P Phos

P Phos Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? P Phos is a brand name. Its generic name is Primaquine.

Introduction

P Phos is an antimalarial medication used to treat and prevent certain types of malaria. It is also used as a prophylaxis, which is used to prevent the further spread of malaria after initial treatment. P Phos belongs to a group of antimalarials called 8-amino-quinolines.

Uses For

P Phos is used to treat and prevent certain types of malaria caused by Plasmodium falciparum and Plasmodium vivax. It is also used as a prophylaxis (preventive medication) against further accusations of malaria in travelers in areas that are infected with Plasmodium vivax and Plasmodium falciparum. P Phos should not be used in children under 8 years old.

Mechanism Of Action

P Phos works by interfering with two essential proteins involved in the synthesis of DNA in the malaria parasite. It inhibits the enzyme dihydrofolate reductase and interferes with the electron transport system, both of which are essential for the parasite to survive. P Phos also has a role in preventing the transmission of the malaria parasite to uninfected mosquito vectors.

How Long Does It Take To Work?

P Phos usually takes effect within 1-2 hours of ingestion. The effects of P Phos can last up to 48 hours, so it is important to take the medication as prescribed by a physician.

Absorption

P Phos is absorbed quickly and completely from the gastrointestinal tract. It has an apparent volume of distribution of 1.31 L/kg and an apparent bioavailability of 42%.

Route Of Elimination

P Phos is eliminated primarily by the kidneys. It has an elimination half-life of 23 hours.

Dosage

The recommended dosage for P Phos depends on the condition being treated. For prophylaxis, the usual dosage is 15mg orally once daily for 7 days. For treatment of acute malaria, the usual dosage is 15mg orally once daily for 14 days. It is important to take P Phos exactly as prescribed by a physician.

Administration

P Phos should be taken with food or a full glass of water. It should be taken at the same time each day to maintain an even level of medication in the bloodstream.

Side Effects

The most common side effects of P Phos include nausea, vomiting, headache, dizziness, loss of appetite, hair loss, hepatitis, rash, and anemia.

Toxicity

The toxic effects of P Phos include changes in behavior, disorientation, difficulty breathing, and seizures.

Precautions

Before taking P Phos, it is important to inform your physician if you have liver or kidney disease, blood disorders, glucose-6-phosphate dehydrogenase (G6PD) deficiency, or any allergies.

Interactions

P Phos can interact with other drugs, including antacids, certain antibiotics, and nonsteroidal anti-inflammatory drugs (NSAIDs).

Disease Interactions

P Phos can worsen certain diseases, including cancer, diabetes, anemia, and liver or kidney disease.

Drug Interactions

P Phos can interact with certain drugs, including antacids, certain antibiotics, and nonsteroidal anti-inflammatory drugs (NSAIDs).

Food Interactions

It is important to take P Phos with food to reduce the risk of interactions.

Pregnancy use

P Phos should not be used in pregnant women, as it may cause serious birth defects.

Lactationuse

P Phos should not be used while breastfeeding as it may be passed to the infant through breast milk.

Acute Overdose

The symptoms of an acute overdose may include severe abdominal pain, nausea, vomiting, seizures, and difficulty breathing. If you suspect an overdose, contact your local poison control center or emergency room immediately.

Contraindication

P Phos should not be used in people with certain conditions, including porphyria, G6PD deficiency, severe anemia, and hemolytic anemia.

Use Direction

P Phos should be taken as prescribed by a physician. Do not take more or less than the recommended amount.

Storage Condition

P Phos should be stored in a cool, dry place, at room temperature. Keep out of reach of children and pets.

Volume Of Distribution

P Phos has an apparent volume of distribution of 1.31 L/kg.

Half Life

P Phos has an elimination half-life of 23 hours.

Clearance

P Phos is eliminated primarily by the kidneys.

Here you find in details version of P Phos

Some Frequently Asked Questions About P Phos

What is P Phos?

P Phos is an antimalarial medication used to treat and prevent malaria infection.

How does P Phos work?

P Phos works by killing the malaria parasites in the liver. It also prevents the parasites from multiplying and spreading.

What is the active ingredient in P Phos?

The active ingredient in P Phos is primaquine phosphate.

How long does it take for P Phos to work?

P Phos typically begins to work within 24 hours of taking the medication.

What are the side effects of P Phos?

Typical side effects of P Phos include headache, nausea, dizziness, vomiting, loss of appetite, and abdominal pain.

Is P Phos safe to take during pregnancy?

P Phos should not be used during pregnancy, as it can cause harm to the unborn baby.

Is P Phos safe for children?

P Phos is generally not recommended for use in children under the age of 16.

Does P Phos interact with other medications?

Yes, P Phos can interact with other medications, including antacids, antibiotics, antivirals, and nonsteroidal anti-inflammatory drugs (NSAIDs).

What is the recommended dosage of P Phos?

The recommended dosage of P Phos is 0.5-1 tablet per day for adults and 0.25-0.5 tablet per day for children aged 16 and over.

What is the difference between P Phos and chloroquine?

P Phos is an antimalarial medication used to treat and prevent malaria infections, while chloroquine is an antimalarial medication used to treat and prevent malaria infections and also reduce inflammation in some autoimmune diseases.

Does P Phos need to be taken with food?

It is recommended to take P Phos with food to reduce the risk of stomach upset.

What should I do if I miss a dose of P Phos?

If you miss a dose of P Phos, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and take your next dose at the regular time.

How long should I take P Phos?

The length of time that P Phos should be taken depends on your individual medical condition. Your doctor will advise you on how long to take the medication.

Can I drink alcohol while taking P Phos?

It is not recommended to drink alcohol while taking P Phos, as it may increase the risk of side effects.

What is the generic name for P Phos?

The generic name for P Phos is primaquine phosphate.

Is P Phos an antibiotic?

No, P Phos is not an antibiotic; it is an antimalarial medication.

Can I buy P Phos over the counter?

No, P Phos is a prescription-only medication and cannot be bought over the counter.

Can P Phos be used to treat other conditions?

No, P Phos is only used to treat and prevent malaria infection.

What is the price of P Phos?

The price of P Phos varies depending on the manufacturer and dosage. Your pharmacy can provide you with the most up-to-date pricing information.

Can P Phos cause liver damage?

Yes, P Phos can cause liver damage in some individuals. If you have any liver problems, speak to your doctor before taking P Phos.

Does P Phos cause drowsiness?

Yes, P Phos can cause drowsiness in some individuals. If you experience drowsiness, do not drive or operate machinery.

Does P Phos interact with birth control?

Yes, P Phos can interact with birth control. It is recommended to use another form of birth control while taking P Phos.

Does P Phos cause diarrhea?

Yes, P Phos can cause diarrhea in some individuals.

Is P Phos used to treat malaria?

Yes, P Phos is used to treat and prevent malaria infection.

Does P Phos cause weight gain?

No, P Phos does not typically cause weight gain.

Can I take P Phos with other medications?

It is important to tell your doctor about any other medications you are taking before taking P Phos, as some medications can interact with P Phos.

Will P Phos work against all strands of malaria?

P Phos has been shown to be effective against most strains of malaria; however, it may not work against all strains.

Does P Phos cause loss of appetite?

Yes, P Phos can cause loss of appetite in some individuals.

When should I start taking P Phos?

Your doctor will advise you as to when you should start taking P Phos. It is typically recommended to start taking the medication 1-2 days prior to traveling to a malaria-endemic region.

Is P Phos safe to take if I have kidney problems?

Yes, P Phos is generally considered safe to take if you have kidney problems; however, your doctor may need to adjust the dose or monitor your condition more closely.

Can I take P Phos if I have high blood pressure?

Yes, P Phos can be taken if you have high blood pressure; however, your doctor may need to adjust the dose or monitor your condition more closely.

Can I take P Phos for longer than the recommended time?

No, P Phos should only be taken for the recommended time, as it can cause serious side effects if taken for longer than recommended.

Can P Phos be split in half?

Yes, P Phos tablets can be safely split in half in order to reduce the dose taken.

What are the symptoms of an overdose on P Phos?

Symptoms of an overdose on P Phos may include headache, nausea, dizziness, vomiting, and abdominal pain.

Can P Phos cause an allergic reaction?

Yes, P Phos can cause an allergic reaction in some individuals. Stop taking the medication and seek medical attention if you experience any symptoms of an allergic reaction, such as rash, itching, or swelling.

Is P Phos effective against Plasmodium falciparum malaria?

Yes, P Phos has been found to be effective against Plasmodium falciparum malaria.

Does P Phos cause hair loss?

No, P Phos does not typically cause hair loss.

Can I take P Phos if I'm breastfeeding?

No, P Phos should not be taken while breastfeeding, as it can pass into breast milk and cause harm to the baby.

Does P Phos need to be taken with food?

It is recommended to take P Phos with food to reduce the risk of stomach upset.

What should I do if I get an upset stomach while taking P Phos?

If you experience an upset stomach while taking P Phos, try taking the medication with food. If your symptoms persist, speak to your doctor.

Does P Phos cause drowsiness?

Yes, P Phos can cause drowsiness in some individuals. If you experience drowsiness, do not drive or operate machinery.

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