Roxacine
Roxacine Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Roxacine is a brand name. Its generic name is Roxithromycin.
Roxacine Introduction
Roxacine is a semi-synthetic macrolide antibiotic used to treat bacterial infections. This drug belongs to a class of drugs known as macrolide antibiotics, which work by inhibiting the growth of bacteria. It is used to treat a wide range of bacterial infections, including respiratory infections, skin and ear infections, pneumonia, sexually transmitted infections (STIs), and other infections.
Uses for Roxacine
Roxacine is used to treat a wide range of bacterial infections, such as: respiratory infections, skin and ear infections, pneumonia, sexually transmitted infections (STIs), and other infections.
Mechanism of Action
Roxacine works by targeting the 50S ribosomal subunit of bacterial cell walls and inhibiting their growth, thereby preventing the spread of bacteria in the body.
How Long Does It Take to Work?
Roxacine starts working within a few days of taking the medication. It may take several weeks for the full effects of the drug to be felt.
Absorption
Roxacine is well absorbed from the gastrointestinal tract, with peak concentrations of the drug occurring 1 to 2 hours after ingestion. It is also absorbed via rectal administration, with peak concentrations of the drug being achieved 30 minutes after administration.
Route of Elimination
Roxacine is mainly eliminated via the kidneys and excreted in the urine. Some of the drug is eliminated via the bile and feces as well.
Dosage
The recommended adult dosage of Roxacine is 150 mg twice daily, taken on an empty stomach. The dosage for children aged 6 to 12 is 7.5 mg/kg twice daily and 3.5 mg/kg once daily for children aged 2 to 6. The dose for both adults and children may be adjusted depending on individual factors.
Administration
Roxacine is usually taken orally, either with water or on an empty stomach. It can also be administered rectally, with the dose being adjusted accordingly.
Side-Effect
Common side-effects of Roxacine include nausea, diarrhea, headache, dizziness, and abdominal pain. Other possible side-effects include, but are not limited to, rash, itching, hives, anemia, and liver problems.
Toxicity
Roxacine is generally well tolerated when used as prescribed. However, there is a risk of serious toxicity, including liver failure and renal failure, if the drug is taken in large doses or for prolonged periods of time. If any signs of toxicity occur, it is important to stop taking the drug immediately and contact your doctor.
Precautions
Before taking Roxacine, it is important to tell your doctor about any other drugs or supplements you are taking, as well as any allergies you may have. This drug should also not be taken if you have a history of liver or kidney disease, as it can make these conditions worse. Additionally, it is important to drink plenty of fluids while taking this medication.
Interactions
Roxacine is known to interact with certain drugs, such as antacids, anticoagulants, and certain antibiotics. It is important to tell your doctor about all the drugs and supplements you are taking in order to reduce the risk of interactions. Additionally, it is important to inform your doctor if you have a history of kidney or liver disease, as these drugs can interfere with the effectiveness of Roxacine.
Disease Interaction
Roxacine can interact with certain diseases, such as liver and kidney disease. It is important to tell your doctor about any chronic medical conditions you have before taking this medication.
Drug Interaction
Roxacine can interact with certain drugs, such as antacids, anticoagulants, and certain antibiotics. It is important to tell your doctor about all the drugs and supplements you are taking in order to reduce the risk of interactions. Additionally, it is important to inform your doctor if you have a history of kidney or liver disease, as these drugs can interfere with the effectiveness of Roxacine.
Food Interactions
Roxacine can interact with certain foods, such as dairy and other dairy products. It is important to ask your doctor about any dietary restrictions before taking this drug. Additionally, it is important to inform your doctor if you have a history of kidney or liver disease, as these drugs can interfere with the effectiveness of Roxacine.
Pregnancy Use
Roxacine is generally not recommended for use during pregnancy. It is important to tell your doctor if you are pregnant or planning to become pregnant before taking this medication.
Lactation Use
It is not known whether Roxacine is safe for use during lactation. It is important to tell your doctor if you are breastfeeding or planning to breastfeed before taking this medication.
Acute Overdose
An overdose of Roxacine can lead to serious side-effects, such as liver and kidney toxicity, and should only be taken as prescribed. If an overdose is suspected, it is important to seek medical attention immediately.
Contraindication
Roxacine should not be used by individuals with a known hypersensitivity to the drug or any of its components. Additionally, it is contraindicated in patients with a history of liver or kidney disease. It is also contraindicated in pregnant and breastfeeding women.
Use Direction
Roxacine should be taken as prescribed by your doctor and should not be taken in large doses or for prolonged periods of time. Additionally, it is important to take the medication with plenty of water.
Storage Conditions
Roxacine should be stored at a temperature between 15-30°C, away from heat and light. Additionally, it is important to keep the medication away from children and pets.
Volume of Distribution
The volume of distribution of Roxacine is approximately 0.77L/kg.
Half Life
The half-life of Roxacine is approximately 19 hours.
Clearance
Roxacine has a total clearance of approximately 0.3 mL/min/kg.
Here you find in details version of Roxacine
Some Frequently Asked Questions About Roxacine
What is Roxacine?
Roxacine is an antibiotic medicine used to treat a wide variety of bacterial infections. It belongs to the macrolide class of antibiotics which work by preventing bacteria from multiplying and spreading.
How does Roxacine work?
Roxacine works by stopping the growth of certain bacteria that cause infections. It does this by interfering with the production of proteins that are needed for bacterial growth and multiplication. By doing this, Roxacine stops the bacteria from spreading and causes the infection to resolve.
Can Roxacine be taken with other medications?
Yes, Roxacine can be taken with other medications. However, it is important to tell your doctor or pharmacist about any other medications you are taking and discuss any possible interactions. Certain other medications may increase or decrease the effectiveness of Roxacine.
What are some common side effects of Roxacine?
Some common side effects of Roxacine include nausea, vomiting, stomach pain, diarrhea, and headache. If any of these side effects become severe or if you experience any other side effects, contact your doctor or pharmacist immediately.
What should I do if I miss a dose of Roxacine?
If you miss a dose of Roxacine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your usual dosing schedule. Do not take a double dose to make up for a missed one.
How long does it take for Roxacine to work?
It usually takes about 1 to 2 days for Roxacine to start working. However, the amount of time it takes for the medication to work depends on the type and severity of the infection being treated.
What should I do if I overdose on Roxacine?
If you or someone else has overdosed on Roxacine, seek emergency medical attention immediately. Symptoms of an overdose may include nausea, vomiting, and stomach pain.
Is Roxacine safe for pregnant women?
Yes, Roxacine is generally considered safe for pregnant women. However, it is important to speak to your doctor about any potential risks before starting this medication. Your doctor will be able to decide if Roxacine is the right medication for you.
Can Roxacine be used to treat bacterial infections in children?
Yes, Roxacine can be used to treat bacterial infections in children. However, it is important to consult a doctor before giving this medication to a child. The doctor will be able to assess the risks and determine the correct dosage.
Can Roxacine be used to treat urinary tract infections?
Yes, Roxacine can be used to treat certain types of urinary tract infections. However, it is important to speak to your doctor before starting this medication to make sure that it is the right treatment for you.
What should I do if I experience any allergic reactions to Roxacine?
If you experience any signs of an allergic reaction to Roxacine, such as a rash, hives, swelling of the face, lips, tongue, or throat, or difficulty breathing, stop taking the medication immediately and speak to your doctor. You may need to be hospitalized if the reaction is severe.
Does Roxacine interact with any other medications?
Yes, Roxacine may interact with other medications. It is important to tell your doctor or pharmacist about all medications you are taking, including over-the-counter drugs and herbal supplements, as some medications may increase or decrease the effectiveness of Roxacine. Your doctor may also recommend a different medication.
What should I do if experience diarrhea while taking Roxacine?
If you experience diarrhea while taking Roxacine, it is important to stay hydrated and replenish your electrolytes. You may also take an over-the-counter medication to help stop the diarrhea. However, if your diarrhea persists or if it is accompanied by fever or blood, contact your doctor immediately.
Can Roxacine be used to treat sinus infections?
Yes, Roxacine can be used to treat certain types of sinus infections. However, it is important to speak to your doctor before starting this medication. Your doctor will assess the severity of your infection and be able to assess the appropriateness of Roxacine as a treatment option.
Can Roxacine be taken with alcohol?
No, it is not recommended to take Roxacine with alcohol. Drinking alcohol while taking Roxacine may increase the risk of certain side effects, including nausea, vomiting, and headaches.
Can Roxacine be used to treat skin infections?
Yes, Roxacine can be used to treat certain types of skin infections. However, it is important to speak to your doctor before starting this medication as there may be other options for treatment. Your doctor will be able to assess your infection and decide if Roxacine is the right medication for you.
What should I do if I experience joint pain while taking Roxacine?
If you experience joint pain while taking Roxacine, contact your doctor. Your doctor can assess the cause of your joint pain and suggest other medications or treatments if necessary.
Can Roxacine be used to treat sexually transmitted infections (STIs)?
Yes, Roxacine can be used to treat certain types of sexually transmitted infections. However, it is important to speak to your doctor before starting this medication. Not all STIs can be treated with Roxacine, and your doctor may recommend different treatment options depending on your particular situation.
What should I do if I experience nausea and vomiting while taking Roxacine?
If you experience nausea and vomiting while taking Roxacine, it is important to stay hydrated and replenish your electrolytes. You may also take an over-the-counter medication to help relieve your symptoms. However, if your symptoms persist or worsen, contact your doctor.
Can Roxacine be used to treat strep throat?
Yes, Roxacine can be used to treat strep throat. However, it is important to speak to your doctor before starting this medication. Your doctor will be able to assess the severity of your infection and be able to determine the most appropriate treatment.
Does Roxacine interact with birth control pills?
Yes, Roxacine can interact with some birth control pills. It is important to discuss any medications you are taking with your doctor and pharmacist. If you are taking birth control pills, your doctor may recommend an alternative medication or a different type of birth control.
What should I do if I experience dizziness while taking Roxacine?
If you experience dizziness while taking Roxacine, it is important to speak to your doctor. Your doctor may adjust your dosage or suggest another medication. Do not drive or operate heavy machinery if you are feeling dizzy.
Should I take Roxacine with food?
Yes, it is usually recommended to take Roxacine with food. Taking this medication with food may help to reduce the risk of stomach upset. It is also important to drink plenty of fluids while taking this medication.
Can Roxacine be used to treat bronchitis?
Yes, Roxacine can be used to treat certain types of bronchitis. However, it is important to speak to your doctor before starting this medication. Your doctor will assess the severity of your infection and be able to determine the most appropriate treatment.
Can Roxacine be used to treat strep throat in children?
Yes, Roxacine can be used to treat certain types of strep throat in children. However, it is important to speak to your doctor before giving this medication to a child. Your doctor will assess the severity of the infection and determine the most appropriate treatment.
What should I do if I experience headaches while taking Roxacine?
Headaches are a common side effect of taking Roxacine. If you experience headaches while taking this medication, it is important to speak to your doctor. Your doctor may recommend medications or treatments to help alleviate your symptoms.
Can Roxacine be used to treat gonorrhea?
Yes, Roxacine can be used to treat certain types of gonorrhea. However, it is important to speak to your doctor before starting this medication. Not all cases of gonorrhea can be treated with Roxacine, and your doctor may recommend other treatment options.
Does Roxacine have any interactions with other medications?
Yes, Roxacine may interact with other medications. It is important to tell your doctor or pharmacist about all medications you are taking, including over-the-counter drugs and herbal supplements, as some medications may increase or decrease the effectiveness of Roxacine. Your doctor may also recommend a different medication.
Can Roxacine be used to treat a uti?
Yes, Roxacine can be used to treat certain types of urinary tract infections. However, it is important to speak to your doctor before starting this medication to make sure that it is the right treatment for you.
What is the recommended dosage of Roxacine?
The recommended dosage of Roxacine varies depending on the type and severity of the infection being treated. It is important to speak to your doctor about the correct dosage for your particular situation.
What should I do if I experience an upset stomach while taking Roxacine?
If you experience an upset stomach while taking Roxacine, it is important to drink plenty of fluids and eat bland, easily digestible foods. You may also take an over-the-counter medication to help reduce stomach upset, such as an antacid. However, if your symptoms persist or worsen, contact your doctor.
Can Roxacine be used to treat ear infections?
Yes, Roxacine can be used to treat certain types of ear infections. However, it is important to speak to your doctor before starting this medication. Your doctor will assess the severity of your infection and be able to recommend the most appropriate treatment.
Is there anything I should avoid while taking Roxacine?
Yes, there are a few things you should avoid while taking Roxacine. Firstly, you should avoid taking other medications without first speaking to your doctor or pharmacist. You should also avoid drinking alcohol and avoid activities that require you to be alert, such as driving, if you experience any side effects.
Can Roxacine be used to treat bacterial infections in pets?
Yes, Roxacine can be used to treat certain types of bacterial infections in pets. However, it is important to speak to your veterinarian before giving this medication to your pet. Your veterinarian will assess the severity of the infection and be able to determine the most appropriate treatment for your pet.
Do I need to take Roxacine with food?
Yes, it is usually recommended to take Roxacine with food. Taking this medication with food may help to reduce the risk of stomach upset. It is also important to drink plenty of fluids while taking this medication.
What should I do if I experience nausea or vomiting while taking Roxacine?
If you experience nausea or vomiting while taking Roxacine, it is important to stay hydrated and replenish your electrolytes. You may also take an over-the-counter medication to help relieve your symptoms. However, if your symptoms persist or worsen, contact your doctor.
Can I take other medications while taking Roxacine?
Yes, other medications can be taken while taking Roxacine. However, it is important to tell your doctor or pharmacist about any other medications you are taking. Certain medications may interact with Roxacine and increase or decrease its effectiveness.