Mycophenolate mofetil Tillomed

Mycophenolate mofetil Tillomed, a brand name for a formulation containing essential Mycophenolate Mofetil, is widely used for various health benefits. This guide provides comprehensive information on the uses, dosage, side effects, and mechanism of action of Mycophenolate mofetil Tillomed, as well as insights into how long it takes to work. Understanding these aspects can help you make informed decisions about its use and effectiveness.


Mycophenolate mofetil Tillomed (MMF) is a medication used to treat certain immune-mediated conditions such as systemic lupus erythematosus or inflammatory bowel disease. It is also used to help prevent the rejection of organ transplant. It is an ester prodrug of mycophenolic acid, which works by suppressing or reducing the body's immune system.


Mycophenolate mofetil is used to prevent rejection of organ transplants, such as kidney, heart, and liver, as well as to treat inflammatory bowel disease and lupus erythematosus.

Mechanism of Action

Mycophenolate mofetil Tillomed works by blocking certain steps in the production of certain cells in the immune system. It prevents the activation and proliferation of certain lymphocytes that contribute to an immune response, leading to decreased inflammation in the body. It has also been found to reduce the rates of organ rejection in organ transplant patients.

How long does it take to work?

The effects of mycophenolate mofetil can be quite variable, depending upon the underlying condition and the patient. In general, the medication may take anywhere from several days to several weeks to achieve its full effect.


Mycophenolate mofetil is rapidly and almost completely absorbed from the gastrointestinal tract with an absolute bioavailability of 80-90%. Peak serum concentrations are generally reached within 2-4 hours after administration.

Route of Elimination

Mycophenolate mofetil Tillomed is mainly metabolised and eliminated through the kidneys in the form of mycophenolic acid.


The recommended dose of Mycophenolate mofetil Tillomed is based on weight and medical condition. Generally, it should be taken 2-3 times a day either in the form of a tablet or capsule (1g or 500mg). It should be taken with food and should not be chew, split, or crushed.


Mycophenolate mofetil is generally taken orally with a meal or snack. It can also be taken in combination with other immunosuppressants, usually in the form of tacrolimus or cyclosporine.

Side Effects

Common side effects of mycophenolate mofetil include: nausea, vomiting, diarrhea, abdominal pain, hair loss, fatigue, and headache. Other less common side effects include: dizziness, rashes or itching, depression, difficulty breathing, fever, and chest pain.


The most common toxicities associated with mycophenolate mofetil are gastrointestinal disturbances. Mycophenolate mofetil is not known to have any serious long-term toxicities, however it is only recommended to be taken under the close supervision of a medical professional.


Mycophenolate mofetil should not be taken if you are pregnant, planning to become pregnant, breastfeeding, or are allergic to any of the ingredients in the medication. It is also important to tell your doctor if you have any liver, kidney or heart disease.


Mycophenolate mofetil is known to interact with many other medications, including certain antibiotics, antifungals, cholesterol-lowering medications, barbiturates, and hormones. Taking any of these medications could affect the efficacy of Mycophenolate mofetil Tillomed or increase the risk of side effects.

Disease Interaction

Mycophenolate mofetil can reduce the effectiveness of certain vaccines, such as the measles, mumps, and rubella (MMR) vaccine. It can also worsen conditions such as lupus, diabetes, and certain types of cancer such as lymphoma.

Drug Interaction

Mycophenolate mofetil can interact with many other medications. This includes certain antibiotics, antifungals, cholesterol-lowering medications, hormones, and barbiturates. Be sure to tell your doctor if you take any of these medications before taking mycophenolate mofetil.

Food Interaction

Mycophenolate mofetil is best taken with food, as grape fruit juice or certain foods with high concentrations of calcium, iron, dietary fiber, and vitamin D can possibly reduce the medication's absorption. Additionally, it is recommended to avoid alcohol while taking Mycophenolate mofetil Tillomed due to increased risk of side effects.

Pregnancy Use

Mycophenolate mofetil is generally not recommended for pregnant women due to possible serious side effects.

Lactation Use

Mycophenolate mofetil is not recommended for breastfeeding mothers due to the potential risk of passing the drug to their infants.

Acute Overdose

High doses of Mycophenolate mofetil can lead to an increased risk of serious side effects. In case of an overdose, seek medical attention immediately and inform your doctor or pharmacist of the last dose taken.


Mycophenolate mofetil is contraindicated in pregnant women as well as those with a known allergy to the medication. It is also contraindicated in patients with certain active infections or conditions that suppress the immune system.

Use Direction

Take Mycophenolate mofetil exactly as prescribed by your doctor. Do not take more or less of it or take it for longer than recommended. Take it with food and follow all instructions on the prescription label.

Storage Condition

Mycophenolate mofetil should be stored at room temperature between 59°F and 77°F (15°C and 25°C). It should be kept out of reach of children, and away from light and heat.

Volume of Distribution

Mycophenolate mofetil has relatively large volume of distribution (9L-20L).

Half Life

The half-life of Mycophenolate is 2-3 hours.


Mycophenolate mofetil is cleared primarily by the kidneys, with a reported renal clearance of 37-144 mL/min.

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