Refsu

Refsu, a brand name for a formulation containing essential Deflazacort, is widely used for various health benefits. This guide provides comprehensive information on the uses, dosage, side effects, and mechanism of action of Refsu, as well as insights into how long it takes to work. Understanding these aspects can help you make informed decisions about its use and effectiveness.

Introduction

Refsu is a synthetic glucocorticoid used to treat a variety of inflammatory and autoimmune conditions, such as rheumatoid arthritis, inflammatory bowel conditions, and asthma. It decreases inflammation and suppresses the immune system.

Uses

Refsu can be used to control inflammation and discomfort caused by a variety of diseases and conditions, including rheumatoid arthritis, lupus, asthma, inflammatory bowel disease, polymyalgia rheumatica, and other autoimmune conditions.

Mechanism of Action

Refsu acts by reducing levels of inflammation-causing chemicals in the body and by suppressing the immune system. It binds to certain glucocorticoid receptors in the cell nucleus that reduce inflammation.

How Long Does it Take to Work?

The effects of deflazacort may begin to be noticed within 1-2 weeks of beginning treatment, however it may take up to 6 weeks to reach its full anti-inflammatory effect.

Absorption

Refsu can be absorbed through the digestive system when taken orally.

Route of Elimination

Refsu is eliminated via the liver and kidneys in the form of metabolites.

Dosage

Refsu is available in oral tablets (6mg, 18mg, and 30mg) and an injectable form (10mg/mL). The recommended dose for adult for inflammatory and autoimmune conditions is 7.5-30mg per day, divided into 2-3 doses. The recommended dose for pediatric for inflammatory and autoimmune conditions is 0.3-1mg/kg per day, divided into 2-3 doses.

Administration

Refsu should be taken with food to increase its absorption. On days when you skip a dose, take your next dose at your regularly scheduled time.

Side Effects

The most common side effects of Refsu is weight gain, swelling, and acne. Other rare side effects may include stomach pain, headaches, dizziness, and insomnia.

Toxicity

Refsu is generally considered safe when used as instructed. However, long-term use can lead to serious side effects such as thinning of the bones (osteoporosis), high blood glucose levels, an increased risk of infection, and an increased risk of certain types of cancer.

Precautions

Patients taking Refsu should not stop taking it abruptly, as this can worsen symptoms. Patients should also not take more of this medication than prescribed. Common side effects such as acne may occur, however it is important to contact your doctor if more serious side effects develop.

Interactions

Refsu may interact with other medications such as antibiotics, antifungals, and immunosuppressants. It is important to tell your doctor about all medications you are taking.

Disease Interactions

Refsu is not recommended for use in people with diabetes, glaucoma, tuberculosis, or any other active infections.

Drug Interactions

Refsu can interact with other medications, such as antibiotics, antifungals, and immunosuppressants. It is important to tell your doctor about all medications you are taking.

Food Interactions

Refsu should be taken with food to increase its absorption.

Pregnancy Use

Refsu is categorized as pregnancy category C by the FDA. This means that the use of deflazacort during pregnancy is not recommended unless the potential benefit to the mother outweighs any potential risks to the fetus.

Lactation Use

It is not known whether Refsu passes into breastmilk. Therefore, breastfeeding is not recommended while taking this medication. Women should discuss any potential risks to their infant with their physician.

Acute Overdose

If an overdose is suspected, seek medical attention immediately. Symptoms may include weight gain, swelling, headaches, dizziness, and insomnia.

Contraindication

Refsu should not be used in people with known hypersensitivity to the drug or any of its components.

Use Direction

Take the dosage as recommended by your doctor. Do not take a larger dose or take it more often than prescribed. Do not stop taking it abruptly as this can worsen your condition.

Storage Condition

Store deflazacort tablets and injectable at room temperature.

Volume of Distribution

The volume of distribution of deflazacort is 17.3L.

Half Life

The half-life of deflazacort is 4-8 hours.

Clearance

The clearance of deflazacort is 66ml/min.

Here you find in details version of Refsu