Orlazid
Orlazid Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Orlazid is a brand name. Its generic name is Gliclazide.
Introduction
Orlazid (also known as glyburide) is an oral anti-diabetic medication used to treat type 2 diabetes. It works by encouraging the release of insulin and lowering the blood sugar levels. It may also be used for other conditions as determined by your doctor.Uses for
Orlazid is used to treat type 2 diabetes by helping to lower the blood sugar levels. It is usually prescribed after other diabetes medications have been tried without successful treatment of symptom.Mechanism of Action
Orlazid works to treat type 2 diabetes by increasing the effect of insulin, which signals the body to lower the blood sugar level. It can help control glucose levels by increasing the release of insulin and reducing the amount of sugar produced by the liver.How Long Does it Take to Work?
The duration of action of gliclazide is usually 6 to 12 hours, however it can take up to two weeks for it to reach its maximal effect.Absorption
Orlazid is rapidly absorbed in the gastrointestinal tract. It is mainly absorbed in the small intestine, with some absorption in the stomach.Route of Elimination
Orlazid is eliminated mainly through the kidneys. Approximately 70-90% of it is excreted unchanged in the urine.Dosage
For adults, the recommended starting dose is 30-60mg once daily before the morning meal. The dose can be increased by 30-60mg every 1-2 weeks until the desired blood sugar levels have been achieved. It is important to take the same amount and time of dose each day.Administration
Orlazid should be taken as directed by your doctor, usually once daily before a meal. It should be swallowed whole with a glass of water.Side Effect
Orlazid can cause side effects such as nausea, vomiting, dizziness, headache, blurred vision, paleness, stomach pain, loss of appetite, diarrhea, lightheadedness, fatigue, and constipation.Toxicity
Orlazid is considered to be a low toxicity medication. In case of overdose, symptomatic and supportive treatment should be provided.Precautions
Orlazid can interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.Interaction
Orlazid can interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.Disease Interaction
Orlazid may interact with certain diseases and conditions such as liver, kidney, or heart disease; thyroid disorders; and asthma. It is important to tell your doctor about all of your medical conditions before taking gliclazide.Drug Interactions
Orlazid may interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.Food Interactions
Orlazid can interact with certain foods and beverages and increase the risk of side effects. It is important to avoid foods high in sugar and fat while taking gliclazide.Pregnancy Use
Orlazid should not be used during pregnancy. Consult your doctor about the potential risks and benefits of taking gliclazide during pregnancy.Lactation Use
It is unknown whether gliclazide is excreted in breast milk. It is recommended to avoid taking gliclazide while breastfeeding.Acute Overdose
In case of an acute overdose of gliclazide, symptomatic and supportive treatment should be provided.Contraindication
Orlazid should not be used in patients with diabetic ketoacidosis, type 1 diabetes, type 3 diabetes, and in those allergic to it.Use Direction
Orlazid should be taken exactly as prescribed by your doctor. Do not increase or decrease the dose, or take the medication for a longer period of time than prescribed.Storage Conditions
Orlazid should be stored at room temperature, away from direct sunlight, heat and moisture. It should be kept out of the reach of children and pets.Volume of Distribution
The volume of distribution of gliclazide is approximately 20-50 L/kg.Half life
The elimination half-life of gliclazide is 1.5-4.5 hours.Clearance
The clearance of gliclazide in adults is 0.15-0.3 ml/min/kg.Here you find in details version of Orlazid
Some Frequently Asked Questions About Orlazid
What is Orlazid?
Orlazid is a medication which belongs to the group of medicines called sulfonylureas. It is used to control blood glucose levels in people with type 2 diabetes.
How does Orlazid work?
Orlazid works by increasing the amount of insulin that is released by the pancreas which helps to control blood glucose levels in people with Type 2 diabetes.
What are the uses of Orlazid?
Orlazid is used to control blood glucose levels in people with Type 2 diabetes.
What are the side effects of Orlazid?
Orlazid may cause some side effects, including headache, nausea, weight gain, tiredness, and some skin rashes.
Does Orlazid cause hypoglycemia?
Yes, Orlazid can cause hypoglycemia, which is a condition where the blood glucose levels become too low. Symptoms of hypoglycemia include sweating, hunger, shakiness, dizziness, and confusion.
How should Orlazid be taken?
Orlazid should be taken orally usually once or twice a day as directed by your doctor.
How long does it take for Orlazid to work?
Orlazid usually starts to work within 1-2 hours after it is taken.
Does Orlazid need to be taken with food?
No, Orlazid does not need to be taken with food. It can be taken before, with, or after meals.
What is the recommended dose of Orlazid?
The recommended dose of Orlazid depends on the individual and the type of diabetes. It is important to follow the instructions of your doctor or pharmacist.
What should I do if I forget to take Orlazid?
If you forget to take Orlazid, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose. Do not double your dose.
Should I avoid alcohol while taking Orlazid?
Yes, it is recommended to avoid alcohol while taking Orlazid as it can increase the risk of adverse effects such as low blood sugar.
Can Orlazid be taken while pregnant or breastfeeding?
Orlazid should not be taken while pregnant or breastfeeding. Speak to your doctor before taking any medication while pregnant or breastfeeding.
What foods should I avoid while taking Orlazid?
It is important to follow a healthy and balanced diet while taking Orlazid. Avoid foods high in sugar, fat, and cholesterol.
Is Orlazid available as a generic medication?
Yes, Orlazid is available as a generic medication.
What other medications should not be taken with Orlazid?
Certain medications can interact with Orlazid and should not be taken together. This includes ACE inhibitors, diuretics, sulfonamides, cimetidine, and other sulfonylureas.
Can I take Orlazid with metformin?
Yes, Orlazid can be taken with metformin. It is important to take both medications as prescribed by your doctor.
Are there any alternatives to Orlazid?
Yes, there are other medications available to control blood glucose levels. Speak to your doctor or pharmacist about other alternatives.
Can Orlazid be used to treat type 1 diabetes?
No, Orlazid is not suitable for use in people with type 1 diabetes.
Does Orlazid cause weight gain?
Orlazid can cause weight gain in some cases. It is important to follow a healthy and balanced diet and to exercise regularly.
What should I do if I experience side effects while taking Orlazid?
If you experience side effects while taking Orlazid, speak to your doctor or pharmacist. They may be able to suggest a change in dosage or medication to help alleviate the side effects.
Can diabetic ketoacidosis occur while taking Orlazid?
Yes, diabetic ketoacidosis can occur while taking Orlazid. Symptoms include dry mouth, thirst, fatigue, fruity odor on breath, and rapid breathing.
How should Orlazid be stored?
Orlazid should be stored at room temperature away from direct sunlight and heat. Do not keep Orlazid in the refrigerator or freezer.
Can I overdose on Orlazid?
Yes, it is possible to overdose on Orlazid. If you or someone you know has taken an overdose, call your local poison control center or emergency services immediately.
Can I donate blood while taking Orlazid?
No, it is recommended that you do not donate blood while taking Orlazid.
Can I take Orlazid if I have kidney disease?
It is recommended that you speak to your doctor before taking Orlazid if you have kidney disease. Your doctor may recommend a different medication.
Is Orlazid a blood thinner?
No, Orlazid is not a blood thinner. It is used to control blood glucose levels in people with Type 2 diabetes.
Can Orlazid be used to treat Type 1 diabetes?
No, Orlazid is not suitable for use in people with Type 1 diabetes.
Can Orlazid cause low blood pressure?
Yes, Orlazid can cause low blood pressure, which can cause dizziness, lightheadedness, and fainting.
Can I take Orlazid while taking other medications?
It is important to let your doctor know about all medications that you are taking before taking Orlazid. Certain medications can interact with Orlazid.
Does Orlazid raise cholesterol levels?
Yes, Orlazid can raise cholesterol levels. It is important to follow a healthy and balanced diet to help maintain healthy cholesterol levels.
Is Orlazid a steroid?
No, Orlazid is not a steroid. It is used to control blood glucose levels in people with Type 2 diabetes.
Does Orlazid cause diarrhea?
Yes, Orlazid can cause diarrhea. If you experience diarrhea while taking Orlazid, speak to your doctor or pharmacist.
Can I take Orlazid with ibuprofen?
It is recommended that you do not take Orlazid with ibuprofen as it may increase the risk of adverse effects. Speak to your doctor before taking any medications together.
Can I take Orlazid with muscle relaxers?
It is recommended that you do not take Orlazid with muscle relaxers as it may increase the risk of adverse effects. Speak to your doctor before taking any medications together.
What should I do if I miss a dose of Orlazid?
If you miss a dose of Orlazid, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose. Do not double your dose.
Can I take Orlazid while breastfeeding?
No, it is recommended that you do not take Orlazid while breastfeeding. Speak to your doctor before taking any medications while breastfeeding.
Can I take Orlazid while pregnant?
No, it is recommended that you do not take Orlazid while pregnant. Speak to your doctor before taking any medications while pregnant.
Can Orlazid cause headaches?
Yes, Orlazid can cause headaches in some people. If you experience headaches while taking Orlazid, speak to your doctor or pharmacist.
Can I take Orlazid with other diabetes medications?
Yes, Orlazid can be taken with other diabetes medications. It is important to follow the instructions of your doctor or pharmacist.
What should I do if I experience low blood sugar while taking Orlazid?
If you experience low blood sugar while taking Orlazid, it is important to eat or drink something sugary, such as fruit juice, honey, candy, or a glucose tablet. It is also important to speak to your doctor or pharmacist.
Are there any foods that I should avoid while taking Orlazid?
It is important to follow a healthy and balanced diet while taking Orlazid. Avoid foods high in sugar, fat, and cholesterol.
How long can I take Orlazid for?
The length of time that you take Orlazid for depends on the individual and the type of diabetes. It is important to follow the instructions of your doctor or pharmacist.
Is Orlazid a controlled substance?
No, Orlazid is not a controlled substance.