Rolacin

Rolacin Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Rolacin is a brand name. Its generic name is Clarithromycin.

Introduction

Clarthromycin is a type of antibiotic drug, used for treatment of many different bacterial infections. It belongs to the class of macrolide antibiotics, which work by interfering with bacterial protein synthesis.

Uses

Clarthromycin is used for treating a wide range of bacterial infections, such as ear infections, pneumonia, skin infections, urinary tract infections, tonsillitis, and some sexually transmitted disease. It is also used in some cases of Legionnaires' disease, sinusitis, and throat infections.

Mechanism of Action

Clarthromycin works by inhibiting bacterial protein synthesis. It does this by blocking the action of a bacterial enzyme called transpeptidase. This enzyme is responsible for constructing new proteins in the bacteria, which are required for the bacteria to survive and reproduce. By blocking the function of this enzyme, the drug is able to stop bacterial proliferation.

How Long Does it Take to Work?

Clarthromycin usually begins to take effect within 12-24 hours after it is taken. It may take up to 3 days to start feeling relief from the symptoms of the infection.

Absorption

Clarthromycin is typically well absorbed in the digestive tract, with an absorption rate of approximately 60%. It is also rapidly distributed in the tissues and bloodstream.

Route of Elimination

Clarthromycin is eliminated mainly unchanged in the urine. It is also eliminated in smaller amounts by the kidneys and gastrointestinal tract.

Dosage

Clarthromycin is available in generic and brand-name versions as 250 mg or 500 mg tablets. The usual recommended dosage is 250-500 mg twice daily. For severe infections, it is often recommended to be taken every 8 hours.

Administration

Clarthromycin should be taken with food or a glass of milk. It can also be taken with a full glass of water. It should be taken at the same time each day.

Side Effect

Common side effects of clarthromycin include nausea, diarrhea, vomiting, abdominal pain, dizziness, vertigo, headache, and rash. It may also cause liver damage in rare cases, which can lead to liver failure.

Toxicity

Clarthromycin is generally well tolerated. However, an overdose may lead to serious side effects such as seizures, coma, and liver failure. An overdose should be treated as soon as possible.

Precaution

Clarthromycin is not recommended for people who have had an allergic reaction to it before. It should also be used with caution in people with kidney or liver disease, and in people with a history of arrhythmia.

Interaction

Clarthromycin may interact with certain drugs, including antacids, vitamin/mineral supplements, warfarin, or drugs used to treat arrhythmias. It may also interact with other antibiotics, so it is important to check with your doctor before taking it.

Disease Interaction

Clarthromycin may interact with certain medical conditions, including arrhythmias, liver disease, or kidney disease. It may also interact with diseases such as HIV, tuberculosis, or any autoimmune diseases.

Drug Interaction

Clarthromycin may interact with certain drugs, such as antacids, vitamin/mineral supplements, warfarin, or drugs used to treat arrhythmias. It is important to check with your doctor before combining it with any other medications or supplements.

Food Interactions

Clarthromycin may interact with certain foods, such as dairy products, alcohol, or foods that are high in fat. It is important to check with your doctor before taking this medication with any foods.

Pregnancy Use

Clarthromycin is not recommended for pregnant women, as it may cause harm to the unborn baby. Women who are pregnant or breastfeeding should consult a doctor before taking this medication.

Lactation Use

Clarthromycin is not recommended for women who are breastfeeding, as it may pass into breast milk and cause harm to the baby. Women who are breastfeeding should consult a doctor before taking this medication.

Acute Overdose

An overdose of clarthromycin can lead to serious side effects, such as seizures, coma, and liver failure. If an overdose is suspected, it is important to seek medical attention as soon as possible.

Contraindication

Clarthromycin should not be taken by people who have had an allergic reaction to it before. It should also be avoided in people with liver disease and arrhythmias.

Use Direction

Clarthromycin should be taken as directed by your doctor. It is usually taken once or twice daily with food or a full glass of water.

Storage Condition

Clarthromycin should be stored in a cool, dry place away from light and humidity. It should be stored at room temperature.

Volume of Distribution

The volume of distribution of clarthromycin is approximately 0.4 L/kg.

Half Life

The half-life of clarthromycin is approximately 3-4 hours.

Clearance

The clearance of clarthromycin is approximately 1 ml/min/kg.

Here you find in details version of Rolacin

Some Frequently Asked Questions About Rolacin

What is Rolacin?

Rolacin is an antibiotic and is used to treat certain types of bacterial infections.

What is the generic name of Rolacin?

The generic name of Rolacin is Rolacin.

What are the common side effects of Rolacin?

Common side effects of Rolacin include nausea, vomiting, diarrhea, stomach upset, dizziness, headache, and skin rash.

Is Rolacin used to treat bronchitis?

Yes, Rolacin may sometimes be used to treat bronchitis, as it is an antibiotic and can help fight bacterial infections.

Does Rolacin treat urinary tract infections?

Yes, Rolacin may be an effective treatment for urinary tract infections caused by certain bacteria.

Can Rolacin be used to treat other illnesses?

Yes, Rolacin may be used to treat other conditions as determined by your doctor, such as strep throat, sinus infections, and skin infections.

What are the possible side effects of Rolacin?

Possible side effects of Rolacin include nausea, vomiting, diarrhea, stomach upset, headaches, dizziness, and skin rash.

Can Rolacin interact with other medications?

Yes, Rolacin can interact with other medications, including certain antibiotics, antidepressants, antifungals, and heart medications. It is important to discuss with your doctor any medications you are taking before taking Rolacin.

Can I drink alcohol while taking Rolacin?

No, it is not recommended to drink alcohol while taking Rolacin. Alcohol may increase the side effects of the medication and interfere with how the medication works.

How long does it take for Rolacin to work?

Rolacin begins to work within 24 hours of taking the medication. However, it may take several days for the full effect of the medication to be seen.

What should I do if I have an allergic reaction to Rolacin?

If you experience an allergic reaction to Rolacin, such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat, you should stop taking the medication and seek medical attention immediately.

Can Rolacin be taken with food?

Yes, Rolacin can be taken with food. It is also recommended to take Rolacin with a full glass of water and with a meal or snack.

What happens if I miss a dose of Rolacin?

If you miss a dose of Rolacin, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next dose at the regular time.

Is there anything I should avoid while taking Rolacin?

You should avoid taking antacids containing aluminum or magnesium within 2 hours before or after taking Rolacin. You should also avoid eating grapefruit or drinking grapefruit juice while taking the medication.

Can children take Rolacin?

Yes, Rolacin can be used in children, but only after consulting with a doctor. The dosage and length of treatment will depend on the child's weight and the severity of the infection.

Is Rolacin safe for pregnant women?

Yes, Rolacin is generally considered safe for pregnant women, unless otherwise advised by a doctor. It is important to discuss the risks and benefits of taking Rolacin with a doctor before taking the medication.

Does Rolacin cause drowsiness?

Rolacin may cause drowsiness or dizziness. It is important not to drive or operate heavy machinery until you know how Rolacin affects you.

Can Rolacin cause liver damage?

Yes, Rolacin can cause liver damage. It is important to contact a doctor immediately if you experience any signs of liver damage, such as nausea, vomiting, unusual tiredness, abdominal pain, dark urine, or yellowing of the eyes or skin.

Is Rolacin used to treat skin infections?

Yes, Rolacin can be used to treat skin infections caused by certain bacteria.

Can Rolacin cause hearing loss?

Yes, Rolacin can cause hearing loss and tinnitus. It is important to contact a doctor immediately if you experience any hearing loss or ringing in the ears while taking Rolacin.

Is Rolacin the same as Amoxicillin?

No, Rolacin and Amoxicillin are two different antibiotics. While both are used to treat bacterial infections, they are used to treat different types of infections.

Can Rolacin treat a urinary tract infection?

Yes, Rolacin can be an effective treatment for urinary tract infections caused by certain bacteria.

Should I take Rolacin on an empty stomach?

No, it is recommended to take Rolacin with a meal or snack and with a full glass of water.

Can Rolacin cause changes in blood sugar levels?

Yes, Rolacin can cause changes in blood sugar levels. It is important to monitor your blood sugar levels while taking Rolacin.

Does Rolacin treat strep throat?

Yes, Rolacin may be used to treat strep throat, depending on the severity of the infection.

Does Rolacin cause constipation?

Yes, Rolacin can cause constipation. It is important to hydrate and stay active while taking the medication.

How long does it take for Rolacin to clear up an infection?

The length of time it takes for Rolacin to clear up an infection will depend on the type of infection. However, it usually takes several days for the infection to improve.

Can I take Rolacin if I am allergic to penicillin?

Yes, Rolacin can be taken if you are allergic to penicillin. However, it is important to let your doctor know if you are allergic to penicillin before taking Rolacin.

Does Rolacin cause headaches?

Yes, Rolacin may cause headaches. If the headaches become severe or persistent, it is important to contact your doctor.

What should I do if I experience diarrhea while taking Rolacin?

If you experience diarrhea while taking Rolacin, it is important to drink plenty of fluids and rest. If the diarrhea persists or becomes worse, it is important to contact your doctor.

Can Rolacin be used to treat sinus infections?

Yes, Rolacin may be used to treat sinus infections caused by certain bacteria.

Should I take Rolacin with food?

Yes, it is recommended to take Rolacin with food and with a full glass of water.

Can Rolacin be used by elderly patients?

Yes, Rolacin can be used by elderly patients. However, it is important to discuss the risks and benefits of taking Rolacin with your doctor before taking the medication.

Does Rolacin cause dry mouth?

Yes, Rolacin can cause dry mouth. It is important to drink plenty of fluids while taking Rolacin.

Can Rolacin be taken with other medications?

Yes, Rolacin can be taken with other medications, but it is important to discuss any other medications you are taking with your doctor before taking Rolacin.

Is Rolacin used to treat ear infections?

Yes, Rolacin may be used to treat ear infections caused by certain bacteria.

Does Rolacin cause nausea?

Yes, Rolacin can cause nausea. If the nausea becomes severe or persistent, it is important to contact your doctor.

Can Rolacin cause heartburn?

Yes, Rolacin can cause heartburn. It is important to take the medication with food and to avoid lying down for at least 30 minutes after taking the medication.

Does Rolacin interact with any supplements?

Yes, Rolacin can interact with certain supplements. It is important to discuss any supplements you are taking with your doctor before taking the medication.

Can Rolacin cause loss of appetite?

Yes, Rolacin can cause loss of appetite. If the loss of appetite becomes severe or persists, it is important to contact your doctor.

Can Rolacin be used to treat strep throat?

Yes, Rolacin may be used to treat strep throat, depending on the severity of the infection.

Should I continue taking Rolacin even if I feel better?

Yes, it is important to continue taking Rolacin for the full duration of the treatment prescribed by the doctor, even if you feel better.