Purifen
Purifen Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Purifen is a brand name. Its generic name is Dexibuprofen.
Introduction
Purifen is a non-steroidal anti-inflammatory drug (NSAID), which is used for relief of pain and inflammation. It belongs to the class of drugs called COX-2 inhibitors, which reduces pain and inflammation. Purifen was approved by the US FDA in July 2017.Uses
Purifen is used to treat moderate to severe pain, inflammation and stiffness associated with arthritis and musculoskeletal conditions such as bursitis, tendinitis, and joint pain. It is also used to treat headaches, menstrual cramps, and other common pains.Mechanism of Action
Purifen works by blocking the action of cyclooxygenase (COX), an enzyme involved in the production of substances called prostaglandins. Prostaglandins are responsible for causing inflammation, pain, and swelling. By blocking the enzyme, Purifen blocks the production of these prostaglandins, thereby reducing the pain and inflammation caused by the affected condition.How long does it take to work?
The effects of Purifen typically begin to take effect within 30 minutes to an hour after taking the drug. The drug may take up to 8 hours to show its full effects of relieving pain and inflammation.Absorption
Purifen is rapidly and almost completely absorbed from the gastrointestinal tract. The peak serum levels of the drug occur approximately 1-2 hours after oral administration.Route of Elimination
Purifen is metabolized in the liver and excreted in the urine and feces.Dosage
The typical recommended dosage of Purifen is 400 to 800 mg per day, taken orally in divided doses (usually, twice a day). The dose may be increased or decreased based on the patient’s response to the medication.Administration
Purifen is available in oral tablets and capsules, as well as in a liquid suspension. The tablets and capsules should be taken with a glass of water once or twice a day, as directed by the doctor. The liquid form of Purifen should be taken with food or after meals.Side Effect
Some of the common side effects of Purifen include nausea, vomiting, abdominal pain, indigestion, headache, dizziness, and diarrhea. Serious side effects such as bloody or black, tarry stools, chest pain, difficulty breathing, and weakness in the arms and legs have also been reported.Toxicity
High doses of Purifen can lead to severe liver or kidney damage and even cause death. Regular monitoring of liver function tests is recommended in patients taking Purifen. If any signs of liver or kidney damage appear, the dose of Purifen should be reduced or stopped immediately.Precautions
Purifen should be used with caution in patients with a history of asthma, stomach or intestinal ulcers, kidney or liver disease, bleeding disorders, or any other medical condition. It should not be used by pregnant women or those who are breastfeeding. People taking blood thinning medications should also avoid taking Purifen.Interactions
Purifen may interact with other medications, such as antacids, diuretics, ibuprofen, aspirin, anticoagulants, and other NSAIDs. It is important to tell your doctor about any other medications you are taking before taking Purifen.Disease Interaction
Purifen may interact with certain diseases, such as asthma, gastrointestinal ulcers, kidney or liver disease, or any other medical condition. People with these diseases should use Purifen with caution and monitor their condition closely.Drug Interactions
Purifen may interact with other medications, such as antacids, diuretics, ibuprofen, aspirin, anticoagulants, and other NSAIDs. It is important to tell your doctor about any other medications you are taking before taking Purifen.Food Interactions
Purifen may interact with certain foods, such as dairy products, alcohol, and spicy foods. It is best to avoid these foods while taking Purifen to minimize any potential interactions.Pregnancy Use
Purifen should be used with caution during pregnancy and should only be used if the potential benefits outweigh the risks to the baby. It is not recommended for pregnant women due to the potential for fetal damage or harm.Lactation Use
Purifen should not be used while breastfeeding as it can pass into breast milk.Acute Overdose
An overdose of Purifen can cause serious side effects, such as nausea, vomiting, abdominal pain, drowsiness, confusion, dizziness, fainting, respiratory depression, and death. If an overdose is suspected, seek medical attention immediately.Contraindication
Purifen should not be used in patients with a known hypersensitivity to ibuprofen or other NSAIDs. Patients with a history of asthma, stomach or intestinal ulcers, bleeding disorders, kidney or liver disease, or any other medical condition should also avoid using Purifen.Use Directions
Purifen should be taken exactly as prescribed by the doctor. The tablets and capsules should be taken with a full glass of water once or twice a day, as directed. The liquid form of Purifen should be taken with food or after meals.Storage Condition
Purifen should be stored at room temperature away from direct light and moisture. Keep it away from pets, children, and any other medicines.Volume of Distribution
Purifen has a volume of distribution of approximately 0.5 l/kg.Half Life
The half-life of Purifen is approximately 2-3 hours.Clearance
The clearance rate of Purifen is approximately 0.7 ml/min/kg.Here you find in details version of Purifen
Some Frequently Asked Questions About Purifen
What is Purifen?
Purifen is a nonsteroidal anti-inflammatory drug (NSAID) that is used to reduce symptoms of inflammation and pain.
What are the uses of Purifen?
Purifen is used to treat pain, inflammation, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and juvenile arthritis.
How should I take Purifen?
Purifen should be taken exactly as prescribed by your doctor. The usual adult dose is 200 to 400 mg every 4 to 6 hours.
Is Purifen safe?
Yes, Purifen is generally safe when taken as prescribed. However, like any medicine, there may be side effects or interactions with other medications.
Is Purifen habit-forming?
No, Purifen is not habit-forming and does not have any known abuse potential.
Are there any food or drink interactions with Purifen?
Yes, Purifen may interact with alcohol, caffeine, and certain foods. Therefore, it is important to check with your doctor or pharmacist before taking Purifen.
What are the possible side effects of Purifen?
Common side effects of Purifen include abdominal pain, diarrhea, nausea, and headache. More serious side effects can occur, so it is important to talk to your doctor if you experience any unusual symptoms while taking Purifen.
Does Purifen have any interactions with other medications?
Yes, Purifen may interact with some other medications, including aspirin, warfarin, and other NSAIDs. It is important to consult your doctor or pharmacist before taking any medications in combination with Purifen.
What is the maximum daily dose of Purifen?
The maximum daily dose of Purifen is 800 mg per day for adults. For children, the maximum daily dose is determined based on age and weight.
What is the difference between Purifen and ibuprofen?
Purifen is a newer, long-acting version of ibuprofen, with a longer duration of action in the body. Purifen is usually taken less frequently than ibuprofen, and is only available as a prescription medication.
Can pregnant or breastfeeding women take Purifen?
It is not recommended for pregnant or breastfeeding women to take Purifen. Women who are pregnant or breastfeeding should consult their doctor before taking any medication, including Purifen.
Is Purifen the same as aspirin or acetaminophen?
No, Purifen is not the same as aspirin or acetaminophen. Purifen is an NSAID, while aspirin and acetaminophen are not NSAIDs.
How does Purifen work?
Purifen works by blocking the production of certain chemicals in the body that cause inflammation and pain. This provides relief from the pain and inflammation associated with arthritis.
Can I take Purifen with other medications?
It is not recommended to take Purifen with certain other medications, such as aspirin, warfarin, or other NSAIDs. Consult your doctor or pharmacist before taking Purifen with any other medication.
How long does it take for Purifen to work?
It can take up to an hour for Purifen to start relieving pain and inflammation. The effects of Purifen can last for up to six hours.
In what form is Purifen available?
Purifen is available as a tablet, capsule, suspension, and injection. It is also available as an oral liquid for children.
How long does Purifen take to leave the body?
The half-life of Purifen is about 8 hours, so it takes an average of 24 to 36 hours for the drug to be completely eliminated from the body.
Can I buy Purifen over-the-counter?
No, Purifen is not available over the counter. It is only available by prescription from a doctor.
Is Purifen addictive?
No, Purifen is not an addictive drug and has no known abuse potential.
What happens if I take too much Purifen?
Taking too much Purifen can cause serious side effects like nausea, vomiting, stomach pain, drowsiness, headache, dizziness, or blurred vision. In some cases, it can even cause stomach or intestinal bleeding. If you take too much Purifen, you should seek immediate medical attention.
Can I take Purifen if I have liver or kidney problems?
It is not recommended for people with liver or kidney problems to take Purifen. People with liver or kidney problems should consult their doctor before taking any medication.
Can Purifen cause drowsiness?
Yes, Purifen can cause drowsiness or dizziness in some people. It is important to check with your doctor before taking Purifen if you are taking other medications that can cause drowsiness.
Does Purifen interact with other substances?
Yes, Purifen can interact with certain substances, such as alcohol, caffeine, and certain foods. It is important to discuss all medications and substances with your doctor before taking Purifen.
How long can I take Purifen safely?
It is not recommended to take Purifen for longer than 10 days without consulting a doctor. Taking Purifen for an extended period of time can increase the risk of serious side effects.
What should I do if I miss a dose of Purifen?
If you miss a dose of Purifen, take it as soon as you remember. Do not take two doses at once. If you take too much Purifen, seek immediate medical attention.
Is Purifen covered by insurance?
It depends. Most health insurance plans cover some or all of the cost of Purifen. Check with your insurance provider for details on your coverage.
Are there any long-term side effects of taking Purifen?
Long-term use of Purifen can increase the risk of stomach or intestinal bleeding, heart attack, stroke, and kidney damage. If you are taking Purifen for a prolonged period of time, it is important to talk to your doctor about the risks.
Does Purifen affect blood pressure?
Yes, Purifen can cause an increase in blood pressure. People with high blood pressure should consult their doctor before taking any medication, including Purifen.
Can children take Purifen?
Purifen is approved for use in children as young as 2 years old. The dose and form of Purifen used in children will be determined by the doctor and should be taken according to the doctor’s instructions.
Is Purifen a steroid?
No, Purifen is not a steroid. It is a nonsteroidal anti-inflammatory drug (NSAID).
What will happen if I stop taking Purifen suddenly?
It is not recommended to stop taking Purifen suddenly. If you need to stop taking Purifen, talk to your doctor about how to do so safely.
Can I take Purifen with food?
Yes, Purifen can be taken with or without food. However, it is important to follow your doctor’s instructions and not take more than the recommended dose.
What other medications can I take with Purifen?
It is important to talk to your doctor or pharmacist before taking any medications in combination with Purifen, as some medications can interact with it. Some medications that are safe to take with Purifen include acetaminophen, ibuprofen, and topical creams.
Can Purifen be used for headaches?
Yes, Purifen can be used for the temporary relief of headaches. If you experience frequent or severe headaches, it is important to talk to your doctor.
Does Purifen help with swelling?
Yes, Purifen is commonly used to reduce pain and swelling associated with conditions like osteoarthritis and rheumatoid arthritis.
Can I take Purifen if I have a history of stomach ulcers?
It is not recommended for people with a history of stomach ulcers to take Purifen. People with a history of stomach ulcers should talk to their doctor before taking any medication.
Can Purifen help with menstrual cramps?
Yes, Purifen can help to relieve pain associated with menstrual cramps. If menstrual cramps are severe or frequent, it is important to talk to a doctor.
Is Purifen suitable for people with allergies?
Yes, Purifen is suitable for people with allergies. People with allergies should check with their doctor before taking any medication, including Purifen.
Can I take Purifen with an antacid?
Yes, you can take Purifen with an antacid. However, it is important to take antacids at least two hours before or after taking Purifen to ensure maximum effectiveness.