Sinamin
Sinamin Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Sinamin is a brand name. Its generic name is Chlorpheniramine.
Sinamin Introduction
Sinamin is an antihistamine used to treat the symptoms of hay fever, allergies, the common cold, hives and other types of allergies. It works by blocking the action of histamine, a substance produced by the body when it becomes hypersensitive to an allergen. It helps to relieve sneezing, itching, stuffy nose, and watery eyes caused by these conditions.Sinamin Uses
Sinamin is used to treat a variety of allergic conditions, including hay fever, allergic rhinitis, hives, and contact dermatitis. It is also used to treat nausea and vomiting caused by certain drugs or conditions, such as chemotherapy or motion sickness.Sinamin Mechanism of Action
Sinamin blocks the effects of histamine, a chemical produced by the body during an allergic reaction. Histamine attaches to H1 receptors, which are found in the nose, skin, lungs, and gastrointestinal tract. When it attaches to these receptors, it causes sneezing, itching, watery eyes, and other symptoms of an allergic reaction. Sinamin blocks the action of histamine on H1 receptors, leading to relief of symptoms.How Long Does Sinamin Take to Work?
Sinamin typically takes 30 minutes to 1 hour to start working. However, in some cases it may take up to 4 hours to start working.Sinamin Absorption, Route of Elimination and Dosage
Sinamin is absorbed rapidly from the gastrointestinal tract. It is then quickly metabolized by the liver and eliminated from the body primarily through the kidneys. The recommended dose for chlorpheniramine is 4 mg to 8 mg in adults taken every 4-6 hours. For children, the dose depends on age and weight: 2-5 years: 2 mg; 6-11 years: 4mg; 12 years and older, the adult dose of 4-8mg.Sinamin Administration
Sinamin is available as a tablet and liquid suspension. It can be taken orally with or without food.Sinamin Side Effects
Common side effects of chlorpheniramine include drowsiness, dry mouth, stomach upset, dizziness, headache, and fatigue.Sinamin Toxicity
Sinamin is generally well tolerated but overdose of the medication may cause toxicity. Symptoms of overdose include confusion, convulsions, difficulty breathing, dry mouth, drowsiness, muscle twitching, nausea and vomiting, pale skin, rapid heart rate, and restlessness.Sinamin Precaution
Sinamin should be used with caution in patients with liver or kidney disease, glaucoma, narrow angle glaucoma, prostate hypertrophy, and urinary retention. It should also be used with caution in elderly patients, as they are more likely to be sensitive to the sedative effects of the drug.Sinamin Interaction, Disease Interaction, Drug Interaction, and Food Interactions
Sinamin can interact with medications used to treat anxiety, depression, forearm, high blood pressure, diabetes, epilepsy, and insomnia. It can also interact with alcohol, sedatives, muscle relaxants, and opioid pain medications. Sinamin can interact with certain diseases or medical conditions, such as asthma, heart disease, high blood pressure, kidney disease, liver disease, and urinary retention. Sinamin may interact with other medications or herbal supplements taken at the same time. It is important to tell your doctor about all the medications or supplements you are taking before using chlorpheniramine. Sinamin can interact with certain foods, such as high-fat foods, coffee, and grapefruit juice. It is important to tell your doctor about all the foods you eat before taking chlorpheniramine.Pregnancy and Lactation Use
Sinamin should be used with caution during pregnancy, as it may cause harm to the developing fetus. It is not recommended for use during lactation.Acute Overdose
Overdose of chlorpheniramine can cause severe side effects, including drowsiness, confusion, convulsions, difficulty breathing, dry mouth, flushing, muscle twitching, nausea, restlessness, shallow breathing, and slow/irregular heartbeat.Contraindication
Sinamin is contraindicated in patients with known hypersensitivity to the drug.Use Direction
Sinamin should be taken orally with or without food, as directed by your doctor. The dose for adults is 4 mg to 8 mg taken every 4-6 hours. The dose for children 2-5 years is 2 mg. The dose for children 6-11 years is 4mg. The dose for children 12-years and older is the same as for adults.Storage Condition
Sinamin tablets and liquid suspension should be stored at room temperature, away from moisture and heat. Keep out of reach of children.Volume of Distribution, Half Life, Clearance
Sinamin has a volume of distribution of 0.64 L/kg following intravenous administration. The elimination half-life of chlorpheniramine is 14 hours in adults and 30 hours in children. The clearance of chlorpheniramine is 2.5 L/hr/kg in adults and 6.3 L/hr/kg in children.Here you find in details version of Sinamin
Some Frequently Asked Questions About Sinamin
What is Sinamin?
Sinamin is an antihistamine that is used to treat a variety of allergic reactions including seasonal allergies, hay fever and other upper respiratory allergies. It works by blocking the effects of histamine, a substance in the body that causes allergy symptoms.
What are the side effects of Sinamin?
The most common side effects of this drug include dry mouth, drowsiness, nausea and dizziness. Other side effects may include headaches, constipation, blurred vision, confusion, irritability and decreased appetite.
What are the dosages for Sinamin?
The dosages may vary depending on the patient's age and weight. It is available in tablet, syrup and injection form. For adults, the usual dose is 4-8 milligrams taken orally every 4-6 hours, maximum of 24 milligrams in 1 day. For children, the usual dose is 0.4 milligrams per kilogram of body weight every 6-12 hours, maximum of 4 milligrams per kilogram in 1 day.
Can Sinamin be used for children?
Yes, it can be used for children over the age of 2. However, it is important to consult your pediatrician before giving it to a child.
Can I take Sinamin with other medications?
Yes, it can be taken with other medications, but it is important to consult your doctor before taking any other medication while taking Sinamin.
What are the interactions of Sinamin?
Sinamin may interact with other medications, such as monoamine oxidase inhibitors (MAOIs), sympathomimetics, narcotic analgesics, anticholinergics, bronchodilators, muscle relaxants, and other antihistamines. It is important to consult your doctor before taking any other medications while taking Sinamin.
Does Sinamin cause drowsiness?
Yes, Sinamin may cause drowsiness in some people. Therefore, it is important to use caution when driving, operating machinery, or performing any activity that requires alertness.
Is it ok to drink alcohol while taking Sinamin?
No, it is not recommended to drink alcohol while taking Sinamin as it can increase the risk of side effects.
Does Sinamin cause weight gain?
No, Sinamin does not cause weight gain. However, some people may experience increased appetite or cravings while taking this medication.
Can I take Sinamin while pregnant?
It is not recommended to take Sinamin while pregnant, as it may be harmful to the fetus. Consult your doctor before taking this medication if you are pregnant.
How long does Sinamin take to work?
It usually takes 30-60 minutes for Sinamin to begin working. However, the effects may vary depending on the severity of the allergic reaction.
How long does Sinamin stay in your system?
The half-life of Sinamin is 8-14 hours, which means that it takes about 8-14 hours for the body to eliminate half of the dose. It is usually eliminated from your system within 3 days of stopping the medication.
How should I store Sinamin?
Sinamin should be stored at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets.
Is Sinamin habit-forming?
No, Sinamin is not habit-forming, but it can cause mild dependence if it is taken regularly for an extended period of time. This means that it may be harder for the body to respond to it if it is abruptly stopped.
What is Sinamin used to treat?
Sinamin is used to treat a variety of allergic reactions including seasonal allergies, hay fever and other upper respiratory allergies.
Can Sinamin be used for itching?
Yes, this drug can be used for itching due to allergic reactions. However, it is important to consult your doctor before using this drug for itching.
How long can I take Sinamin for?
Sinamin is usually taken for a few days to a few weeks, depending on the severity of the allergy symptoms. If your symptoms persist for more than two weeks, it is important to consult your doctor.
Is Sinamin safe for long-term use?
Long-term use of Sinamin is generally not recommended, as it can cause side effects such as drowsiness, dizziness, nausea, confusion, and blurred vision. Consult your doctor before continuing to take this drug for an extended period of time.
Can I overdose on Sinamin?
Yes, it is possible to overdose on Sinamin. Signs of an overdose may include confusion, drowsiness, dizziness, nausea, flushing, headache, and vomiting. Seek medical attention immediately if you think you have overdosed.
Who should not take Sinamin?
This drug should not be taken by people who are allergic to any of the ingredients in it, people with narrow-angle glaucoma, people with urinary retention, or people with obstructive gastrointestinal conditions.
What should I do if I miss a dose of Sinamin?
Take the missed dose as soon as you remember it. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take extra doses to make up for a missed one.
Does Sinamin interact with any foods or other substances?
Yes, Sinamin may interact with certain foods and alcoholic beverages. It is important to consult your doctor before consuming highfat meals, grapefruit juice, alcoholic beverages, or other substances that may interact with this medication.
Are there any herbal or dietary supplements that I should avoid while taking Sinamin?
It is important to consult your doctor before taking any herbal or dietary supplements while taking this drug. Some herbal remedies or dietary supplements may increase the risk of side effects or interact with the medication.
What should I do if I experience any side effects while taking Sinamin?
If you experience any side effects, such as drowsiness, dizziness, nausea, loss of appetite, or blurred vision, stop taking Sinamin and contact your doctor or healthcare provider immediately.
Should I avoid any activities while taking Sinamin?
Yes, it is important to avoid activities that require alertness, such as driving, operating heavy machinery, or performing any other activities that are potentially dangerous. You should also avoid drinking alcohol while taking this medication, as it can increase the risk of side effects.
Does Sinamin cause dry mouth?
Yes, dry mouth is a common side effect of Sinamin. To reduce the risk of this side effect, it is important to drink plenty of fluids and to avoid any beverages that contain caffeine.
Is Sinamin available over the counter?
Yes, Sinamin is available over-the-counter in many countries. However, it is still important to consult your doctor before taking this medication.
How long should I wait before eating or drinking after taking Sinamin?
It is recommended to wait at least 30 minutes after taking Sinamin before eating or drinking. This will help ensure that the drug is fully absorbed into your system.
Is there a generic version of Sinamin?
Yes, Sinamin is available in generic form, which is much less expensive than the brand-name version.
Can Sinamin be used to treat asthma?
No, Sinamin is not recommended for the treatment of asthma. However, it can be used to treat allergic reactions that can lead to asthma symptoms.
What are the alternatives to Sinamin?
Other antihistamines that can be used instead of Sinamin include cetirizine, loratadine, desloratadine, and fexofenadine. Speak to your doctor to discuss which medication is best for your symptoms.
Can Sinamin be used for allergies to insect stings and bites?
Yes, Sinamin can be used to treat allergic reactions to insect stings and bites. However, make sure to consult your doctor before taking any medication for this type of reaction.
Can Sinamin reduce hives caused by allergies?
Yes, this medication can be used to reduce hives caused by allergies. It works by blocking the action of histamine, which is a substance in the body that causes hives.
Does Sinamin work for food allergies?
Yes, Sinamin can be used to treat allergic reactions to certain foods. However, it is important to speak to your doctor before taking any medication for this type of reaction.
Can Sinamin be used for eye allergies?
Yes, Sinamin can be used to treat eye allergies due to pollen, animal dander, or other airborne allergens. However, it is important to consult your doctor before taking this medication for eye allergies.
Can Sinamin be used for skin allergies?
Yes, this medication can be used to treat skin allergy symptoms such as rash and itching. However, make sure to consult your doctor before taking any medication for this type of reaction.
Can Sinamin be used for pet allergies?
Yes, this medication can be used to treat allergy symptoms caused by pet dander, such as nasal congestion and sneezing. However, make sure to consult your doctor before taking any medication for this type of reaction.
Is Sinamin safe for cats?
No, Sinamin is not recommended for cats as it can be toxic if administered in large amounts. Speak to your veterinarian if you think your cat may be experiencing allergies.
Can I take Sinamin with ibuprofin?
Yes, it is safe to take Sinamin with ibuprofen. However, if you experience any adverse reactions, be sure to seek medical attention immediately.
Can I take Sinamin with antibiotics?
Yes, it is safe to take Sinamin with antibiotics. However, if you experience any adverse reactions, be sure to seek medical attention immediately.
Will Sinamin help with nausea?
No, Sinamin is not recommended for the treatment of nausea. Consult your doctor for more effective treatments for nausea.