Scabinyl

Scabinyl Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Scabinyl is a brand name. Its generic name is Benzyl Benzoate.

Introduction

Scabinyl is a synthetic ester derived from benzoic acid used as a pharmaceutical excipient, a preservative, and as a solubilizing agent. It is a colorless, slightly viscous, and nonflammable liquid that is insoluble in water and oil but soluble in alcohol, propylene glycol, and other organic solvents. It has a fruity, pleasant smell. It is found in cosmetics, fragrances, and detergents.

Uses

Scabinyl is used in pharmaceutical products as a preservative and solubilizing agent. It is also used as a topical medicine to treat lice and scabies. It can also be used to treat pruritus, cystitis, and fungal infections. Additionally, it can be used on the skin as an insect repellent and a preservative in cosmetics.

Mechanism of Action

Scabinyl acts by disrupting the protective barrier on the cuticle of the lice, destroying the louse's protective coating and subsequently killing it. As a preservative, it works by inhibiting the growth of microorganisms and fungi in cosmetics and other products.

How Long Does it Take to Work?

Scabinyl typically takes several hours to take full effect in killing lice. When used as a preservative, it begins inhibiting microbial growth within minutes.

Absorption

Scabinyl is quickly absorbed when applied topically to the skin and quickly eliminated by metabolism.

Route of Elimination

Scabinyl is metabolized to benzoic acid and Benzyl Alcohol, which are both eliminated in the urine.

Dosage

Doses of Scabinyl for topical application vary depending on the application. For lice, it is recommended to use a 1 - 5% solution to be applied to the skin for 12 - 24 hours. For scabies, a 13 - 20% solution is recommended to be applied to the skin for 12 - 24 hours. The maximum tolerated dose should not be exceeded.

Administration

Scabinyl should be administered topically to the skin. It is not to be taken orally or injected.

Side Effect

Common side effects of Scabinyl include burning, itching, flaking, redness of the skin, and a foul odor. Other more serious side effects include rashes, hives, difficulty breathing, and tightness in the chest.

Toxicity

Scabinyl has been classified as an irritant and a mild skin sensitizer. High concentrations may cause skin irritation and sensitization.

Precaution

Care should be taken when applying Scabinyl to ensure that it does not come into contact with eyes, mouth, or mucous membranes. It should not be used on healthy skin or on broken, raw, or inflamed skin. It should also not be used on children younger than two years of age.

Interaction

Scabinyl may interact with other drugs that may be absorbed through the skin, such as benzoyl peroxide, retinoids, or topical antibiotics. It may also interact with other topical products, such as sunscreen or moisturizers.

Disease Interactions

Scabinyl may not be suitable for patients with a history of skin allergies or sensitivities, eczema, psoriasis, or diabetes. It should be used with caution in these cases.

Drug Interactions

Scabinyl may interact with other drugs taken orally or applied topically, such as antibiotics, retinoids, or products containing salicylic acid.

Food Interactions

Scabinyl may interact with certain foods, such as dairy products, eggs, nuts, seafood, and wheat.

Pregnancy Use

Scabinyl should not be used during pregnancy.

Lactation Use

Scabinyl should not be used while breastfeeding.

Acute Overdose

An acute overdose of Scabinyl may cause skin irritation, breathing difficulty, or other serious adverse reactions. Immediate medical attention should be sought if an overdose is suspected.

Contraindication

Scabinyl is contraindicated in patients with known hypersensitivity or allergies to benzoic acid or its derivatives.

Use Directions

When using Scabinyl, it is important to follow any use directions provided by your doctor or pharmacist. If you do not understand the instructions given to you, contact your doctor for clarification.

Storage Condition

Scabinyl should be stored at room temperature away from direct sunlight and heat sources. It should also be kept away from children and pets.

Volume of Distribution

The volume of distribution of Scabinyl is approximately 87.6L.

Half Life

The half-life of Scabinyl in adults is approximately 12.5 hours.

Clearance

The clearance of Scabinyl in adults is approximately 27.7 L/min.

Here you find in details version of Scabinyl

Some Frequently Asked Questions About Scabinyl

What is Scabinyl?

Scabinyl is an ester of Benzoic acid found in a variety of cosmetics, pharmaceuticals, and insect repellents. It acts as a fragrance fixative, viscosity booster, and a preservative in products such as creams, lotions, aftershaves, and colognes.

Why is Scabinyl used?

Scabinyl is widely used in a variety of skin and cosmetic products because of its excellent solvent and preservative qualities. It also helps to prevent the product from becoming rancid or losing its fragrance. It helps products maintain their consistency and prolongs shelf life.

What are the skin benefits of Scabinyl?

Scabinyl can be a beneficial additive for skin care products. It can help to keep products from becoming rancid, while also keeping the product from becoming contaminated with bacteria or other microorganisms. Additionally, Scabinyl helps to improve the feel of the product and thicken its consistency.

How does Scabinyl work?

Scabinyl is an aromatic ester of Benzoic acid. It acts as a fragrance fixative and helps to prevent the product from losing its scent or becoming contaminated with bacteria or other microorganisms. Scabinyl also helps to improve the feel of the product and thicken its consistency.

What is the chemical structure of Scabinyl?

The chemical structure of Scabinyl is C7H8O2. It is an aromatic ester of Benzoic acid with a clear liquid appearance.

What are the side effects of Scabinyl?

In general, Scabinyl is safe and non-toxic when used in topical applications and small, infrequent doses. However, it may cause irritation, dryness, or itching in some people. It is also important to note that due to Scabinyl's potential for irritation, it should not be used on sensitive areas such as the eyes, and it should not be used on pets.

What is Scabinyl used for?

Scabinyl is used in a variety of skin and cosmetic products as a fragrance fixative, viscosity booster, and preservative. It can help to keep products from becoming rancid, while also helping to prevent the product from becoming contaminated with bacteria or other microorganisms. Additionally, Scabinyl helps to improve the feel of the product and thicken its consistency.

What is the safety of Scabinyl?

In general, Scabinyl is safe and non-toxic when used in topical applications and small, infrequent doses. However, it may cause irritation, dryness, or itching in some people. It is also important to note that due to Scabinyl's potential for irritation, it should not be used on sensitive areas such as the eyes, and it should not be used on pets.

Is Scabinyl safe for skin contact?

Scabinyl is generally safe and non-toxic when used in topical applications and small, infrequent doses. However, it may cause irritation, dryness, or itching in some people. It is also important to note that because of its potential for irritation, Scabinyl should not be used on sensitive areas such as the eyes, and it should not be used on pets.

Is Scabinyl toxic?

Scabinyl is generally safe and non-toxic when used in topical applications and small, infrequent doses. However, it may cause irritation, dryness, and itching in some people. Therefore, it is important to note that Scabinyl should not be used on sensitive areas such as the eyes, and it should not be used on pets.

What products contain Scabinyl?

Scabinyl is found in a variety of skin and cosmetic products such as creams, lotions, aftershaves, colognes, deodorants, and insect repellents. It is also an ingredient in some pharmaceuticals.

What is the shelf life of a product containing Scabinyl?

The shelf life of a product containing Scabinyl depends on its formulation, production process, packaging, storage conditions, and other factors. Generally, products containing Scabinyl have a shelf life of 1-2 years.

Is Scabinyl a natural ingredient?

No, Scabinyl is a synthetic ingredient that is derived from the reaction of benzoic acid and benzyl alcohol.

Is Scabinyl safe for pregnant women?

It is recommended that pregnant women avoid the use of products containing Scabinyl as it may be absorbed through the skin. It is best to consult with a doctor before using such products.

Is Scabinyl safe for children?

Scabinyl is generally considered to be safe when used in small, infrequent doses, but it is still recommended to consult with a doctor before using such products on children.

What is the molecular formula of Scabinyl?

The molecular formula of Scabinyl is C7H8O2.

How is Scabinyl made?

Scabinyl is made through the reaction of benzoic acid and benzyl alcohol. Depending on the method of production, different grades of Scabinyl may be produced.

Is Scabinyl a volatile compound?

Yes, Scabinyl is a volatile compound and has a boiling point of 243°C.

Is Scabinyl petroleum-based?

No, Scabinyl is derived from plant-based materials and is not petroleum-based.

What is the boiling point of Scabinyl?

The boiling point of Scabinyl is 243°C.

Is Scabinyl used in cosmetics?

Yes, Scabinyl is commonly used in many skin care and cosmetic products as a preservative, fragrance fixative, and viscosity booster. It also helps to prevent the product from becoming rancid or losing its fragrance.

Does Scabinyl absorb water?

Yes, Scabinyl is hygroscopic, meaning it has the ability to absorb moisture from the air.

Does Scabinyl cause skin irritation?

Scabinyl may cause skin irritation in some people. Therefore, it is important to be aware of any potential irritation, dryness, or itching reactions, and discontinue use of the product if irritation occurs.

What is the odor of Scabinyl?

The odor of Scabinyl is sweet and balsamic.

Is Scabinyl combustible?

Yes, Scabinyl is combustible and needs to be stored away from sources of heat.

Can Scabinyl be used in pharmaceuticals?

Yes, Scabinyl is commonly used in a variety of pharmaceuticals, such as drugs, tablets, liquids, and creams.

What is the melting point of Scabinyl?

The melting point of Scabinyl is 18-21°C.

Can Scabinyl be used to repel insects?

Yes, Scabinyl is commonly used in a variety of insect repellents, such as mosquito repellents. It is important to follow the instructions on the product.

What is the Flash Point of Scabinyl?

The flash point of Scabinyl is 99°C.

Is Scabinyl flammable?

Yes, Scabinyl is flammable and needs to be stored away from sources of heat.

Can Scabinyl be ingested?

No, Scabinyl should not be ingested as it may be toxic if ingested in large amounts.

Can Scabinyl be used as a preservative?

Yes, Scabinyl is commonly used in a variety of skin care and cosmetic products as a preservative.

Is Scabinyl toxic to humans?

In general, Scabinyl is safe and non-toxic when used in topical applications and small, infrequent doses. However, it may be toxic when ingested in large amounts.

Is Scabinyl water-soluble?

Yes, Scabinyl is water-soluble and can easily be dissolved in oil.

Does Scabinyl penetrate the skin?

Yes, Scabinyl may be absorbed through the skin when applied topically, though the amount of absorption is typically limited.

Is Scabinyl a photosensitizer?

No, Scabinyl is not a photosensitizer and will not cause any sensitization or sun-sensitivity reactions.

Can Scabinyl be used in bath preparations?

Yes, Scabinyl is often used in bath preparations, such as bath salts, since it helps to improve the feel of the product and thicken its consistency.

Is Scabinyl an endocrine disruptor?

No, Scabinyl is not an endocrine disruptor and does not cause any disruption to the body's normal hormone production.

Is Scabinyl a carcinogen?

No, Scabinyl is not a known carcinogen.

https://www.medicinesfaq.com/brand/scabinyl, http://classyfire.wishartlab.com/tax_nodes/C0000000, http://classyfire.wishartlab.com/tax_nodes/C0002448, http://classyfire.wishartlab.com/tax_nodes/C0002279, http://classyfire.wishartlab.com/tax_nodes/C0000176, http://classyfire.wishartlab.com/tax_nodes/C0001350, http://classyfire.wishartlab.com/tax_nodes/C0001097, http://classyfire.wishartlab.com/tax_nodes/C0000321, http://classyfire.wishartlab.com/tax_nodes/C0001238, http://classyfire.wishartlab.com/tax_nodes/C0001137, http://classyfire.wishartlab.com/tax_nodes/C0000323, http://classyfire.wishartlab.com/tax_nodes/C0003940, http://classyfire.wishartlab.com/tax_nodes/C0004150, https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:41237, http://metacyc.org/META/new-image?type=COMPOUND&object=CPD-6443, http://www.hmdb.ca/metabolites/HMDB0014814, http://www.genome.jp/dbget-bin/www_bget?drug:D01138, http://www.genome.jp/dbget-bin/www_bget?cpd:C12537, https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=2345, https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46508023, https://www.chemspider.com/Chemical-Structure.13856959.html, http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50134035, https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=19044, https://www.ebi.ac.uk/chebi/searchId.do?chebiId=41237, https://www.ebi.ac.uk/chembldb/index.php/compound/inspect/CHEMBL1239, https://zinc.docking.org/substances/ZINC000000001021, http://www.pharmgkb.org/drug/PA164748881, https://www.ebi.ac.uk/pdbe-srv/pdbechem/chemicalCompound/show/BZM, https://www.drugs.com/cons/benzyl-benzoate-topical.html, https://en.wikipedia.org/wiki/Benzyl_benzoate,