Panadol Extra

Panadol Extra Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Panadol Extra is a brand name. Its generic name is Paracetamol + Caffeine.

Introduction

Panadol Extra is a combination drug used for different types of pain and to reduce fever. It belongs to the group of drugs called analgesics and antipyretics. It is an over-the-counter medication available in multiple forms such as tablets, capsules, liquids, suspensions and injections.

Uses of Panadol Extra

Panadol Extra is commonly used for relief from mild to moderate pain, such as headaches, muscle aches, dental pain, menstrual cramps, and flu. It is also used for reducing fever and as a nighttime sleep aid.

Mechanism of Action

Paracetamol is a centrally acting analgesic and antipyretic. It works by inhibiting the synthesis of substances called prostaglandins in the brain and spinal cord. These prostaglandins are involved in the transmission of pain signals to the brain. Caffeine works by constricting the blood vessels and increasing the pain threshold, thus decreasing the pain perception in the brain.

How Long Does It Take To Work?

Panadol Extra usually starts to work within 20-30 minutes when taken orally. Its effect can last up to 6 hours.

Absorption

Panadol Extra is rapidly and nearly completely absorbed from the gastrointestinal tract.

Route of Elimination

Panadol Extra is primarily eliminated through the kidneys, where it is metabolized to inactive metabolites which are then excreted in the urine.

Dosage

The usual dose of Panadol Extra is one or two tablets or capsules every 4-6 hours. The maximum dose in 24 hrs is 8 tablets or capsules. It is advised to not exceed the maximum dose as it can cause side effects.

Administration

Panadol Extra should be taken orally, with or without food. It can be taken with a glass of water.

Side Effect

• Nausea
• Vomiting
• Stomach pain
• Headache
• Dizziness
• Rash

Toxicity

Overdose of Panadol Extra can lead to serious side effects such as liver and kidney damage. Taking more than the recommended dose can also cause poisoning and can be fatal.

Precaution

• Patients with liver or kidney disease, asthma, high blood pressure, or heart diseases should not use Panadol Extra
• Women who are pregnant or breastfeeding should avoid the use of this medication.

Interaction

Panadol Extra can interact with other medications, such as anticoagulants and antidiabetic drugs, and increase the risk of side effects. It can also interact with alcohol and increases the risk of liver damage.

Disease Interaction

Panadol Extra can interact with certain conditions and worsen the symptoms, such as liver or kidney disease, asthma, high blood pressure, and heart diseases.

Drug Interaction

Panadol Extra can interact with other drugs and increase the risk of side effects. These drugs include anticoagulants, diuretics, and antidiabetic drugs.

Food Interactions

Foods such as alcohol, grapefruit juice, caffeine-containing drinks, and spicy foods may interact with Panadol Extra and increase the risk of side effects.

Pregnancy Use

Panadol Extra should be avoided during pregnancy, as its safety has not yet been established.

Lactation Use

It is not recommended to take Panadol Extra while breastfeeding, as its safety has not yet been established.

Acute Overdose

Acute overdose of Panadol Extra can cause severe symptoms such as nausea, vomiting, abdominal pain, drowsiness, sweating and confusion. It can also lead to liver and kidney damage.

Contraindication

Panadol Extra should not be taken in case of hypersensitivity to any of its components. Also, it is contraindicated in patients with certain medical conditions such as liver or kidney diseases, asthma, high blood pressure, and heart diseases.

Use Direction

As recommended by the doctor, Panadol Extra should be taken every 4-6 hours for relief from pain or fever. It can be taken with or without food.

Storage Condition

Panadol Extra should be stored at room temperature away from direct sunlight, moisture, and heat. Keep out of reach of children.

Volume of Distribution

The volume of distribution of Panadol Extra is not known.

Half Life

The half life of Panadol Extra is 3-4 hours.

Clearance

The clearance of Panadol Extra in the body is not known.

Here you find in details version of Panadol Extra

Some Frequently Asked Questions About Panadol Extra

What is Panadol Extra?

Panadol Extra is a combination of two over-the-counter medications used to relieve pain and fever. Paracetamol is an analgesic used to reduce the feeling of pain and Caffeine is a stimulant that can help improve alertness.

What are the most common side effects of Panadol Extra?

The most common side effects of Panadol Extra include nausea, drowsiness, headache, dizziness, restlessness, and confusion.

Can I take Panadol Extra if I am pregnant?

Pregnant women should not take Panadol Extra, unless it is prescribed by their doctor.

Is Panadol Extra safe to take for extended periods of time?

It is not recommended to take Panadol Extra for extended periods of time, as long-term use may lead to an increased risk of side effects and drug interactions.

Can I take Panadol Extra to help me stay awake?

No, it is not recommended to take Panadol Extra for the purpose of staying awake or increasing alertness.

What is the recommended dosage for Panadol Extra?

The recommended dosage for Panadol Extra is 500mg to 1000mg of paracetamol, and up to 200mg of caffeine.

Can I take Panadol Extra together with other medications?

Patients should consult their healthcare provider before taking Panadol Extra with other medications, as drug interactions may occur.

What are the most common drug interactions associated with Panadol Extra?

Drug interactions may include an increased risk of nausea, stomach pain, and appetite loss when taken with other medications such as birth control pills, antacids, and antibiotics. It is important to consult a healthcare provider before taking medications together.

Can I take Panadol Extra if I have Liver Disease?

Patients with liver damage or disease should not take Panadol Extra, as it can interfere with the body's ability to metabolize the active ingredients.

Can Panadol Extra cause stomach pain?

Panadol Extra can cause stomach pain, nausea, and vomiting if taken in high doses or if taken with other medications that can cause digestive issues.

How quickly does Panadol Extra start to work?

The effects of Panadol Extra start to take effect within one hour of taking the medication.

What is the maximum daily dose of Panadol Extra?

The maximum daily dose of Panadol Extra is not recommended beyond 2000mg of paracetamol and 400mg of caffeine.

Can I take Panadol Extra if I have a history of dehydration?

Patients with a history of dehydration should seek medical advice before taking Panadol Extra, as the caffeine may lead to dehydration.

What are the risks of taking too much Panadol Extra?

Risks of taking too much Panadol Extra include nausea, vomiting, confusion, fatigue, and liver damage. It is important to stick to the recommended dosage for best results.

What should I avoid while taking Panadol Extra?

Patients should avoid alcohol consumption while taking Panadol Extra, as it can increase the risk of side effects.

Can I combine Panadol Extra with other over-the-counter pain relievers?

It is not recommended to take Panadol Extra with other over-the-counter pain relievers as this increases the risk of side effects and drug interactions.

Can Panadol Extra cause addiction?

No, Panadol Extra is not known to cause addiction like other pain relievers.

Does Panadol Extra interact with other substances?

Panadol Extra may interact with certain substances, such as alcohol, tranquilizers and other medications, and cause an increased risk of severe side effects.

How often can I take Panadol Extra?

It is recommended to take no more than two doses of Panadol Extra in a 24-hour period, with at least 4 hours in between each dose.

How long does Panadol Extra stay in your system?

The active ingredients in Panadol Extra typically stay in your system for 4 to 6 hours.

Can I take Panadol Extra for a headache?

Yes, Panadol Extra can be taken for a headache. However, it is recommended to seek medical advice if the headache persists for more than 48 hours.

Can Panadol Extra cause insomnia?

Yes, Panadol Extra can cause insomnia if taken too close to bedtime.

Can I take Panadol Extra if I have asthma?

Patients with asthma should consult their healthcare provider before taking Panadol Extra, as the caffeine may trigger asthma symptoms.

Can I take Panadol Extra if I have a heart condition?

Patients with a heart condition should consult their healthcare provider before taking Panadol Extra, as the caffeine may cause an increase in heart rate and blood pressure.

Are there any natural alternatives to Panadol Extra?

Yes, there are many natural alternatives to Panadol Extra, such as ginger, turmeric, and capsaicin. Herbal teas such as chamomile and peppermint can also relieve pain and promote relaxation.

Can I take Panadol Extra if I am diabetic?

Patients with diabetes should consult their healthcare provider before taking Panadol Extra, as the caffeine may affect blood sugar levels.

What should I do if I take too much Panadol Extra?

If a patient takes too much Panadol Extra, they should seek medical advice immediately, as it can cause serious health issues including liver damage.

Can I take Panadol Extra for inflammation?

No, Panadol Extra is not recommended for the relief of inflammation.

Are there any foods that should be avoided while taking Panadol Extra?

It is recommended to avoid foods high in caffeine such as chocolate, tea, and coffee while taking Panadol Extra.

Can I take Panadol Extra if I have a stomach ulcer?

Patients with a stomach ulcer should consult their healthcare provider before taking Panadol Extra, as it may worsen the condition.

Are there any side effects associated with long-term use of Panadol Extra?

Yes, long-term use of Panadol Extra may cause an increased risk of side effects such as stomach pain, nausea, dizziness and liver damage.

Can I take Panadol Extra if I am breastfeeding?

It is not recommended to take Panadol Extra while breastfeeding, as the active ingredients may pass into breast milk and affect the baby.

Can I take Panadol Extra if I have high blood pressure?

Patients with high blood pressure should consult their healthcare provider before taking Panadol Extra, as the caffeine may affect blood pressure levels.

Is it safe to take Panadol Extra for a migraine?

No, it is not recommended to take Panadol Extra for a migraine, as it may not be effective.

What are the symptoms of an overdose of Panadol Extra?

Symptoms of an overdose of Panadol Extra may include nausea, vomiting, stomach pain, confusion, headache, and drowsiness.

Can I take Panadol Extra for a cold?

No, Panadol Extra is not recommended for the relief of cold symptoms.

Can I take Panadol Extra if I have kidney disease?

It is not recommended to take Panadol Extra if you have kidney disease, as the active ingredients may be difficult for the body to process.

Can I take Panadol Extra if I am allergic to aspirin?

It is not recommended to take Panadol Extra if you are allergic to aspirin, as the active ingredients may cause an allergic reaction.

Are there any foods that can increase the absorption of Panadol Extra?

Fatty foods such as fish, nuts, and avocados can help to increase the absorption of Panadol Extra in the body.

Can I take Panadol Extra if I have depression?

Patients with depression should consult their healthcare provider before taking Panadol Extra, as it may worsen the symptoms.

What is the difference between Paracetamol and Panadol Extra?

The main difference between Paracetamol and Panadol Extra is that Panadol Extra includes caffeine, which can help improve alertness and reduce fatigue.