Nebaskin Plus
Nebaskin Plus Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Nebaskin Plus is a brand name. Its generic name is Neomycin Sulfate + Bacitracin Zinc + Polymyxin B.
Introduction
Neomycin sulfate, bacitracin zinc, and polymyxin B sulfate are combination medications used to treat a variety of skin and eye infections. These drugs are antimicrobials that work by preventing the growth of bacteria.Uses
Neomycin sulfate, bacitracin zinc, and polymyxin B sulfate combination drugs are used to treat a variety of skin and eye infections, including bacterial infections of the eyes and external ear, infections of the eye tissue itself, and superficial skin infections.Mechanism of Action
Neomycin sulfate inhibits protein synthesis in sensitive bacteria which, in turn, leads to the death of the bacteria. Bacitracin zinc prevents bacteria from making certain cell wall precursors. Polymyxin B helps to kill bacteria by disrupting the cells outer membrane and causing the cell contents to leak.How Long Does it Take to Work?
It usually takes between 1-3 days for Neomycin sulfate, bacitracin zinc, and polymyxin B sulfate to start working, and the full effect should be seen after 5-7 days of use.Absorption
Neomycin sulfate, bacitracin zinc, and polymyxin B sulfate combination drugs are not normally absorbed into the bloodstream.Route of Elimination
Due to the lack of absorption, these drugs are eliminated through the feces and urine.Dosage
The recommended dosage of Neomycin sulfate, bacitracin zinc, and polymyxin B sulfate is one drop or ointment in the affected eye four times daily. For skin infections, the usual dose is 1-2 drops four times daily for up to one week.Administration
The medication should be administered in the affected eye(s) or area of skin using a clean dropper or applicator.Side Effects
The most common side effects of Neomycin sulfate, bacitracin zinc, and polymyxin B sulfate are burning, stinging, redness, and itching in the area of application. Other side effects may include swelling, blistering, and peeling of the skin.Toxicity
Neomycin sulfate, bacitracin zinc, and polymyxin B sulfate are generally safe and well tolerated, but they can cause serious side effects such as rashes, hives, or difficulty breathing in rare cases.Precautions
Patients should not use Neomycin sulfate, bacitracin zinc, and polymyxin B sulfate in the eyes or on broken skin, and should not apply the medication to large areas of the body. Patients should also avoid contact lenses while using this medication.Interaction
Neomycin sulfate, bacitracin zinc, and polymyxin B sulfate may interact with other medications that are applied to the skin or taken by mouth. It is important to tell your doctor or pharmacist about all the medications you are taking before using this combination medication.Disease Interaction
There are no known disease interactions with Neomycin sulfate, bacitracin zinc, and polymyxin B sulfate.Drug Interactions
Neomycin sulfate, bacitracin zinc, and polymyxin B sulfate may interact with certain medications or other chemicals, including certain antacids, certain antibiotics, and other topical medications. It is important to tell your doctor or pharmacist about all the medications you are taking before using this combination medication.Food Interactions
Neomycin sulfate, bacitracin zinc, and polymyxin B sulfate are not known to interact with food.Pregnancy Use
Neomycin sulfate, bacitracin zinc, and polymyxin B sulfate should be used with caution during pregnancy since it is not known if it could cause harm to the fetus.Lactation Use
Neomycin sulfate, bacitracin zinc, and polymyxin B sulfate are classified as pregnancy category C and should not be used by pregnant or nursing women.Acute Overdose
There have been no reports of an acute overdose of Neomycin sulfate, bacitracin zinc, and polymyxin B sulfate. If an overdose is suspected, seek medical attention immediately.Contraindication
Neomycin sulfate, bacitracin zinc, and polymyxin B sulfate should not be used by patients with known hypersensitivity to any of the components.Use Directions
It is important to follow the directions on the product carefully when using Neomycin sulfate, bacitracin zinc, and polymyxin B sulfate. It should be applied to the affected area four times daily, or as directed by your doctor or pharmacist.Storage Condition
Neomycin sulfate, bacitracin zinc, and polymyxin B sulfate should be stored at room temperature, between 15-30°C (59-86°F).Volume of Distribution
Neomycin sulfate, bacitracin zinc, and polymyxin B sulfate combination drugs are not absorbed into the bloodstream so there is no distribution to other tissues in the body.Half Life
Neomycin sulfate, bacitracin zinc, and polymyxin B sulfate combination drugs have a short elimination half-life, so their effects are temporary.Clearance
Due to the lack of absorption, Neomycin sulfate, bacitracin zinc, and polymyxin B sulfate are eliminated through the feces and urine.Here you find in details version of Nebaskin Plus