Nafgal
Nafgal Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Nafgal is a brand name. Its generic name is Naftifine.
Nafgal
Nafgal is a synthetic antifungal drug that belongs to a class of nitrogen-containing antifungals called allylamines. It is used to treat various types of skin infections caused by fungus, such as athlete's foot, jock itch, ringworm, and other types of tinea infections. Nafgal is available in both topical and oral forms.
Uses
Nafgal is used to treat various infections of the skin caused by fungi such as athlete's foot, jock itch, ringworm, and other types of tinea infections. It is also used to treat certain types of fungal-related diaper rash.
Mechanism of Action
Nafgal works by inhibiting the growth of the causative organisms, including certain fungi like Candida, Trichophyton, Epidermophyton, and Microsporum. By preventing the growth of the fungus, it stops the fungal infection from spreading and helps reduce the symptoms associated with it such as itching, burning, and pain.
How Long Does It Take To Work?
The effects of naftifine can begin to be felt within 24-48 hours of its application. In order to see optimal results, it is important to use naftifine as directed and continue its use until the infection has cleared up.
Absorption
Nafgal is quickly absorbed into the skin with its effectiveness being enhanced when it is applied 2-3 times daily. It is applied directly to the affected area, and can be in cream, gel, and ointment form.
Route of Elimination
Nafgal is primarily eliminated via the kidneys. The amount that is eliminated depends on the dose and the frequency of application.
Dosage
The recommended dosage of naftifine is two to three times daily, depending on the type and severity of the infection. It is most commonly administered as a topical cream, lotion, or ointment applied to the affected area. When used orally, the dosage is 1-2g/day.
Administration
Nafgal can be taken orally or applied topically as a cream, ointment, or lotion. When using it topically, apply to the affected area two to three times a day. When taking naftifine orally, take it with a full glass of water and follow your doctor’s instructions carefully.
Side Effects
Common side effects of naftifine use include itching, stinging, burning, dryness, redness, flaking, and peeling of the skin. Less common side effects include nausea, vomiting, headache, dizziness, blurred vision, and abdominal pain. Contact your doctor if these side effects persist. It is important to note that long-term use of naftifine can be associated with liver toxicity.
Toxicity
Prolonged use of naftifine has been associated with liver toxicity including an increased risk of liver failure. If nausea, vomiting, stomach pain, fatigue, jaundice, dark urine or any other unusual side effects are experienced after taking naftifine, contact your doctor immediately. Also notify your doctor if you are pregnant or plan to become pregnant during the course of treatment since there may be an increased risk of adverse effects.
Precaution
Nafgal should be avoided if you are allergic to it or any of its ingredients. Do not use naftifine in children. Women who are pregnant, planning to become pregnant, or breastfeeding should avoid naftifine and consult a doctor before using it. Do not use naftifine if you have any existing liver problems as it may cause liver toxicity.
Interaction
Nafgal may interact with certain medications like corticosteroids, oral antifungals, and anticoagulants. It is important to always inform your doctor about any medications you are taking before taking naftifine.
Disease Interaction
Nafgal has been known to interact with renal and hepatic disease. People with a kidney disorder or reduced kidney function may need a lower dose of naftifine while people with a weakened liver may not be able to use this medicine as it may affect their liver function. People with any underlying liver problems should consult a doctor before using naftifine.
Drug Interaction
Nafgal may interact with certain medications like corticosteroids, oral antifungals, and anticoagulants. Therefore, it is important to inform your healthcare provider about any drugs you are taking before taking naftifine.
Food Interactions
Nafgal may interact with certain foods or dietary supplements, particularly those containing nystatin or antifungal drugs. Therefore, it is important to inform your healthcare provider about any foods you are consuming before taking naftifine.
Pregnancy Use
Nafgal is a pregnancy category C drug, meaning that its safety in pregnant women has not been established. Therefore, women who are pregnant or plan to become pregnant should consult a doctor before taking naftifine.
Lactation Use
Nafgal is not known to be safe for use in breastfeeding women, and therefore its use in breastfeeding women is not recommended.
Acute Overdose
If an overdose of naftifine is suspected, call for medical assistance immediately as medical attention is necessary. Symptoms of an acute overdose may include itching, redness, burning, and dryness of the skin, nausea, vomiting, abdominal pain, headache, blurred vision, dizziness, and liver toxicity.
Contraindication
Nafgal is contraindicated in individuals who have had hypersensitivity reactions to it or any of its ingredients. It is not recommended for use in children. Women who are pregnant, planning to become pregnant, or breastfeeding should avoid taking naftifine and consult a doctor before using it.
Use Directions
Nafgal should be applied directly to the affected area as directed by the doctor or pharmacist. It can be taken orally or applied topically as a cream, ointment, or lotion. When taking naftifine orally, take it with a full glass of water. When using naftifine topically, apply it twice to three times daily or as directed by your doctor. Continue to use naftifine until the infection clears up. If no improvement is seen after two to four weeks, contact your doctor.
Storage Conditions
Store naftifine in a dry, dark place, away from direct sunlight and heat. Keep naftifine in the original container until use, keep out of reach of children, and discard any unused naftifine.
Volume of Distribution
The volume of distribution of naftifine is not known.
Half Life
The half-life of naftifine is approximately 4 hours in humans.
Clearance
The clearance of naftifine is not known.
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