Maxitrol
Maxitrol Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Maxitrol is a brand name. Its generic name is Dexamethasone + neomycin + polymyxin b.
Introduction
Dexamethasone + Neomycin + Polymyxin B is a combination antibiotic and glucocorticoid medication used to treat a wide variety of infections. It is a combination of an antibiotic (neomycin) and two corticosteroids (dexamethasone and polymyxin B).Uses For
Dexamethasone + Neomycin + Polymyxin B is used to treat a variety of bacterial infections including skin infections, eye infections, middle ear infections, upper respiratory tract infections, and certain vaginal infections.Mechanism of Action
Dexamethasone + Neomycin + Polymyxin B works by attacking an infection by inhibiting the growth of bacteria. The glucocorticoid dexamethasone reduces inflammation and modifies the body’s response to infection. The antibiotic neomycin inactivates the infecting bacterium by blocking its ability to synthesize essential proteins. Polymyxin B is a polypeptide antibiotic. It works by forming pores in the bacterial cell membrane and inhibiting bacterial growth.How Long Does it Take to Work?
It typically takes around five to seven days for an infection treated with Dexamethasone + Neomycin + Polymyxin B to show improvement. The length of treatment time may vary depending on the severity of the infection.Absorption
Dexamethasone is readily absorbed following administration, with peak serum levels observed after two to four hours. Neomycin and polymyxin B are not absorbed or distributed systemically following topical application.Route of Elimination
Dexamethasone is eliminated from the body through the renal system. Neomycin and polymyxin B are eliminated through the kidneys and feces, respectively.Dosage
The recommended dose for Dexamethasone + Neomycin + Polymyxin B is 0.75 gram per ear or 0.5 gram per eye twice daily.Administration
Dexamethasone + Neomycin + Polymyxin B may be administered topically as a lotion, ointment, or drops, depending on the infection being treated.Side Effect
Common side effects include, but are not limited to, burning, stinging, redness, irritation, dryness, soreness, or itching.Toxicity
Dexamethasone is considered toxic at doses higher than those recommended for use in humans. Neomycin and polymyxin B are considered minimally toxic and rarely cause serious side effects when used topically.Precaution
Patients should not use Dexamethasone + Neomycin + Polymyxin B if they have any pre-existing allergies to antibiotics or glucocorticoids, or if they are pregnant or lactating. Patients should also consult their healthcare provider before using this medication if they have diabetes, glaucoma, or are taking any other medications.Interaction
Dexamethasone + Neomycin + Polymyxin B can interact with certain medications, including insulin, antifungals, blood thinners, and other antibiotics. Patients should inform their healthcare provider of any other medications they may be taking before using this medication.Disease Interaction
Patients with a history of tuberculosis, acid reflux, herpes simplex, smallpox, or HIV should consult a healthcare provider prior to use.Drug Interaction
Dexamethasone + Neomycin + Polymyxin B can interact with certain drugs, including isotretinoin, barbiturates, antibiotics, anticonvulsants, and anticoagulants. Patients should inform their healthcare provider of any other medications they are taking before using this medication.Food Interaction
Foods containing dairy, vitamins, or iron can affect the absorption of some antibiotics and corticosteroids.Pregnancy Use
Dexamethasone + Neomycin + Polymyxin B is classified as a pregnancy category C drug, meaning that it is not recommended for use in pregnant women.Lactation Use
Dexamethasone + Neomycin + Polymyxin B should not be used by breastfeeding women due to the risk of passing the medication to the infant through breast milk.Acute Overdose
Signs of an acute overdose include nausea, vomiting, and difficulty breathing. An acute overdose should be treated with supportive care.Contraindication
Dexamethasone + Neomycin + Polymyxin B should not be used in patients with known hypersensitivity to antibiotics or glucocorticoids.Use Direction
Dexamethasone + Neomycin + Polymyxin B should be used as directed by a healthcare provider.Storage Condition
Dexamethasone + Neomycin + Polymyxin B should be stored at room temperature, away from direct sunlight and heat.Volume of Distribution
The volume of distribution of dexamethasone is 3.3 to 6.6 L/kg.Half Life
The half-life of dexamethasone is 36 to 54 hours.Clearance
The clearance of dexamethasone is 0.88 to 1.76 L/h/kg.Here you find in details version of Maxitrol
Some Frequently Asked Questions About Maxitrol
What is Dexamethasone + Neomycin + Polymyxin B?
Dexamethasone + Neomycin + Polymyxin B is a combination medication used to treat bacterial infections of the outer ear. It contains dexamethasone, an anti-inflammatory steroid, neomycin, an antibiotic, and polymyxin B, an antibacterial.
How does Dexamethasone + Neomycin + Polymyxin B work?
Dexamethasone works by reducing inflammation and decreasing swelling. Neomycin and polymyxin B work together to fight off the bacterial infection. They stop the bacteria from growing and multiplying so that the body can fight off the infection.
What are the side effects of Dexamethasone + Neomycin + Polymyxin B?
The most common side effects of dexamethasone + neomycin + polymyxin B include itching, stinging, burning, pain, or redness in the affected area. Other less common side effects include rashes, upset stomach, nausea, vomiting, and diarrhea.
How should I take Dexamethasone + Neomycin + Polymyxin B?
Dexamethasone + Neomycin + Polymyxin B should be taken as directed by your doctor. For ear infections, the solution should be instilled into the affected ear two to four times daily for seven days. Gently pull the ear back to open the ear canal before administering the drops.
What should I avoid while taking Dexamethasone + Neomycin + Polymyxin B?
Avoid getting the solution in your eyes, nose, or mouth. If it does get in these areas, rinse with plenty of cool water. Avoid using other ear medications while using Dexamethasone + Neomycin + Polymyxin B unless specifically prescribed by your doctor.
What happens if I miss a dose of Dexamethasone + Neomycin + Polymyxin B?
If you miss a dose of Dexamethasone + Neomycin + Polymyxin B, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the next dose as scheduled. Do not take two doses at the same time.
Is Dexamethasone + Neomycin + Polymyxin B safe for pregnant women?
Dexamethasone + Neomycin + Polymyxin B is generally considered safe for use in pregnant women. However, it is important to talk to your doctor before taking any medication during pregnancy.
Is Dexamethasone + Neomycin + Polymyxin B safe for children?
Yes, Dexamethasone + Neomycin + Polymyxin B is safe for use in children. Follow your doctor’s instructions when giving this medication to a child.
What should I do if I experience an allergic reaction to Dexamethasone + Neomycin + Polymyxin B?
Stop taking Dexamethasone + Neomycin + Polymyxin B and seek emergency medical help if you experience signs of an allergic reaction such as difficulty breathing, hives, swelling of the face, lips, tongue, or throat.
Is Dexamethasone + Neomycin + Polymyxin B a steroid?
Yes, Dexamethasone + Neomycin + Polymyxin B contains dexamethasone, an anti-inflammatory steroid.
Is Dexamethasone + Neomycin + Polymyxin B available over-the-counter?
No, Dexamethasone + Neomycin + Polymyxin B is a prescription medication and is not available over-the-counter.
What is the usual dosage of Dexamethasone + Neomycin + Polymyxin B?
The usual dosage of dexamethasone + neomycin + polymyxin B is 0.05 mL instilled into the affected ear two to four times daily for seven days.
How long does it take for Dexamethasone + Neomycin + Polymyxin B to work?
It may take several days for Dexamethasone + Neomycin + Polymyxin B to take effect. Improvement in symptoms should be seen within a few days of starting treatment, but it may take several days for the infection to be fully cleared.
Is Dexamethasone + Neomycin + Polymyxin B the same as Ciprodex?
No, Dexamethasone + Neomycin + Polymyxin B and Ciprodex are not the same. Ciprodex is a combination medication used to treat bacterial infections of the ear. It contains ciprofloxacin, an antibiotic, and dexamethasone, an anti-inflammatory steroid.
Is Dexamethasone + Neomycin + Polymyxin B safe for use in dogs?
Yes, Dexamethasone + Neomycin + Polymyxin B is safe for use in dogs. However, it is important to use the medication only as directed by your veterinarian.
Can Dexamethasone + Neomycin + Polymyxin B be used to treat other types of infections?
No, Dexamethasone + Neomycin + Polymyxin B is specifically indicated for the treatment of bacterial infections of the outer ear. It should not be used for other types of infections.
Can I buy Dexamethasone + Neomycin + Polymyxin B online?
No, Dexamethasone + Neomycin + Polymyxin B is a prescription medication and it is not legal to buy it online without a prescription.
What should I do if my ear infection has not improved after taking Dexamethasone + Neomycin + Polymyxin B?
If your ear infection has not improved after taking Dexamethasone + Neomycin + Polymyxin B, consult your doctor. Your doctor may prescribe a different type of medication or suggest other treatment options.
Does Dexamethasone + Neomycin + Polymyxin B need to be refrigerated?
No, Dexamethasone + Neomycin + Polymyxin B does not need to be refrigerated. Store it at room temperature away from heat and moisture.
Is there a generic form of Dexamethasone + Neomycin + Polymyxin B?
No, there is not a generic form of Dexamethasone + Neomycin + Polymyxin B available. This medication is only available in its brand-name form.
What happens if I overdose on Dexamethasone + Neomycin + Polymyxin B?
If you overdose on Dexamethasone + Neomycin + Polymyxin B, seek emergency medical attention or call Poison Control (1-800-222-1222). Overdoses of this medication can be fatal.
Who should not take Dexamethasone + Neomycin + Polymyxin B?
Dexamethasone + Neomycin + Polymyxin B should not be used by people with a known allergy or hypersensitivity to any of the ingredients. It should also be avoided in people with a history of tympanostomy tubes.
Can Dexamethasone + Neomycin + Polymyxin B be used in conjunction with other medications?
Yes, Dexamethasone + Neomycin + Polymyxin B can be used in conjunction with other medications. However, it is important to talk to your doctor before taking any other medications with Dexamethasone + Neomycin + Polymyxin B.
What is the difference between Dexamethasone + Neomycin + Polymyxin B and Dexamethasone + Neomycin?
The difference between Dexamethasone + Neomycin + Polymyxin B and Dexamethasone + Neomycin is that Dexamethasone + Neomycin + Polymyxin B also contains polymyxin B, an antibacterial. Dexamethasone + Neomycin is used for inflammatory conditions, while Dexamethasone + Neomycin + Polymyxin B is specifically used to treat bacterial infections of the outer ear.
Is it normal to experience some pain and discomfort after using Dexamethasone + Neomycin + Polymyxin B?
Yes, it is normal to experience some pain and discomfort after using Dexamethasone + Neomycin + Polymyxin B. This should resolve within a few days of starting treatment. If the pain or discomfort persists or becomes severe, consult your doctor.
Can I use Dexamethasone + Neomycin + Polymyxin B for swimmer's ear?
Yes, Dexamethasone + Neomycin + Polymyxin B can be used for swimmer’s ear. It is specifically indicated for the treatment of bacterial infections of the outer ear.
Is it safe to use Dexamethasone + Neomycin + Polymyxin B while breastfeeding?
Yes, it is generally considered safe to use Dexamethasone + Neomycin + Polymyxin B while breastfeeding. However, it is important to talk to your doctor before taking any medication while breastfeeding.
Can Dexamethasone + Neomycin + Polymyxin B be used to treat an inner ear infection?
No, Dexamethasone + Neomycin + Polymyxin B is specifically indicated for the treatment of bacterial infections of the outer ear. It should not be used to treat an inner ear infection.
Is Dexamethasone + Neomycin + Polymyxin B used to treat yeast infections?
No, Dexamethasone + Neomycin + Polymyxin B is not used to treat yeast infections. This medication is specifically indicated for the treatment of bacterial infections of the outer ear.
Does Dexamethasone + Neomycin + Polymyxin B need to be taken with food?
No, Dexamethasone + Neomycin + Polymyxin B does not need to be taken with food. It should be taken as directed by your doctor.
What form(s) does Dexamethasone + Neomycin + Polymyxin B come in?
Dexamethasone + Neomycin + Polymyxin B comes in an otic suspension form. This medication is available in a 15 mL bottle.
Does Dexamethasone + Neomycin + Polymyxin B cause drowsiness?
No, Dexamethasone + Neomycin + Polymyxin B does not typically cause drowsiness. If you experience drowsiness or dizziness while taking this medication, talk to your doctor.
Is Dexamethasone + Neomycin + Polymyxin B the same as Hydrocortisone?
No, Dexamethasone + Neomycin + Polymyxin B and Hydrocortisone are not the same. Hydrocortisone is an anti-inflammatory steroid used to treat inflammatory skin conditions. Dexamethasone + Neomycin + Polymyxin B is used to treat bacterial infections of the outer ear.
Can I use Dexamethasone + Neomycin + Polymyxin B if I have a cold or flu?
No, Dexamethasone + Neomycin + Polymyxin B is not indicated for the treatment of colds or the flu. It is specifically indicated for the treatment of bacterial infections of the outer ear.