Pacinac

Pacinac Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Pacinac is a brand name. Its generic name is Nepafenac.

Pacinac Introduction

Pacinac is a non-steroidal anti-inflammatory drug (NSAID) indicated for the treatment of inflammation and pain associated with ocular surgery. It is also approved for the treatment of postoperative inflammation and for the symptomatic treatment of pain associated with cataract extraction.

Uses for Pacinac

The primary uses for Pacinac are the prevention and treatment of postoperative inflammation and pain associated with ocular surgery. It is also used for the treatment of conditions such as iritis, chorioretinitis, and macular edema, as well as complications related to cataract extraction.

Mechanism of Action of Pacinac

Pacinac works by inhibiting the activity of cyclooxygenase (COX)-1 and COX-2, two enzymes involved in the body’s production of prostaglandins, substances that can cause inflammation, pain, and fever.

How Long does it Take for Pacinac to Work?

Pacinac typically begins to work within minutes, though its exact effects may vary depending on the condition being treated and the patient’s individual response.

Absorption of Pacinac

Pacinac is rapidly and well absorbed when applied to the eye. Its peak concentration in the eye is reached within 5 minutes after application.

Route of Elimination of Pacinac

Pacinac is rapidly metabolized in the ocular tissue and is primarily eliminated via the kidneys.

Dosage of Pacinac

Pacinac is available as an ophthalmic solution, 0.1% in a unit dose container for single use only. The recommended dosage is one drop in the affected eye three times a day, approximately 8 to 12 hours apart.

Administration of Pacinac

Pacinac should be applied to the affected eye in the form of an eye drop immediately before any type of ocular surgery. It should also be applied to the affected eye four times a day (approximately 8 to 12 hours apart) for up to two weeks after the surgery. Clean your hands and the affected eye with warm water and a mild soap before applying the drops. Apply gentle pressure to the inside corner of the eye (near the nose) for one to two minutes to prevent the medication from entering the tear duct and entering the rest of the body.

Side Effects of Pacinac

The most common side effects of Pacinac include: eye pain, itching, redness, increased intraocular pressure, and eye discharge. Less common side effects may include a allergic reaction, eye infection, blurred vision, increased sensitiviy to light, and dry eyes.

Toxicity of Pacinac

Pacinac is generally considered to be safe and well-tolerated. However, long-term use may lead to higher systemic absorption, and consequently, higher risk of serious adverse events.

Precaution of Pacinac

Pacinac should be used cautiously in patients with a known history of bleeding disorders, high blood pressure, or cardiac or renal disease. Patients should inform their physician of any concomitant medication they are taking before using Pacinac.

Interaction of Pacinac

Pacinac is known to interact with certain drugs including Vitamin C, anticoagulants, and diuretics. Pacinac may also interact with other NSAIDs, corticosteroids, and antibiotic medications.

Disease Interactions with Pacinac

Pacinac may interact with certain diseases, including bleeding disorders, high blood pressure, and renal or cardiac diseases. As Pacinac may cause increased systemic absorption, caution should be exercised when used in these patients.

Drug Interactions with Pacinac

Pacinac may interact with certain drugs, including anticoagulants, diuretics, Vitamin C, NSAIDs, and corticosteroids. It is important to tell your doctor about all medications you are taking before using Pacinac.

Food Interactions with Pacinac

Pacinac is not known to interact with any dietary foods. However, it is important to follow all dietary instructions given by your doctor while using the medication.

Pregnancy Use of Pacinac

Pacinac should be used with caution in pregnant women, as its safety in such patients has not been established. Tell your doctor if you are pregnant before using the medication.

Lactation Use of Pacinac

Pacinac should not be used by women who are breastfeeding as it is not known if the medication is passed through breast milk. Talk to your doctor before using Pacinac if you are breastfeeding.

Acute Overdose of Pacinac

Pacinac is not generally associated with acute overdose. However, if an overdose is suspected, contact a healthcare provider immediately additional medical advice.

Contraindication of Pacinac

Pacinac is contraindicated in patients with known hypersensitivity to any component of the drug. It should also not be used in patients with a confirmed diagnosis of an eye infection, corneal abrasion, or dermatitis of the eye.

Use Directions of Pacinac

When using Pacinac, patients should follow their doctor’s directions and any printed instructions supplied with the medication. Before using the medication, the eye should be washed with warm water and a mild soap to remove any debris.

Storage Condition of Pacinac

Pacinac should be stored at room temperature away from direct light and moisture. The medication should also be kept out of the reach of children.

Volume of Distribution of Pacinac

The volume of distribution of Pacinac is not known.

Half Life of Pacinac

The half-life of Pacinac is approximately 4 hours.

Clearance of Pacinac

The clearance of Pacinac is not known.

Here you find in details version of Pacinac

Some Frequently Asked Questions About Pacinac

What is Pacinac?

Pacinac is a nonsteroidal anti-inflammatory (NSAID) eye drop used to treat the pain and swelling associated with cataract surgery. It works by blocking the production of certain naturally occurring substances in the body that cause inflammation.

How does Pacinac work?

Pacinac works by blocking the production of certain naturally occurring substances in the body that cause inflammation. It is the only NSAID approved to be used after cataract surgery.

Who can use Pacinac?

Pacinac is for use only in adults after cataract surgery. It should not be used in children.

How often should I take Pacinac?

Pacinac is typically used every 8 to 12 hours, starting one day before your cataract surgery and continuing until the eye doctor or surgeon tells you to stop. Be sure to follow all instructions from your eye doctor or surgeon when using Pacinac.

What are the possible side effects of Pacinac?

Common side effects of Pacinac include eye irritation or burning, redness of the eye, blurred vision, scratchiness in the eyes, and eye discharge. If you experience any of these side effects, talk to your doctor.

Are there any precautions to take while using Pacinac?

You should not use Pacinac if you are allergic to any of its ingredients. Be sure to tell your doctor or eye doctor if you have a history of allergies, asthma, or any other serious medical conditions. Do not use more or less than recommended when taking Pacinac.

Can I use other eye medications in combination with Pacinac?

You should not use any NSAIDs, antibiotics, corticosteroids, or other prescribed medications in combination with Pacinac without first talking to your doctor. Additionally, do not use other eye drops while using Pacinac unless your doctor tells you to.

What should I do if I forget to take my dose of Pacinac?

If you miss a dose of Pacinac, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for the missed dose.

Should I avoid certain foods or drinks while using Pacinac?

No, there are no foods or drinks that you need to avoid while using Pacinac. However, you should not drink alcohol while using Pacinac as it can increase the risk of stomach bleeding.

Is there an alternative to Pacinac?

No, there is currently no alternative for Pacinac. However, your doctor may be able to prescribe you a similar medication that is more suitable for your condition.

What should I do if my eye irritation gets worse?

If your eye irritation gets worse while using Pacinac, talk to your doctor or eye doctor immediately as they may need to adjust your dose or switch you to a different medication.

Can I wear contacts while taking Pacinac?

No, it is recommended that you avoid wearing contacts while taking Pacinac. Pacinac may cause eye irritation or burning that could make wearing contacts uncomfortable.

Can Pacinac be used for pain or discomfort in my eye caused by allergies?

No, Pacinac is not recommended for the relief of pain or discomfort caused by allergies. You should consult your doctor to determine the best course of treatment for your allergy-related eye symptoms.

Is there any scientific evidence to support the use of Pacinac?

Yes, studies have shown that Pacinac may reduce pain and swelling associated with cataract surgery. Additionally, studies have also found that Pacinac may improve vision after cataract surgery.

What should I do if I experience an allergic reaction to Pacinac?

If you experience any signs of allergic reaction to Pacinac such as hives, difficulty breathing, or swollen eyes, you should immediately stop using Pacinac and seek medical attention.

Are there any foods or medications that interact with Pacinac?

You should not use other NSAIDs, antibiotics, corticosteroids, or other prescribed medications in combination with Pacinac without first talking to your doctor. Additionally, certain other medications such as oral corticosteroids, diuretics, and dihydroergotamine can also interact with Pacinac, so make sure to tell your doctor about all the medications you are taking.

Can I take Pacinac if I'm pregnant or breastfeeding?

No, Pacinac should not be used in pregnant or breastfeeding women unless explicitly directed to do so by a doctor. If you are pregnant or breastfeeding and need to take Pacinac, be sure to talk to your doctor about the potential risks.

Does Pacinac cause dry eye?

No, Pacinac does not typically cause dry eye. However, it may make existing dry eye symptoms worse, so tell your doctor if you are experiencing any dry eye symptoms before using Pacinac.

Does Pacinac cause drowsiness?

No, Pacinac does not typically cause drowsiness. However, if you experience any drowsiness after using Pacinac, you should talk to your doctor.

Can I wear eye makeup while using Pacinac?

Yes, you can wear eye makeup while using Pacinac. However, it is recommended to wait at least 15 minutes after applying Pacinac before applying makeup.

Can I go outside while using Pacinac?

Yes, you can go outside while using Pacinac. However, you should apply sunglasses to protect your eyes from the sun.

Can I swim while taking Pacinac?

Yes, you can swim while taking Pacinac. However, you should wear a swim cap to protect your eyes from the chlorine.

Can Pacinac be used for glaucoma?

No, Pacinac is not recommended for the treatment of glaucoma. You should consult your doctor to determine the best course of treatment for your glaucoma.

Can I take a shower or bath while using Pacinac?

Yes, you may take a shower or bath while using Pacinac. Just be sure to keep your eyes closed when showering or bathing to avoid getting Pacinac in your eyes.

Does Pacinac interact with any other drugs?

Yes, certain drugs such as oral corticosteroids, diuretics, and dihydroergotamine can interact with Pacinac, so be sure to tell your doctor about all the medications you are taking.

Will I experience any vision changes while taking Pacinac?

No, you should not experience any vision changes while taking Pacinac. However, if you do experience vision changes while taking Pacinac, you should talk to your doctor or eye doctor.

What should I do if my vision becomes blurred while using Pacinac?

If your vision becomes blurred while using Pacinac, you should talk to your doctor or eye doctor. Blurred vision is a possible side effect of Pacinac, and your doctor may need to adjust your dose or switch you to a different medication.

Can I use artificial tears while using Pacinac?

Yes, you can use artificial tears while using Pacinac. However, it is recommended to wait at least 15 minutes after applying Pacinac before using artificial tears.

Can I use eye drops containing preservatives while using Pacinac?

No, it is not recommended to use eye drops containing preservatives while using Pacinac. Preservatives can irritate the eyes, and could make using Pacinac uncomfortable.

Can I wear contact lenses while taking Pacinac?

No, it is recommended that you avoid wearing contact lenses while taking Pacinac. Pacinac may cause eye irritation or burning that could make wearing contacts uncomfortable.

Is there an age limit to using Pacinac?

Yes, Pacinac is for use only in adults after cataract surgery. It should not be used in children.

Will I need to use Pacinac for my entire cataract surgery recovery period?

No, you will not need to use Pacinac for your entire cataract surgery recovery period. Your doctor or eye doctor will determine when you can stop using Pacinac.

Can I use Pacinac if I have a history of epilepsy or seizure disorder?

No, it is not recommended to use Pacinac if you have a history of epilepsy or seizure disorder. Talk to your doctor before using any medications for pain or inflammation if you have a history of seizures or epilepsy.

Does Pacinac treat any other eye diseases?

No, Pacinac is not recommended for conditions other than pain and swelling associated with cataract surgery. You should consult your doctor to determine the best course of treatment for any other eye conditions.

Can my eye become infected while using Pacinac?

Yes, it is possible for your eye to become infected while using Pacinac. If you experience any signs of eye infection such as unusual pain, swelling, redness, or pus-like discharge, contact your doctor or eye doctor immediately.

Does Pacinac help to improve my vision?

Yes, studies have found that Pacinac may improve vision after cataract surgery. Additionally, Pacinac may also reduce pain and swelling associated with cataract surgery.

How long should I wait after using Pacinac before driving?

It is recommended to wait at least 15 minutes after applying Pacinac before driving. Pacinac may cause blurred vision, so it is important to give your eyes time to adjust before driving.

Can I use Pacinac if I have a history of stomach ulcers?

No, it is not recommended to use Pacinac if you have a history of stomach ulcers. Pacinac can irritate the stomach, and could make your ulcers worse. Talk to your doctor before using any medications for pain or inflammation if you have a history of stomach ulcers.

Can I get a prescription for Pacinac if I have an infection in my eye?

No, it is not recommended to use Pacinac if you have an infection in your eye. You should talk to your doctor immediately if you have an eye infection as you may need antibiotics or other medication to treat it.