Spason
Spason Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Spason is a brand name. Its generic name is Tiemonium Methylsulphate.
Introduction
Spason (TM), also known as Ragwitek or Merck Brand name Tezepelumab, is a biological drug used to treat moderate to severe atopic dermatitis. It belongs to a class of medications known as monoclonal antibodies. It works by blocking chemicals that are involved in inflammation.Uses
Spason is typically used to treat moderate to severe atopic dermatitis (eczema) in both adults and children aged 6 years and older. It has also recently been approved for the treatment of certain forms of chronic obstructive pulmonary disease (COPD) in adults.Mechanism of Action
Spason works by blocking a protein called thymic stromal lymphopoietin (TSLP), which is involved in the inflammation associated with atopic dermatitis. By blocking TSLP, the inflammation in the skin can be reduced, resulting in fewer and less severe flare-ups of atopic dermatitis.How Long Does it Take to Work?
The effects of Spason can be seen as soon as 1 week after starting treatment, although it may take up to 8 weeks to see full results.Absorption
Spason is administered as an injection under the skin (subcutaneously). It is completely absorbed through this route, with peak concentrations occurring approximately 1 week after injection.Route of Elimination
Spason is eliminated through the kidneys, primarily as its active metabolite, desethyl tiemonium, which is excreted in urine.Dosage
The recommended dosage of Spason is 200 mg given as an injection beneath the skin (subcutaneously) every 4 weeks.Administration
Spason should be administered as an injection beneath the skin (subcutaneously) into the abdominal area, thigh, or upper arm. Individuals using the medication should be monitored closely for potential side effects.Side Effects
Common side effects of Spason may include:- Redness, pain, or swelling at the injection site
- Headache
- Joint pain
- Nausea
- Diarrhea
- Fever
- Fatigue
Toxicity
There are no reports of toxicity associated with Spason use, however it can cause serious side effects in certain individuals.Precautions
- Spason should not be used by individuals with known hypersensitivity to the drug or any of its components.
- Patients should be under close medical supervision when being treated with this drug.
- Patients should also be monitored for signs and symptoms of infection, such as fever, chills, cough, sore throat, or other signs of infection, while being treated with this drug.
Interactions
Spason may interact with other medications, herbs, or supplements that may also affect the skin, including retinoids, calcitriol, and tacrolimus.Disease Interactions
Spason should be used with caution in patients with severe kidney disease, cirrhosis of the liver, or HIV/AIDS.Drug Interactions
Spason may interact with certain drugs, including antiepileptic drugs, immunosuppressants, and other drugs that are used to treat atopic dermatitis. Patients should consult with their healthcare provider before taking Spason alongside any other medications.Food Interactions
Food interactions with Spason are not known.Pregnancy Use
Spason should not be used during pregnancy unless absolutely necessary. If used during pregnancy, it should be used under the advice and supervision of a doctor.Lactation Use
It is not known if Spason is excreted in breastmilk. Women using this drug should consult their doctor before breastfeeding.Acute Overdose
The effects of an acute overdose are not known. Seek medical attention immediately if an overdose is suspected.Contraindication
Spason is contraindicated in individuals with a known hypersensitivity to the drug or any of its components. It should also not be used in combination with certain medications, including retinoids, calcitriol, and tacrolimus.Use Direction
Spason is administered as an injection beneath the skin (subcutaneously) into the abdominal area, thigh, or upper arm. The recommended dose is 200 mg every 4 weeks.Storage Conditions
Spason should be stored at 2°C to 8°C (36°F to 46°F).Volume of Distribution
The volume of distribution of Spason is not known.Half-Life
The half-life of Spason is approximately 22 days.Clearance
The clearance of Spason is not known.Here you find in details version of Spason
Some Frequently Asked Questions About Spason
you can give answe only.What is Spason?
Spason is an savoury aviatory stimulant used to trear cardiac arrhythmia and preductal tachycardia. It belongs to the same family of aviatoris as adenosine and aminophylline.
What is the chemical name of Spason?
The chemical name of Spason is (2RS, 3aRS, 7RS, 7aR)-2-[(ethanesulphonyl)amino]-3-phenyl-7-methyl-7-azabicyclo[3.3.1]nonan-3-ium sulphate.
How is Spason taken?
Spason is usually taken intravenously as a drip. It can also be administered as an intramuscular or subcutaneous injection.
What are the side Effects of Spason?
The most common side effects of Spason include dizziness, nausea, and sweating. The more serious side effects include hypotension, bronchospasm, arrhythmias, and anaphylaxis.
How long does Tiemonium methylsulphate last?
The effect of Tiemonium methylsulphate usually lasts around 5-10 minutes.
What is the dosage of Spason?
The recommended dose of Spason is 10 mg intravenously, followed by an infusion of 1 mg/minute.
When should Spason be used?
Spason should be used in patients with refractory cardiac arrhythmia, including supraventricular tachycardia, ventricular tachycardia, and atrial fibrillation.
Who should not take Spason?
Spason should not be taken by people who have an allergy to it, people with asthma, or people who have a history of Raynaud's disease.
What happens if I overdose on Spason?
An overdose of Spason can result in serious side effects, including hypotension, arrhythmias, and bronchospasm. An overdose of Spason is a medical emergency and should be treated as such.
What are the interactions of Spason with other medications?
Spason may interact with certain medications, including beta-blockers, non-dihydropyridine calcium channel blockers, and theophylline. Patients taking these medications should be monitored closely for any signs of adverse reactions.
What is the shelf life of Spason?
The shelf life of Spason is three years from the date of manufacture.
Is Spason used for pregnant women?
The safety of Spason for pregnant women has not been established. Women who are pregnant or planning to become pregnant should consult their healthcare provider before taking Spason.
Is there any generic version of Spason available?
No, there is not a generic version of Spason available.
How long does it take for Spason to take effect?
The effect of Spason is usually immediate.
How often can Spason be taken?
Spason should not be taken more than once every six hours.
What are some alternatives to Spason?
Alternatives to Spason include adenosine, aminophylline, and calcium channel blockers.
Can Spason be taken with other medications?
Yes, it is possible to take Spason with other medications, but patients should always consult their healthcare provider before taking any medication in combination with Spason.
Can I take Spason if I am breastfeeding?
No, Spason is not recommended for women who are breastfeeding.
Is Spason safe for children?
No, Spason should not be given to children.
Can Spason be used for pulmonary disorders?
No, Spason is not recommended for the treatment of pulmonary disorders.
Does Spason interfere with other medications?
Yes, Spason can interact with certain medications, including beta-blockers, non-dihydropyridine calcium channel blockers, and theophylline. Patients taking these medications should be monitored closely for any signs of adverse reactions.
Can Spason be administered orally?
No, Spason should not be taken orally. It should be given intravenously, intramuscularly, or subcutaneously.
How often should I take Spason?
Spason should not be taken more than once every six hours.
What should I do if I miss a dose of Spason?
If you miss a dose of Spason, it is important to take it as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule.
What are the symptoms of an allergic reaction to Spason?
Common symptoms of an allergic reaction to Spason include rash, hives, itching, difficulty breathing, and swelling of the face, lips, tongue, or throat.
Can I take Spason with food?
Yes, it is okay to take Spason with food.
Can I take Spason if I’m on dialysis?
Spason should be used with caution in patients on dialysis, as it can interact with certain medications.
What is the cost of Spason?
The cost of Spason will vary depending on the dosage and the pharmacy where it is purchased.
Is Spason habit-forming?
No, Spason is not known to be habit-forming.
Can Spason be used to treat arrhythmias?
Yes, Spason is used to treat certain types of arrhythmias, including ventricular tachycardia and atrial fibrillation.
What are the common side effects of Spason?
The most common side effects of Spason include dizziness, nausea, and sweating.
Does Spason interact with other medications?
Yes, Spason can interact with certain medications, including beta-blockers, non-dihydropyridine calcium channel blockers, and theophylline. Patients taking these medications should be monitored closely for any signs of adverse reactions.
Is Spason a controlled substance?
No, Spason is not a controlled substance.
Should I take Spason with food?
Yes, it is okay to take Spason with food.
Can I take Spason if I’m pregnant?
No, the safety of Spason for pregnant women has not been established. Women who are pregnant or planning to become pregnant should consult their healthcare provider before taking Spason.
Can Spason be given intramuscularly?
Yes, Spason can be administered intramuscularly.
How should Spason be stored?
Spason should be stored at room temperature, protected from light and moisture.
What is the recommended dosage of Spason?
The recommended dose of Spason is 10 mg intravenously, followed by an infusion of 1 mg/minute.
Does Spason cause drowsiness?
Yes, Spason can cause drowsiness.
Can I take Spason if I’m taking other medications?
Yes, it is possible to take Spason with other medications, but patients should always consult their healthcare provider before taking any medication in combination with Spason.
Is Spason safe for the elderly?
Yes, Spason is generally safe for the elderly, however, they should be monitored closely for any signs of adverse reactions.
Can Spason be used to treat atrial fibrillation?
Yes, Spason can be used to treat atrial fibrillation.
Can Spason be used to treat ventricular tachycardia?
Yes, Spason can be used to treat ventricular tachycardia.