Proquin
Proquin Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Proquin is a brand name. Its generic name is Primaquine.
Introduction
Proquin is an antimalarial medication used to treat and prevent certain types of malaria. It is also used as a prophylaxis, which is used to prevent the further spread of malaria after initial treatment. Proquin belongs to a group of antimalarials called 8-amino-quinolines.Uses For
Proquin is used to treat and prevent certain types of malaria caused by Plasmodium falciparum and Plasmodium vivax. It is also used as a prophylaxis (preventive medication) against further accusations of malaria in travelers in areas that are infected with Plasmodium vivax and Plasmodium falciparum. Proquin should not be used in children under 8 years old.Mechanism Of Action
Proquin works by interfering with two essential proteins involved in the synthesis of DNA in the malaria parasite. It inhibits the enzyme dihydrofolate reductase and interferes with the electron transport system, both of which are essential for the parasite to survive. Proquin also has a role in preventing the transmission of the malaria parasite to uninfected mosquito vectors.How Long Does It Take To Work?
Proquin usually takes effect within 1-2 hours of ingestion. The effects of Proquin can last up to 48 hours, so it is important to take the medication as prescribed by a physician.Absorption
Proquin is absorbed quickly and completely from the gastrointestinal tract. It has an apparent volume of distribution of 1.31 L/kg and an apparent bioavailability of 42%.Route Of Elimination
Proquin is eliminated primarily by the kidneys. It has an elimination half-life of 23 hours.Dosage
The recommended dosage for Proquin depends on the condition being treated. For prophylaxis, the usual dosage is 15mg orally once daily for 7 days. For treatment of acute malaria, the usual dosage is 15mg orally once daily for 14 days. It is important to take Proquin exactly as prescribed by a physician.Administration
Proquin should be taken with food or a full glass of water. It should be taken at the same time each day to maintain an even level of medication in the bloodstream.Side Effects
The most common side effects of Proquin include nausea, vomiting, headache, dizziness, loss of appetite, hair loss, hepatitis, rash, and anemia.Toxicity
The toxic effects of Proquin include changes in behavior, disorientation, difficulty breathing, and seizures.Precautions
Before taking Proquin, it is important to inform your physician if you have liver or kidney disease, blood disorders, glucose-6-phosphate dehydrogenase (G6PD) deficiency, or any allergies.Interactions
Proquin can interact with other drugs, including antacids, certain antibiotics, and nonsteroidal anti-inflammatory drugs (NSAIDs).Disease Interactions
Proquin can worsen certain diseases, including cancer, diabetes, anemia, and liver or kidney disease.Drug Interactions
Proquin can interact with certain drugs, including antacids, certain antibiotics, and nonsteroidal anti-inflammatory drugs (NSAIDs).Food Interactions
It is important to take Proquin with food to reduce the risk of interactions.Pregnancy use
Proquin should not be used in pregnant women, as it may cause serious birth defects.Lactationuse
Proquin should not be used while breastfeeding as it may be passed to the infant through breast milk.Acute Overdose
The symptoms of an acute overdose may include severe abdominal pain, nausea, vomiting, seizures, and difficulty breathing. If you suspect an overdose, contact your local poison control center or emergency room immediately.Contraindication
Proquin should not be used in people with certain conditions, including porphyria, G6PD deficiency, severe anemia, and hemolytic anemia.Use Direction
Proquin should be taken as prescribed by a physician. Do not take more or less than the recommended amount.Storage Condition
Proquin should be stored in a cool, dry place, at room temperature. Keep out of reach of children and pets.Volume Of Distribution
Proquin has an apparent volume of distribution of 1.31 L/kg.Half Life
Proquin has an elimination half-life of 23 hours.Clearance
Proquin is eliminated primarily by the kidneys.Here you find in details version of Proquin
Some Frequently Asked Questions About Proquin
What is Proquin?
Proquin is an antimalarial medication used to treat and prevent malaria infection.
How does Proquin work?
Proquin works by killing the malaria parasites in the liver. It also prevents the parasites from multiplying and spreading.
What is the active ingredient in Proquin?
The active ingredient in Proquin is primaquine phosphate.
How long does it take for Proquin to work?
Proquin typically begins to work within 24 hours of taking the medication.
What are the side effects of Proquin?
Typical side effects of Proquin include headache, nausea, dizziness, vomiting, loss of appetite, and abdominal pain.
Is Proquin safe to take during pregnancy?
Proquin should not be used during pregnancy, as it can cause harm to the unborn baby.
Is Proquin safe for children?
Proquin is generally not recommended for use in children under the age of 16.
Does Proquin interact with other medications?
Yes, Proquin can interact with other medications, including antacids, antibiotics, antivirals, and nonsteroidal anti-inflammatory drugs (NSAIDs).
What is the recommended dosage of Proquin?
The recommended dosage of Proquin is 0.5-1 tablet per day for adults and 0.25-0.5 tablet per day for children aged 16 and over.
What is the difference between Proquin and chloroquine?
Proquin is an antimalarial medication used to treat and prevent malaria infections, while chloroquine is an antimalarial medication used to treat and prevent malaria infections and also reduce inflammation in some autoimmune diseases.
Does Proquin need to be taken with food?
It is recommended to take Proquin with food to reduce the risk of stomach upset.
What should I do if I miss a dose of Proquin?
If you miss a dose of Proquin, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and take your next dose at the regular time.
How long should I take Proquin?
The length of time that Proquin should be taken depends on your individual medical condition. Your doctor will advise you on how long to take the medication.
Can I drink alcohol while taking Proquin?
It is not recommended to drink alcohol while taking Proquin, as it may increase the risk of side effects.
What is the generic name for Proquin?
The generic name for Proquin is primaquine phosphate.
Is Proquin an antibiotic?
No, Proquin is not an antibiotic; it is an antimalarial medication.
Can I buy Proquin over the counter?
No, Proquin is a prescription-only medication and cannot be bought over the counter.
Can Proquin be used to treat other conditions?
No, Proquin is only used to treat and prevent malaria infection.
What is the price of Proquin?
The price of Proquin varies depending on the manufacturer and dosage. Your pharmacy can provide you with the most up-to-date pricing information.
Can Proquin cause liver damage?
Yes, Proquin can cause liver damage in some individuals. If you have any liver problems, speak to your doctor before taking Proquin.
Does Proquin cause drowsiness?
Yes, Proquin can cause drowsiness in some individuals. If you experience drowsiness, do not drive or operate machinery.
Does Proquin interact with birth control?
Yes, Proquin can interact with birth control. It is recommended to use another form of birth control while taking Proquin.
Does Proquin cause diarrhea?
Yes, Proquin can cause diarrhea in some individuals.
Is Proquin used to treat malaria?
Yes, Proquin is used to treat and prevent malaria infection.
Does Proquin cause weight gain?
No, Proquin does not typically cause weight gain.
Can I take Proquin with other medications?
It is important to tell your doctor about any other medications you are taking before taking Proquin, as some medications can interact with Proquin.
Will Proquin work against all strands of malaria?
Proquin has been shown to be effective against most strains of malaria; however, it may not work against all strains.
Does Proquin cause loss of appetite?
Yes, Proquin can cause loss of appetite in some individuals.
When should I start taking Proquin?
Your doctor will advise you as to when you should start taking Proquin. It is typically recommended to start taking the medication 1-2 days prior to traveling to a malaria-endemic region.
Is Proquin safe to take if I have kidney problems?
Yes, Proquin is generally considered safe to take if you have kidney problems; however, your doctor may need to adjust the dose or monitor your condition more closely.
Can I take Proquin if I have high blood pressure?
Yes, Proquin can be taken if you have high blood pressure; however, your doctor may need to adjust the dose or monitor your condition more closely.
Can I take Proquin for longer than the recommended time?
No, Proquin should only be taken for the recommended time, as it can cause serious side effects if taken for longer than recommended.
Can Proquin be split in half?
Yes, Proquin tablets can be safely split in half in order to reduce the dose taken.
What are the symptoms of an overdose on Proquin?
Symptoms of an overdose on Proquin may include headache, nausea, dizziness, vomiting, and abdominal pain.
Can Proquin cause an allergic reaction?
Yes, Proquin can cause an allergic reaction in some individuals. Stop taking the medication and seek medical attention if you experience any symptoms of an allergic reaction, such as rash, itching, or swelling.
Is Proquin effective against Plasmodium falciparum malaria?
Yes, Proquin has been found to be effective against Plasmodium falciparum malaria.
Does Proquin cause hair loss?
No, Proquin does not typically cause hair loss.
Can I take Proquin if I'm breastfeeding?
No, Proquin should not be taken while breastfeeding, as it can pass into breast milk and cause harm to the baby.
Does Proquin need to be taken with food?
It is recommended to take Proquin with food to reduce the risk of stomach upset.
What should I do if I get an upset stomach while taking Proquin?
If you experience an upset stomach while taking Proquin, try taking the medication with food. If your symptoms persist, speak to your doctor.
Does Proquin cause drowsiness?
Yes, Proquin can cause drowsiness in some individuals. If you experience drowsiness, do not drive or operate machinery.