Sintel
Sintel Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Sintel is a brand name. Its generic name is Telmisartan.
Introduction
Sintel is a medication that belongs to the angiotensin-II receptor blocker (ARB) class. It is used to treat high blood pressure (hypertension), heart failure, and other related disorders.Uses
Sintel is used to treat hypertension and heart failure. It is also indicated for the prevention of cardiovascular morbidity in high-risk patients, and for reducing the risk of stroke and other major cardiovascular events. It can also be used to prevent kidney damage in diabetic patients.Mechanism of Action
Sintel works by blocking the actions of angiotensin-II (a protein that causes blood vessels to constrict) and thereby widening the blood vessels so that the pressure of the blood is reduced.How Long Does it Take to Work?
Generally, the effects of telmisartan can be seen within 2 weeks of starting the medication. However, it may take up to 4 weeks of regular use for the effects of the medication to become fully evident.Absorption
Sintel is well absorbed from the gastrointestinal tract with peak plasma concentrations being achieved in 3-4 hours after an oral dose.Route of Elimination
The majority of the telmisartan is eliminated unchanged in the urine, via active tubular secretion.Dosage
The recommended dose of telmisartan is 20-80 mg orally once per day. The dose should be adjusted based on the patient's response and should not exceed 80 mg once daily.Administration
Sintel should be taken orally with food or a glass of water, once daily. It is not recommended to crush, chew or split the tablets.Side Effects
Common side effects of telmisartan include dizziness, headache, fatigue, diarrhea, stomach pain, and increased urination. Less common but serious side effects include liver damage, fainting, and elevated blood sugar levels.Toxicity
Sintel is relatively safe and well-tolerated. Overdose of telmisartan may cause hypotension (low blood pressure), hyperkalemia (high potassium levels in the blood), and bradycardia (slow heart rate).Precaution
Patients should inform their doctor about any medical history, the use of any other prescription or over-the-counter medications, as well as supplements and vitamins prior to taking telmisartan. Sintel should be used with caution in pregnant or breastfeeding women.Interaction
Sintel may interact with other medications such as potassium-sparing diuretics, potassium supplements, angiotensin-converting enzyme (ACE) inhibitors (such as lisinopril, enalapril), and nonsteroidal anti-inflammatory drugs (NSAIDs).Disease Interaction
Patients with diabetes, hypertension, congestive heart failure, liver disease, or kidney disease should use telmisartan with caution and be monitored more closely by a doctor.Drug Interaction
Use of telmisartan with certain drugs, including angiotensin-converting enzyme (ACE) inhibitors (such as lisinopril, enalapril), diuretics, nonsteroidal anti-inflammatory drugs (NSAIDs), and potassium-sparing agents may increase the risk of adverse effects.Food Interactions
Sintel should be taken with food for optimal absorption.Pregnancy Use
Sintel should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.Lactation Use
Sintel is not recommended for use in breastfeeding mothers as it is excreted in breast milk and may cause adverse reactions in the infant.Acute Overdose
If an overdose of telmisartan is suspected, the patient should be monitored for symptoms of hypotension and hypovolemia (low blood volume). Treatment of overdose involves supportive care, which may include intravenous fluids, sympatomimetic agents (such as epinephrine), and diuretics.Contraindication
Sintel is contraindicated in patients with hypersensitivity to any of the ingredients of the medication, severe hepatic impairment, and in patients with biliary cirrhosis.Use Direction
Sintel should be used as directed by the doctor. It is generally recommended to take the dose in the morning to avoid it interfering with sleep.Storage Condition
Sintel should be stored at room temperature, between 15°C and 30°C. Keep medication away from light, moisture, and heat. Store out of reach of children and pets.Volume of Distribution
Sintel has a volume of distribution of 11L/kg.Half Life
The elimination half-life of telmisartan is 24 hours.Clearance
The oral clearance of telmisartan is 1.3 L/hour/kg.Here you find in details version of Sintel
Some Frequently Asked Questions About Sintel
What is Sintel?
Sintel is a type of medication used to treat high blood pressure (hypertension) and heart failure. It is known as an angiotensin II receptor blocker, which works by blocking the hormone angiotensin so as to widen blood vessels, helping to reduce blood pressure and improve the flow of blood around the body.
What are the benefits of Sintel?
Sintel is used to treat high blood pressure (hypertension) and heart failure. It can also help reduce the risk of stroke, heart attack, and cardiac death in patients who have already had cardiovascular events. It is also used to decrease the risk of kidney failure due to diabetes, as well as to reduce stress and fatigue.
How does Sintel work?
Sintel works by blocking the action of the hormone angiotensin II, which is involved in narrowing of blood vessels. This helps to widen blood vessels, reducing blood pressure and improving the flow of blood around the body.
How long does it take for Sintel to work?
It usually takes 4-6 weeks for Sintel to start working. The full effect on blood pressure may not be seen for up to 8 weeks after starting treatment.
Is Sintel safe?
Sintel is generally well tolerated and considered safe for use by most patients, however it should not be taken if you are pregnant, have an allergy to angiotensin II receptor blockers, or have persistent liver problems. Always speak to your doctor before taking any medication.
Who should not take Sintel?
Sintel should not be taken by pregnant women, those with an allergy to angiotensin II receptor blockers, and those with persistent liver problems. It should also not be taken during breastfeeding.
What are the side effects of Sintel?
The most common side effects of Sintel are headache, dizziness, and fatigue. Other side effects include nausea, diarrhea, and rash. If any of these side effects become severe, contact your doctor.
What happens if I miss a dose of Sintel?
If you miss a dose of Sintel, take it as soon as you remember. However, if it is close to the time for your next dose, then skip it and take the next dose as normal. Do not take a double dose to make up for a missed one.
What should I avoid while taking Sintel?
Avoid drinking alcohol while taking Sintel, as it can increase the risk of side effects. Also, avoid taking other medications or supplements which might interact with Sintel. Ask your doctor for a list of medications or supplements to avoid, as some can increase the risk of side effects.
Can I drive or operate heavy machinery while taking Sintel?
It is generally safe to drive or operate heavy machinery while taking Sintel. However, always speak to your doctor if you experience any dizziness or fatigue while taking this medication, as it could affect your ability to concentrate or react quickly.
What happens if I overdose on Sintel?
If you overdose on Sintel, seek emergency medical attention. Overdose symptoms may include a rapid heartbeat, difficulty breathing, muscle weakness, light-headedness, and dizziness.
Does Sintel interact with any other medications?
Yes, Sintel may interact with other medications, including nonsteroidal anti-inflammatory drugs (NSAIDs), diuretics, and certain heart medications. Always tell your doctor about any medications you are taking before starting Sintel.
What should I tell my doctor before taking Sintel?
Before taking Sintel, you should tell your doctor about any existing medical conditions or allergies you have, as well as any medications you are currently taking. This will help to avoid any potential side effects or interactions.
Is there a generic version of Sintel available?
Yes, some generic versions of Sintel are available. Make sure to speak to your doctor or pharmacist to see if this would be a suitable option for you.
Is Sintel available over-the-counter?
No, Sintel is only available with a prescription. You will need to talk to your doctor about whether Sintel is the right choice for you.
How long do I need to take Sintel?
The duration of Sintel treatment will depend on why you are taking it, as well as your individual circumstances. Your doctor will be able to advise you on an appropriate course of treatment.
Is Sintel safe for long-term use?
Yes, Sintel is generally safe for long-term use, but always speak to your doctor about any potential risks. It is also important to be regularly monitored while taking this medication.
Can Sintel be taken with other medications?
Yes, Sintel can be taken with other medications. However, it is important to talk to your doctor before taking any additional medications, as some may interact with Sintel in a harmful way.
Is Sintel safe during pregnancy?
No, Sintel is not safe during pregnancy and should not be taken by pregnant women. Talk to your doctor about other treatments which may be suitable.
Can I take nonsteroidal anti-inflammatory drugs (NSAIDs) while taking Sintel?
No, NSAIDs should not be taken while taking Sintel, as they can interact in a harmful way and increase the risk of side effects. Talk to your doctor or pharmacist about other medications which may be suitable.
Can I take Sintel if I have kidney problems?
Yes, it is generally safe to take Sintel if you have kidney problems. However, always speak to your doctor about potential risks before taking this medication.
Can Sintel cause erectile dysfunction?
Sintel could potentially cause erectile dysfunction. Contact your doctor if you experience any issues related to your sexual health while taking this medication.
Can Sintel cause weight gain?
Sintel could potentially cause weight gain in some cases. Consult your doctor if you are concerned about weight gain while taking this medication.
Could Sintel cause hair loss?
It is unlikely that Sintel would cause hair loss. However, if you notice any changes in your hair while taking Sintel, consult your doctor.
Does Sintel affect potassium levels?
Sintel has been known to increase potassium levels in the blood. It is important to have regular blood tests to monitor your potassium levels while taking this medication.
Can Sintel make me sleepy?
Yes, Sintel can cause fatigue and dizziness. If this occurs, contact your doctor. Do not drive or operate heavy machinery if you experience this side effect.
Can I take ibuprofen while taking Sintel?
No, ibuprofen should not be taken while taking Sintel, as it can interact in a harmful way and increase your risk of side effects. Talk to your doctor about other pain relief options.
Is Sintel a diuretic?
No, Sintel is not a diuretic. It is an angiotensin II receptor blocker which works by blocking the hormone angiotensin II.
Does Sintel cause coughing?
Sintel could potentially cause coughing in some cases. If you experience coughing while taking this medication, contact your doctor.
Can Sintel cause dizziness?
Yes, Sintel can cause dizziness in some cases. If you experience dizziness, contact your doctor. Do not drive or operate heavy machinery if you experience this side effect.
Can Sintel cause muscle pain?
Yes, Sintel could potentially cause muscle pain in some cases. If you experience muscle pain or any other side effects while taking this medication, contact your doctor.
Is Sintel a Beta-blocker?
No, Sintel is not a Beta-blocker. It is an angiotensin II receptor blocker which works by blocking the hormone angiotensin II.
Can Sintel cause high potassium levels?
Yes, Sintel has been known to increase potassium levels in the blood. It is important to have regular blood tests to monitor your potassium levels while taking this medication.
Does Sintel need to be taken with food?
No, Sintel does not need to be taken with food. However, it is important to take it at the same time each day to maintain a consistent level in your bloodstream.
Can Sintel cause bloating?
Yes, Sintel could potentially cause bloating in some cases. If you experience bloating while taking this medication, contact your doctor.
Should I take Sintel if I have diabetes?
Yes, Sintel can be taken if you have diabetes. However, always speak to your doctor before taking any medications, as some may interact with one another in a harmful way.
Can I take Sintel if I have asthma?
Yes, Sintel can be taken if you have asthma. However, always speak to your doctor before taking any medications, as some may interact with one another in a harmful way.
Can Sintel cause a sore throat?
Sintel could potentially cause a sore throat in some cases. If you experience a sore throat while taking this medication, contact your doctor.
Can Sintel cause dehydration?
Yes, Sintel could potentially cause dehydration in some cases. If you experience any symptoms of dehydration while taking this medication, contact your doctor.
Is Sintel generic or brand name?
Sintel is the brand name for the medication. Some generic versions of Sintel are available, however always speak to your doctor or pharmacist before taking any generic medications.
Is Sintel water soluble?
Yes, Sintel is water soluble. This means that it can be absorbed into the bloodstream quickly.