Refain TR
Refain TR Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Refain TR is a brand name. Its generic name is Diclofenac.
Introduction
Refain TR is a nonsteroidal anti-inflammatory drug (NSAID). It works by blocking the production of certain natural substances that cause inflammation. Refain TR is used to treat pain and inflammation associated with various conditions, including arthritis, muscle sprains and strains, gout, painful menstrual periods, and migraine.
Uses
Refain TR is used to treat pain and inflammation associated with various conditions, including arthritis, muscle sprains and strains, gout, painful menstrual periods, and migraine.
Mechanism of Action
Refain TR works by blocking the production of certain natural substances that cause inflammation.
Absorption
Refain TR is absorbed rapidly and extensively with oral administration.
Route of Elimination
Refain TR is mainly eliminated by metabolism in the liver and to a small extent by excretion through the kidney.
Dosage
The recommended dose of diclofenac is 50-100mg, up to three times a day, depending on the condition and individual response. It is generally taken with food or milk to reduce stomach irritation.
Administration
Refain TR is available in various forms, including tablets, capsules, and topical gels, or liquid. It is generally taken by mouth with or without food.
Side Effects
Common side effects of diclofenac include nausea, vomiting, stomach upset, headache, dizziness, and drowsiness. Other more serious side-effects include an increased risk of stroke, heart attack, bleeding, and ulcers.
Toxicity
The onset of toxicity is usually at the 75mg dose. Symptoms may include drowsiness, confusion, dizziness, and nausea.
Precaution
Patients should not take diclofenac if they have a history of ulcers, or if they are taking other medications that may increase the risk of bleeding, such as warfarin, aspirin, or any other NSAIDs. In addition, it should be used with caution in patients with high blood pressure, kidney or liver disease, or heart failure.
Interaction
Refain TR should not be used with certain medications, including corticosteroids, diuretics, and warfarin. In addition, patients should avoid alcohol, as it can increase the risk of stomach irritation.
Disease Interaction
Refain TR should not be used in patients with certain diseases. These include stomach, kidney, or liver diseases, as well as bleeding disorders or heart failure.
Drug Interaction
Refain TR may interact with other medications, including antacids, lithium, and warfarin. Patients should talk to their doctor about any medications they are taking before beginning treatment with diclofenac.
Food Interactions
Refain TR should not be taken with food. Patients should make sure to take the medication with a full glass of water, and at least one hour before or two hours after meals.
Pregnancy Use
Refain TR should not be used during pregnancy, except if clearly necessary. If used, regular monitoring of the baby's condition is advised.
Lactation Use
Refain TR should not be used while breastfeeding, as it may pass into breast milk and affect the baby.
Acute Overdose
An overdose of diclofenac can be serious; symptoms may include nausea, vomiting, stomach pain, and dizziness. If an overdose is suspected, contact a doctor or poison control center immediately.
Contraindication
Refain TR should not be used in patients with known hypersensitivity to it, or to other NSAIDs. In addition, it should not be used in patients with bleeding disorders, or in patients with a history of ulcer or stomach bleeding.
Use Direction
Refain TR should be taken with food, or milk to reduce stomach irritation. It should not be used with alcohol.
Storage Condition
Refain TR should be stored at room temperature, and away from moisture and heat. It should be kept away from children and pets.
Volume of Distribution
The volume of distribution of diclofenac is 0.16 L/kg.
Half Life
The half-life of diclofenac is 1.2-2 hours.
Clearance
The clearance of diclofenac is 0.13-0.17 mL/min/kg.
Here you find in details version of Refain TR
Some Frequently Asked Questions About Refain TR
What is Refain TR?
Refain TR is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild to moderate pain, and help relieve symptoms of arthritis (osteoarthritis, rheumatoid arthritis, or juvenile arthritis) such as inflammation, swelling, stiffness, and joint pain.
What are the benefits of taking Refain TR?
Refain TR helps reduce inflammation and pain caused by arthritis and lowers fever. It may also help prevent damage to your joints caused by arthritis.
What are the side effects of taking Refain TR?
Common side effects of Refain TR include stomach pain, heartburn, nausea, vomiting, constipation, and dizziness. More serious side effects including bleeding, ulcers, and kidney and liver problems can also occur.
What should I tell my doctor before taking Refain TR?
Tell your doctor about all other medications you are taking, including over-the-counter medicines, vitamins, and supplements. You should also tell your doctor if you are pregnant, breastfeeding, or have any allergies.
Can I take Refain TR with other medications?
Refain TR can interact with other medications and should not be taken with some medications, including aspirin, ibuprofen, certain blood thinners, and medicines used to treat HIV or cancer. Always consult with your doctor before taking Refain TR with other medications.
What is the recommended dosage for Refain TR?
The recommended dose of Refain TR is 50 to 100 mg taken orally three or four times daily. The dose may be adjusted depending on the condition and response to treatment. Always take Refain TR exactly as prescribed by your doctor.
How long does it take for Refain TR to work?
The effects of Refain TR may be noticeable within one day or may take several days for full effects to be seen. Generally, people start to feel better within two weeks of starting the medication.
Can I take Refain TR if I am pregnant or breastfeeding?
Refain TR should be avoided in pregnant or breastfeeding women. Talk to your doctor before taking this medication if you are pregnant or breastfeeding.
Is Refain TR safe if I have heart failure?
Refain TR may worsen some of the symptoms of heart failure, so exercise caution if you have this condition. Consult with your doctor before taking this medication.
Is Refain TR a narcotic?
No. Refain TR is not a narcotic. It is a nonsteroidal anti-inflammatory drug (NSAID).
Can I take Refain TR with food?
Yes, you can take Refain TR with or without food. However, taking Refain TR with food may decrease the risk of stomach upset.
What if I miss a dose of Refain TR?
If you miss a dose of Refain TR, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.
Can Refain TR be taken long-term?
Refain TR can be taken long-term but should only be used as prescribed by your doctor. Talk to your doctor about any side effects that may occur if taking this medication for an extended period of time.
Can I drink alcohol while taking Refain TR?
You should avoid consuming alcohol while taking Refain TR. Alcohol can increase the risk of stomach irritation, bleeding, and other side effects.
What should I do if I experience side effects with Refain TR?
If you experience side effects with Refain TR, consult with your doctor. Your doctor may adjust your dose or suggest an alternate treatment. Do not adjust your dose or stop taking without consulting your doctor.
What is the generic name for Refain TR?
The generic name for Refain TR is diclofenac sodium.
What is the difference between diclofenac and ibuprofen?
Refain TR and ibuprofen are both nonsteroidal anti-inflammatory medications used to treat pain, inflammation, and fever. Ibuprofen is generally better tolerated than Refain TR; Refain TR can irritate the stomach and cause more side effects.
When should I take Refain TR?
Refain TR should be taken as prescribed by your doctor. Generally, the recommended dose is one pill taken three or four times daily after meals.
Does Refain TR have any interactions with other medications?
Yes, Refain TR can interact with some medications. It should not be taken with aspirin, ibuprofen, certain blood thinners, or medicines used to treat HIV or some types of cancer. Talk to your doctor about any other medications you are currently taking to avoid potential interactions.
Is Refain TR addictive?
No, Refain TR is not an addictive medication.
Is Refain TR the same as Naproxen?
No, Refain TR and Naproxen are two different medications. Naproxen is another nonsteroidal anti-inflammatory drug (NSAID) used to treat inflammation, pain, and fever.
How long should I stay on Refain TR?
The duration of Refain TR treatment will vary depending on your condition and response to treatment. Most people start to feel better within two weeks of starting the medication. Talk to your doctor about how long you will need to stay on Refain TR.
Can I take Refain TR if I have liver disease?
You should avoid taking Refain TR if you have liver disease. In some cases, using Refain TR can increase your risk of liver problems. Talk to your doctor before taking this medication.
Can Refain TR cause weight gain?
No, Refain TR does not typically cause weight gain. If you gain weight while taking Refain TR, consult with your doctor.
Can I use Refain TR for headaches?
No, Refain TR is not typically used for headaches. Talk to your doctor about other medications that are more effective for treating headaches.
Will Refain TR help me sleep better?
No, Refain TR is not typically used for sleep. If you are having difficulty sleeping, talk to your doctor about medications that are more effective for improving sleep.
Can I take Refain TR if I am breastfeeding?
No, Refain TR should be avoided in breastfeeding women. Talk to your doctor about other options for managing pain while breast-feeding.
Can Refain TR cause constipation?
Yes, Refain TR can cause constipation. If you experience constipation while taking Refain TR, talk to your doctor about treatment options.
Can I take Refain TR while pregnant?
No, Refain TR should be avoided in pregnant women. Talk to your doctor about other options for managing pain during pregnancy