Lfd, as well as insights into how long it takes to work. Understanding these aspects can help you make informed decisions about its use and effectiveness.

What is Sviz Lfd?

Sviz Lfd (also known as Coartem or artemether + lumefantrine combination) is a combination medication used to treat malaria. It is a fixed-dose combination of two drugs, artemether (an antimalarial drug) and lumefantrine (a lipophilic allylamine).

Uses For Sviz Lfd

Sviz Lfd is used to help treat infected individuals with malaria and to reduce the spread of malaria in areas with a high infection rate. It may also be used to help treat recurrent acute attacks of malaria and lessen the severity of symptoms.

Mechanism of Action

Sviz Lfd works by interfering with the DNA of the Plasmodium parasite and blocking its growth. Artemether affects the building of the parasite's cell membrane and lumefantrine stops the spread of the parasites.

How Long Does it Take to Work?

Sviz Lfd starts to take effect within 2 days. However, it may take up to 2 weeks to clear the infection and up to 4 weeks for full recovery.

Absorption

Sviz Lfd is rapidly and almost completely absorbed from the gastrointestinal tract.

Route of Elimination

Sviz Lfd is primarily eliminated by the kidneys, although it may also be eliminated through bile or feces.

Dosage

The recommended dose for Sviz Lfd is 4 tablets twice daily, with food, for 3 days.

Administration

Sviz Lfd should be taken with food for maximum effectiveness.

Side Effects

The most common side effects of Sviz Lfd include nausea, abdominal pain, vomiting, and diarrhea. Other side effects may include anorexia, dizziness, headache, drowsiness, rash, pruritus, and insomnia.

Toxicity

The toxicity of Sviz Lfd is low. There have been reports of adverse events related to taking the combination medication, such as nausea, vomiting, and abdominal discomfort.

Precaution

Patients should inform their healthcare provider of any history of liver or kidney diseases, allergies, or other medical conditions before taking Sviz Lfd.

Interaction

Sviz Lfd may interact with other medications, including antacids, barbiturates, anticoagulants, penicillins, and phenytoin.

Disease Interaction

Sviz Lfd is not recommended for use in patients with severe renal impairment.

Drug Interaction

Sviz Lfd may interact with certain drugs, including cimetidine, ranitidine, phenobarbital, and rifabutin.

Food Interactions

Food may decrease the absorption of Sviz Lfd. It is best taken with food.

Pregnancy Use

Sviz Lfd may be used during pregnancy.

Lactation Use

Sviz Lfd is not recommended for use in breastfeeding women.

Acute Overdose

If an overdose occurs, it is important to seek medical attention immediately. Symptoms of an acute overdose may include nausea, vomiting, and abdominal pain.

Contraindication

Sviz Lfd is contraindicated in patients with a known hypersensitivity to any components of the medication.

Use Direction

Sviz Lfd should be taken as prescribed by a healthcare provider.

Storage Conditions

Sviz Lfd should be stored at room temperature in a cool, dry place.

Volume of Distribution

The volume of distribution of Sviz Lfd is estimated to be 0.91 L.

Half-Life

The estimated half-life of Sviz Lfd is 11 - 14 hours.

Clearance

The estimated clearance of Sviz Lfd is 0.28 L/hr.

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