Lipigem
Lipigem Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Lipigem is a brand name. Its generic name is Gemfibrozil.
Introduction
Lipigem is a prescription medication used to reduce cholesterol levels and treat hypertriglyceridemia (high levels of triglycerides in the blood). It belongs to a class of drugs called fibrates which can help to decrease triglycerides, increase "good" cholesterol (HDL) and slow the buildup of fatty substances in the arteries.Uses
Lipigem is approved by the U.S Food and Drug Administration to be used in adults to lower triglyceride levels and/or total cholesterol levels. It is used in combination with diet to reduce the risk of coronary heart disease and associated symptoms such as heart attack and stroke. The drug may be used to control levels of non-HDL cholesterol and lipoprotein(a).Mechanism of Action
Lipigem works by affecting the metabolism of certain fats and lipids released by the liver. It helps to reduce the production of triglycerides, raise the level of “good” cholesterol (HDL) and prevent the build-up of fatty substances in the arteries.How Long Does it Take to Work?
Lipigem typically starts to work within 2-4 weeks after it is started. It is important to follow a low-fat diet and other lifestyle changes while taking the medication to see the desired effects.Absorption
Lipigem is well absorbed from the gastrointestinal tract after oral administration, with peak plasma concentrations occurring at 2-4 hours. The oral bioavailability of this drug is very high, with about 98% of an oral dose being absorbed.Route of Elimination
Lipigem is eliminated mainly through the feces. About 90% of the dose is excreted in the feces, with the remainder excreted in the urine.Dosage and Administration
The recommended dose of Lipigem for adults 18 years and older is 600 mg taken orally twice daily, one hour before or two hours after meals. It can be taken with or without food, but should not be eaten with high-fat meals or grapefruit juice.Side Effects
Lipigem can cause side effects such as stomach pain, heartburn, decreased appetite, nausea, diarrhea, and constipation. It can also cause rash, muscle aches, fever, increased liver enzymes, and increased cholesterol levels.Precautions
Lipigem should not be used in people with active liver disease or in individuals with a known hypersensitivity to fibrates. This medication should also be used with caution in people with a history of kidney or gallbladder disease.Interactions
Lipigem can interact with other medications used to lower cholesterol, anticoagulants, acetaminophen, theophylline, and atorvastatin. Always tell your doctor about all the medications you are taking.Food Interactions
Lipigem can interact with certain foods, such as grapefruit juice, which should be avoided.Pregnancy and Lactation
Lipigem is classified as a category C drug which means that it should not be used during pregnancy as it may cause harm to the fetus. It is also not recommended to be used during breastfeeding.Acute Overdose
Signs and symptoms of an overdose of Lipigem include nausea, vomiting, stomach pain, diarrhea, dizziness, and confusion. Seek immediate medical attention if you experience any of these symptoms.Contraindication
Lipigem is contraindicated for use in people with active liver disease or in individuals with a known hypersensitivity to fibrates.Use Direction
Take Lipigem exactly as prescribed by your doctor. Follow all directions on the prescription label. Do not take this medicine in larger or smaller amounts than prescribed.Storage Conditions
Lipigem should be stored at room temperature between 15°C and 30°C and protected from light and moisture. Do not store this medication in the bathroom.Volume of Distribution
The volume of distribution of Lipigem is approximately 1.8 L/kg.Half Life
The average half-life of Lipigem is about 5-14 hours.Clearance
The clearance of Lipigem is about 0.7 L/hr/kg.Here you find in details version of Lipigem
Some Frequently Asked Questions About Lipigem
then you can provide 20 FAQWhat is Lipigem?
Lipigem is a prescription medication used to reduce cholesterol and triglyceride levels in adults with hypertriglyceridemia.
How does Lipigem work?
Lipigem works by inhibiting enzymes in the liver that are responsible for producing cholesterol and triglycerides, thus reducing their levels in the blood.
What are the side effects of Lipigem?
Common side effects of Lipigem include nausea, vomiting, stomach pain, gas, constipation, diarrhea, headache, dizziness, and rash.
Is Lipigem safe to use?
Lipigem is generally safe to use when taken as directed by a doctor. However, there are some reported side effects and it is important to talk to your doctor to understand these risks.
How long do I need to take Lipigem?
Lipigem treatment may need to be taken over a long period of time. Your doctor will advise you on how long you need to take the medication.
How should I take Lipigem?
Lipigem should be taken with food twice a day, usually in the morning and evening. It is important to take it at the same time each day, and to take it with food to decrease the risk of stomach upset.
What should I do if I forget to take a dose of Lipigem?
If you forget to take a dose of Lipigem, take it as soon as you remember, unless it is close to your next dose. If it is close to your next dose, skip the missed dose and just take the next dose as usual.
Is Lipigem safe to take with other medications?
Lipigem may interact with other medications, so it is important to tell your doctor if you are taking any other medication to avoid any potential interactions.
What should I discuss with my doctor before taking Lipigem?
Before taking Lipigem, be sure to tell your doctor if you have any other medical conditions or allergies, if you are pregnant or breastfeeding, and about any other medications you are taking.
What should I avoid while taking Lipigem?
It is important to avoid drinking alcohol while taking Lipigem, as it can increase the risk of side effects. Other than that, you should follow your doctor's instructions.
What is the usual dosage of Lipigem?
The usual dosage of Lipigem is one 600 mg tablet taken twice daily with meals. Your doctor may adjust your dosage depending on your response to the medication.
Can I take Lipigem with other types of cholesterol medications?
Yes, Lipigem can be taken in conjunction with other types of cholesterol medications, but it is important that you talk to your doctor first to ensure it is safe.
Are there any supplements I should avoid while taking Lipigem?
If you are taking Lipigem, it is best to avoid taking large doses of magnesium supplements, as this can increase the risk of side effects. If you are taking any other supplements, it is best to talk to your doctor first.
What are the benefits of taking Lipigem?
Lipigem can help reduce cholesterol and triglyceride levels, which can reduce the risk of developing heart disease, stroke, and other cardiovascular illnesses.
Can I take Lipigem while pregnant?
No, Lipigem is not recommended for pregnant women, as it can cause harm to the fetus. Be sure to talk to your doctor if you are pregnant or planning to become pregnant.
Should I exercise while taking Lipigem?
Yes, it is recommended to exercise regularly while taking Lipigem, as this can help to further reduce cholesterol levels and improve your overall health.
Are there any foods I should avoid while taking Lipigem?
You should avoid foods that are high in saturated fats and cholesterol, such as fatty meats, fried foods, and whole-milk dairy products. Additionally, you should avoid drinking excessive amounts of alcohol while taking Lipigem.
Can I take Lipigem if I am taking other medications?
Lipigem can interact with other medications, so it is important to tell your doctor if you are taking any other medications, supplements, or herbs. Be sure to follow your doctor's instructions and avoid any potential interactions.
What should I avoid eating while taking Lipigem?
You should avoid foods that are high in saturated fats and cholesterol, such as fatty meats, fried foods, and whole-milk dairy products. Additionally, you should avoid drinking excessive amounts of alcohol while taking Lipigem.
How should I store Lipigem?
Lipigem should be stored at room temperature, away from direct sunlight and moisture. Be sure to keep the medication in a secure place where children and pets cannot access it.
How quickly does Lipigem start working?
Lipigem starts working quickly, though the full effects may take several weeks to become noticeable. Be sure to follow your doctor's instructions and continue taking the medication even if you do not notice any effects.
What are the most common side effects of Lipigem?
Common side effects of Lipigem include nausea, vomiting, stomach pain, gas, constipation, diarrhea, headache, dizziness, and rash.
Is Lipigem available in generic form?
Yes, Lipigem is available in both brand-name and generic forms.
What happens if I overdose on Lipigem?
If you believe you may have overdosed on Lipigem, contact your doctor or Poison Control immediately. Overdosing on Lipigem can be dangerous and lead to serious medical complications.
Can I take Lipigem more than twice a day?
No, it is not recommended to take Lipigem more than twice a day. It is important to follow your doctor's instructions to ensure safe and effective use.
Should I take Lipigem with food?
Yes, it is important to take Lipigem with food to decrease the risk of stomach upset. You should take it with a meal twice daily, usually in the morning and evening.
Does Lipigem have any long-term effects?
Though Lipigem is generally safe to use long-term, it may cause rare and serious side effects such as nerve tissue damage, liver damage, and muscle damage. Be sure to talk to your doctor immediately if you experience any unexpected side effects.
Can I take Lipigem if I have diabetes?
Yes, you can take Lipigem if you have diabetes. However, it is important to talk to your doctor to ensure it is safe for you to take.
Should I take Lipigem with a low-fat diet?
Yes, maintaining a low-fat diet can help to reduce your cholesterol and triglyceride levels, so it is recommended to eat a diet low in saturated fats while taking Lipigem.
What if my cholesterol and triglycerides don't lower while taking Lipigem?
If your cholesterol and triglyceride levels don't lower while taking Lipigem, talk to your doctor about adjusting your dosage or taking other medications.
Can I drink alcohol while taking Lipigem?
No, it is not recommended to drink alcohol while taking Lipigem, as it can increase the risk of side effects.
Can Lipigem be used to treat high blood pressure?
No, Lipigem is not used to treat high blood pressure. High blood pressure is usually treated with medications such as ACE inhibitors, diuretics, beta blockers, and calcium channel blockers.
Can I take Lipigem without food?
No, it is not recommended to take Lipigem without food as this can increase the risk of stomach upset. Be sure to take it with food twice a day, usually in the morning and evening.
Do I need to have regular blood tests while taking Lipigem?
Yes, it is important to have regular blood tests while taking Lipigem to ensure that it is working properly and to monitor for any potential side effects.
Does Lipigem cause weight gain?
No, Lipigem does not typically cause weight gain. However, some people may experience weight gain as a side effect. Talk to your doctor if you are concerned about weight gain while taking Lipigem.
What other medications can interact with Lipigem?
Lipigem can interact with a variety of other medications, so it is important to talk to your doctor if you are taking any medications. This includes prescription and non-prescription medications, supplements, and herbs.
Can I take Lipigem if I have an allergy to sulfa drugs?
No, Lipigem contains sulfates and should not be taken if you have any type of allergy to sulfa drugs. Be sure to talk to your doctor about your allergies before starting treatment with Lipigem.
Does Lipigem increase my risk of developing diabetes?
No, Lipigem does not increase the risk of diabetes. However, it is important to talk to your doctor if you have any concerns.
Are there any foods I should not eat while taking Lipigem?
You should avoid foods that are high in saturated fats and cholesterol, such as fatty meats, fried foods, and whole-milk dairy products. Additionally, you should avoid drinking excessive amounts of alcohol while taking Lipigem.