Lotrel G
Lotrel G Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Lotrel G is a brand name. Its generic name is Loteprednol Etabonate + Gatifloxacin.
Introduction
Lotrel G is a prescription medication used to treat bacterial infections of the eyes. It is a combination of a steroid and an antibiotic. It is used to reduce inflammation and pain while fighting the infection.Uses
Lotrel G is prescribed for the treatment of bacterial conjunctivitis infections of the eyes. It is used to reduce pain, redness, itching and discomfort associated with eye infections.Mechanism of Action
Lotrel G works by reducing inflammation in the eye and preventing the growth and spread of bacterial infections. The steroid component of the medication works to reduce swelling and pain associated with the infection. The antibiotic component works to kill the bacteria responsible for the infection.How Long Does It Take To Work
It may take several days of regular use before the full effects of Lotrel G can be seen. Generally, improvement should be noticed within the first few days.Absorption, Route of Elimination, Dosage & Administration
Lotrel G is administered directly into the eyes. It is absorbed through the corneal membrane and is then taken up into the conjunctiva and the anterior chamber of the eye. It is slowly metabolized and eliminated in the urine. Dosage of Lotrel G will be determined by a healthcare provider. It is usually prescribed as one drop placed into the affected eye four times a day, for a total of four drops per day.Side Effects
Common side effects of Lotrel G include blurred vision, burning sensation in the eyes, and dry eyes. Other more serious side effects may include allergic reactions, blurred vision, pain, redness, swelling and irritation.Toxicity
Lotrel G is generally considered safe and well tolerated when used as directed. Serious toxicity and reactions occur rarely.Precautions
Contact lenses should not be worn while using Lotrel G. It is important to use the medication as directed by a healthcare provider. Do not use more or less than is recommended. Overuse of the medication can lead to serious side effects.Interaction
Lotrel G may interact with other medications including alcohol, antacids, and other medications used to treat eye issues. It is important to tell a healthcare provider about all medications, supplements and herbs being taken before using Lotrel G.Disease Interaction
Lotrel G is not recommended for use by individuals with certain diseases or conditions. These include an allergy to Loteprednol Etabonate and Gatifloxacin, an eye infection, and an impaired immune system.Drug Interaction
Lotrel G may interact with other drugs including blood thinners, steroids, and other eye medications. It is important to tell a healthcare provider about all medications, supplements, and herbs being taken.Food Interactions
No food interaction information is available.Pregnancy Use
Lotrel G should be used with caution during pregnancy. It is not recommended for use if pregnant unless the potential benefit outweighs the risk for the unborn child.Lactation Use
Lotrel G is not recommended for use while breastfeeding. It is important to talk to a healthcare provider before taking any medications while breastfeeding.Acute Overdose
If an overdose is suspected, seek immediate medical attention. Symptoms of overdose may include blurry vision and eye irritation.Contraindication
Lotrel G is contraindicated in certain individuals including those with a known allergy to Loteprednol Etabonate and Gatifloxacin, individuals with an eye infection, and those with an impaired immune system.Use Directions
Lotrel G is intended for use in the eyes only. Do not use the eye drops in the mouth or nose. Avoid contact with fingertips while using the medication.Storage Condition
Lotrel G should be stored at room temperature, away from light and moisture. Do not freeze the medication. Throw away any unused medication after the expiration date.Volume of Distribution
Lotrel G has a volume of distribution of 3.23 L/kg.Half Life
The half life of Lotrel G is approximately 4 to 5 hours.Clearance
Loteprenol Etabonate + Gatifloxacin has a clearance of approximately 5.48 L/hr/kg.Here you find in details version of Lotrel G