Locular Plus
Locular Plus Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Locular Plus is a brand name. Its generic name is Brimonidine + Timolol.
Introduction
Locular Plus is a combination medication used to decrease intraocular pressure (IOP) in open-angle glaucoma and ocular hypertension. It is a combination of a beta-blocker (timolol) and an alpha-agonist (brimonidine).Uses
Locular Plus is used to lower high pressure inside the eye that is caused by glaucoma or other eye conditions. Lowering high pressure helps prevent blindness.Mechanism of Action
Locular Plus works by decreasing the production of fluid inside the eye, resulting in lower eye pressure. While brimonidine works by decreasing the activity of ciliary processes which decreases the production of aqueters; timolol works by blocking beta receptors in the ciliary processes, thus decreasing the production of aqueous humor.How long does it take to work?
Locular Plus can take several weeks to reach it peak effectiveness. It is important to continue taking the medication as prescribed, even if you do not notice an immediate change.Absorption
Locular Plus is rapidly absorbed into the bloodstream when taken orally or when administered topically to the eye.Route of Elimination
Locular Plus are both eliminated primarily through the urine.Dosage
The dosage of Locular Plus for adults and children 16 years of age or older is one drop of 0.5%/0.5% ophthalmic solution in the affected eye(s) twice daily. The dosage for pediatric patients (ages 2-16 years) is one drop of 0.2%/0.5% ophthalmic solution in the affected eye(s) twice daily.Administration
Locular Plus should be administered to the affected eye(s) twice daily, approximately 12 hours apart. After removing the protective cap, the dropper tip should be gently pressed against the inner corner of the eye and held there for one to two minutes before releasing. The dropper should not touch anything as this can cause contamination with bacteria.Side effects
Common side effects of Locular Plus may include: redness or irritation of the eyes, dry eyes, blurred vision, headache, burning or stinging sensation in the eyes, and eye fatigue.Toxicity
If too much Locular Plus is taken, it can be toxic. Symptoms of overdose may include dizziness, drowsiness, confusion, stomach pain, vomiting, headache, tremor, and shortness of breath. If any of these symptoms occur, contact your healthcare provider right away.Precaution
Brimonidine should be used with caution in people with a history of eye surgery, severe kidney or liver disease, thyroid problems, asthma, diabetes and heart problems. Timolol should be used with caution in the elderly, people with poor circulation, and those with a history of heart problems.Interaction
The concomitant use of Locular Plus with other topical ophthalmic medication is not recommended. Additionally, the concomitant use of Locular Plus with medications that can decrease heart rate or blood pressure can result in increased side effects such as headache, dizziness, and fatigue.Disease Interaction
It is not recommended for use in people with severe inflammation of the eye, narrow angle glaucoma, and in those with known hypersensitivity to Brimonidine or Timolol.Drug Interaction
Locular Plus should not be used concomitantly with other topical ophthalmic medication or systemic drugs that can decrease heart rate or blood pressure. Additionally, avoid taking Locular Plus with other medications that contain brimonidine, timolol or other beta blockers.Food Interactions
No food interactions have been reported with the use of Locular Plus.Pregnancy Use
Locular Plus is not recommended for use during pregnancy as the safety of the medication has not been established.Lactation Use
It is not recommended for use in breastfeeding women as it may accumulate in the breast milk and cause adverse effects in nursing babies.Acute Overdose
If an overdose occurs, the patient should seek medical attention immediately. Symptoms of overdose may include dizziness, drowsiness, confusion, stomach pain, vomiting, headache, tremor, and shortness of breath.Contraindication
Locular Plus is contraindicated for use in people with severe inflammation of the eye, narrow angle glaucoma, and in those with known hypersensitivity to Brimonidine or Timolol.Use Directions
Locular Plus should be administered to the affected eye(s) twice daily, approximately 12 hours apart. After removing the protective cap, the dropper tip should be gently pressed against the inner corner of the eye and held there for one to two minutes before releasing. The dropper should not touch anything as this can cause contamination with bacteria.Storage Conditions
Locular Plus should be stored at room temperature, away from heat, light, and moisture.Volume of Distribution
Locular Plus are both highly lipophilic and have a large volume of distribution.Half-life
The half-life of Brimonidine is 2.8 hours, while the half-life of Timolol is 5-7 hours.Clearance
The clearance of Locular Plus is mainly through the kidneys.Here you find in details version of Locular Plus
Some Frequently Asked Questions About Locular Plus
What is Locular Plus?
Locular Plus is a combination eye drop used to reduce intraocular pressure in people with glaucoma. It contains a combination of brimonidine tartrate and timolol maleate which are both medications used to treat eye pressure.
How does Locular Plus work?
Brimonidine and timolol are both medications used to reduce intraocular pressure. Brimonidine is a type of alpha agonist which works by decreasing fluid production in the eye while timolol is a beta blocker which reduces the drainage of fluid from the eye. This combination of medications works by reducing the amount of fluid in the eye, resulting in a decrease in intraocular pressure.
Who should use Locular Plus?
Locular Plus is used to reduce intraocular pressure in people with glaucoma. It is not recommended for people who are pregnant, breastfeeding, or have asthma. It is important for people to discuss their medical history with their doctor and to follow all instructions before using this medication.
What are the side effects of Locular Plus?
The most common side effects of Locular Plus include burning, stinging, dryness of the eyes, eye redness, and blurred vision. Other side effects may include dizziness, headache, and fatigue. If any serious side effects occur, such as confusion or difficulty breathing, seek medical attention immediately.
When should I use Locular Plus?
Locular Plus should be used as directed by your doctor. The usual recommended dosing is 1 drop in each affected eye twice a day. It should be used at the same time each day, about 12 hours apart. Try to use this medication at the same time each day in order to maintain an even level of the medication in the blood.
What should I avoid while using Locular Plus?
It is important to avoid certain activities while using Locular Plus. Avoid contact lenses and eye makeup while using this medication, as these can increase the risk of side effects. Also, it is important to avoid driving or operating heavy machinery while using this medication as it can cause drowsiness and blurred vision.
Is there anything I should tell my doctor before using Locular Plus?
Yes, it is important to tell your doctor about any other medications you are currently taking including prescriptions, over-the-counter medications, vitamins, and supplements as they may interact with Locular Plus. Additionally, inform your doctor of any medical conditions you have, such as heart disease, asthma, or diabetes as these can affect how this medication affects your body.
Can I use Locular Plus with other eye drops?
It is not recommended to use multiple eye drops at the same time, as this can increase the risk of side effects. Speak to your doctor before using any additional eye drops while taking Locular Plus. Your doctor may advise to wait at least 10 minutes between using different eye drops.
Is it safe to use Locular Plus long-term?
Yes, Locular Plus is generally safe to use long-term, provided it is taken as directed by your doctor. It is important to discuss any concerns with your doctor and to report any adverse effects that may occur.
What happens if I forget to take a dose of Locular Plus?
If you forget to take a dose of Locular Plus, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not use a double dose to make up for a missed dose.
Can Locular Plus cause vision problems?
Locular Plus can cause vision problems such as blurred vision, double vision, and halo vision. If you experience any of these vision problems, stop using this medication and inform your doctor right away.
Can I wear contact lenses while using Locular Plus?
No, it is not recommended to wear contact lenses while using Locular Plus. This medication can cause vision changes and should be used with caution if wearing contact lenses.
Is Locular Plus safe for children?
Locular Plus is not recommended for use in children under the age of 18. Speak to a doctor if your child has been prescribed this medication.
Can I drink alcohol while using Locular Plus?
It is not recommended to drink alcohol while using Locular Plus. Alcohol can increase the risk of side effects and can make the medication less effective. Speak to your doctor if you are unsure.
Is Locular Plus covered by insurance?
It depends on your insurance plan. Check with your insurance provider to find out if Locular Plus is covered by your plan.
What should I do if I experience an allergic reaction after using Locular Plus?
If you experience an allergic reaction after using Locular Plus, such as hives, swelling, rash, difficulty breathing, contact your doctor or seek medical help right away.
Is Locular Plus safe to use while pregnant or breastfeeding?
Locular Plus is not recommended for use by pregnant or breastfeeding women. Speak to your doctor if you are pregnant or breastfeeding and need to use this medication.
What will happen if I overdose on Locular Plus?
If you suspect an overdose, you should seek medical help immediately. Overdosing on Locular Plus can cause severe side effects and could be life-threatening. Symptoms of an overdose may include drowsiness, confusion, and difficulty breathing.
What should I do if I get the Locular Plus in my eye?
If you get Locular Plus in your eye, you should flush your eye with water and contact your doctor right away. Do not use contact lenses until your doctor has recommended to do so.
Is Locular Plus the same as Latanoprost?
No, Locular Plus and Latanoprost are different medications. Locular Plus is a combination eye drop used to reduce intraocular pressure in people with glaucoma while Latanoprost is an eye drop used to reduce high pressure in the eye.
What should I do if I accidentally miss a dose of Locular Plus?
If you miss a dose of Locular Plus, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not use a double dose to make up for a missed dose.
Will I still need to go to the eye doctor while I'm taking Locular Plus?
Yes, it is important to go to the eye doctor for regular check-ups even while taking Locular Plus to monitor your eye pressure. Your doctor will be able to determine if the medication is working for you.
Is Locular Plus more effective than Latanoprost?
It is not necessarily more effective than Latanoprost, but it may be more effective for some people. It is important to speak to your doctor about the most effective medication for your eye condition.
Are there any other medications I should not take while using Locular Plus?
It is important to avoid certain medications while using Locular Plus. Do not take beta blockers, albuterol, or any other medications that can reduce blood flow to the eye. Speak to your doctor before taking any new medications.
Are there any foods I should avoid when taking Locular Plus?
It is important to avoid foods high in salt and caffeine when taking Locular Plus. This can make the medication less effective and can increase the risk of side effects. Speak to your doctor before making any major dietary changes.
Can Locular Plus cause an increase in eye pressure?
It is possible for Locular Plus to cause an increase in eye pressure. If you experience an increase in eye pressure, stop using this medication and contact your doctor right away.
Should I wear sunglasses while using Locular Plus?
Yes, it is important to wear sunglasses when going outside while using Locular Plus. This can help protect your eyes from the sun and can reduce the risk of side effects from the medication.
What is the most common side effect of Locular Plus?
The most common side effect of Locular Plus is burning, stinging, dryness of the eyes, eye redness, and blurred vision. Other side effects may include dizziness, headache, and fatigue.
Should I stop taking Locular Plus if I experience side effects?
If you experience any serious or persistent side effects after taking Locular Plus, it is important to contact your doctor right away. Your doctor will be able to advise you on whether to stop taking the medication or adjust your dosage.
What is the best way to store Locular Plus?
Locular Plus should be stored at room temperature, away from direct sunlight and heat. Keep the medication out of reach of children and pets. Do not freeze the medication and do not use the product if it has expired.
Can I wear eye makeup while using Locular Plus?
No, it is not recommended to wear eye makeup while using Locular Plus. This medication can cause vision changes and should be used with caution if wearing eye makeup.
When should I expect to see results after taking Locular Plus?
It can take several days to a few weeks to see results after taking Locular Plus. It is important to use the medication as directed by your doctor to ensure that the medication is working for you.
Can I split the doses of Locular Plus?
No, it is not recommended to split the doses of Locular Plus. Take the medication as directed by your doctor and do not change the dose without speaking to your doctor.
Does Locular Plus have any interactions with other medications?
Yes, Locular Plus can interact with other medications. It is important to tell your doctor about any other medications you are taking including prescriptions, over-the-counter medications, vitamins, and supplements. These may interact with Locular Plus and could cause serious side effects.
Can Locular Plus cause changes in blood pressure?
Yes, Locular Plus can cause changes in blood pressure. It is important to monitor your blood pressure regularly and inform your doctor if you experience any changes.
Can Locular Plus cause an increase in heart rate?
Yes, Locular Plus can cause an increase in heart rate. If you experience an increase in heart rate, contact your doctor right away.
What should I do if I forget to use Locular Plus one day?
If you forget to use Locular Plus one day, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not use a double dose to make up for a missed