Lozide

Lozide Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Lozide is a brand name. Its generic name is Gliclazide.

Introduction

Lozide (also known as glyburide) is an oral anti-diabetic medication used to treat type 2 diabetes. It works by encouraging the release of insulin and lowering the blood sugar levels. It may also be used for other conditions as determined by your doctor.

Uses for

Lozide is used to treat type 2 diabetes by helping to lower the blood sugar levels. It is usually prescribed after other diabetes medications have been tried without successful treatment of symptom.

Mechanism of Action

Lozide works to treat type 2 diabetes by increasing the effect of insulin, which signals the body to lower the blood sugar level. It can help control glucose levels by increasing the release of insulin and reducing the amount of sugar produced by the liver.

How Long Does it Take to Work?

The duration of action of gliclazide is usually 6 to 12 hours, however it can take up to two weeks for it to reach its maximal effect.

Absorption

Lozide is rapidly absorbed in the gastrointestinal tract. It is mainly absorbed in the small intestine, with some absorption in the stomach.

Route of Elimination

Lozide is eliminated mainly through the kidneys. Approximately 70-90% of it is excreted unchanged in the urine.

Dosage

For adults, the recommended starting dose is 30-60mg once daily before the morning meal. The dose can be increased by 30-60mg every 1-2 weeks until the desired blood sugar levels have been achieved. It is important to take the same amount and time of dose each day.

Administration

Lozide should be taken as directed by your doctor, usually once daily before a meal. It should be swallowed whole with a glass of water.

Side Effect

Lozide can cause side effects such as nausea, vomiting, dizziness, headache, blurred vision, paleness, stomach pain, loss of appetite, diarrhea, lightheadedness, fatigue, and constipation.

Toxicity

Lozide is considered to be a low toxicity medication. In case of overdose, symptomatic and supportive treatment should be provided.

Precautions

Lozide can interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.

Interaction

Lozide can interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.

Disease Interaction

Lozide may interact with certain diseases and conditions such as liver, kidney, or heart disease; thyroid disorders; and asthma. It is important to tell your doctor about all of your medical conditions before taking gliclazide.

Drug Interactions

Lozide may interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.

Food Interactions

Lozide can interact with certain foods and beverages and increase the risk of side effects. It is important to avoid foods high in sugar and fat while taking gliclazide.

Pregnancy Use

Lozide should not be used during pregnancy. Consult your doctor about the potential risks and benefits of taking gliclazide during pregnancy.

Lactation Use

It is unknown whether gliclazide is excreted in breast milk. It is recommended to avoid taking gliclazide while breastfeeding.

Acute Overdose

In case of an acute overdose of gliclazide, symptomatic and supportive treatment should be provided.

Contraindication

Lozide should not be used in patients with diabetic ketoacidosis, type 1 diabetes, type 3 diabetes, and in those allergic to it.

Use Direction

Lozide should be taken exactly as prescribed by your doctor. Do not increase or decrease the dose, or take the medication for a longer period of time than prescribed.

Storage Conditions

Lozide should be stored at room temperature, away from direct sunlight, heat and moisture. It should be kept out of the reach of children and pets.

Volume of Distribution

The volume of distribution of gliclazide is approximately 20-50 L/kg.

Half life

The elimination half-life of gliclazide is 1.5-4.5 hours.

Clearance

The clearance of gliclazide in adults is 0.15-0.3 ml/min/kg.

Here you find in details version of Lozide

Some Frequently Asked Questions About Lozide

What is Lozide?

Lozide is a medication which belongs to the group of medicines called sulfonylureas. It is used to control blood glucose levels in people with type 2 diabetes.

How does Lozide work?

Lozide works by increasing the amount of insulin that is released by the pancreas which helps to control blood glucose levels in people with Type 2 diabetes.

What are the uses of Lozide?

Lozide is used to control blood glucose levels in people with Type 2 diabetes.

What are the side effects of Lozide?

Lozide may cause some side effects, including headache, nausea, weight gain, tiredness, and some skin rashes.

Does Lozide cause hypoglycemia?

Yes, Lozide can cause hypoglycemia, which is a condition where the blood glucose levels become too low. Symptoms of hypoglycemia include sweating, hunger, shakiness, dizziness, and confusion.

How should Lozide be taken?

Lozide should be taken orally usually once or twice a day as directed by your doctor.

How long does it take for Lozide to work?

Lozide usually starts to work within 1-2 hours after it is taken.

Does Lozide need to be taken with food?

No, Lozide does not need to be taken with food. It can be taken before, with, or after meals.

What is the recommended dose of Lozide?

The recommended dose of Lozide depends on the individual and the type of diabetes. It is important to follow the instructions of your doctor or pharmacist.

What should I do if I forget to take Lozide?

If you forget to take Lozide, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose. Do not double your dose.

Should I avoid alcohol while taking Lozide?

Yes, it is recommended to avoid alcohol while taking Lozide as it can increase the risk of adverse effects such as low blood sugar.

Can Lozide be taken while pregnant or breastfeeding?

Lozide should not be taken while pregnant or breastfeeding. Speak to your doctor before taking any medication while pregnant or breastfeeding.

What foods should I avoid while taking Lozide?

It is important to follow a healthy and balanced diet while taking Lozide. Avoid foods high in sugar, fat, and cholesterol.

Is Lozide available as a generic medication?

Yes, Lozide is available as a generic medication.

What other medications should not be taken with Lozide?

Certain medications can interact with Lozide and should not be taken together. This includes ACE inhibitors, diuretics, sulfonamides, cimetidine, and other sulfonylureas.

Can I take Lozide with metformin?

Yes, Lozide can be taken with metformin. It is important to take both medications as prescribed by your doctor.

Are there any alternatives to Lozide?

Yes, there are other medications available to control blood glucose levels. Speak to your doctor or pharmacist about other alternatives.

Can Lozide be used to treat type 1 diabetes?

No, Lozide is not suitable for use in people with type 1 diabetes.

Does Lozide cause weight gain?

Lozide can cause weight gain in some cases. It is important to follow a healthy and balanced diet and to exercise regularly.

What should I do if I experience side effects while taking Lozide?

If you experience side effects while taking Lozide, speak to your doctor or pharmacist. They may be able to suggest a change in dosage or medication to help alleviate the side effects.

Can diabetic ketoacidosis occur while taking Lozide?

Yes, diabetic ketoacidosis can occur while taking Lozide. Symptoms include dry mouth, thirst, fatigue, fruity odor on breath, and rapid breathing.

How should Lozide be stored?

Lozide should be stored at room temperature away from direct sunlight and heat. Do not keep Lozide in the refrigerator or freezer.

Can I overdose on Lozide?

Yes, it is possible to overdose on Lozide. If you or someone you know has taken an overdose, call your local poison control center or emergency services immediately.

Can I donate blood while taking Lozide?

No, it is recommended that you do not donate blood while taking Lozide.

Can I take Lozide if I have kidney disease?

It is recommended that you speak to your doctor before taking Lozide if you have kidney disease. Your doctor may recommend a different medication.

Is Lozide a blood thinner?

No, Lozide is not a blood thinner. It is used to control blood glucose levels in people with Type 2 diabetes.

Can Lozide be used to treat Type 1 diabetes?

No, Lozide is not suitable for use in people with Type 1 diabetes.

Can Lozide cause low blood pressure?

Yes, Lozide can cause low blood pressure, which can cause dizziness, lightheadedness, and fainting.

Can I take Lozide while taking other medications?

It is important to let your doctor know about all medications that you are taking before taking Lozide. Certain medications can interact with Lozide.

Does Lozide raise cholesterol levels?

Yes, Lozide can raise cholesterol levels. It is important to follow a healthy and balanced diet to help maintain healthy cholesterol levels.

Is Lozide a steroid?

No, Lozide is not a steroid. It is used to control blood glucose levels in people with Type 2 diabetes.

Does Lozide cause diarrhea?

Yes, Lozide can cause diarrhea. If you experience diarrhea while taking Lozide, speak to your doctor or pharmacist.

Can I take Lozide with ibuprofen?

It is recommended that you do not take Lozide with ibuprofen as it may increase the risk of adverse effects. Speak to your doctor before taking any medications together.

Can I take Lozide with muscle relaxers?

It is recommended that you do not take Lozide with muscle relaxers as it may increase the risk of adverse effects. Speak to your doctor before taking any medications together.

What should I do if I miss a dose of Lozide?

If you miss a dose of Lozide, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose. Do not double your dose.

Can I take Lozide while breastfeeding?

No, it is recommended that you do not take Lozide while breastfeeding. Speak to your doctor before taking any medications while breastfeeding.

Can I take Lozide while pregnant?

No, it is recommended that you do not take Lozide while pregnant. Speak to your doctor before taking any medications while pregnant.

Can Lozide cause headaches?

Yes, Lozide can cause headaches in some people. If you experience headaches while taking Lozide, speak to your doctor or pharmacist.

Can I take Lozide with other diabetes medications?

Yes, Lozide can be taken with other diabetes medications. It is important to follow the instructions of your doctor or pharmacist.

What should I do if I experience low blood sugar while taking Lozide?

If you experience low blood sugar while taking Lozide, it is important to eat or drink something sugary, such as fruit juice, honey, candy, or a glucose tablet. It is also important to speak to your doctor or pharmacist.

Are there any foods that I should avoid while taking Lozide?

It is important to follow a healthy and balanced diet while taking Lozide. Avoid foods high in sugar, fat, and cholesterol.

How long can I take Lozide for?

The length of time that you take Lozide for depends on the individual and the type of diabetes. It is important to follow the instructions of your doctor or pharmacist.

Is Lozide a controlled substance?

No, Lozide is not a controlled substance.