Sitagil M
Sitagil M Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Sitagil M is a brand name. Its generic name is Sitagliptin + Metformin.
Introduction
Sitagil M is a combination of two oral medications - sitagliptin and metformin. Sitagliptin belongs to the class of medications called DPP-4 inhibitors and metformin belongs to the class of medications called biguanides. It is used together with diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.Uses
Sitagil M is used to lower blood sugar levels and improve glycemic control in people with type 2 diabetes mellitus (T2DM).Mechanism of Action
Sitagliptin works by inhibiting the enzyme responsible for the breakdown of incretin hormones, thereby increasing the amount of these hormones available to regulate blood sugar levels. It also increases insulin secretion. Metformin helps lower blood glucose levels by decreasing the amount of glucose absorbed from food in the intestine, increasing the body's sensitivity to insulin, and reducing the production of glucose by the liver.How Long Does It Take to Work
It typically takes several weeks to achieve an optimal response when using Sitagil M, and it is important to take the medication as directed.Absorption
Sitagliptin is rapidly absorbed in the gastrointestinal tract, and peak plasma concentrations are reached within 1 to 3 hours after oral administration. Metformin is absorbed more slowly, reaching peak concentrations 4 to 8 hours after oral adminstration.Route of Elimination
Sitagliptin is eliminated primarily through the urine. Metformin is partially eliminated through the feces but is primarily eliminated through the urine.Dosage
The dosage of Sitagil M will depend on several factors such as the patient's age, weight, kidney and liver function, and other medications. The usual starting dose is 100 mg sitagliptin and 1000 mg metformin, taken once daily in the morning with or without food. The maximum recommended daily dose is 100 mg sitagliptin and 2000 mg metformin.Administration
Sitagil M is administered orally, once each day, with or without food. It is important to take the medication as directed and not to skip doses.Side Effects
Common side effects of Sitagil M include headache, diarrhea, nausea, and vomiting. Rare side effects include severe allergic reactions, kidney damage, and pancreatitis.Toxicity
Overdoses of Sitagil M can lead to serious side effects including lactic acidosis, hypoglycemia, and increased risk of hypokalemia.Precautions
Patients should inform their healthcare provider about any other medications they are taking, any history of renal or liver impairment, and any allergic reactions to similar medications.Interaction
Sitagil M may interact with other medications, changing the effectiveness of either medication. It is important to inform the healthcare provider of all medications a patient is taking before beginning treatment with Sitagil M.Disease Interaction
Sitagil M may interact with certain pre-existing medical conditions, increasing the risk of side effects. Patients should inform the healthcare provider of any medical history before starting treatment with Sitagil M.Drug Interactions
Sitagil M may interact with certain medications, changing the effectiveness of either one. It is important to inform the healthcare provider of all medications a patient is taking before beginning treatment with Sitagil M.Food Interactions
Certain foods may interact with Sitagil M, changing the effectiveness of either one. Foods high in sugar can affect blood sugar levels and should be avoided. It is also important to limit alcohol intake while taking Sitagil M.Pregnancy Use
Sitagil M should be used with caution in pregnant women. Patients should inform the healthcare provider of any pregnancy before beginning treatment.Lactation Use
Sitagil M should not be used in breastfeeding women.Acute Overdose
Acute overdoses of Sitagil M can lead to hypoglycemia, lactic acidosis, and other serious side effects. Patients should seek emergency medical attention if an overdose is suspected.Contraindication
Sitagil M is contraindicated in patients with severe renal impairment and in patients with moderate to severe renal impairment. It is also contraindicated in patients with diabetic ketoacidosis.Use Direction
Patients should take Sitagil M as directed by the healthcare provider. It is typically taken once a day, with or without food.Storage Conditions
Sitagil M should be stored at room temperature, away from light and moisture.Volume of Distribution
The volume of distribution of Sitagil M ranges from 13 to 18 L/kg.Half-life
The plasma half-life of Sitagil M is approximately 6 to 8 hours.Clearance
The renal clearance of Sitagil M is approximately 124 mL/min.Here you find in details version of Sitagil M
Some Frequently Asked Questions About Sitagil M
What is Sitagil M?
Sitagil M is a combination medication used to control blood glucose levels in adults with Type 2 diabetes mellitus. It contains the active ingredients sitagliptin and metformin, which work together to lower blood sugar levels.
What are the side effects of Sitagil M?
The most common side effects of Sitagil M are diarrhea, nausea, headache, upper respiratory infection, sore throat, muscle pain, and rash. Other rarer side effects include low blood sugar, lactic acidosis, and liver problems.
How should I take Sitagil M?
Sitagil M should be taken exactly as prescribed, typically once or twice daily. It is important to take the medication with meals and follow the instructions of your doctor. It is also important to monitor your blood sugar levels regularly while taking this medication.
Is Sitagil M safe to use?
Yes, Sitagil M is generally safe if taken as prescribed and monitored regularly for blood glucose levels. However, it is important to talk to your doctor before starting this medication to understand any potential risks and benefits.
Can I drink alcohol while taking Sitagil M?
It is not advised to drink alcohol while taking Sitagil M, as the combination can increase your risk of experiencing hypoglycemia. It is best to talk to your doctor about potential risks associated with consuming alcohol while taking this medication.
Is Sitagil M expensive?
The cost of Sitagil M depends on where you purchase it. Many drugstores and online pharmacies have generic options available, which may be less expensive. Additionally, some insurance plans may cover part or all of the cost of this medication.
Can Sitagil M be used for other conditions?
No, Sitagil M should only be used to control blood sugar levels in adults with Type 2 diabetes mellitus. It is not intended for other health conditions or purposes.
What should I do if I miss a dose of Sitagil M?
If you miss a dose of Sitagil M, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue as normal with the regular dosing schedule. Do not take a double dose to make up for the missed one.
Are there any drug interactions with Sitagil M?
Yes, there are certain medications that may interact with Sitagil M. These include certain antibiotics, arthritis medications, seizure medications, and diuretics. It is important to tell your doctor about all the medications you are currently taking before startingthis medication, so they can assess for any potential interactions.
Can Sitagil M be taken with other diabetes medications?
Yes, Sitagil M can be taken with other diabetes medications. However, it is important to talk to your doctor before combining other diabetes medications with this one, as some medications may have an increased risk of side effects or drug interactions when taken together.
What if I experience severe side effects while taking Sitagil M?
If you experience severe side effects while taking Sitagil M, such as lactic acidosis, severe abdominal pain, or signs of an allergic reaction, it is important to seek medical attention as soon as possible.
Does Sitagil M have any long-term effects?
There are currently no known long-term effects associated with Sitagil M use. It is important to talk to your doctor about any potential risks and carefully monitor your blood glucose levels while taking this medication.
Can children take Sitagil M?
No, Sitagil M is not approved for use in children. It should only be taken by adults with Type 2 diabetes mellitus.
Can I take Sitagil M while pregnant?
No, Sitagil M is not approved for use in pregnant women. It is important to talk to your doctor about any potential risks associated with taking this medication while pregnant.
Can I take Sitagil M while breastfeeding?
No, Sitagil M is not approved for use in breastfeeding women. It is important to talk to your doctor about any potential risks associated with taking this medication while breastfeeding.
Can I drive after taking Sitagil M?
Yes, it is generally safe to drive after taking Sitagil M. However, it is important to monitor your blood sugar levels regularly while taking this medication, as low blood sugar levels can cause dizziness or drowsiness that could be hazardous when driving.
Can I get Sitagil M over-the-counter?
No, Sitagil M is not available over-the-counter, and a prescription is required to get it. It is important to talk to your doctor about other diabetes treatments available.
Can I take Sitagil M if I have liver problems?
No, Sitagil M should not be taken if you have liver problems. It is important to talk to your doctor about other diabetes treatments that would be safe for you to take.
What diet should I follow while taking Sitagil M?
It is important to follow a healthy diet while taking Sitagil M. This includes eating a variety of fruits and vegetables, whole grains, and lean proteins, and limiting your intake of sugar, saturated fats, and processed foods. Additionally, it is important to exercise regularly and talk to your doctor about other lifestyle modifications that may help manage your diabetes.
Does Sitagil M have any food interactions?
There are no known food interactions with Sitagil M. However, it is important to talk to your doctor about any potential risks associated with taking other medications with certain foods.
How quickly will I see the effects of Sitagil M?
The effects of Sitagil M can typically be seen within 4 weeks. However, it is important to monitor your blood sugar levels regularly and talk to your doctor about any changes in your blood sugar levels.
Can I stop taking Sitagil M on my own?
No, Sitagil M should only be stopped on the advice of a doctor. It is important to talk to your doctor about any potential risks associated with abruptly stopping this medication.
What happens if I overdose on Sitagil M?
If you suspect an overdose, call your local emergency services immediately. Overdoses of Sitagil M can cause severe side effects such as lactic acidosis, nausea, vomiting, and abdominal pain.
Can I take vitamins while taking Sitagil M?
Yes, it is generally safe to take vitamins while taking Sitagil M. However, it is important to talk to your doctor about any potential interactions between vitamins and this medication.
Is Sitagil M prescribed for Type 1 diabetes?
No, sitagliptin + Metformin is only prescribed for Type 2 diabetes. For Type 1 diabetes, other medications and lifestyle modifications may be recommended to control blood sugar levels.
Can Sitagil M cause weight gain?
No, Sitagil M is not known to cause weight gain. In fact, some patients may experience weight loss while taking this medication. It is important to talk to your doctor about any changes to your weight while taking this medication.
Should I take Sitagil M with food?
Yes, Sitagil M should be taken with food. Taking this medication with food helps to increase absorption and decreases the risk of gastrointestinal side effects.
Do I need to take Sitagil M every day?
Yes, Sitagil M should be taken every day, as prescribed by your doctor. It is important to take this medication as directed and monitor your blood sugar levels regularly.
How can I store Sitagil M?
Sitagil M should be stored at room temperature, away from direct light. It is important to keep all medications out of reach of children and pets.
What other treatments are available for Type 2 diabetes?
Other treatments for Type 2 diabetes may include lifestyle modifications such as diet and exercise, other oral medications, insulin injections, and other injectable medications. It is important to talk to your doctor about other treatments that may be suitable for you.
Does Sitagil M help with weight loss?
No, Sitagil M does not directly help with weight loss. However, some patients may experience weight loss while taking this medication. It is important to talk to your doctor about a healthy diet and exercise plan that may help with weight loss.
Does Sitagil M lower A1C levels?
Yes, Sitagil M can help lower A1C levels in people with Type 2 diabetes. It is important to monitor your A1C levels regularly while taking this medication and talk to your doctor about any changes.
Should I take Sitagil M in the morning or evening?
Sitagil M can be taken either morning or evening. However, it is important to take this medication at the same time each day, as prescribed by your doctor.
Are there any alternatives to Sitagil M for Type 2 diabetes?
Yes, there are other medications and lifestyle modifications available that may be suitable for people with Type 2 diabetes. It is important to talk to your doctor about other treatments that may be suitable for you.
Can I take other medications while taking Sitagil M?
Yes, you can take other medications while taking Sitagil M. However, it is important to tell your doctor about all the medications you are currently taking, as certain medications may have an increased risk of side effects or drug interactions when taken together.
Can Sitagil M be used to treat pre-diabetes?
No, Sitagil M is not intended to treat pre-diabetes. Lifestyle modifications can help manage pre-diabetes and delay or prevent the progression to Type 2 diabetes.
What should I do if I experience low blood sugar while taking Sitagil M?
If you experience low blood sugar (hypoglycemia) while taking Sitagil M, it is important to treat it right away. This may include eating or drinking a sugary snack or beverage, such as juice, glucose tablets, or a soft drink. It is important to talk to your doctor about treating hypoglycemia and other potential risks associated with this medication.
Can I take Sitagil M if I have kidney problems?
No, Sitagil M should not be taken if you have kidney problems. It is important to talk to your doctor about other diabetes treatments that would be safe for you to take.