Orbidex G
Orbidex G Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Orbidex G is a brand name. Its generic name is Gatifloxacin + Dexamethasone.
Orbidex G Introduction
Orbidex G is an antibiotic and steroid combination drug used to treat bacterial infections of the upper and lower respiratory tract. It is a combination of the antibiotic gatifloxacin and the corticosteroid dexamethasone that works in combination to fight inflammation in the lungs and airways caused by bacteria.
Uses for Orbidex G
Orbidex G is used to treat bacterial infections of the upper and lower respiratory tract, including bronchitis, sinusitis, and pneumonia. It is also used to reduce inflammation and swelling in the airways of patients with bronchial asthma. In addition, this drug has been used to treat certain types of skin and soft tissue infections.
Mechanism of Action
Gatifloxacin works by inhibiting the growth of bacterial cells, while dexamethasone blocks the production of substances in the body that cause inflammation. Together, their combination helps reduce inflammation and swelling in the airways and improve breathing in patients with bronchial asthma.
How Long Does It Take to Work?
Orbidex G takes about 2-3 days to begin working. Most patients begin to notice an improvement in breathing, coughing, and other respiratory symptoms within 24-48 hours.
Absorption
Orbidex G is quickly absorbed from the gastrointestinal (GI) tract.
Route of Elimination
Orbidex G is eliminated mainly by the kidneys, with a small portion excreted in the bile.
Dosage
Orbidex G is available as a tablet and an oral suspension. The recommended dose for adults is one tablet or 10 ml of oral suspension 3 times a day, with or without food.
Administration
Orbidex G should be taken orally with a glass of water, with or without food. Do not crush or chew the tablets.
Side Effect
Orbidex G may cause some common side effects such as nausea, vomiting, diarrhea, headache, rash, dizziness, and insomnia. More serious side effects may include changes in blood sugar, mild allergic reactions, changes in vision, irregular heartbeat, and difficulty breathing.
Toxicity
Orbidex G has been associated with rare cases of severe ototoxicity, nephrotoxicity, and hepatotoxicity. Seek medical attention immediately if you experience any of these symptoms.
Precaution
Orbidex G should be used with caution in patients with a known or suspected allergy to fluoroquinolones or corticosteroids, or in patients with renal or hepatic impairment.
Interaction
Orbidex G may interact with certain drugs and increase the risk of side effects. Before taking this medication, tell your doctor about all other medications you are taking.
Disease Interaction
Orbidex G may interact with certain diseases and increase the risk of side effects. Tell your doctor about all medical conditions, including a history of liver or kidney disease, diabetes, heart disease, or thyroid problems.
Drug Interaction
Orbidex G may interact with certain drugs and increase the risk of side effects. Tell your doctor about all drugs you are taking, including prescription and non-prescription medications, vitamins, and herbal supplements.
Food Interactions
Orbidex G may interact with certain foods and drinks and increase the risk of side effects. Avoid grapefruit and grapefruit juice while taking this medication.
Pregnancy Use
Orbidex G is not recommended for use in pregnant women. In animal studies, the combination drug has been associated with problems in development and growth, and it has not been studied in pregnant women.
Lactation Use
Orbidex G is not recommended for use in nursing mothers. The drug has the potential to pass into breast milk and can cause harm to a breastfeeding infant.
Acute Overdose
If an overdose is suspected, seek medical attention immediately. Some of the symptoms of an overdose may include confusion, nausea, vomiting, abnormal heart rate, seizures, and coma.
Contraindication
Orbidex G is contraindicated in patients with a history of hypersensitivity to fluoroquinolones, corticosteroids, or other components of the drug.
Use Directions
Orbidex G should be taken as directed by your doctor. Follow all instructions on the product label and package insert and do not take more or less than prescribed.
Storage Condition
Orbidex G should be stored at room temperature, away from light and moisture. Keep this medication out of reach of children and pets.
Volume of Distribution
Orbidex G has a volume of distribution of 0.27 L/kg.
Half Life
The half-life of Orbidex G is approximately 18-24 hours.
Clearance
Orbidex G has a clearance rate of 0.091 L/hr/kg.
Here you find in details version of Orbidex G