Monivis
Monivis Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Monivis is a brand name. Its generic name is Tiemonium Methylsulphate.
Introduction
Monivis (TM), also known as Ragwitek or Merck Brand name Tezepelumab, is a biological drug used to treat moderate to severe atopic dermatitis. It belongs to a class of medications known as monoclonal antibodies. It works by blocking chemicals that are involved in inflammation.Uses
Monivis is typically used to treat moderate to severe atopic dermatitis (eczema) in both adults and children aged 6 years and older. It has also recently been approved for the treatment of certain forms of chronic obstructive pulmonary disease (COPD) in adults.Mechanism of Action
Monivis works by blocking a protein called thymic stromal lymphopoietin (TSLP), which is involved in the inflammation associated with atopic dermatitis. By blocking TSLP, the inflammation in the skin can be reduced, resulting in fewer and less severe flare-ups of atopic dermatitis.How Long Does it Take to Work?
The effects of Monivis can be seen as soon as 1 week after starting treatment, although it may take up to 8 weeks to see full results.Absorption
Monivis is administered as an injection under the skin (subcutaneously). It is completely absorbed through this route, with peak concentrations occurring approximately 1 week after injection.Route of Elimination
Monivis is eliminated through the kidneys, primarily as its active metabolite, desethyl tiemonium, which is excreted in urine.Dosage
The recommended dosage of Monivis is 200 mg given as an injection beneath the skin (subcutaneously) every 4 weeks.Administration
Monivis should be administered as an injection beneath the skin (subcutaneously) into the abdominal area, thigh, or upper arm. Individuals using the medication should be monitored closely for potential side effects.Side Effects
Common side effects of Monivis may include:- Redness, pain, or swelling at the injection site
- Headache
- Joint pain
- Nausea
- Diarrhea
- Fever
- Fatigue
Toxicity
There are no reports of toxicity associated with Monivis use, however it can cause serious side effects in certain individuals.Precautions
- Monivis should not be used by individuals with known hypersensitivity to the drug or any of its components.
- Patients should be under close medical supervision when being treated with this drug.
- Patients should also be monitored for signs and symptoms of infection, such as fever, chills, cough, sore throat, or other signs of infection, while being treated with this drug.
Interactions
Monivis may interact with other medications, herbs, or supplements that may also affect the skin, including retinoids, calcitriol, and tacrolimus.Disease Interactions
Monivis should be used with caution in patients with severe kidney disease, cirrhosis of the liver, or HIV/AIDS.Drug Interactions
Monivis may interact with certain drugs, including antiepileptic drugs, immunosuppressants, and other drugs that are used to treat atopic dermatitis. Patients should consult with their healthcare provider before taking Monivis alongside any other medications.Food Interactions
Food interactions with Monivis are not known.Pregnancy Use
Monivis should not be used during pregnancy unless absolutely necessary. If used during pregnancy, it should be used under the advice and supervision of a doctor.Lactation Use
It is not known if Monivis is excreted in breastmilk. Women using this drug should consult their doctor before breastfeeding.Acute Overdose
The effects of an acute overdose are not known. Seek medical attention immediately if an overdose is suspected.Contraindication
Monivis is contraindicated in individuals with a known hypersensitivity to the drug or any of its components. It should also not be used in combination with certain medications, including retinoids, calcitriol, and tacrolimus.Use Direction
Monivis is administered as an injection beneath the skin (subcutaneously) into the abdominal area, thigh, or upper arm. The recommended dose is 200 mg every 4 weeks.Storage Conditions
Monivis should be stored at 2°C to 8°C (36°F to 46°F).Volume of Distribution
The volume of distribution of Monivis is not known.Half-Life
The half-life of Monivis is approximately 22 days.Clearance
The clearance of Monivis is not known.Here you find in details version of Monivis
Some Frequently Asked Questions About Monivis
you can give answe only.What is Monivis?
Monivis is an savoury aviatory stimulant used to trear cardiac arrhythmia and preductal tachycardia. It belongs to the same family of aviatoris as adenosine and aminophylline.
What is the chemical name of Monivis?
The chemical name of Monivis is (2RS, 3aRS, 7RS, 7aR)-2-[(ethanesulphonyl)amino]-3-phenyl-7-methyl-7-azabicyclo[3.3.1]nonan-3-ium sulphate.
How is Monivis taken?
Monivis is usually taken intravenously as a drip. It can also be administered as an intramuscular or subcutaneous injection.
What are the side Effects of Monivis?
The most common side effects of Monivis include dizziness, nausea, and sweating. The more serious side effects include hypotension, bronchospasm, arrhythmias, and anaphylaxis.
How long does Tiemonium methylsulphate last?
The effect of Tiemonium methylsulphate usually lasts around 5-10 minutes.
What is the dosage of Monivis?
The recommended dose of Monivis is 10 mg intravenously, followed by an infusion of 1 mg/minute.
When should Monivis be used?
Monivis should be used in patients with refractory cardiac arrhythmia, including supraventricular tachycardia, ventricular tachycardia, and atrial fibrillation.
Who should not take Monivis?
Monivis should not be taken by people who have an allergy to it, people with asthma, or people who have a history of Raynaud's disease.
What happens if I overdose on Monivis?
An overdose of Monivis can result in serious side effects, including hypotension, arrhythmias, and bronchospasm. An overdose of Monivis is a medical emergency and should be treated as such.
What are the interactions of Monivis with other medications?
Monivis may interact with certain medications, including beta-blockers, non-dihydropyridine calcium channel blockers, and theophylline. Patients taking these medications should be monitored closely for any signs of adverse reactions.
What is the shelf life of Monivis?
The shelf life of Monivis is three years from the date of manufacture.
Is Monivis used for pregnant women?
The safety of Monivis for pregnant women has not been established. Women who are pregnant or planning to become pregnant should consult their healthcare provider before taking Monivis.
Is there any generic version of Monivis available?
No, there is not a generic version of Monivis available.
How long does it take for Monivis to take effect?
The effect of Monivis is usually immediate.
How often can Monivis be taken?
Monivis should not be taken more than once every six hours.
What are some alternatives to Monivis?
Alternatives to Monivis include adenosine, aminophylline, and calcium channel blockers.
Can Monivis be taken with other medications?
Yes, it is possible to take Monivis with other medications, but patients should always consult their healthcare provider before taking any medication in combination with Monivis.
Can I take Monivis if I am breastfeeding?
No, Monivis is not recommended for women who are breastfeeding.
Is Monivis safe for children?
No, Monivis should not be given to children.
Can Monivis be used for pulmonary disorders?
No, Monivis is not recommended for the treatment of pulmonary disorders.
Does Monivis interfere with other medications?
Yes, Monivis can interact with certain medications, including beta-blockers, non-dihydropyridine calcium channel blockers, and theophylline. Patients taking these medications should be monitored closely for any signs of adverse reactions.
Can Monivis be administered orally?
No, Monivis should not be taken orally. It should be given intravenously, intramuscularly, or subcutaneously.
How often should I take Monivis?
Monivis should not be taken more than once every six hours.
What should I do if I miss a dose of Monivis?
If you miss a dose of Monivis, it is important to take it as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule.
What are the symptoms of an allergic reaction to Monivis?
Common symptoms of an allergic reaction to Monivis include rash, hives, itching, difficulty breathing, and swelling of the face, lips, tongue, or throat.
Can I take Monivis with food?
Yes, it is okay to take Monivis with food.
Can I take Monivis if I’m on dialysis?
Monivis should be used with caution in patients on dialysis, as it can interact with certain medications.
What is the cost of Monivis?
The cost of Monivis will vary depending on the dosage and the pharmacy where it is purchased.
Is Monivis habit-forming?
No, Monivis is not known to be habit-forming.
Can Monivis be used to treat arrhythmias?
Yes, Monivis is used to treat certain types of arrhythmias, including ventricular tachycardia and atrial fibrillation.
What are the common side effects of Monivis?
The most common side effects of Monivis include dizziness, nausea, and sweating.
Does Monivis interact with other medications?
Yes, Monivis can interact with certain medications, including beta-blockers, non-dihydropyridine calcium channel blockers, and theophylline. Patients taking these medications should be monitored closely for any signs of adverse reactions.
Is Monivis a controlled substance?
No, Monivis is not a controlled substance.
Should I take Monivis with food?
Yes, it is okay to take Monivis with food.
Can I take Monivis if I’m pregnant?
No, the safety of Monivis for pregnant women has not been established. Women who are pregnant or planning to become pregnant should consult their healthcare provider before taking Monivis.
Can Monivis be given intramuscularly?
Yes, Monivis can be administered intramuscularly.
How should Monivis be stored?
Monivis should be stored at room temperature, protected from light and moisture.
What is the recommended dosage of Monivis?
The recommended dose of Monivis is 10 mg intravenously, followed by an infusion of 1 mg/minute.
Does Monivis cause drowsiness?
Yes, Monivis can cause drowsiness.
Can I take Monivis if I’m taking other medications?
Yes, it is possible to take Monivis with other medications, but patients should always consult their healthcare provider before taking any medication in combination with Monivis.
Is Monivis safe for the elderly?
Yes, Monivis is generally safe for the elderly, however, they should be monitored closely for any signs of adverse reactions.
Can Monivis be used to treat atrial fibrillation?
Yes, Monivis can be used to treat atrial fibrillation.
Can Monivis be used to treat ventricular tachycardia?
Yes, Monivis can be used to treat ventricular tachycardia.