Reglin
Reglin Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Reglin is a brand name. Its generic name is Rasagiline.
Introduction
Reglin is an anti-Parkinsonism drug and MAO-B inhibitor used to treat symptoms of Parkinson's disease such as muscle stiffness, tremors, and other movement-associated conditions. It is taken orally in form of tablets or capsules and can provide long-term relief from symptoms.Uses_for
Reglin is prescribed primarily for treating the symptoms of Parkinson’s disease. It is also used as an adjunct therapy in combination with other medications for improved efficacy. It is used to treat nerve damage and other symptoms associated with Parkinsons Disease, such as muscle stiffness, tremor, slowing of movement, and imbalance.Mechanism of Action
Reglin works by inhibiting an enzyme called monoamine oxidase type B (MAO-B). MAO-B is responsible for breaking down dopamine, a neurotransmitter involved in motor control. By blocking this enzyme, rasagiline is able to increase the level of dopamine in the brain, which can reduce the symptoms associated with Parkinson’s disease.How long does it take to work?
The effects of rasagiline usually become evident within one week after starting treatment. However, some people may experience relief of symptoms within the first few days, while others may take longer to experience its benefits.Absorption
Reglin is well absorbed following oral administration. Its peak plasma concentration is reached approximately 1.5 to 3 hours after ingestion.Route of Elimination
Reglin is metabolized in the liver and is rapidly excreted in the urine.Dosage
The recommended dose of rasagiline for adults is 1 mg once daily, with or without food. It should be taken in the morning and no more than one tablet should be taken per day. The dose can be increased to 2 mg per day after approximately 1-2 weeks, and this dosage may be better tolerated.Administration
Reglin should be taken orally, with or without food. Do not crush, break, or chew the tablets as it may alter the effects of the drug.Side_Effect
Common side effects of rasagiline include nausea, dizziness, headache, dry mouth, constipation, and redness of the skin. More serious side effects include blurred vision, agitation, confusion, and fever.Toxicity
High doses of rasagiline can produce toxicity, the signs and symptoms of which include confusion, agitation, headache, headache, vomiting, and seizures. If any of these signs appear, seek medical attention immediately.Precaution
Reglin is not recommended for pregnant or breast-feeding women without physician approval. It may cause harm if taken with certain other drugs or when combined with certain foods and beverages. Therefore, it is important to provide your doctor with a list of all medications that you are currently taking, including vitamins and herbal supplements.Interaction
Reglin may interact with other medications or supplements, so it is important to always discuss your other medications with your doctor. It should not be taken with MAO inhibitors or drugs that affect the central nervous system.Disease Interaction
Patients with liver or kidney dysfunction, uncontrolled narrow-angle glaucoma, or history of seizures should use rasagiline with caution.Drug Interaction
Reglin may interact with other drugs, so it is important to provide your physician with a list of all medications and doses that you are currently taking, including vitamins and herbal supplements. This includes drugs which increase blood pressure and those which affect the central nervous system.Food Interactions
Reglin must not be taken simultaneously with high-tyramine containing foods or beverages such as aged cheese, wines, smoked-fish, and certain fruits.Pregnancy Use
Reglin should not be used during pregnancy, as it may cause harm to the fetus.Lactation Use
Reglin is not recommended for use during lactation due to the potential risk of adverse effects in a nursing infant.Acute Overdose
An acute overdose of rasagiline can lead to severe dizziness, confusion, tremors, convulsions, rapid heartbeat, and low blood pressure. Prompt medical attention is necessary in such cases.Contraindications
Reglin is contraindicated in patients with narrow-angle glaucoma, history of seizures, known hypersensitivity to rasagiline, and in those taking other drugs that affect the central nervous system.Use Direction
Reglin should be taken as prescribed by your physician or pharmacist. The recommended starting dose is 1 mg per day with or without food. The dose may be increased to 2 mg per day after 4 weeks. It should not be crushed or chewed as this may alter the effects of the drug.Storage Conditions
Reglin should be stored in its original packaging at room temperature, away from heat and moisture. Protect from light and keep out of reach of children.Volume of Distribution
The volume of distribution of rasagiline is approximately 2.1 liters per kilogram.Half Life
The half-life of rasagiline is approximately 8 hours.Clearance
Reglin is metabolized and eliminated primarily by the liver. It has an estimated clearance of 33.4 liters per hour per kilograms.Here you find in details version of Reglin
Some Frequently Asked Questions About Reglin
What is Reglin?
Reglin is a medication taken to treat the symptoms of Parkinson's disease. It works by increasing levels of dopamine in the brain, which can help to improve the coordination and movement of people with Parkinson's disease.
Does Reglin have any serious side effects?
Yes, Reglin may have serious side effects such as insomnia, nausea, dizziness, and hallucinations. If you experience any of these symptoms, you should stop taking Reglin and contact your doctor immediately.
Is Reglin addictive?
No, Reglin is not considered to be an addictive medication.
What are the benefits of taking Reglin?
Reglin can help to improve the coordination and movement of people with Parkinson's Disease. It can also reduce the severity of some of the symptoms of Parkinson's Disease such as tremors and rigidity.
What is the recommended dosage for Reglin?
The recommended dosage for Reglin is 1 mg per day. Your doctor may adjust the dosage depending on how you respond to the medication.
When should I take Reglin?
Reglin is usually taken once a day, preferably after a meal.
How long does it take for Reglin to start working?
The effects of Reglin may take up to four weeks to become apparent. It is important to continue taking Reglin even if you don't feel any immediate effects.
Can I take Reglin with other medications?
It is important to always consult your doctor before taking any medications in combination with Reglin. Certain medications may interact with Reglin and cause serious side effects.
Can I take Reglin while pregnant?
It is not recommended to take Reglin while pregnant. If you are pregnant or planning on becoming pregnant, make sure to consult your doctor first.
Can I take Reglin while breastfeeding?
It is not recommended to take Reglin while breastfeeding as it can pass into breast milk. Talk to your doctor about the best option for you.
Can I drink alcohol while taking Reglin?
It is not recommended to drink alcohol while taking Reglin as it can increase the risk of side effects. Talk to your doctor if you wish to consume alcohol while taking Reglin.
Can I take Reglin with anti-depressants?
Yes, Reglin can be taken with most anti-depressant medications. However, it is important to consult your doctor before taking any medications in combination with Reglin.
Can I take Reglin with anti-anxiety medications?
Yes, Reglin can be taken with most anti-anxiety medications. However, it is important to consult your doctor before taking any medications in combination with Reglin.
Can I take Reglin with anti-psychotic medications?
Yes, Reglin can be taken with most anti-psychotic medications. However, it is important to consult your doctor before taking any medications in combination with Reglin.
Can I take Reglin with blood pressure medications?
Yes, Reglin can be taken with most blood pressure medications. However, it is important to consult your doctor before taking any medications in combination with Reglin.
Can I take Reglin with seizure medications?
Yes, Reglin can be taken with most seizure medications. However, it is important to consult your doctor before taking any medications in combination with Reglin.
Can I take Reglin with antibiotics?
Yes, Reglin can be taken with most antibiotics. However, it is important to consult your doctor before taking any medications in combination with Reglin.
Can I take Reglin with antihistamines?
Yes, Reglin can be taken with most antihistamines. However, it is important to consult your doctor before taking any medications in combination with Reglin.
Is Reglin covered by insurance?
This will depend on your individual insurance plan. Contact your insurance provider to find out if they cover Reglin.
How long should I keep taking Reglin?
You should continue taking Reglin until your doctor tells you to stop. Do not stop taking Reglin without talking to your doctor first.
What should I do if I miss a dose of Reglin?
If you miss a dose of Reglin, take it as soon as you remember. However, if it is almost time for your next dose, simply skip the missed dose and take your next dose on time.
Can I overdose on Reglin?
Yes, taking too much Reglin can be toxic and could cause serious side effects. If you think you may have taken too much Reglin, contact your doctor or poison control center right away.
Can I buy Reglin over-the-counter?
No, Reglin is not available over-the-counter. It can only be obtained with a prescription from your doctor.
How should I store Reglin?
Reglin should be stored at room temperature, away from moisture, heat, and direct light. Keep the medication out of reach of children and pets.
Can I get a generic version of Reglin?
No, there is no generic version of Reglin currently available.
Is a generic version of Reglin available in other countries?
No, at this time there is no generic version of Reglin available in any other countries.
How long does Reglin stay in the body?
Reglin has a half-life of approximately 8 hours. This means that it will take about 40 hours for it to be completely eliminated from the body.
Do I need to have regular blood tests while taking Reglin?
Your doctor may want you to have regular blood tests in order to monitor your blood levels while taking Reglin. Follow your doctor's instructions for any necessary laboratory tests.
Can I take Reglin with vitamins?
Yes, it is generally safe to take Reglin with vitamins. However, it is important to consult your doctor before taking any medications in combination with Reglin.
Can I take Reglin with herbal supplements?
Yes, it is generally safe to take Reglin with herbal supplements. However, it is important to consult your doctor before taking any medications in combination with Reglin.
Can I take Reglin with over-the-counter medications?
Yes, it is generally safe to take Reglin with over-the-counter medications. However, it is important to consult your doctor before taking any medications in combination with Reglin.
What are the possible drug interactions with Reglin?
Reglin can interact with certain medications, such as blood pressure medications and seizure medications. Make sure to tell your doctor about all medications you are taking in order to reduce the risk of drug interactions.
Can I take Reglin with non-steroidal anti-inflammatory drugs (NSAIDs)?
Yes, it is generally safe to take Reglin with non-steroidal anti-inflammatory drugs (NSAIDs). However, it is important to consult your doctor before taking any medications in combination with Reglin.
If I am taking Reglin, can I still drink caffeine?
Yes, you can still drink caffeinated beverages while taking Reglin. However, drinking too much caffeine can increase the risk of side effects, so it is best to stick to moderate amounts.
Will taking Reglin affect my ability to drive or operate machinery?
Reglin may cause dizziness or drowsiness, so it is important to avoid driving and operating machinery if you experience these symptoms.
Can I take an extra dose of Reglin if I am feeling very tired?
No, it is not recommended to take extra doses of Reglin. If you are feeling very tired, contact your doctor and do not take any extra doses of the medication.
Should I avoid any foods while taking Reglin?
You should avoid foods that are high in tyramine while taking Reglin, as they can interact with the medication and cause side effects. Examples of tyramine-rich foods include aged cheeses, cured meats, canned meats, and fermented fish.
Can I take a multivitamin while taking Reglin?
Yes, it is generally safe to take a multivitamin while taking Reglin. However, it is important to consult your doctor before taking any medications in combination with Reglin.