Neosetin R

Neosetin R Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Neosetin R is a brand name. Its generic name is Ranitidine.

Introduction

Neosetin R is a histamine-2(H2)-blocker used to treat and prevent stomach and duodenal ulcers, and to treat other stomach and gastrointestinal conditions. It is an over-the-counter drug, available both as a prescription and non-prescription medication.

Uses

Neosetin R is used to treat gastrointestinal disorders such as gastroesophageal reflux disease (GERD), ulcers, and other conditions involving excessive stomach acid. It can also be used to prevent stress ulcers, to treat heartburn, and to reduce the occurrence of stomach or duodenal ulcers

Mechanism of Action

Neosetin R works by reducing the amount of acid produced by the stomach, therefore reducing the symptoms of heartburn and other gastrointestinal conditions. It does this by blocking histamine-2, which reduces the amount of acid production in the stomach in response to food.

How Long Does it Take to Work?

Neosetin R begins to reduce stomach acid production and improve symptoms within a few hours or days after the first dose. The maximum benefit is usually reached within 4 weeks.

Absorption

Neosetin R is well absorbed in the stomach and intestine. It has an oral absorption rate of 65-80%.

Route of Elimination

Neosetin R is eliminated by the kidneys through urine via glomerular filtration and tubular secretion. Its elimination half-life is 1-2 hours.

Dosage

Neosetin R is available in tablets, capsules, and suspension forms. The dosage forms and strengths are as follows:

  • Tablet: 75 mg, 150 mg, and 300 mg
  • Capsules: 75 mg and 150 mg
  • Suspension: 10 mg/mL

The usual adult dose for treatment of active duodenal ulcers is 150 mg to 300 mg twice daily. For maintenance of healing of duodenal ulcers, 150 mg once daily is recommended.

For treatment of esophageal reflux, the usual dose is 150 to 300 mg twice daily. For maintenance of healing of esophageal lesions, the recommended dose is 150 mg once daily.

For treatment of conditions involving excessive stomach acid, the recommended dose is 150 to 300 mg twice daily.

Administration

Neosetin R can be taken with or without food. It should be taken with a full glass of water to ensure that it is completely absorbed. It is important to consume the full amount of water that is recommended for each dose.

Side Effects

Common side effects of ranitidine include headache, diarrhea, constipation, nausea, rash, dizziness, and abdominal pain. Less common side effects may include muscle pain, joint pain, fever, mental confusion, and depression.

Toxicity

Neosetin R has a low toxicity and is generally well tolerated. Large doses may cause hypotension and can be fatal in cases of overdose.

Precautions

Neosetin R should be used with caution in people with kidney or liver disease, and those with a history of drug allergies.

Interactions

Neosetin R may interact with other medications including antacids, drugs used to treat heartburn, anti-seizure medications, certain antibiotics, and theophyllines.

Disease Interactions

Neosetin R should not be used in people with porphyria, a rare metabolic disorder. It should also be used with caution in people with severe kidney disease.

Drug Interactions

Neosetin R can interact with certain medications such as antacids, drugs used to treat heartburn, anti-seizure medications, certain antibiotics, and theophyllines. Be sure to discuss all medications you are taking with your healthcare provider before taking ranitidine.

Food Interactions

Neosetin R may interact with food. Consuming alcohol while taking ranitidine may increase the risk of side effects such as headache, dizziness, and drowsiness.

Pregnancy Use

Neosetin R should only be used during pregnancy if the potential benefit justifies the potential risk to the fetus. Be sure to discuss the use of ranitidine with your healthcare provider before using it during pregnancy.

Lactation Use

Neosetin R is excreted in breast milk and may affect a nursing baby. Therefore, it should be used with caution in breastfeeding women.

Acute Overdose

If an overdose of Neosetin R occurs, seek medical attention immediately. Symptoms of overdose may include low blood pressure, dizziness, and unusual sleepiness.

Contraindication

Neosetin R is contraindicated in people who are allergic to the active ingredient in the drug.

Use Direction

Neosetin R should be taken as directed by your healthcare provider. The usual adult dose for treatment of active duodenal ulcers is 150 mg to 300 mg twice daily. For maintenance of healing of duodenal ulcers, 150 mg once daily is recommended.

Storage Condition

Neosetin R should be stored at room temperature, away from heat and moisture. Keep out of reach of children.

Volume of Distribution

The apparent volume of distribution for Neosetin R is 5L/kg.

Half Life

The half-life of Neosetin R is 1-2 hours.

Clearance

The clearance for Neosetin R is 10 mL/min/kg.

Here you find in details version of Neosetin R

Some Frequently Asked Questions About Neosetin R

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What is Neosetin R?

Neosetin R is an over-the-counter and prescription histamine-2 blocker or H2 blocker used to treat gastroesophageal reflux disease (GERD), Zollinger-Ellison Syndrome (ZES) and other conditions caused by too much acid in the stomach.

How does Neosetin R work?

Neosetin R works by inhibiting the production of acid in the stomach, thus reducing the symptoms of acid reflux. It can also protect the lining of the stomach from damage due to the excess stomach acid.

What is the brand name of Neosetin R?

The brand name of Neosetin R is Zantac.

What is the dosage of Neosetin R?

The dosage of Neosetin R depends on the medical condition and age of the patient; however, the usual dosage for adults in the treatment of acid reflux is 150 mg twice a day.

What are the side effects of Neosetin R?

The most common side effects of Neosetin R include headache, dizziness, nausea, and diarrhea. Other less common side effects include constipation, stomach pain, and rash.

Does Neosetin R interact with other medications?

Yes, Neosetin R can interact with other medications such as anticoagulants, sulfonylureas, and NSAIDs. Talk to your doctor or pharmacist before taking any other medication while taking Neosetin R.

What is the difference between Neosetin R and Famotidine?

Neosetin R and Famotidine are both H2 blockers used for treating acid reflux and GERD. The main difference between them is that Neosetin R is more effective for treating Zollinger-Ellison Syndrome. In terms of side effects, Neosetin R may cause headaches and dizziness, while Famotidine may cause diarrhea.

Can I take Neosetin R while pregnant/breastfeeding?

It is not recommended to take Neosetin R while pregnant or breastfeeding as it may be harmful to the fetus or infant. Talk to your doctor before taking Neosetin R during pregnancy or while breastfeeding.

How long does it take for Neosetin R to work?

Neosetin R usually begins to work within an hour of taking it and continues to work for up to 12 hours.

Can I take Tylenol (acetaminophen) and Neosetin R together?

Yes, it is safe to take Tylenol (acetaminophen) and Neosetin R together.

Is Neosetin R a laxative?

No, Neosetin R is not a laxative.

How should I take Neosetin R?

Neosetin R should be taken with or without food as prescribed by a doctor. It is important to take Neosetin R exactly as prescribed and not to take more or less than recommended.

Can I take Neosetin R long-term?

Neosetin R can be taken long-term if it is necessary and advised by your doctor. It may be necessary to take Neosetin R long-term to treat certain conditions, such as Zollinger-Ellison Syndrome.

What foods should I avoid while taking Neosetin R?

It is recommended to avoid eating any food that increases the production of acid in the stomach, such as alcohol, caffeine, spicy foods, and citrus fruits while taking Neosetin R.

Can Neosetin R cause weight gain?

No, there is no evidence to suggest that Neosetin R is linked to weight gain.

Can I take Omeprazole and Neosetin R together?

No, it is not recommended to take Omeprazole and Neosetin R together as they are both H2 blockers that work by suppressing acid production in the stomach.

Can I take vitamin C while taking Neosetin R?

Yes, it is safe to take vitamin C while taking Neosetin R.

Does Neosetin R raise blood pressure?

No, there is no evidence to suggest that Neosetin R is linked to increased blood pressure.

Can I take Neosetin R if I have diabetes?

Yes, it is safe to take Neosetin R if you have diabetes.

Can I take ibuprofen and Neosetin R together?

Yes, it is safe to take ibuprofen and Neosetin R together.

Can I take aspirin and Neosetin R together?

Yes, it is safe to take aspirin and Neosetin R together.

Does Neosetin R cause constipation?

Yes, Neosetin R can cause constipation in some people. If you experience constipation while taking Neosetin R, it is important to contact your doctor.

Can I take Pepto-Bismol and Neosetin R together?

No, it is not recommended to take Pepto-Bismol and Neosetin R together as they both contain bismuth, which can have adverse effects when taken together.

What is the best time of day to take Neosetin R?

The best time of day to take Neosetin R depends on the dosage prescribed by your doctor. However, as a general rule, it is best to take the medication after meals or before bedtime.

Can I take Axid and Neosetin R together?

No, it is not recommended to take Axid and Neosetin R together as they both contain similar active ingredients and can lead to an overdose.

Can Neosetin R cause liver damage?

Neosetin R is not known to cause liver damage; however, if you notice any signs or symptoms of liver damage, it is important to contact your doctor immediately.

Can I take synthroid and Neosetin R together?

Yes, it is safe to take synthroid and Neosetin R together.

Does Neosetin R cause weight loss?

No, there is no evidence to suggest that Neosetin R is linked to weight loss.

Can Neosetin R increase anxiety?

Yes, Neosetin R can increase anxiety in some people. If you experience anxiety while taking Neosetin R, it is important to contact your doctor.

Can Neosetin R cause diarrhea?

Yes, Neosetin R can cause diarrhea in some people. If you experience diarrhea while taking Neosetin R, it is important to contact your doctor.

Can I take Prilosec and Neosetin R together?

No, it is not recommended to take Prilosec and Neosetin R together as they both contain similar active ingredients and can lead to an overdose.

Can I take phentermine and Neosetin R together?

Yes, it is safe to take phentermine and Neosetin R together.

Can I take smellaid and Neosetin R together?

Yes, it is safe to take smellaid and Neosetin R together.

Can I take Zofran and Neosetin R together?

Yes, it is safe to take Zofran and Neosetin R together.

Can I take Allegra and Neosetin R together?

Yes, it is safe to take Allegra and Neosetin R together.

Can I take a multivitamin and Neosetin R together?

Yes, it is safe to take a multivitamin and Neosetin R together.

Can I take Tagamet and Neosetin R together?

No, it is not recommended to take Tagamet and Neosetin R together as they both contain similar active ingredients and can lead to an overdose.

Can Neosetin R cause stomach pain?

Yes, Neosetin R can cause stomach pain in some people. If you experience stomach pain while taking Neosetin R, it is important to contact your doctor.

Can I take ibuprofen and Neosetin R at the same time?

Yes, it is safe to take ibuprofen and Neosetin R at the same time.

Can I take aspirin and Neosetin R at the same time?

Yes, it is safe to take aspirin and Neosetin R at the same time.

Can Neosetin R cause headaches?

Yes, Neosetin R can cause headaches in some people. If you experience headaches while taking Neosetin R, it is important to contact your doctor.

Can I take Benadryl and Neosetin R together?

Yes, it is safe to take Benadryl and Neosetin R together.

Can I take Tylenol and Neosetin R together?

Yes, it is safe to take Tylenol and Neosetin R together.

Can I take Prevacid and Neosetin R together?

No, it is not recommended to take Prevacid and Neosetin R together as they both contain similar active ingredients and can lead to an overdose.

Can I take Neosetin R and Pepcid AC together?

No, it is not recommended to take Neosetin R and Pepcid AC together as they both contain similar active ingredients and can lead to an overdose.

Can Neosetin R cause dizziness?

Yes, Neosetin R can cause dizziness in some people. If you experience dizziness while taking Neosetin R, it is important to contact your doctor.