Lopidam
Lopidam Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Lopidam is a brand name. Its generic name is Iopamidol.
**Lopidam Introduction** Lopidam is an intravenous (IV) radiographic (X-ray dye) contrast agent used to improve the visibility of organs, blood vessels, or tissues during certain X-ray tests and procedures. It ENHANCES the visibility of the target area and brighter shade on an x-ray. It helps doctors to see the area more clearly. **Uses for Lopidam** Lopidam is used to improve the visibility of structures in X-rays such as organs, blood vessels, and tissues. It is mainly used to detect or monitor diseases of the abdominal organs, lungs, and central nerves in different types of imaging. It is also used to detect blood clot or blockage in an artery or vein. Furthermore, it can be used to examine the anatomy in catscan or MRI studies. **Mechanism of Action** Lopidam works by coating a target structure with an odorless, clear, and iodine-rich compound. When this compound is exposed to X-ray beams, it absorbs the radiation and leaves a bright outline of the target area. The X-ray image created is much brighter and clearer than a regular X-ray. **How Long Does It Take to Work?** Lopidam usually starts to work within a few minutes of administration. **Absorption** Lopidam is not absorbed systemically and is rapidly cleared from the body through the kidneys. **Route of Elimination** Lopidam is eliminated primarily by the kidneys as unchanged drug or its metabolites. **Dosage** The dosage of Lopidam depends on the patient’s weight, the procedure being performed, and the doctor’s instructions. Dosage information is provided by the manufacturer and is usually based on body weight for adults and children over 12 years. The typical adult dose of Lopidam ranges from 0.3 to 0.6 mL/kg body weight and is given as an intravenous solution. **Administration** Lopidam is administered as an intravenous injection into a vein. **Side Effect** Common side effects of Lopidam include chest pain, nausea, rapid heart rate, headache, and flushing. **Toxicity** Lopidam is generally considered safe when used as directed. However, it can cause serious side effects if taken in large doses or with medications that interact with it. **Precautions** Some people may have an allergic reaction to Lopidam. People with kidney or liver disease, congestive heart failure, or any other condition that affects the kidneys should be monitored closely. It is important to alert your doctor if you are allergic to iodine or are sensitive to X-ray dyes. **Interaction** Lopidam may interact with certain medications. Talk to your doctor before using Lopidam and any other medication. **Disease Interaction** Lopidam should not be used in patients with certain diseases or conditions, such as severe kidney or liver disease, bladder outlet obstruction, or glandular fever. **Drug Interaction** Lopidam may interact with certain medications, such as allopurinol, amiodarone, and chemotherapies. Tell your doctor about all the medications you are taking before using Lopidam. **Food Interactions** There are no known food interactions with Lopidam. **Pregnancy Use** Lopidam should not be used during pregnancy unless the benefits outweigh the risks. **Lactation Use** Lopidam should not be used while breastfeeding due to the potential for toxicity in nursing infants. **Acute Overdose** An overdose of Lopidam may cause severe nausea, abdominal pain, and dysphagia. In cases of overdose, call the Poison Control Center at 1-800-222-1222 or seek immediate medical attention. **Contraindication** Lopidam should not be used in patients who are allergic to iodine or X-ray dyes, or who have severe kidney or liver disease. **Use Direction** Lopidam is administered intravenously as an injection into a vein. It should be used only when prescribed by a doctor and must be administered by a qualified health care professional. **Storage Condition** Lopidam should be stored at room temperature away from light and moisture. It should be disposed of in accordance with local regulations. **Volume of Distribution** Lopidam is not distributed systemically and has no estimated volume of distribution. **Half Life** The half life of Lopidam is approximately 2.05 hours (125 minutes). **Clearance** The clearance of Lopidam is approximately 9.51 mL/min/kg.Here you find in details version of Lopidam
Some Frequently Asked Questions About Lopidam
What is Lopidam?
Lopidam is an iodinated contrast media used in x-ray and computed tomography (CT scan) examinations of the brain, spine, and body to help visualize details of internal organs and structures.
How does Lopidam work?
Lopidam works by temporarily blocking x-rays, making certain organs or tissues clearer and easier to see on the image.
When is Lopidam used?
Lopidam is used to help distinguish between normal and abnormal areas of the body in x-ray and CT scan examinations. It is used to help diagnose diseases and conditions of the brain, spine, heart, lungs, and other internal organs.
How is Lopidam administered?
Lopidam is an injectable contrastmedium and is administered intravenously or intra-arterially.
What are the side effects of Lopidam?
Common side effects of Lopidam include allergic reactions such as rash, hives, difficulty breathing, swelling of the face, lips, tongue, or throat, fever, chills, chest pain, nausea, vomiting, increased heart rate, or shock.
What should I tell my doctor before taking Lopidam?
Tell your doctor if you have a history of allergies to contrast media or have had an adverse reaction to previous contrast media injections. Also tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.
What should I do if I experience an allergic reaction to Lopidam?
If you experience an allergic reaction, you should stop the injection immediately and notify your doctor. You should also seek immediate medical attention.
What precautions should I take before receiving an Lopidam injection?
Ask your doctor about any medications you are taking that may interact with Lopidam, such as certain antibiotics or sedatives. Also, make sure to drink plenty of fluids before and after the injection.
What is the recommended dose of Lopidam?
The recommended dose of Lopidam depends on the type of examination being done and the type of scanner used. Your doctor will determine the appropriate dose for you.
Can I receive Lopidam if I have other medical conditions?
Yes, but it is important to tell your doctor about all of your medical conditions prior to receiving Lopidam. Your doctor will determine if Lopidam is safe for you.
How long does Lopidam stay in the body?
Lopidam is cleared from the body within 48 hours. It is mostly excreted in the urine.
Is Lopidam available in a generic form?
No, Lopidam is only available as a brand-name medication.
Where can I get more information about Lopidam?
Your doctor can provide more information about Lopidam and other iodinated contrast media.
Are there any alternatives to Lopidam?
Yes, other iodinated contrast media are available including iomeprol, iohexol, and iopromide.
What should I do if I miss a dose of Lopidam?
Lopidam is only used for x-ray and CT scan examinations and you are unlikely to miss a dose. However, if you have an appointment for an examination and do not receive the injection, contact your doctor.
Is Lopidam safe for children?
Yes, Lopidam is safe for use in children, but the dose is usually lower than it is for adults. Your doctor will determine the appropriate dose for your child.
Can I drive after receiving an Lopidam injection?
It is not recommended to drive after receiving an Lopidam injection due to the possibility of an allergic reaction or other side effects.
What should I do if I experience pain or swelling at the injection site?
It is not uncommon to experience some pain or swelling at the injection site. Contact your doctor if the pain or swelling persists or is severe.
Can I drink alcohol while taking Lopidam?
It is not recommended to drink alcohol while taking Lopidam.
Are there any foods I should avoid while taking Lopidam?
You should avoid eating foods high in iodine while taking Lopidam. Examples include seafood, dairy, eggs, and foods fortified with iodine.
Is Lopidam known to cause birth defects?
There is no known risk of birth defects associated with Lopidam.
Can I take other medications while taking Lopidam?
It is important to tell your doctor about all medications you are taking. Certain antibiotics, sedatives, and other medications may interact with Lopidam.
Are there any long-term effects of taking Lopidam?
There are no long-term effects associated with taking Lopidam.
Should I be concerned about radiation exposure from Lopidam?
No, the level of radiation exposure from Lopidam is not considered to be hazardous.
Are there any over-the-counter treatments for conditions that Lopidam can help diagnose?
No, over-the-counter treatments are not available for conditions that Lopidam can help diagnose. Your doctor will be able to provide more information.
What should I do if I experience a headache or dizziness after taking Lopidam?
Contact your doctor if you experience a headache or dizziness after taking Lopidam.
Can I take Lopidam if I have a history of kidney disease?
Yes, but your doctor may monitor your kidney function closely while you take Lopidam.
Should I stop taking Lopidam if I experience nausea or vomiting?
Contact your doctor if you experience nausea or vomiting while taking Lopidam.
Is there a risk of infection associated with taking Lopidam?
No, there is no known risk of infection associated with taking Lopidam.
What are the storage requirements for Lopidam?
Lopidam should be stored at room temperature away from direct sunlight and heat.
What should I do if I experience an irregular heart beat after taking Lopidam?
Contact your doctor if you experience an irregular heart beat after taking Lopidam.
Can I take Lopidam if I have high blood pressure?
Yes, but your doctor may monitor your blood pressure closely while you take Lopidam.
Is there a risk of anaphylaxis associated with Lopidam?
Yes, there is a risk of anaphylaxis associated with Lopidam. Seek immediate medical attention if you experience any signs of an allergic reaction such as rash, hives, difficulty breathing, swelling of the face, lips, tongue, or throat.
Is Lopidam safe for pregnant women?
Lopidam is usually not recommended during pregnancy. Talk to your doctor about the risks and benefits of using Lopidam during pregnancy.
Can I receive an Lopidam injection if I am breastfeeding?
Lopidam has not been studied in breastfeeding women, and it is not known if it is safe to use while breastfeeding. Talk to your doctor about the risks and benefits of using Lopidam while breastfeeding.
Is there a risk of kidney damage associated with Lopidam?
There is a risk of kidney damage associated with Lopidam, especially in people with a history of kidney disease. Your doctor may monitor your kidney function while you take Lopidam.
Can I receive an Lopidam injection if I have an implanted medical device?
Yes, but it is important to inform your doctor if you have an implanted medical device prior to receiving an Lopidam injection. Your doctor may take additional precautions during the examination to reduce any risk of interference from the device.
What should I do if I have a fever after taking Lopidam?
Contact your doctor if you have a fever after taking Lopidam. It is important to seek medical attention if your fever persists or is severe.
Can I receive Lopidam if I have an adverse reaction to other contrast media?
If you have had an adverse reaction to other contrast media, it is important to inform your doctor before receiving Lopidam. Your doctor may take additional precautions to help reduce any possibility of an allergic reaction.
Can I receive Lopidam if I have a history of allergy to iodinated contrast media?
Yes, but it is important to inform your doctor if you have a history of allergy to iodinated contrast media prior to receiving Lopidam. Your doctor may take additional precautions to help reduce the risk of an allergic reaction.
Is there a risk of blood clotting associated with Lopidam?
No, there is no known risk of blood clotting associated with Lopidam.