Remaquin

Remaquin Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Remaquin is a brand name. Its generic name is Primaquine.

Introduction

Remaquin is an antimalarial medication used to treat and prevent certain types of malaria. It is also used as a prophylaxis, which is used to prevent the further spread of malaria after initial treatment. Remaquin belongs to a group of antimalarials called 8-amino-quinolines.

Uses For

Remaquin is used to treat and prevent certain types of malaria caused by Plasmodium falciparum and Plasmodium vivax. It is also used as a prophylaxis (preventive medication) against further accusations of malaria in travelers in areas that are infected with Plasmodium vivax and Plasmodium falciparum. Remaquin should not be used in children under 8 years old.

Mechanism Of Action

Remaquin works by interfering with two essential proteins involved in the synthesis of DNA in the malaria parasite. It inhibits the enzyme dihydrofolate reductase and interferes with the electron transport system, both of which are essential for the parasite to survive. Remaquin also has a role in preventing the transmission of the malaria parasite to uninfected mosquito vectors.

How Long Does It Take To Work?

Remaquin usually takes effect within 1-2 hours of ingestion. The effects of Remaquin can last up to 48 hours, so it is important to take the medication as prescribed by a physician.

Absorption

Remaquin is absorbed quickly and completely from the gastrointestinal tract. It has an apparent volume of distribution of 1.31 L/kg and an apparent bioavailability of 42%.

Route Of Elimination

Remaquin is eliminated primarily by the kidneys. It has an elimination half-life of 23 hours.

Dosage

The recommended dosage for Remaquin depends on the condition being treated. For prophylaxis, the usual dosage is 15mg orally once daily for 7 days. For treatment of acute malaria, the usual dosage is 15mg orally once daily for 14 days. It is important to take Remaquin exactly as prescribed by a physician.

Administration

Remaquin should be taken with food or a full glass of water. It should be taken at the same time each day to maintain an even level of medication in the bloodstream.

Side Effects

The most common side effects of Remaquin include nausea, vomiting, headache, dizziness, loss of appetite, hair loss, hepatitis, rash, and anemia.

Toxicity

The toxic effects of Remaquin include changes in behavior, disorientation, difficulty breathing, and seizures.

Precautions

Before taking Remaquin, it is important to inform your physician if you have liver or kidney disease, blood disorders, glucose-6-phosphate dehydrogenase (G6PD) deficiency, or any allergies.

Interactions

Remaquin can interact with other drugs, including antacids, certain antibiotics, and nonsteroidal anti-inflammatory drugs (NSAIDs).

Disease Interactions

Remaquin can worsen certain diseases, including cancer, diabetes, anemia, and liver or kidney disease.

Drug Interactions

Remaquin can interact with certain drugs, including antacids, certain antibiotics, and nonsteroidal anti-inflammatory drugs (NSAIDs).

Food Interactions

It is important to take Remaquin with food to reduce the risk of interactions.

Pregnancy use

Remaquin should not be used in pregnant women, as it may cause serious birth defects.

Lactationuse

Remaquin should not be used while breastfeeding as it may be passed to the infant through breast milk.

Acute Overdose

The symptoms of an acute overdose may include severe abdominal pain, nausea, vomiting, seizures, and difficulty breathing. If you suspect an overdose, contact your local poison control center or emergency room immediately.

Contraindication

Remaquin should not be used in people with certain conditions, including porphyria, G6PD deficiency, severe anemia, and hemolytic anemia.

Use Direction

Remaquin should be taken as prescribed by a physician. Do not take more or less than the recommended amount.

Storage Condition

Remaquin should be stored in a cool, dry place, at room temperature. Keep out of reach of children and pets.

Volume Of Distribution

Remaquin has an apparent volume of distribution of 1.31 L/kg.

Half Life

Remaquin has an elimination half-life of 23 hours.

Clearance

Remaquin is eliminated primarily by the kidneys.

Here you find in details version of Remaquin

Some Frequently Asked Questions About Remaquin

What is Remaquin?

Remaquin is an antimalarial medication used to treat and prevent malaria infection.

How does Remaquin work?

Remaquin works by killing the malaria parasites in the liver. It also prevents the parasites from multiplying and spreading.

What is the active ingredient in Remaquin?

The active ingredient in Remaquin is primaquine phosphate.

How long does it take for Remaquin to work?

Remaquin typically begins to work within 24 hours of taking the medication.

What are the side effects of Remaquin?

Typical side effects of Remaquin include headache, nausea, dizziness, vomiting, loss of appetite, and abdominal pain.

Is Remaquin safe to take during pregnancy?

Remaquin should not be used during pregnancy, as it can cause harm to the unborn baby.

Is Remaquin safe for children?

Remaquin is generally not recommended for use in children under the age of 16.

Does Remaquin interact with other medications?

Yes, Remaquin can interact with other medications, including antacids, antibiotics, antivirals, and nonsteroidal anti-inflammatory drugs (NSAIDs).

What is the recommended dosage of Remaquin?

The recommended dosage of Remaquin is 0.5-1 tablet per day for adults and 0.25-0.5 tablet per day for children aged 16 and over.

What is the difference between Remaquin and chloroquine?

Remaquin is an antimalarial medication used to treat and prevent malaria infections, while chloroquine is an antimalarial medication used to treat and prevent malaria infections and also reduce inflammation in some autoimmune diseases.

Does Remaquin need to be taken with food?

It is recommended to take Remaquin with food to reduce the risk of stomach upset.

What should I do if I miss a dose of Remaquin?

If you miss a dose of Remaquin, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and take your next dose at the regular time.

How long should I take Remaquin?

The length of time that Remaquin should be taken depends on your individual medical condition. Your doctor will advise you on how long to take the medication.

Can I drink alcohol while taking Remaquin?

It is not recommended to drink alcohol while taking Remaquin, as it may increase the risk of side effects.

What is the generic name for Remaquin?

The generic name for Remaquin is primaquine phosphate.

Is Remaquin an antibiotic?

No, Remaquin is not an antibiotic; it is an antimalarial medication.

Can I buy Remaquin over the counter?

No, Remaquin is a prescription-only medication and cannot be bought over the counter.

Can Remaquin be used to treat other conditions?

No, Remaquin is only used to treat and prevent malaria infection.

What is the price of Remaquin?

The price of Remaquin varies depending on the manufacturer and dosage. Your pharmacy can provide you with the most up-to-date pricing information.

Can Remaquin cause liver damage?

Yes, Remaquin can cause liver damage in some individuals. If you have any liver problems, speak to your doctor before taking Remaquin.

Does Remaquin cause drowsiness?

Yes, Remaquin can cause drowsiness in some individuals. If you experience drowsiness, do not drive or operate machinery.

Does Remaquin interact with birth control?

Yes, Remaquin can interact with birth control. It is recommended to use another form of birth control while taking Remaquin.

Does Remaquin cause diarrhea?

Yes, Remaquin can cause diarrhea in some individuals.

Is Remaquin used to treat malaria?

Yes, Remaquin is used to treat and prevent malaria infection.

Does Remaquin cause weight gain?

No, Remaquin does not typically cause weight gain.

Can I take Remaquin with other medications?

It is important to tell your doctor about any other medications you are taking before taking Remaquin, as some medications can interact with Remaquin.

Will Remaquin work against all strands of malaria?

Remaquin has been shown to be effective against most strains of malaria; however, it may not work against all strains.

Does Remaquin cause loss of appetite?

Yes, Remaquin can cause loss of appetite in some individuals.

When should I start taking Remaquin?

Your doctor will advise you as to when you should start taking Remaquin. It is typically recommended to start taking the medication 1-2 days prior to traveling to a malaria-endemic region.

Is Remaquin safe to take if I have kidney problems?

Yes, Remaquin is generally considered safe to take if you have kidney problems; however, your doctor may need to adjust the dose or monitor your condition more closely.

Can I take Remaquin if I have high blood pressure?

Yes, Remaquin can be taken if you have high blood pressure; however, your doctor may need to adjust the dose or monitor your condition more closely.

Can I take Remaquin for longer than the recommended time?

No, Remaquin should only be taken for the recommended time, as it can cause serious side effects if taken for longer than recommended.

Can Remaquin be split in half?

Yes, Remaquin tablets can be safely split in half in order to reduce the dose taken.

What are the symptoms of an overdose on Remaquin?

Symptoms of an overdose on Remaquin may include headache, nausea, dizziness, vomiting, and abdominal pain.

Can Remaquin cause an allergic reaction?

Yes, Remaquin can cause an allergic reaction in some individuals. Stop taking the medication and seek medical attention if you experience any symptoms of an allergic reaction, such as rash, itching, or swelling.

Is Remaquin effective against Plasmodium falciparum malaria?

Yes, Remaquin has been found to be effective against Plasmodium falciparum malaria.

Does Remaquin cause hair loss?

No, Remaquin does not typically cause hair loss.

Can I take Remaquin if I'm breastfeeding?

No, Remaquin should not be taken while breastfeeding, as it can pass into breast milk and cause harm to the baby.

Does Remaquin need to be taken with food?

It is recommended to take Remaquin with food to reduce the risk of stomach upset.

What should I do if I get an upset stomach while taking Remaquin?

If you experience an upset stomach while taking Remaquin, try taking the medication with food. If your symptoms persist, speak to your doctor.

Does Remaquin cause drowsiness?

Yes, Remaquin can cause drowsiness in some individuals. If you experience drowsiness, do not drive or operate machinery.

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