Pquin
Pquin Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Pquin is a brand name. Its generic name is Primaquine.
Introduction
Pquin is an antimalarial medication used to treat and prevent certain types of malaria. It is also used as a prophylaxis, which is used to prevent the further spread of malaria after initial treatment. Pquin belongs to a group of antimalarials called 8-amino-quinolines.Uses For
Pquin is used to treat and prevent certain types of malaria caused by Plasmodium falciparum and Plasmodium vivax. It is also used as a prophylaxis (preventive medication) against further accusations of malaria in travelers in areas that are infected with Plasmodium vivax and Plasmodium falciparum. Pquin should not be used in children under 8 years old.Mechanism Of Action
Pquin works by interfering with two essential proteins involved in the synthesis of DNA in the malaria parasite. It inhibits the enzyme dihydrofolate reductase and interferes with the electron transport system, both of which are essential for the parasite to survive. Pquin also has a role in preventing the transmission of the malaria parasite to uninfected mosquito vectors.How Long Does It Take To Work?
Pquin usually takes effect within 1-2 hours of ingestion. The effects of Pquin can last up to 48 hours, so it is important to take the medication as prescribed by a physician.Absorption
Pquin is absorbed quickly and completely from the gastrointestinal tract. It has an apparent volume of distribution of 1.31 L/kg and an apparent bioavailability of 42%.Route Of Elimination
Pquin is eliminated primarily by the kidneys. It has an elimination half-life of 23 hours.Dosage
The recommended dosage for Pquin depends on the condition being treated. For prophylaxis, the usual dosage is 15mg orally once daily for 7 days. For treatment of acute malaria, the usual dosage is 15mg orally once daily for 14 days. It is important to take Pquin exactly as prescribed by a physician.Administration
Pquin should be taken with food or a full glass of water. It should be taken at the same time each day to maintain an even level of medication in the bloodstream.Side Effects
The most common side effects of Pquin include nausea, vomiting, headache, dizziness, loss of appetite, hair loss, hepatitis, rash, and anemia.Toxicity
The toxic effects of Pquin include changes in behavior, disorientation, difficulty breathing, and seizures.Precautions
Before taking Pquin, it is important to inform your physician if you have liver or kidney disease, blood disorders, glucose-6-phosphate dehydrogenase (G6PD) deficiency, or any allergies.Interactions
Pquin can interact with other drugs, including antacids, certain antibiotics, and nonsteroidal anti-inflammatory drugs (NSAIDs).Disease Interactions
Pquin can worsen certain diseases, including cancer, diabetes, anemia, and liver or kidney disease.Drug Interactions
Pquin can interact with certain drugs, including antacids, certain antibiotics, and nonsteroidal anti-inflammatory drugs (NSAIDs).Food Interactions
It is important to take Pquin with food to reduce the risk of interactions.Pregnancy use
Pquin should not be used in pregnant women, as it may cause serious birth defects.Lactationuse
Pquin should not be used while breastfeeding as it may be passed to the infant through breast milk.Acute Overdose
The symptoms of an acute overdose may include severe abdominal pain, nausea, vomiting, seizures, and difficulty breathing. If you suspect an overdose, contact your local poison control center or emergency room immediately.Contraindication
Pquin should not be used in people with certain conditions, including porphyria, G6PD deficiency, severe anemia, and hemolytic anemia.Use Direction
Pquin should be taken as prescribed by a physician. Do not take more or less than the recommended amount.Storage Condition
Pquin should be stored in a cool, dry place, at room temperature. Keep out of reach of children and pets.Volume Of Distribution
Pquin has an apparent volume of distribution of 1.31 L/kg.Half Life
Pquin has an elimination half-life of 23 hours.Clearance
Pquin is eliminated primarily by the kidneys.Here you find in details version of Pquin
Some Frequently Asked Questions About Pquin
What is Pquin?
Pquin is an antimalarial medication used to treat and prevent malaria infection.
How does Pquin work?
Pquin works by killing the malaria parasites in the liver. It also prevents the parasites from multiplying and spreading.
What is the active ingredient in Pquin?
The active ingredient in Pquin is primaquine phosphate.
How long does it take for Pquin to work?
Pquin typically begins to work within 24 hours of taking the medication.
What are the side effects of Pquin?
Typical side effects of Pquin include headache, nausea, dizziness, vomiting, loss of appetite, and abdominal pain.
Is Pquin safe to take during pregnancy?
Pquin should not be used during pregnancy, as it can cause harm to the unborn baby.
Is Pquin safe for children?
Pquin is generally not recommended for use in children under the age of 16.
Does Pquin interact with other medications?
Yes, Pquin can interact with other medications, including antacids, antibiotics, antivirals, and nonsteroidal anti-inflammatory drugs (NSAIDs).
What is the recommended dosage of Pquin?
The recommended dosage of Pquin is 0.5-1 tablet per day for adults and 0.25-0.5 tablet per day for children aged 16 and over.
What is the difference between Pquin and chloroquine?
Pquin is an antimalarial medication used to treat and prevent malaria infections, while chloroquine is an antimalarial medication used to treat and prevent malaria infections and also reduce inflammation in some autoimmune diseases.
Does Pquin need to be taken with food?
It is recommended to take Pquin with food to reduce the risk of stomach upset.
What should I do if I miss a dose of Pquin?
If you miss a dose of Pquin, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and take your next dose at the regular time.
How long should I take Pquin?
The length of time that Pquin should be taken depends on your individual medical condition. Your doctor will advise you on how long to take the medication.
Can I drink alcohol while taking Pquin?
It is not recommended to drink alcohol while taking Pquin, as it may increase the risk of side effects.
What is the generic name for Pquin?
The generic name for Pquin is primaquine phosphate.
Is Pquin an antibiotic?
No, Pquin is not an antibiotic; it is an antimalarial medication.
Can I buy Pquin over the counter?
No, Pquin is a prescription-only medication and cannot be bought over the counter.
Can Pquin be used to treat other conditions?
No, Pquin is only used to treat and prevent malaria infection.
What is the price of Pquin?
The price of Pquin varies depending on the manufacturer and dosage. Your pharmacy can provide you with the most up-to-date pricing information.
Can Pquin cause liver damage?
Yes, Pquin can cause liver damage in some individuals. If you have any liver problems, speak to your doctor before taking Pquin.
Does Pquin cause drowsiness?
Yes, Pquin can cause drowsiness in some individuals. If you experience drowsiness, do not drive or operate machinery.
Does Pquin interact with birth control?
Yes, Pquin can interact with birth control. It is recommended to use another form of birth control while taking Pquin.
Does Pquin cause diarrhea?
Yes, Pquin can cause diarrhea in some individuals.
Is Pquin used to treat malaria?
Yes, Pquin is used to treat and prevent malaria infection.
Does Pquin cause weight gain?
No, Pquin does not typically cause weight gain.
Can I take Pquin with other medications?
It is important to tell your doctor about any other medications you are taking before taking Pquin, as some medications can interact with Pquin.
Will Pquin work against all strands of malaria?
Pquin has been shown to be effective against most strains of malaria; however, it may not work against all strains.
Does Pquin cause loss of appetite?
Yes, Pquin can cause loss of appetite in some individuals.
When should I start taking Pquin?
Your doctor will advise you as to when you should start taking Pquin. It is typically recommended to start taking the medication 1-2 days prior to traveling to a malaria-endemic region.
Is Pquin safe to take if I have kidney problems?
Yes, Pquin is generally considered safe to take if you have kidney problems; however, your doctor may need to adjust the dose or monitor your condition more closely.
Can I take Pquin if I have high blood pressure?
Yes, Pquin can be taken if you have high blood pressure; however, your doctor may need to adjust the dose or monitor your condition more closely.
Can I take Pquin for longer than the recommended time?
No, Pquin should only be taken for the recommended time, as it can cause serious side effects if taken for longer than recommended.
Can Pquin be split in half?
Yes, Pquin tablets can be safely split in half in order to reduce the dose taken.
What are the symptoms of an overdose on Pquin?
Symptoms of an overdose on Pquin may include headache, nausea, dizziness, vomiting, and abdominal pain.
Can Pquin cause an allergic reaction?
Yes, Pquin can cause an allergic reaction in some individuals. Stop taking the medication and seek medical attention if you experience any symptoms of an allergic reaction, such as rash, itching, or swelling.
Is Pquin effective against Plasmodium falciparum malaria?
Yes, Pquin has been found to be effective against Plasmodium falciparum malaria.
Does Pquin cause hair loss?
No, Pquin does not typically cause hair loss.
Can I take Pquin if I'm breastfeeding?
No, Pquin should not be taken while breastfeeding, as it can pass into breast milk and cause harm to the baby.
Does Pquin need to be taken with food?
It is recommended to take Pquin with food to reduce the risk of stomach upset.
What should I do if I get an upset stomach while taking Pquin?
If you experience an upset stomach while taking Pquin, try taking the medication with food. If your symptoms persist, speak to your doctor.
Does Pquin cause drowsiness?
Yes, Pquin can cause drowsiness in some individuals. If you experience drowsiness, do not drive or operate machinery.