Menakion MM

Menakion MM Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Menakion MM is a brand name. Its generic name is Phylloquinone.

Menakion MM: Introduction

Menakion MM (also known as vitamin K) is a fat-soluble vitamin essential for normal blood clotting and the protection of the cardiovascular system. Menakion MM is found in green leafy vegetables, vegetable oils, dairy products, and liver. Menakion MM is also known as phylloquinone-4 (or K1).

Uses for Menakion MM

Menakion MM is a key component in the regulation of blood clotting. It helps to produce a protein called prothrombin, which is essential for the formation of blood clots. In addition, Menakion MM also helps to prevent hardening of the arteries (atherosclerosis). It may also help to prevent heart disease, osteoporosis, and cancer.

Mechanism of Action

Menakion MM acts as a coenzyme in the gamma-glutamyl carboxylation of certain clotting factors (factors II, VII, IX, and X) needed for blood clotting. Menakion MM also helps to convert Vitamin K-dependent proteins into active forms, allowing them to interact with calcium.

How Long Does It Take to Work

Menakion MM begins working within 1 to 2 days of taking it.

Absorption

Menakion MM is absorbed from the intestine in the presence of dietary fat. It is stored mainly in the liver.

Route of Elimination

Menakion MM is excreted in the bile.

Dosage

The recommended daily intake of Menakion MM for adults is 120 micrograms (mcg) per day. Postmenopausal women are advised to get more Menakion MM (150 mcg per day). Pregnant women should get 90 mcg per day.

Administration

Menakion MM is available in dietary supplements and as an injection. It should be taken orally with food.

Side Effect

Menakion MM is generally well-tolerated. In rare cases, it may cause skin rash, nausea, and headache.

Toxicity

Menakion MM is not toxic in recommended doses.

Precaution

Patients taking anticoagulants (e.g. warfarin) should use Menakion MM with caution as it may interfere with the action of the drug.

Interaction

Menakion MM may interact with other medications, such as anticoagulants, corticosteroids, oral contraceptives, and certain antibiotics.

Disease Interaction

Patients with liver or kidney diseases should use Menakion MM with caution as it may be toxic in these conditions.

Drug Interaction

Menakion MM may interact with acetaminophen, aspirin, clopidogrel, ibuprofen, cefepime, penicillin G, metronidazole, and other drugs.

Food Interactions

Menakion MM may interact with foods containing Vitamin E, garlic, green tea, and soy.

Pregnancy Use

Menakion MM is considered to be generally safe for use in pregnancy. However, pregnant women should consult their doctor before taking Menakion MM.

Lactation Use

Menakion MM is deemed safe for use during lactation. However, nursing mothers should consult their doctor before taking Menakion MM.

Acute Overdose

Symptoms of an acute overdose may include diarrhea, palpitations, dizziness, headache, and nausea.

Contraindication

Menakion MM should not be taken by patients who are known to be allergic to it.

Use Direction

Menakion MM should be taken orally with food. It should not be taken on an empty stomach.

Storage Condition

Menakion MM should be stored in a cool, dry place at room temperature (15-30C).

Volume of Distribution

The volume of distribution of Menakion MM is 0.14 l/kg.

Half Life

The half-life of Menakion MM is estimated to be 1.4 days.

Clearance

The clearance of Menakion MM is 24 l/hr/kg.

Here you find in details version of Menakion MM

Some Frequently Asked Questions About Menakion MM

What is Menakion MM?

Menakion MM (also known as vitamin K1) is a vitamin found naturally in plants and used in dietary supplements as well as in the production of some pharmaceuticals and cosmetics. It is involved in important processes such as blood clotting, calcium absorption, and cell growth and differentiation.

What are the benefits of Menakion MM?

Menakion MM is most well-known for its role in regulating blood clotting. It also plays an important role in bone health, as it helps the body absorb and utilize calcium. Additionally, it is an antioxidant and may help protect against age-associated diseases.

What foods contain Menakion MM?

Dark green leafy vegetables such as kale, spinach, and Swiss chard are some of the best sources of phylloquinone. Other foods that are rich in phylloquinone include broccoli, cabbage, cauliflower, Brussels sprouts, and collard greens.

How much Menakion MM should I take?

The recommended daily intake for phylloquinone for adults over the age of 19 is 90-120 µg/day for men and 75-90 µg/day for women. It is important to talk to your doctor before taking any dietary supplement or medication to make sure the dosages are safe and appropriate.

Is Menakion MM the same as Vitamin K?

Yes, Menakion MM (vitamin K1) is the same as Vitamin K. Vitamin K can be divided into two categories, Vitamin K1 (phylloquinone) and Vitamin K2 (menaquinone), each with its own important sources and functions in the body.

Are there any side effects from taking Menakion MM?

High doses of phylloquinone may in some cases cause adverse effects such as nausea, vomiting, diarrhea, and an increased risk of bruising. Additionally, because Menakion MM can interfere with the effectiveness of certain medications, it is important to speak with a healthcare professional before taking a supplement.

Can I get Menakion MM naturally from food?

Yes, Menakion MM can be obtained naturally from food, and this is the best way for most people to get the recommended daily amount. Dark green leafy vegetables such as kale, spinach, Swiss chard, broccoli, cabbage, cauliflower, Brussels sprouts, and collard greens are some of the best sources of phylloquinone.

Can Menakion MM be taken in combination with other vitamins?

Yes, Menakion MM can be taken in combination with other vitamins safely. It is important to consult with a healthcare professional before taking any dietary supplement to make sure that dosage is appropriate and safe.

Are there any foods or drinks that I should avoid if I'm taking Menakion MM?

Alcohol can reduce the amount of phylloquinone absorbed by the body, so it is best to limit alcohol consumption if you take a phylloquinone supplement. Additionally, it is important to speak to your doctor before taking any medications or supplements as they can interfere with the effectiveness of phylloquinone.

Does Menakion MM affect the menstrual cycle?

Research has not conclusively shown that phylloquinone has any direct effects on the menstrual cycle. However, it is important to speak to your doctor before taking any supplement as it can have an effect on other hormones and medications.

How do I know if I'm deficient in Menakion MM?

Common signs of a phylloquinone deficiency include easy bruising and bleeding, fatigue, and numbness or tingling in the extremities. If you experience any of these symptoms it is important to speak with your doctor to determine if you are indeed deficient in phylloquinone.

Can Menakion MM help make my bones stronger?

Menakion MM plays an important role in bone health, as it helps the body absorb and utilize calcium. Additionally, it is an antioxidant and may help protect against age-associated diseases. However, it is important to remember that vitamins and minerals can only do so much - regular exercise and nutritious eating habits are also important for bone health.

Where can I get Menakion MM?

Menakion MM is found in dark green leafy vegetables such as kale, spinach, Swiss chard, broccoli, cabbage, cauliflower, Brussels sprouts, and collard greens. It is also available in dietary supplement form in stores that carry vitamins and supplements.

Can Menakion MM help with osteoporosis prevention?

Yes, research has shown that there is a link between higher intakes of vitamin K (phylloquinone) and lower risks of osteoporosis. However, as with any supplement, it is important to consult with your doctor before taking it to make sure it is appropriate and safe.

Does Menakion MM have any interaction with other medications?

Yes, Menakion MM can interact with certain medications, including antibiotics, anticoagulants, and anti-seizure medications. It is important to speak to your doctor before taking any supplement to make sure it is appropriate and safe to take with your medication.

Are there any medical conditions associated with Menakion MM deficiency?

Yes, Menakion MM deficiency can lead to a condition called Vitamin K deficiency bleeding (VKDB), which is a bleeding disorder that can affect infants, children, and adults. It is important to speak to your doctor if you have any signs or symptoms associated with a Vitamin K deficiency.

What are some natural sources of Menakion MM?

Dark green leafy vegetables such as kale, spinach, Swiss chard, broccoli, cabbage, cauliflower, Brussels sprouts, and collard greens are some of the best natural sources of phylloquinone. It can also be found in certain fruits such as kiwi, grapes, and pineapple.

Can Menakion MM be taken with other vitamins and supplements?

Yes, Menakion MM can be taken in combination with other vitamins and supplements. It is important to talk to your doctor before taking any dietary supplement or medication to make sure the dosages are safe and appropriate.

Does Menakion MM help to prevent cancer?

Research has suggested that phylloquinone may have a role in cancer prevention due to its antioxidant properties. However, more research is needed to fully understand the relationship between phylloquinone and cancer prevention.

Does Menakion MM have any side effects?

High doses of phylloquinone may in some cases cause adverse effects such as nausea, vomiting, diarrhea, and an increased risk of bruising. Additionally, because Menakion MM can interfere with the effectiveness of certain medications, it is important to speak with a healthcare professional before taking a supplement.

Does Menakion MM increase blood clotting?

Yes, Menakion MM is involved in the blood clotting process. It helps the body form a protein that is essential for normal blood clotting.

Can Menakion MM be taken while pregnant or breastfeeding?

It is important to speak to your doctor before taking any dietary supplement while pregnant or breastfeeding. High doses of phylloquinone may cause side effects such as nausea and vomiting which could be dangerous for a pregnant or nursing woman.

What happens if I don't get enough Menakion MM?

A deficiency in phylloquinone can lead to a condition called Vitamin K deficiency bleeding (VKDB), which is a bleeding disorder that can affect infants, children, and adults. Common signs of a deficiency include easy bruising and bleeding, fatigue, and numbness or tingling in the extremities.

Does Menakion MM have anti-ageing effects?

Menakion MM is an antioxidant and may help protect against age-associated diseases. Additionally, it helps the body absorb and utilize calcium, which is important for bone and joint health as you age.

Does Menakion MM help with bone and joint health?

Yes, Menakion MM plays an important role in bone health, as it helps the body absorb and utilize calcium. It is also an antioxidant, which may help protect against age-associated diseases such as osteoporosis. However, it is important to remember that vitamins and minerals can only do so much - regular exercise and nutritious eating habits are also important for bone health.

How long does it take for Menakion MM to start working?

The effects of phylloquinone can vary from person to person. Generally speaking, it may take several weeks for the effects of phylloquinone to be felt, but it is important to consult with your doctor or healthcare professional to determine the right dosage for you.

Is it safe to take Menakion MM supplements?

Yes, Menakion MM is safe to take as a dietary supplement in the recommended dosages. However, it is important to speak to your doctor before taking any supplement or medication to ensure that the dosages are safe and appropriate.

Is Menakion MM the same as Vitamin K2?

No, Menakion MM (vitamin K1) is different from Vitamin K2 (menaquinone). Although they both serve similar functions, their sources and absorption methods are different. Vitamin K2 is found primarily in animal-based foods such as eggs, liver, and fermented dairy products, while Vitamin K1 is found primarily in dark green leafy vegetables.

Does Menakion MM have any effect on the kidneys?

Research has not conclusively shown any direct effect of phylloquinone on the kidneys. However, it is important to consult with your doctor before taking any supplement to make sure that it does not interfere with any medications you may be taking.

Should I take Menakion MM everyday?

It is important to speak to your doctor before taking any dietary supplement or medication. Depending on your doctor’s instructions, it may be advisable to take phylloquinone every day in order to meet the recommended daily intake.

Is Menakion MM tied to any health risks?

High doses of Menakion MM may cause adverse effects such as nausea, vomiting, diarrhea, and an increased risk of bruising. Additionally, because Menakion MM can interfere with the effectiveness of certain medications, it is important to speak with a healthcare professional before taking a supplement.

What is the difference between Menakion MM and Vitamin K2?

Menakion MM (vitamin K1) and Vitamin K2 (menaquinone) are both vitamers of Vitamin K, which serve similar functions in the body. Vitamin K1 is found primarily in dark green leafy vegetables, while Vitamin K2 is found primarily in animal-based foods such as eggs, liver, and fermented dairy products.

Does the body store Menakion MM?

No, the body does not store Menakion MM, so it is important to obtain it through dietary sources or supplements. Menakion MM is found in dark green leafy vegetables such as kale, spinach, Swiss chard, broccoli, cabbage, cauliflower, Brussels sprouts, and collard greens.

Does Menakion MM have any effect on cholesterol levels?

Research has suggested that higher intakes of phylloquinone may be linked to lower levels of total cholesterol, as well as low-density lipoprotein (LDL), or “bad” cholesterol. However, more research is needed to confirm this potential link.

Can Menakion MM be toxic if taken in large amounts?

Yes, phylloquinone can be toxic if taken in large amounts, and it is important to consult with your doctor before taking a supplement. High doses of phylloquinone may in some cases cause adverse effects such as nausea, vomiting, diarrhea, and an increased risk of bruising.

What happens if

https://www.medicinesfaq.com/brand/menakion-mm, http://classyfire.wishartlab.com/tax_nodes/C0000000, http://classyfire.wishartlab.com/tax_nodes/C0000012, http://classyfire.wishartlab.com/tax_nodes/C0000259, http://classyfire.wishartlab.com/tax_nodes/C0001534, http://classyfire.wishartlab.com/tax_nodes/C0001547, http://classyfire.wishartlab.com/tax_nodes/C0001551, http://classyfire.wishartlab.com/tax_nodes/C0000153, http://classyfire.wishartlab.com/tax_nodes/C0002495, http://classyfire.wishartlab.com/tax_nodes/C0003670, http://classyfire.wishartlab.com/tax_nodes/C0003940, http://classyfire.wishartlab.com/tax_nodes/C0004150, https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:18067, http://www.lipidmaps.org/data/LMSDRecord.php?LMID=LMPR02030028, http://www.hmdb.ca/metabolites/HMDB0015157, http://www.genome.jp/dbget-bin/www_bget?drug:D00148, http://www.genome.jp/dbget-bin/www_bget?cpd:C02059, https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=5284607, https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46504528, https://www.chemspider.com/Chemical-Structure.4447652.html, http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24782, https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=8308, https://www.ebi.ac.uk/chebi/searchId.do?chebiId=18067, https://www.ebi.ac.uk/chembldb/index.php/compound/inspect/CHEMBL1550, https://zinc.docking.org/substances/ZINC000003831332, http://bidd.nus.edu.sg/group/cjttd/ZFTTDDRUG.asp?ID=DNC001500, http://www.pharmgkb.org/drug/PA450961, https://www.ebi.ac.uk/pdbe-srv/pdbechem/chemicalCompound/show/PQN, http://www.rxlist.com/cgi/generic3/phytonadione.htm, https://www.drugs.com/cdi/phytonadione.html, https://en.wikipedia.org/wiki/Phytomenadione,