Orextil

Orextil Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Orextil is a brand name. Its generic name is Cefuroxime.

Introduction

Orextil is an antibiotic of the cephalosporin class used to treat a variety of bacterial infections. It can be used to treat a wide range of infections including skin and soft tissue infections, respiratory infections, urinary tract infections, sexually transmitted infections, and bone and joint infections.

Uses For

Orextil is used to treat a variety of bacterial infections, including skin and soft tissue infections, respiratory infections, urinary tract infections, sexually transmitted infections, and bone and joint infections.

Mechanism of Action

Orextil works by inhibiting the growth of bacteria by interfering with the bacterial cell wall synthesis. This prevents the bacteria from being able to replicate and leads to the eventual death of the bacteria.

How Long Does It Take To Work?

Orextil typically begins to work within 48 hours of taking it, and symptoms should improve during that time. It is important to finish the full course of medication to prevent the re-emergence of the infection. If symptoms have not improved after 48 hours, contact your doctor.

Absorption

Orextil is absorbed rapidly from the gastrointestinal tract and reaches peak concentrations in various organs and tissues, including the lungs, kidneys, prostate , and central nervous system.

Route of Elimination

Orextil is eliminated mainly via the kidneys. It is also metabolized in the liver and excreted in the bile.

Dosage

The dosage of cefuroxime varies according to the infection being treated and the patient's age and weight. Generally, it is given as a single dose or in two divided doses given every 12 hours. For adults, the dosage ranges from 125 mg to 500 mg taken orally every 8 to 12 hours. For children, the dosage may be lower. It is important to follow your doctor's instructions.

Administration

Orextil is usually taken orally. It can also be given intravenously, depending on the condition being treated. For oral administration, it is usually taken with a full glass of water. It can be taken with or without food.

Side Effect

Common side effects associated with cefuroxime include nausea, vomiting, stomach pain, diarrhea, headache, dizziness, rash, itching, and vaginal itching and discharge.

Toxicity

Orextil is generally safe and well tolerable at recommended doses. However, it can cause certain toxic side effects when taken in high doses, including seizures, tremors, coma, and death.

Precautions

Orextil should not be used in patients with a known allergy or hypersensitivity to cefuroxime, other cephalosporins, or penicillins. Orextil should be used with caution in patients with a history of liver or kidney disease, or in those who are pregnant or breastfeeding.

Interaction

Orextil can interact with other medications, including non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, warfarin (blood thinners), and certain antibiotics. Before taking cefuroxime, it is important to tell your doctor about any other medications you are taking to avoid potential interactions.

Disease Interactions

Orextil can interact with certain diseases that can affect its efficacy. These include certain liver and kidney disease, diseases of the immune system, and conditions that affect the gastrointestinal tract. It is important to tell your doctor if you have any of these conditions before taking cefuroxime.

Drug Interactions

Orextil can interact with certain medications, including other antibiotics, anticoagulants (blood thinners), nonsteroidal anti-inflammatory drugs (NSAIDs), warfarin, and probenecid. It is important to tell your doctor about all medications you are taking.

Food Interactions

Orextil may interact with certain foods. It should be taken at least two hours before or after taking calcium, magnesium, or iron supplements or antacids. Also, avoid alcohol while taking cefuroxime.

Pregnancy Use

Orextil is generally safe to use during pregnancy, however, it should be used with caution and only when absolutely necessary. It is important to consult your doctor before taking cefuroxime during pregnancy.

Lactation Use

Orextil is usually safe to use during lactation, however, it should be used with caution and only when absolutely necessary. It is important to consult your doctor before taking cefuroxime while breastfeeding.

Acute Overdose

An overdose of cefuroxime can cause serious side effects, including convulsions, dizziness, loss of consciousness, and even coma in some cases. It is important to seek medical attention immediately if you think you or someone else has taken an overdose of cefuroxime.

Contraindication

Orextil is not to be used in patients with a known allergy or hypersensitivity to cefuroxime or other cephalosporins, or penicillins. Orextil should also not be used in patients with a history of liver or kidney disease.

Use Direction

Orextil should be taken as directed by your doctor. The dosage and frequency should not be exceeded or decreased without consulting your doctor. Taking cefuroxime with food or antacids can help reduce side effects.

Storage Condition

Orextil should be stored at room temperature, below 30°C (86°F). Keep it in a tightly closed container away from light, heat, and moisture.

Volume of Distribution

The volume of distribution of cefuroxime is about 0.4-0.5 L/Kg.

Half Life

Orextil has a half-life of 2-3 hours.

Clearance

Orextil is cleared from the body by both hepatic and renal pathways. The total clearance is 6.3 mL/min/kg.

Here you find in details version of Orextil

Some Frequently Asked Questions About Orextil

What is Orextil?

Orextil is an antibiotic used to treat a wide variety of infections caused by bacteria. It works by stopping the growth of bacteria. It is available in brand and generic form.

What is Orextil used to treat?

Orextil is indicated to treat bacterial infections, including upper and lower respiratory tract, urinary tract, skin, and soft tissue infections.

Does Orextil have side effects?

Orextil may cause side effects such as nausea, vomiting, diarrhea, headache, or dizziness.

Can Orextil be used to treat bronchitis?

Yes, Orextil is commonly used to treat infections caused by bronchitis.

Is Orextil a penicillin drug?

No, Orextil is not a penicillin drug. It is a cephalosporin antibiotic.

Is Orextil safe to use during pregnancy?

Orextil is generally considered safe to use during pregnancy. However, it is recommended to consult a doctor before using any medication during pregnancy.

What is the recommended dosage of Orextil?

The recommended dosage of Orextil depends on the severity of the infection. It is recommended to consult a doctor for the exact dosage.

Can Orextil be used in children?

Yes, Orextil can be used in children. However, the dosage may need to be adjusted according to the severity of the infection.

Can Orextil be taken with food?

Yes, Orextil can be taken with food. However, it is recommended to take the medication with a full glass of water.

Does Orextil cause weight gain?

No, Orextil does not cause weight gain. However, it is recommended to consult a doctor if any unusual symptom is observed.

Is Orextil an over the counter drug?

No, Orextil is not available as an over the counter drug. It is available with a doctor's prescription.

What is the shelf life of Orextil?

The shelf life of Orextil is two years when stored under proper conditions.

Can Orextil cause a yeast infection?

Yes, Orextil may cause a yeast infection as a side effect.

What are the common side effects of Orextil?

The common side effects of Orextil include nausea, vomiting, dizziness, headache, or diarrhea.

Can Orextil be used to treat a sinus infection?

Yes, Orextil is commonly used to treat a sinus infection.

What are the contraindications of Orextil?

Orextil should not be used in patients with hypersensitivity to cephalosporin, penicillin, or any other medication.

Can Orextil be taken long term?

Yes, Orextil can be taken long term under the supervision of a doctor.

Can Orextil be used to treat a urinary tract infection?

Yes, Orextil is commonly used to treat a urinary tract infection.

Does Orextil cause headache?

Yes, Orextil may cause a headache as a side effect.

Can Orextil be used to treat an ear infection?

Yes, Orextil is commonly used to treat an ear infection.

What should be avoided while taking Orextil?

Alcohol and grapefruit should be avoided while taking Orextil.

What is the generic name of Orextil?

The generic name of Orextil is cefuroxime axetil.

Can Orextil be used to treat pneumonia?

Yes, Orextil can be used to treat pneumonia.

What are the pharmacological actions of Orextil?

Orextil has antibacterial, anti-inflammatory, and immunomodulatory actions.

What is the dose of Orextil for adults?

The dose of Orextil for adults is 250mg-500mg twice daily.

Can Orextil be used to treat an STD?

Yes, Orextil can be used to treat some Sexually Transmitted Diseases.

Does Orextil interact with other medications?

Yes, Orextil may interact with other medications such as aspirin and ibuprofen.

Can Orextil cause diarrhea?

Yes, Orextil may cause diarrhea as a side effect.

How long does it take for Orextil to work?

It can take up to several days for Orextil to start working. However, the exact time depends on the severity of the infection.

Does Orextil cause drowsiness?

Yes, Orextil may cause drowsiness as a side effect.

How is Orextil administered?

Orextil is administered orally in tablet or capsule form.

Can Orextil be used to treat a strep throat?

Yes, Orextil is commonly used to treat a strep throat.

Does Orextil cause stomach upset?

Yes, Orextil may cause stomach upset as a side effect.

Does Orextil treat UTI?

Yes, Orextil is commonly used to treat UTI (Urinary Tract Infection).

What is the dosage of Orextil for children?

The dosage of Orextil for children depends on the age and weight of the child. It is recommended to consult a doctor for the exact dosage.

Is Orextil an antibiotic?

Yes, Orextil is an antibiotic used to treat a wide variety of bacterial infections.

Is Orextil effective against staphylococcus aureus?

Yes, Orextil is effective against staphylococcus aureus.

What is the usual duration of treatment for Orextil?

The usual duration of treatment with Orextil is 5-7 days.

Does Orextil have an expiration date?

Yes, Orextil has an expiration date. It is recommended to check the expiration date before using the medication.

Can Orextil be used to treat a sinus infection?

Yes, Orextil is commonly used to treat a sinus infection.

Is Orextil an over the counter drug?

No, Orextil is not available as an over the counter drug. It is available with a doctor's prescription.